IS3994A - An analogous method for the production of indole derivatives - Google Patents
An analogous method for the production of indole derivativesInfo
- Publication number
- IS3994A IS3994A IS3994A IS3994A IS3994A IS 3994 A IS3994 A IS 3994A IS 3994 A IS3994 A IS 3994A IS 3994 A IS3994 A IS 3994A IS 3994 A IS3994 A IS 3994A
- Authority
- IS
- Iceland
- Prior art keywords
- production
- indole derivatives
- analogous method
- analogous
- indole
- Prior art date
Links
- 229940054051 antipsychotic indole derivative Drugs 0.000 title 1
- 150000002475 indoles Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Addiction (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929208492A GB9208492D0 (en) | 1992-04-16 | 1992-04-16 | Heterocyclic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IS3994A true IS3994A (en) | 1993-10-17 |
Family
ID=10714220
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IS3994A IS3994A (en) | 1992-04-16 | 1993-04-15 | An analogous method for the production of indole derivatives |
Country Status (41)
| Country | Link |
|---|---|
| US (4) | US5373018A (en) |
| EP (1) | EP0568136A1 (en) |
| JP (2) | JPH07505407A (en) |
| KR (1) | KR100264114B1 (en) |
| CN (1) | CN1042331C (en) |
| AP (1) | AP480A (en) |
| AT (1) | AT403917B (en) |
| AU (1) | AU666927B2 (en) |
| BE (1) | BE1006343A5 (en) |
| BG (1) | BG62136B1 (en) |
| BR (1) | BR1100323A (en) |
| CA (3) | CA2094076A1 (en) |
| CH (1) | CH685630A5 (en) |
| CY (1) | CY2038B1 (en) |
| CZ (1) | CZ285799B6 (en) |
| DK (1) | DK169890B1 (en) |
| ES (1) | ES2105924B1 (en) |
| FI (1) | FI106198B (en) |
| FR (1) | FR2690919B1 (en) |
| GB (2) | GB9208492D0 (en) |
| GE (1) | GEP19991704B (en) |
| GR (1) | GR1001619B (en) |
| HK (1) | HK95797A (en) |
| HU (2) | HU217964B (en) |
| IL (1) | IL105412A (en) |
| IS (1) | IS3994A (en) |
| IT (1) | IT1265325B1 (en) |
| LU (1) | LU88248A1 (en) |
| MX (1) | MX9302195A (en) |
| MY (1) | MY112232A (en) |
| NO (1) | NO301879B1 (en) |
| NZ (1) | NZ247413A (en) |
| OA (1) | OA10103A (en) |
| PL (1) | PL176451B1 (en) |
| RO (1) | RO113242B1 (en) |
| RU (1) | RU2129544C1 (en) |
| SE (1) | SE504336C2 (en) |
| SK (1) | SK281941B6 (en) |
| TW (1) | TW224457B (en) |
| WO (1) | WO1993021153A1 (en) |
| ZA (1) | ZA932642B (en) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9304500D0 (en) * | 1993-03-05 | 1993-04-21 | Glaxo Spa | Heterocyclic compounds |
| US5519048A (en) * | 1993-05-27 | 1996-05-21 | Merrell Pharmaceuticals Inc. | 3-(indol-3-yl)-propenoic acid derivatives and pharmaceutical compositions thereof |
| ES2103590T3 (en) * | 1993-05-27 | 1997-09-16 | Merrell Pharma Inc | DERIVATIVES OF ACID 3- (INDOL-3-IL) PROPENOIC USABLE AS ANTAGONISTS NMDA. |
| GB9319243D0 (en) * | 1993-09-17 | 1993-11-03 | Glaxo Spa | Heterocyclic compounds |
| GB9321221D0 (en) * | 1993-10-14 | 1993-12-01 | Glaxo Spa | Heterocyclic compounds |
| TW280819B (en) * | 1993-11-17 | 1996-07-11 | Sumitomo Pharma | |
| US5563157B1 (en) | 1994-10-31 | 1999-02-02 | Hoecst Marion Roussel Inc | Heterocycle substituted propenoic acid derivatives and pharmaceutical compositions thereof |
| GB9502695D0 (en) * | 1995-02-11 | 1995-03-29 | Glaxo Spa | Pharmaceutical composition |
| GB9504361D0 (en) * | 1995-03-04 | 1995-04-26 | Glaxo Spa | Heterocyclic compounds |
| WO1998011892A1 (en) * | 1996-09-17 | 1998-03-26 | The Regents Of The University Of California | Positive ampa receptor modulation to enhance brain neurotrophic factor expression |
| CN1139572C (en) * | 1996-09-30 | 2004-02-25 | 阿温蒂斯药物公司 | NMDA (N-methyl-D-aspartic acid) antagonists |
| US5922752A (en) * | 1997-06-11 | 1999-07-13 | Hoechst Marion Roussell, Inc. | NMDA (n-methyl-d-aspartate) antagonists |
| AU749623B2 (en) * | 1998-03-26 | 2002-06-27 | Astellas Pharma Inc. | Sustained release preparations |
| RU2277096C2 (en) * | 2000-07-31 | 2006-05-27 | ДАЙНИППОН СУМИТОМО ФАРМА Ко., ЛТД. | Agents against feeble-mindedness comprising derivatives of 2-aryl-8-oxodihydropurine as active component |
| US20030162825A1 (en) * | 2001-11-09 | 2003-08-28 | Sepracor Inc. | D-amino acid oxidase inhibitors for learning and memory |
| PL373484A1 (en) * | 2001-12-10 | 2005-09-05 | Amgen Inc. | Vanilloid receptor ligands and their use in treatments |
| PA8579701A1 (en) * | 2002-08-23 | 2005-05-24 | Pfizer Prod Inc | BETA-LACTAMASA INHIBITOR PROFARMACO |
| DE10306202A1 (en) * | 2003-02-13 | 2004-08-26 | Grünenthal GmbH | 2-(hetero)aryl-2-(N-((hetero)aryl)-amino)-acetic acid derivatives useful e.g. for treating anxiety, inflammation, allergy, depression, diarrhea or especially pain is NMDA antagonist |
| EP1636240A1 (en) * | 2003-06-05 | 2006-03-22 | Pfizer Products Inc. | Beta-lactamase inhibitor prodrug |
| RU2247563C1 (en) * | 2003-06-16 | 2005-03-10 | Пятигорская государственная фармацевтическая академия | Method for preparing solid medicinal formulation comprising glucosamine hydrochloride |
| ATE473967T1 (en) * | 2003-11-26 | 2010-07-15 | Pfizer Prod Inc | AMINOPYRAZOLE DERIVATIVES AS GSK-3 INHIBITORS |
| CA2551952A1 (en) * | 2003-12-29 | 2005-07-21 | Sepracor Inc. | Pyrrole and pyrazole daao inhibitors |
| RU2281755C2 (en) * | 2004-04-19 | 2006-08-20 | Пятигорская государственная фармацевтическая академия | Composition - medicinal formulation of anti-arthrosis agent, glucosamine hydrochloride, for rectal using |
| US20060002999A1 (en) * | 2004-06-17 | 2006-01-05 | Forest Laboratories, Inc. | Immediate release formulations of 1-aminocyclohexane compounds, memantine and neramexane |
| EP1904066B1 (en) | 2005-07-06 | 2018-05-23 | Sunovion Pharmaceuticals Inc. | COMBINATIONS OF ESZOPICLONE AND TRANS 4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-N-METHYL-1-NAPTHALENAMINE OR TRANS 4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-1-NAPTHALENAMINE, for treating MENOPAUSE, perimenopause AND COGNITIVE DISORDERS |
| CA2636324C (en) * | 2006-01-06 | 2012-03-20 | Sepracor Inc. | Cycloalkylamines as monoamine reuptake inhibitors |
| WO2007081542A2 (en) * | 2006-01-06 | 2007-07-19 | Sepracor Inc. | Tetralone-based monoamine reuptake inhibitors |
| DK2013835T3 (en) | 2006-03-31 | 2015-12-14 | Sunovion Pharmaceuticals Inc | Preparation of chiral amides and AMINES |
| US7579370B2 (en) * | 2006-06-30 | 2009-08-25 | Sepracor Inc. | Fused heterocycles |
| US7884124B2 (en) * | 2006-06-30 | 2011-02-08 | Sepracor Inc. | Fluoro-substituted inhibitors of D-amino acid oxidase |
| US20080082066A1 (en) * | 2006-10-02 | 2008-04-03 | Weyerhaeuser Co. | Crosslinked carboxyalkyl cellulose fibers having non-permanent and temporary crosslinks |
| EP1942104A1 (en) | 2006-12-20 | 2008-07-09 | sanofi-aventis | Heteroarylcyclopropanecarboxamides and their use as pharmaceuticals |
| US7902252B2 (en) * | 2007-01-18 | 2011-03-08 | Sepracor, Inc. | Inhibitors of D-amino acid oxidase |
| ZA200904686B (en) | 2007-01-18 | 2010-09-29 | Sepracor Inc | Inhibitiors of D-amino acid oxidase |
| RU2470011C2 (en) | 2007-05-31 | 2012-12-20 | Сепракор Инк. | Cycloalkylamines, containing phenyl as substituent, as inhibitors of monoamine reuptake |
| WO2009151498A2 (en) * | 2008-03-28 | 2009-12-17 | Forest Laboratories Holdings Limited | Memantine formulations |
| US20100120740A1 (en) * | 2008-08-07 | 2010-05-13 | Sepracor Inc. | Prodrugs of fused heterocyclic inhibitors of d-amino acid oxidase |
| US20110319463A1 (en) * | 2009-03-10 | 2011-12-29 | Saten Pharamaceuticals Co., Ltd. | Preventive or therapeutic agents for optic nerve disorders comprising 4,6-dichloro-1h-indole-2-carboxylic acid derivatives or salts thereof as active ingredients |
| US20110034434A1 (en) * | 2009-08-07 | 2011-02-10 | Sepracor Inc. | Prodrugs of fused heterocyclic inhibitors of d-amino acid oxidase |
| US9737531B2 (en) | 2012-07-12 | 2017-08-22 | Glytech, Llc | Composition and method for treatment of depression and psychosis in humans |
| AU2015253099B2 (en) | 2014-04-30 | 2019-07-18 | National Chiao Tung University | Use of known compounds as D-amino acid oxidase inhibitors |
| CN110234635B (en) | 2016-09-14 | 2023-03-10 | 宇凤·简·曾 | Novel substituted benzimidazole derivatives as D-amino acid oxidase (DAAO) inhibitors |
| AU2018284335A1 (en) | 2017-06-12 | 2020-01-30 | Glytech Llc. | Treatment of depression with NMDA antagonists and D2/5HT2A or selective 5HT2A antagonists |
| CN112707874A (en) * | 2020-12-29 | 2021-04-27 | 广东中科药物研究有限公司 | Antiviral compound and preparation method thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3010971A (en) * | 1960-08-04 | 1961-11-28 | Smith Kline French Lab | Cyclopropylamine derivatives and processes for their preparation |
| DK500285A (en) * | 1984-11-02 | 1986-05-03 | Glaxo Group Ltd | cephalosporin antibiotics |
| US4960786A (en) * | 1989-04-24 | 1990-10-02 | Merrell Dow Pharmaceuticals Inc. | Excitatory amino acid antagonists |
| JPH0347123A (en) * | 1989-05-05 | 1991-02-28 | G D Searle & Co | Therapeutic composition for cns disease con- taining indole-2-carboxylate compounds |
| DE69118539T2 (en) * | 1990-07-16 | 1996-09-19 | Merrell Dow Pharmaceuticals Inc., Cincinnati, Ohio | Excitatory amino acid antagonists |
| US5284862A (en) * | 1991-03-18 | 1994-02-08 | Warner-Lambert Company | Derivatives of 2-carboxyindoles having pharmaceutical activity |
| US5145845A (en) * | 1991-05-14 | 1992-09-08 | Warner-Lambert Co. | Substituted 2-carboxylindoles having pharmaceutical activity |
-
1992
- 1992-04-16 GB GB929208492A patent/GB9208492D0/en active Pending
-
1993
- 1993-04-14 ZA ZA932642A patent/ZA932642B/en unknown
- 1993-04-15 AU AU36923/93A patent/AU666927B2/en not_active Ceased
- 1993-04-15 US US08/046,947 patent/US5373018A/en not_active Expired - Fee Related
- 1993-04-15 JP JP5517997A patent/JPH07505407A/en active Pending
- 1993-04-15 CH CH1133/93A patent/CH685630A5/en not_active IP Right Cessation
- 1993-04-15 NZ NZ247413A patent/NZ247413A/en unknown
- 1993-04-15 MY MYPI93000690A patent/MY112232A/en unknown
- 1993-04-15 EP EP93201103A patent/EP0568136A1/en not_active Withdrawn
- 1993-04-15 IS IS3994A patent/IS3994A/en unknown
- 1993-04-15 CA CA002094076A patent/CA2094076A1/en not_active Abandoned
- 1993-04-15 SE SE9301241A patent/SE504336C2/en not_active IP Right Cessation
- 1993-04-15 RU RU94045915A patent/RU2129544C1/en active
- 1993-04-15 BE BE9300371A patent/BE1006343A5/en active
- 1993-04-15 CZ CZ942543A patent/CZ285799B6/en not_active IP Right Cessation
- 1993-04-15 US US08/047,430 patent/US5374649A/en not_active Expired - Fee Related
- 1993-04-15 PL PL93305554A patent/PL176451B1/en unknown
- 1993-04-15 SK SK1241-94A patent/SK281941B6/en unknown
- 1993-04-15 GR GR930100154A patent/GR1001619B/en not_active IP Right Cessation
- 1993-04-15 WO PCT/EP1993/000938 patent/WO1993021153A1/en not_active Ceased
- 1993-04-15 LU LU88248A patent/LU88248A1/en unknown
- 1993-04-15 FR FR9304452A patent/FR2690919B1/en not_active Expired - Fee Related
- 1993-04-15 JP JP5088844A patent/JPH0649027A/en active Pending
- 1993-04-15 IL IL105412A patent/IL105412A/en not_active IP Right Cessation
- 1993-04-15 KR KR1019940703668A patent/KR100264114B1/en not_active Expired - Fee Related
- 1993-04-15 DK DK043193A patent/DK169890B1/en active
- 1993-04-15 GB GB9307808A patent/GB2266091B/en not_active Expired - Fee Related
- 1993-04-15 CA CA002094075A patent/CA2094075A1/en not_active Abandoned
- 1993-04-15 AT AT0075293A patent/AT403917B/en not_active IP Right Cessation
- 1993-04-15 CA CA002094073A patent/CA2094073A1/en not_active Abandoned
- 1993-04-15 ES ES09300771A patent/ES2105924B1/en not_active Expired - Lifetime
- 1993-04-15 HU HU9402975A patent/HU217964B/en not_active IP Right Cessation
- 1993-04-15 IT IT93RM000236A patent/IT1265325B1/en active IP Right Grant
- 1993-04-15 MX MX9302195A patent/MX9302195A/en not_active IP Right Cessation
- 1993-04-15 US US08/047,429 patent/US5374648A/en not_active Expired - Fee Related
- 1993-04-15 CN CN93105797A patent/CN1042331C/en not_active Expired - Fee Related
- 1993-04-15 RO RO94-01658A patent/RO113242B1/en unknown
- 1993-04-16 AP APAP/P/1993/000524A patent/AP480A/en active
- 1993-04-16 GE GEAP19932602A patent/GEP19991704B/en unknown
- 1993-05-06 TW TW082103531A patent/TW224457B/zh active
-
1994
- 1994-10-10 OA OA60570A patent/OA10103A/en unknown
- 1994-10-12 FI FI944800A patent/FI106198B/en active
- 1994-10-14 NO NO943913A patent/NO301879B1/en not_active IP Right Cessation
- 1994-10-14 BG BG99111A patent/BG62136B1/en unknown
- 1994-12-08 US US08/351,762 patent/US5510367A/en not_active Expired - Fee Related
-
1995
- 1995-06-29 HU HU95P/P00538P patent/HU211826A9/en unknown
-
1997
- 1997-04-22 BR BR1100323-5A patent/BR1100323A/en active IP Right Grant
- 1997-06-26 HK HK95797A patent/HK95797A/en not_active IP Right Cessation
-
1998
- 1998-04-30 CY CY9802038A patent/CY2038B1/en unknown
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