[go: up one dir, main page]

IT1254519B - ASSOCIATIONS OF ANTIVIRAL COMPOUNDS - Google Patents

ASSOCIATIONS OF ANTIVIRAL COMPOUNDS

Info

Publication number
IT1254519B
IT1254519B ITMI920605A ITMI920605A IT1254519B IT 1254519 B IT1254519 B IT 1254519B IT MI920605 A ITMI920605 A IT MI920605A IT MI920605 A ITMI920605 A IT MI920605A IT 1254519 B IT1254519 B IT 1254519B
Authority
IT
Italy
Prior art keywords
associations
antiviral compounds
purine
drugs
folic acid
Prior art date
Application number
ITMI920605A
Other languages
Italian (it)
Inventor
Paolo Chiesi
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Priority to ITMI920605A priority Critical patent/IT1254519B/en
Publication of ITMI920605A0 publication Critical patent/ITMI920605A0/en
Priority to AU36320/93A priority patent/AU3632093A/en
Priority to PCT/EP1993/000541 priority patent/WO1993018776A1/en
Publication of ITMI920605A1 publication Critical patent/ITMI920605A1/en
Application granted granted Critical
Publication of IT1254519B publication Critical patent/IT1254519B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Associazioni di farmaci costituite da un analogo di un nucleoside purinico o pirimidinico e da un antagonista competitivo dell'acido folico esplicano un'efficace attività antivirale in particolare nei confronti di Herpes virus.Tale attività si manifesta anche nei confronti di virus mutanti che hanno sviluppato resistenza ai farmaci.Drug combinations consisting of a purine or pyrimidine nucleoside analogue and a competitive folic acid antagonist exhibit effective antiviral activity in particular against Herpes virus, which also occurs against mutant viruses that have developed resistance to drugs.

ITMI920605A 1992-03-16 1992-03-16 ASSOCIATIONS OF ANTIVIRAL COMPOUNDS IT1254519B (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
ITMI920605A IT1254519B (en) 1992-03-16 1992-03-16 ASSOCIATIONS OF ANTIVIRAL COMPOUNDS
AU36320/93A AU3632093A (en) 1992-03-16 1993-03-10 Combinations of compounds having antiviral activity
PCT/EP1993/000541 WO1993018776A1 (en) 1992-03-16 1993-03-10 Combinations of compounds having antiviral activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI920605A IT1254519B (en) 1992-03-16 1992-03-16 ASSOCIATIONS OF ANTIVIRAL COMPOUNDS

Publications (3)

Publication Number Publication Date
ITMI920605A0 ITMI920605A0 (en) 1992-03-16
ITMI920605A1 ITMI920605A1 (en) 1993-09-16
IT1254519B true IT1254519B (en) 1995-09-25

Family

ID=11362445

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI920605A IT1254519B (en) 1992-03-16 1992-03-16 ASSOCIATIONS OF ANTIVIRAL COMPOUNDS

Country Status (3)

Country Link
AU (1) AU3632093A (en)
IT (1) IT1254519B (en)
WO (1) WO1993018776A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19857009A1 (en) * 1998-12-10 2000-06-15 Aventis Pharma Gmbh Preparation with improved therapeutic range, containing nucleotide synthesis inhibitors
GB0123571D0 (en) 2001-04-05 2001-11-21 Aventis Pharm Prod Inc Use of (Z)-2-cyano-3-hydroxy-but-2-enoic acid-(4'-trifluoromethylphenyl)-amide for treating multiple sclerosis
EP3793561B1 (en) * 2018-05-15 2025-03-26 National Centre For Cell Science Methotrexate compounds for use in treating hiv infections
EP4114406A4 (en) * 2019-11-21 2024-02-28 Gaziantep Universitesi Rektörlügu SYNTHESIS AND IMPROVEMENT OF A NUCLEOSIDE ANALOGO AS AN ANTI-CANCER AND ANTIVIRAL DRUG
WO2021240375A1 (en) * 2020-05-26 2021-12-02 Blueprint Pharma S.R.L. Methotrexate for use in the pharmaceutical or veterinary prevention and/or treatment of viral infections

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5116823A (en) * 1990-02-27 1992-05-26 Roger Williams General Hospital Drug combinations containing AZT

Also Published As

Publication number Publication date
WO1993018776A1 (en) 1993-09-30
AU3632093A (en) 1993-10-21
ITMI920605A0 (en) 1992-03-16
ITMI920605A1 (en) 1993-09-16

Similar Documents

Publication Publication Date Title
DE3587434D1 (en) ANTIVIRAL PHARMACEUTICAL COMPOSITIONS AND THEIR USE.
DK654287D0 (en) ANTIVIRAL RELATIONS
FI932870A7 (en) 2'-Deoxy-2'2'-difluoro-(4-substituted pyrimidine) nucleosides with antiviral and anticancer activity, and intermediates
AU4690989A (en) Antiviral cytosine and guanine derivatives
TW366347B (en) Antiviral pharmaceutical compositions comprising 1,3-oxathiolane nucleoside analogues
RU95109100A (en) Derivatives of xanthine, mixture of its isomers and individual isomers and their pharmaceutically acceptable salts and pharmaceutical composition having antagonist in respect with adenosine activity on its base
DE69432087D1 (en) 6-amino-purine derivatives with PDE-IV inhibitory activity
FI20001231L (en) 2-Deoxy-2,3-didehydro-N-acetylneuraminic acid derivatives and their analogues and their use as antiviral agents
BR9815166A (en) "method of inhibiting virus replication, compound, method of inhibiting cytomegalovirus replication, antiviral compound, use of a compound, pharmaceutical composition, pharmaceutical composition inhibiting virus and cytomegalovirus replication and antiviral pharmaceutical composition"
TW366339B (en) Derivatives of benzimidazolyl-cyclopentanediol, -cyclopentanol and -cyclopentenol, and pharmaceutical composition containing the same
IT1254519B (en) ASSOCIATIONS OF ANTIVIRAL COMPOUNDS
ATE160340T1 (en) CONFORMATIONALLY DETERMINED NUCLEOSIDE ANALOGUES
DE3679353D1 (en) ANTIVIRAL CONNECTIONS.
TW371662B (en) Antiviral acyclic phosphonomethoxyalkyl substituted alkenyl purine and pyrimidine derivatives
MX9203217A (en) THERAPEUTIC NUCLEOSIDES.
DE69206102D1 (en) DI (2-PROPYL) ESTERS OF 1-FLUORO-2-PHOSPHONOMETHOXY-3-P-TOLUOL-SULFONYLOXYPROPANE, THEIR PRODUCTION AND USE.
HUP9900945A2 (en) Nucleoside analogs in combinative therapy of herpes simplex infections
DE68914809D1 (en) Antiviral agents.
ATE26267T1 (en) PYRIMIDINE DERIVATIVES, EQUIPPED WITH ANTIVIRAL ACTION.
ITMI910978A0 (en) PYRIMIDINE DERIVATIVES WITH PHARMACOLOGICAL ACTIVITY, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
IT1146724B (en) Purine and pyrimidine cpds.
IT9020027A0 (en) PYRIMIDINE DERIVATIVES WITH PHARMACOLOGICAL ACTIVITY, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM
ITRM910829A0 (en) HYPOXANTHINE DERIVATIVES EQUIPPED WITH IMMUNOMODULANT ACTIVITY AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM