IS5166A - Crystallized aqueous sodium salt of (E) -4,6-dichloro-3- (2-oxo-1-phenylpyrrolidin-3-ylidene methyl) -1H-indole-2-carboxylic acid - Google Patents

Crystallized aqueous sodium salt of (E) -4,6-dichloro-3- (2-oxo-1-phenylpyrrolidin-3-ylidene methyl) -1H-indole-2-carboxylic acid

Info

Publication number: IS5166A
Authority: IS; Iceland
Prior art keywords: phenylpyrrolidin; indole; dichloro; oxo; carboxylic acid
Prior art date: 1997-03-05

Application number

IS5166A

Other languages

Icelandic (is)

Inventor

Cimarosti Zadeo

Maragni Paolo

Original Assignee

Glaxo Wellcome Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-03-05

Filing date

1999-08-27

Publication date

1999-08-27

1999-08-27 Application filed by Glaxo Wellcome Spa filed Critical Glaxo Wellcome Spa

1999-08-27 Publication of IS5166A publication Critical patent/IS5166A/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Neurology (AREA)
Veterinary Medicine (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Indole Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pyrrole Compounds (AREA)

IS5166A 1997-03-05 1999-08-27 Crystallized aqueous sodium salt of (E) -4,6-dichloro-3- (2-oxo-1-phenylpyrrolidin-3-ylidene methyl) -1H-indole-2-carboxylic acid IS5166A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9704498.6A GB9704498D0 (en)	1997-03-05	1997-03-05	Chemical compound
PCT/EP1998/001146 WO1998039327A1 (en)	1997-03-05	1998-03-03	Crystalline hydrated sodium salt of (e)-4,6-dichloro-3-(2-oxo-1-phenylpyrrolidin-3-ylidene methyl)-1h-indole-2-carboxylic acid

Publications (1)

Publication Number	Publication Date
IS5166A true IS5166A (en)	1999-08-27

Family

ID=10808697

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS5166A IS5166A (en)	1997-03-05	1999-08-27	Crystallized aqueous sodium salt of (E) -4,6-dichloro-3- (2-oxo-1-phenylpyrrolidin-3-ylidene methyl) -1H-indole-2-carboxylic acid

Country Status (29)

Country	Link
EP (1)	EP0966463A1 (en)
JP (1)	JP2001513796A (en)
KR (1)	KR20000075907A (en)
CN (1)	CN1249750A (en)
AP (1)	AP9901637A0 (en)
AR (1)	AR011178A1 (en)
AU (1)	AU6825198A (en)
BG (1)	BG103779A (en)
BR (1)	BR9808305A (en)
CA (1)	CA2282851A1 (en)
CO (1)	CO4940415A1 (en)
EA (1)	EA199900710A1 (en)
EE (1)	EE9900387A (en)
GB (1)	GB9704498D0 (en)
HR (1)	HRP980114A2 (en)
HU (1)	HUP0002109A2 (en)
ID (1)	ID24207A (en)
IL (1)	IL131489A0 (en)
IS (1)	IS5166A (en)
NO (1)	NO994303L (en)
NZ (1)	NZ337315A (en)
OA (1)	OA11154A (en)
PE (1)	PE51399A1 (en)
PL (1)	PL335652A1 (en)
SK (1)	SK119699A3 (en)
TR (1)	TR199902117T2 (en)
WO (1)	WO1998039327A1 (en)
YU (1)	YU43499A (en)
ZA (1)	ZA981791B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9704499D0 (en) *	1997-03-05	1997-04-23	Glaxo Wellcome Spa	Method of manufacture
GB9825988D0 (en) *	1998-11-27	1999-01-20	Pfizer Ltd	Indole derivatives
GB9915231D0 (en)	1999-06-29	1999-09-01	Pfizer Ltd	Pharmaceutical complex
US9737531B2 (en)	2012-07-12	2017-08-22	Glytech, Llc	Composition and method for treatment of depression and psychosis in humans
KR102609676B1 (en)	2017-06-12	2023-12-05	글리테크 엘엘씨.	Treatment of depression with NMDA antagonists and D2/5HT2A or selective 5HT2A antagonists

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9321221D0 (en) *	1993-10-14	1993-12-01	Glaxo Spa	Heterocyclic compounds

1997
- 1997-03-05 GB GBGB9704498.6A patent/GB9704498D0/en active Pending
1998
- 1998-03-03 EA EA199900710A patent/EA199900710A1/en unknown
- 1998-03-03 PL PL98335652A patent/PL335652A1/en unknown
- 1998-03-03 EE EEP199900387A patent/EE9900387A/en unknown
- 1998-03-03 YU YU43499A patent/YU43499A/en unknown
- 1998-03-03 AP APAP/P/1999/001637A patent/AP9901637A0/en unknown
- 1998-03-03 AR ARP980100948A patent/AR011178A1/en unknown
- 1998-03-03 EP EP98913613A patent/EP0966463A1/en not_active Withdrawn
- 1998-03-03 PE PE1998000149A patent/PE51399A1/en not_active Application Discontinuation
- 1998-03-03 AU AU68251/98A patent/AU6825198A/en not_active Abandoned
- 1998-03-03 CO CO98011404A patent/CO4940415A1/en unknown
- 1998-03-03 ID IDW990976A patent/ID24207A/en unknown
- 1998-03-03 ZA ZA9801791A patent/ZA981791B/en unknown
- 1998-03-03 BR BR9808305-8A patent/BR9808305A/en not_active Application Discontinuation
- 1998-03-03 CN CN98803053A patent/CN1249750A/en active Pending
- 1998-03-03 NZ NZ337315A patent/NZ337315A/en unknown
- 1998-03-03 JP JP53813598A patent/JP2001513796A/en active Pending
- 1998-03-03 IL IL13148998A patent/IL131489A0/en unknown
- 1998-03-03 CA CA002282851A patent/CA2282851A1/en not_active Abandoned
- 1998-03-03 HU HU0002109A patent/HUP0002109A2/en unknown
- 1998-03-03 WO PCT/EP1998/001146 patent/WO1998039327A1/en not_active Ceased
- 1998-03-03 SK SK1196-99A patent/SK119699A3/en unknown
- 1998-03-03 KR KR1019997007987A patent/KR20000075907A/en not_active Withdrawn
- 1998-03-03 TR TR1999/02117T patent/TR199902117T2/en unknown
- 1998-03-04 HR HR9704498.6A patent/HRP980114A2/en not_active Application Discontinuation
1999
- 1999-08-27 IS IS5166A patent/IS5166A/en unknown
- 1999-09-02 OA OA9900201A patent/OA11154A/en unknown
- 1999-09-03 NO NO994303A patent/NO994303L/en not_active Application Discontinuation
- 1999-10-04 BG BG103779A patent/BG103779A/en unknown

Also Published As

Publication number	Publication date
AU6825198A (en)	1998-09-22
AR011178A1 (en)	2000-08-02
WO1998039327A1 (en)	1998-09-11
OA11154A (en)	2003-04-16
AP9901637A0 (en)	1999-09-30
ZA981791B (en)	1999-09-03
KR20000075907A (en)	2000-12-26
PE51399A1 (en)	1999-06-07
TR199902117T2 (en)	2000-03-21
YU43499A (en)	2000-12-28
EA199900710A1 (en)	2000-04-24
EE9900387A (en)	2000-04-17
PL335652A1 (en)	2000-05-08
JP2001513796A (en)	2001-09-04
NO994303D0 (en)	1999-09-03
CA2282851A1 (en)	1998-09-11
HUP0002109A2 (en)	2001-04-28
ID24207A (en)	2000-07-13
EP0966463A1 (en)	1999-12-29
BR9808305A (en)	2000-05-16
IL131489A0 (en)	2001-01-28
NZ337315A (en)	2001-02-23
CN1249750A (en)	2000-04-05
HRP980114A2 (en)	1998-12-31
SK119699A3 (en)	2000-05-16
NO994303L (en)	1999-11-03
BG103779A (en)	2000-06-30
GB9704498D0 (en)	1997-04-23
CO4940415A1 (en)	2000-07-24

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