IT1276781B1 - Derivati antrachinonmono- e disolfon- sostituiti e composizioni farmaceutiche che li contengono per il trattamento delle patologie - Google Patents
Derivati antrachinonmono- e disolfon- sostituiti e composizioni farmaceutiche che li contengono per il trattamento delle patologieInfo
- Publication number
- IT1276781B1 IT1276781B1 IT95MI001357A ITMI951357A IT1276781B1 IT 1276781 B1 IT1276781 B1 IT 1276781B1 IT 95MI001357 A IT95MI001357 A IT 95MI001357A IT MI951357 A ITMI951357 A IT MI951357A IT 1276781 B1 IT1276781 B1 IT 1276781B1
- Authority
- IT
- Italy
- Prior art keywords
- treatment
- disolfon
- anthrachinonmon
- diseases
- pct
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 210000002805 bone matrix Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000003628 erosive effect Effects 0.000 abstract 1
- FUZZWVXGSFPDMH-UHFFFAOYSA-N hexanoic acid Chemical compound CCCCCC(O)=O FUZZWVXGSFPDMH-UHFFFAOYSA-N 0.000 abstract 1
- 201000008482 osteoarthritis Diseases 0.000 abstract 1
- 230000007170 pathology Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/17—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Silver Salt Photography Or Processing Solution Therefor (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Priority Applications (16)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT95MI001357A IT1276781B1 (it) | 1995-06-23 | 1995-06-23 | Derivati antrachinonmono- e disolfon- sostituiti e composizioni farmaceutiche che li contengono per il trattamento delle patologie |
| SK1760-97A SK281853B6 (sk) | 1995-06-23 | 1996-06-17 | Použitie mono- a disulfo-substituovaných antrachinónov, zlúčeniny, ich spôsob výroby a farmaceutický prostriedok s ich obsahom |
| ES96922001T ES2193248T3 (es) | 1995-06-23 | 1996-06-17 | Antraquinonas mono- y disulfosustituidas y su uso para el tratamiento de desordenes de la matriz osea. |
| DE69626514T DE69626514T2 (de) | 1995-06-23 | 1996-06-17 | Mono-und disulfosubstituierte anthrachinone und deren verwendung zur behandlung von knochenmatrixerkrankungen |
| PCT/EP1996/002597 WO1997000675A1 (en) | 1995-06-23 | 1996-06-17 | Mono- and disulfo-substituted anthraquinones and their use for the treatment of bone matrix disorders |
| DK96922001T DK0833626T3 (da) | 1995-06-23 | 1996-06-17 | Mono- og disulfosubstituerede anthraquioner og deres anvendelse til behandlingen af knoglematrixforstyrrelser |
| CA002225277A CA2225277A1 (en) | 1995-06-23 | 1996-06-17 | Mono- and disulfo-substituted anthraquinones and their use for the treatment of bone matrix disorders |
| RU98101090/14A RU2202534C2 (ru) | 1995-06-23 | 1996-06-17 | Моно- и дисульфозамещенные антрахиноны и их применение для лечения нарушений костного матрикса |
| US08/981,287 US5856358A (en) | 1995-06-23 | 1996-06-17 | Mono- and disulfo-substituted anthraquinones and their use for the treatment of bone matrix disorders |
| AT96922001T ATE233553T1 (de) | 1995-06-23 | 1996-06-17 | Mono-und disulfosubstituierte anthrachinone und deren verwendung zur behandlung von knochenmatrixerkrankungen |
| JP50356397A JP3307650B2 (ja) | 1995-06-23 | 1996-06-17 | モノ−およびジスルホ置換アントラキノンおよび骨基質疾患の治療のためのそれらの使用 |
| PT96922001T PT833626E (pt) | 1995-06-23 | 1996-06-17 | Antraquinonas mono- e di-sulfo- substituidas e a sua utilizacao para o tratamento de disturbios da matriz do osso |
| AU63039/96A AU6303996A (en) | 1995-06-23 | 1996-06-17 | Mono- and disulfo-substituted anthraquinones and their use for the treatment of bone matrix disorders |
| CZ19974193A CZ293326B6 (cs) | 1995-06-23 | 1996-06-17 | Použití mono- a disulfosubstituovaných anthrachinonů pro přípravu léčiva, mono- a disulfosubstituované anthrachinony, způsob jejich přípravy a farmaceutický prostředek |
| EP96922001A EP0833626B1 (en) | 1995-06-23 | 1996-06-17 | Mono- and disulfo-substituted anthraquinones and their use for the treatment of bone matrix disorders |
| MX9800049A MX9800049A (es) | 1995-06-23 | 1998-01-07 | Antraquinonas mono- y disulfo-substituidas y su uso para el tratamiento de trastornos de la matriz del hueso. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT95MI001357A IT1276781B1 (it) | 1995-06-23 | 1995-06-23 | Derivati antrachinonmono- e disolfon- sostituiti e composizioni farmaceutiche che li contengono per il trattamento delle patologie |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI951357A0 ITMI951357A0 (it) | 1995-06-23 |
| ITMI951357A1 ITMI951357A1 (it) | 1996-12-23 |
| IT1276781B1 true IT1276781B1 (it) | 1997-11-03 |
Family
ID=11371864
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT95MI001357A IT1276781B1 (it) | 1995-06-23 | 1995-06-23 | Derivati antrachinonmono- e disolfon- sostituiti e composizioni farmaceutiche che li contengono per il trattamento delle patologie |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5856358A (it) |
| EP (1) | EP0833626B1 (it) |
| JP (1) | JP3307650B2 (it) |
| AT (1) | ATE233553T1 (it) |
| AU (1) | AU6303996A (it) |
| CA (1) | CA2225277A1 (it) |
| CZ (1) | CZ293326B6 (it) |
| DE (1) | DE69626514T2 (it) |
| DK (1) | DK0833626T3 (it) |
| ES (1) | ES2193248T3 (it) |
| IT (1) | IT1276781B1 (it) |
| MX (1) | MX9800049A (it) |
| PT (1) | PT833626E (it) |
| RU (1) | RU2202534C2 (it) |
| SK (1) | SK281853B6 (it) |
| WO (1) | WO1997000675A1 (it) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9608133D0 (en) * | 1996-04-19 | 1996-06-26 | Gemini International Holdings | Diagnostic method and apparatus |
| FR2757397B1 (fr) * | 1996-12-23 | 1999-03-05 | Mazal Pharma | Composition pharmaceutique a base de rheine ou de diacerheine a biodisponibilite amelioree |
| JPH11236333A (ja) * | 1997-12-30 | 1999-08-31 | Pfizer Prod Inc | 抗ガン剤として有用なイミダゾリン−４−オン誘導体 |
| US6117869A (en) * | 1998-08-04 | 2000-09-12 | Warner-Lambert Company | Compounds for and methods of inhibiting matrix metalloproteinases |
| US6174903B1 (en) | 1998-12-28 | 2001-01-16 | Pfizer Inc. | Imidazolidin-4-one derivatives useful as anticancer agents |
| US6610750B1 (en) * | 2000-09-15 | 2003-08-26 | Laboratoires Negma | Treatment of osteoarthritis |
| AUPR229600A0 (en) * | 2000-12-22 | 2001-01-25 | Commonwealth Scientific And Industrial Research Organisation | New oxygen scavenging compositions |
| US6600057B2 (en) * | 2000-12-29 | 2003-07-29 | Kimberly-Clark Worldwide, Inc. | Matrix metalloproteinase inhibitors |
| CA2695504C (en) * | 2007-08-03 | 2017-05-30 | Nucitec S.A. De C.V. | Compositions and methods for treatment and prevention of osteoarthritis |
| WO2011066263A1 (en) * | 2009-11-24 | 2011-06-03 | The Ohio State University | Transcription factor inhibitors and related compositions, formulations and methods |
| AU2011237600B2 (en) * | 2010-04-08 | 2016-06-23 | Twi Biotechnology, Inc. | Methods of using diacerein as an adjunctive therapy for diabetes |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2025954A (en) * | 1978-07-21 | 1980-01-30 | Ciba Geigy Ag | Anthraquinone Sulphonamides |
| IT1244773B (it) * | 1991-03-12 | 1994-08-08 | Gentili Ist Spa | N-(4,5-diidrossi-e 4,5,8-triidrossi-9,10-diidro-9,10-diosso-2- antracen-il)carbonil) amminoacidi utilizzabili nella terapia delle affezioni osteoarticolari |
-
1995
- 1995-06-23 IT IT95MI001357A patent/IT1276781B1/it active IP Right Grant
-
1996
- 1996-06-17 CZ CZ19974193A patent/CZ293326B6/cs not_active IP Right Cessation
- 1996-06-17 RU RU98101090/14A patent/RU2202534C2/ru not_active IP Right Cessation
- 1996-06-17 AU AU63039/96A patent/AU6303996A/en not_active Abandoned
- 1996-06-17 AT AT96922001T patent/ATE233553T1/de not_active IP Right Cessation
- 1996-06-17 EP EP96922001A patent/EP0833626B1/en not_active Expired - Lifetime
- 1996-06-17 PT PT96922001T patent/PT833626E/pt unknown
- 1996-06-17 WO PCT/EP1996/002597 patent/WO1997000675A1/en not_active Ceased
- 1996-06-17 CA CA002225277A patent/CA2225277A1/en not_active Abandoned
- 1996-06-17 JP JP50356397A patent/JP3307650B2/ja not_active Expired - Fee Related
- 1996-06-17 ES ES96922001T patent/ES2193248T3/es not_active Expired - Lifetime
- 1996-06-17 SK SK1760-97A patent/SK281853B6/sk unknown
- 1996-06-17 DK DK96922001T patent/DK0833626T3/da active
- 1996-06-17 US US08/981,287 patent/US5856358A/en not_active Expired - Fee Related
- 1996-06-17 DE DE69626514T patent/DE69626514T2/de not_active Expired - Fee Related
-
1998
- 1998-01-07 MX MX9800049A patent/MX9800049A/es not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69626514D1 (de) | 2003-04-10 |
| PT833626E (pt) | 2003-07-31 |
| SK176097A3 (en) | 1998-06-03 |
| AU6303996A (en) | 1997-01-22 |
| DK0833626T3 (da) | 2003-06-30 |
| WO1997000675A1 (en) | 1997-01-09 |
| EP0833626B1 (en) | 2003-03-05 |
| SK281853B6 (sk) | 2001-08-06 |
| ES2193248T3 (es) | 2003-11-01 |
| US5856358A (en) | 1999-01-05 |
| JP3307650B2 (ja) | 2002-07-24 |
| ITMI951357A0 (it) | 1995-06-23 |
| RU2202534C2 (ru) | 2003-04-20 |
| CZ419397A3 (cs) | 1998-07-15 |
| JPH11509186A (ja) | 1999-08-17 |
| DE69626514T2 (de) | 2003-12-24 |
| CA2225277A1 (en) | 1997-01-09 |
| ATE233553T1 (de) | 2003-03-15 |
| MX9800049A (es) | 1998-11-30 |
| EP0833626A1 (en) | 1998-04-08 |
| CZ293326B6 (cs) | 2004-04-14 |
| ITMI951357A1 (it) | 1996-12-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted |