IN2015KN00290A - - Google Patents
Info
- Publication number
- IN2015KN00290A IN2015KN00290A IN290KON2015A IN2015KN00290A IN 2015KN00290 A IN2015KN00290 A IN 2015KN00290A IN 290KON2015 A IN290KON2015 A IN 290KON2015A IN 2015KN00290 A IN2015KN00290 A IN 2015KN00290A
- Authority
- IN
- India
- Prior art keywords
- influenzae
- nthi
- antibody
- medicine
- treating
- Prior art date
Links
- 241000606768 Haemophilus influenzae Species 0.000 abstract 2
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940047650 haemophilus influenzae Drugs 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/285—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Virology (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Rheumatology (AREA)
- Otolaryngology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Urology & Nephrology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Ophthalmology & Optometry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0410866.8A GB0410866D0 (en) | 2004-05-14 | 2004-05-14 | Haemophilius influenzae |
| PCT/IB2005/001775 WO2005111066A2 (fr) | 2004-05-14 | 2005-05-16 | Polypeptides issus d'haemophilus influenzae non typable |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2015KN00290A true IN2015KN00290A (fr) | 2015-06-12 |
Family
ID=32527109
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN290KON2015 IN2015KN00290A (fr) | 2004-05-14 | 2005-05-16 |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US7749518B2 (fr) |
| EP (5) | EP2343313A1 (fr) |
| JP (2) | JP2008506364A (fr) |
| CN (1) | CN1997663A (fr) |
| BR (1) | BRPI0511118A (fr) |
| CA (1) | CA2566632A1 (fr) |
| GB (1) | GB0410866D0 (fr) |
| IN (1) | IN2015KN00290A (fr) |
| RU (1) | RU2432357C2 (fr) |
| WO (1) | WO2005111066A2 (fr) |
Families Citing this family (63)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60144353D1 (de) * | 2000-02-28 | 2011-05-12 | Novartis Vaccines & Diagnostic | Hybride Expression Neisserscher Proteine |
| HUE047780T2 (hu) * | 2002-10-11 | 2020-05-28 | Glaxosmithkline Biologicals Sa | Polipeptid vakcinák hipervirulens meningokokkusz vonalak elleni széles-spektrumú védelemre |
| WO2006138527A2 (fr) * | 2005-06-16 | 2006-12-28 | Children's Hospital, Inc. | Genes d'isolat d'otite moyenne de souche non typable haemophilus influenzae |
| GB0410866D0 (en) | 2004-05-14 | 2004-06-16 | Chiron Srl | Haemophilius influenzae |
| CA2602665A1 (fr) * | 2005-03-30 | 2006-10-19 | Novartis Vaccines And Diagnostics, Inc. | Haemophilus influenzae de type b |
| KR20080042865A (ko) | 2005-08-10 | 2008-05-15 | 아르네 포르스그렌 아베 | 모락셀라 카타랄리스와 상피세포, 세포외기질 단백질 및보체계의 상호작용 |
| JP5275814B2 (ja) * | 2006-01-17 | 2013-08-28 | フオルスレン,アルネ | 新規表面露出ヘモフィルス・インフルエンザ(HAEMOPHILUSINFLUENZAE)タンパク質(タンパク質E;pE) |
| US9132183B2 (en) * | 2007-03-09 | 2015-09-15 | Newport Laboratories | Modified live (JMSO strain) Haemophilus parasuis vaccine |
| US8647642B2 (en) | 2008-09-18 | 2014-02-11 | Aviex Technologies, Llc | Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment |
| EP2367568A2 (fr) * | 2008-12-17 | 2011-09-28 | Novartis AG | Vaccins méningococciques comprenant un récepteur de l'hémoglobine |
| EP2405938A2 (fr) * | 2009-02-13 | 2012-01-18 | Intercell AG | Antigenes haemphilus influenzae non typables |
| ITMI20090946A1 (it) | 2009-05-28 | 2010-11-29 | Novartis Ag | Espressione di proteine ricombinanti |
| PT3243526T (pt) | 2010-07-06 | 2020-03-04 | Glaxosmithkline Biologicals Sa | Distribuição de arn para despoletar múltiplas vias imunitárias |
| US9770463B2 (en) | 2010-07-06 | 2017-09-26 | Glaxosmithkline Biologicals Sa | Delivery of RNA to different cell types |
| PL2591114T3 (pl) | 2010-07-06 | 2017-08-31 | Glaxosmithkline Biologicals Sa | Immunizacja dużych ssaków małymi dawkami rna |
| AU2011276234B2 (en) | 2010-07-06 | 2016-02-25 | Glaxosmithkline Biologicals S.A. | Liposomes with lipids having an advantageous pKa- value for RNA delivery |
| FI4005592T3 (fi) | 2010-07-06 | 2023-01-13 | Virionin kaltaisia kuljetuspartikkeleita itsereplikoituville rna-molekyyleille | |
| AU2011295938B2 (en) | 2010-08-31 | 2016-01-14 | Glaxosmithkline Biologicals S.A. | Lipids suitable for liposomal delivery of protein-coding RNA |
| PT3981427T (pt) | 2010-08-31 | 2022-06-27 | Glaxosmithkline Biologicals Sa | Lipossomas peguilados para entrega de arn codificador de imunogénio |
| TR201903651T4 (tr) | 2010-10-11 | 2019-04-22 | Glaxosmithkline Biologicals Sa | Antijen uygulama platformları. |
| TW201302779A (zh) | 2011-04-13 | 2013-01-16 | Glaxosmithkline Biolog Sa | 融合蛋白質及組合疫苗 |
| KR20140066126A (ko) * | 2011-05-11 | 2014-05-30 | 리스벡 헬스케어 스웨덴 에이비 | 단백질 f - 라미닌 및 비트로넥틴 결합 특성을 갖는 신규한 헤모필러스 인플루엔자 부착분자 |
| EP2729165B1 (fr) | 2011-07-06 | 2017-11-08 | GlaxoSmithKline Biologicals SA | Compositions de combinaisons immunogènes et utilisations de celles-ci |
| CN103764121A (zh) | 2011-07-06 | 2014-04-30 | 诺华股份有限公司 | 用于递送rna分子的具有有用n:p比的脂质体 |
| BR112014004607A2 (pt) | 2011-08-31 | 2017-03-21 | Novartis Ag | lipossomas peguilados para entrega de rna codificado imunogênico |
| US10279026B2 (en) * | 2012-04-26 | 2019-05-07 | Glaxosmithkline Biologicals Sa | Antigens and antigen combinations |
| CN104321078A (zh) | 2012-04-26 | 2015-01-28 | 诺华股份有限公司 | 抗原和抗原组合 |
| EP3400960A1 (fr) | 2012-09-18 | 2018-11-14 | GlaxoSmithKline Biologicals S.A. | Vésicules de membrane externe |
| EA201891018A1 (ru) | 2013-03-08 | 2018-09-28 | Новартис Аг | Липиды и липидные композиции для доставки активных агентов |
| US11274144B2 (en) | 2013-06-13 | 2022-03-15 | Research Institute At Nationwide Children's Hospital | Compositions and methods for the removal of biofilms |
| US11248040B2 (en) | 2013-09-26 | 2022-02-15 | Trellis Bioscience, Llc | Binding moieties for biofilm remediation |
| EP4019506A1 (fr) | 2013-12-19 | 2022-06-29 | Novartis AG | Lipides et compositions lipidiques pour l'administration d'agents actifs |
| ES2774968T3 (es) | 2013-12-19 | 2020-07-23 | Novartis Ag | Lípidos y composiciones lipídicas para la administración de agentes activos |
| CN106794141B (zh) | 2014-07-16 | 2021-05-28 | 诺华股份有限公司 | 将核酸包封在脂质纳米粒主体中的方法 |
| CA2959322C (fr) * | 2014-08-27 | 2022-07-19 | Switchfloat Holdings Limited | Element tubulaire de type petrolier et manchon interne s'utilisant avec celui-ci, et procede de desactivation d'un clapet a flotteur a l'interieur de l'element tubulaire de type p etrolier |
| ES2969956T3 (es) | 2014-09-05 | 2024-05-23 | Novartis Ag | Lípidos y composiciones lipídicas para el suministro de agentes activos |
| EP3061826A1 (fr) | 2015-02-27 | 2016-08-31 | Novartis AG | Réplicons du flavivirus |
| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| WO2016200787A2 (fr) * | 2015-06-09 | 2016-12-15 | The Board Of Regents Of The University Of Oklahoma | Compositions et traitements pour haemophilus influenzae |
| EP3322408B1 (fr) | 2015-07-14 | 2022-06-08 | The Research Institute at Nationwide Children's Hospital | Nouvelle formulation pour l'élimination de pathogènes cariogènes et opportunistes dans la cavité buccale |
| WO2017023863A1 (fr) | 2015-07-31 | 2017-02-09 | Research Institute At Nationwide Children's Hospital | Peptides et anticorps pour l'élimination de biofilms |
| WO2017066719A2 (fr) | 2015-10-14 | 2017-04-20 | Research Institute At Nationwide Children's Hospital | Agents spécifiques interférant avec hu |
| JP2019522675A (ja) * | 2016-04-27 | 2019-08-15 | ▲拝▼西欧斯(北京)生物技▲術▼有限公司 | 興奮製神経毒性に関連した損傷の治療方法 |
| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| AU2018206552C1 (en) | 2017-01-04 | 2025-04-10 | Research Institute At Nationwide Children's Hospital | DNABII vaccines and antibodies with enhanced activity |
| WO2018129092A1 (fr) | 2017-01-04 | 2018-07-12 | Research Institute At Nationwide Children's Hospital | Fragments d'anticorps pour le traitement de troubles liés au biofilm |
| US20180221468A1 (en) * | 2017-01-19 | 2018-08-09 | Iowa State University Research Foundation, Inc. | Haemophilus influenzae immunogen |
| US11746136B2 (en) | 2017-03-15 | 2023-09-05 | Research Institute At Nationwide Children's Hospital | Composition and methods for disruption of bacterial biofilms without accompanying inflammation |
| EP3860718A4 (fr) | 2018-10-05 | 2022-08-31 | Research Institute at Nationwide Children's Hospital | Dérivés de protéine hmgb1 pour l'élimination de biofilms renvoyant à une demande connexe |
| EP3931206A1 (fr) * | 2019-02-27 | 2022-01-05 | Evaxion Biotech ApS | Vaccins ciblant h. influenzae |
| JP7627255B2 (ja) | 2019-07-08 | 2025-02-05 | リサーチ インスティチュート アット ネイションワイド チルドレンズ ホスピタル | バイオフィルムを破壊するための抗体組成物 |
| MX2022010406A (es) * | 2020-02-28 | 2022-11-09 | Trait Biosciences Inc | Sistemas, métodos y composiciones novedosas para la glucosilación de compuestos cannabinoides. |
| US12116614B2 (en) | 2020-06-30 | 2024-10-15 | Research Institute At Nationwide Children's Hospital | Methods for determining antibiotic sensitivity |
| BR112023006710A2 (pt) | 2020-10-14 | 2023-10-03 | George Mason Res Foundation Inc | Métodos de fabricação de nanopartícula lipídica e composições derivadas da mesma |
| CN115678869B (zh) * | 2021-07-28 | 2025-08-29 | 梅花(上海)生物科技有限公司 | 一株重组菌株及其生产氨基酸的方法 |
| EP4387597A1 (fr) | 2021-08-16 | 2024-06-26 | GlaxoSmithKline Biologicals SA | Lyophilisation de nanoparticules lipidiques (lnp) encapsulant de l'arn et leurs formulations |
| WO2023021421A1 (fr) | 2021-08-16 | 2023-02-23 | Glaxosmithkline Biologicals Sa | Vaccins à base d'arn lyophilisés à faible dose et leurs procédés de préparation et d'utilisation |
| CN114574456B (zh) * | 2022-03-18 | 2022-08-12 | 华南理工大学 | 一种亚硝酸盐还原酶突变体及其编码基因和应用 |
| GB202303019D0 (en) | 2023-03-01 | 2023-04-12 | Glaxosmithkline Biologicals Sa | Method of lyophilisation |
| CN116236575B (zh) * | 2023-03-07 | 2025-03-25 | 北京化工大学 | 一种光控偶联型纳米探针及其制备方法、光控偶联的纳米颗粒组合物与应用 |
| GB202311382D0 (en) | 2023-07-25 | 2023-09-06 | Glaxosmithkline Biologicals Sa | Lyophilised compostion |
| CN118388664B (zh) * | 2024-05-21 | 2024-12-03 | 广东省农业科学院动物卫生研究所 | 副猪嗜血杆菌融合抗原及其应用 |
Family Cites Families (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB234768A (en) * | 1924-05-28 | 1925-08-27 | Ritter Dental Mfg Company Inc | Improvements in adjustable brackets for supporting head-rests or other articles |
| SE8205892D0 (sv) | 1982-10-18 | 1982-10-18 | Bror Morein | Immunogent membranproteinkomplex, sett for framstellning och anvendning derav som immunstimulerande medel och sasom vaccin |
| US5916588A (en) | 1984-04-12 | 1999-06-29 | The Liposome Company, Inc. | Peptide-containing liposomes, immunogenic liposomes and methods of preparation and use |
| US6090406A (en) | 1984-04-12 | 2000-07-18 | The Liposome Company, Inc. | Potentiation of immune responses with liposomal adjuvants |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
| AU631377B2 (en) | 1988-08-25 | 1992-11-26 | Liposome Company, Inc., The | Affinity associated vaccine |
| DE3841091A1 (de) | 1988-12-07 | 1990-06-13 | Behringwerke Ag | Synthetische antigene, verfahren zu ihrer herstellung und ihre verwendung |
| ES2055785T3 (es) | 1989-01-17 | 1994-09-01 | Eniricerche Spa | Peptidos sinteticos y su uso como vehiculos universales para la preparacion de conjugados inmunogenos aptos para el desarrollo de vacunas sinteticas. |
| CA2017507C (fr) | 1989-05-25 | 1996-11-12 | Gary Van Nest | Adjuvant constitue d'une emulsion de gouttelettes submicron d'huile |
| FI920131A0 (fi) | 1989-07-14 | 1992-01-13 | Praxis Biolog Inc | Cytokin- och hormonbaerare foer konjugatvaccin. |
| IT1237764B (it) | 1989-11-10 | 1993-06-17 | Eniricerche Spa | Peptidi sintetici utili come carriers universali per la preparazione di coniugati immunogenici e loro impiego per lo sviluppo di vaccini sintetici. |
| DE69113564T2 (de) | 1990-08-13 | 1996-05-30 | American Cyanamid Co | Faser-Hemagglutinin von Bordetella pertussis als Träger für konjugierten Impfstoff. |
| IT1262896B (it) | 1992-03-06 | 1996-07-22 | Composti coniugati formati da proteine heat shock (hsp) e oligo-poli- saccaridi, loro uso per la produzione di vaccini. | |
| EP0671948B1 (fr) | 1992-06-25 | 1997-08-13 | SMITHKLINE BEECHAM BIOLOGICALS s.a. | Composition vaccinale contenant des adjuvants |
| IL102687A (en) | 1992-07-30 | 1997-06-10 | Yeda Res & Dev | Conjugates of poorly immunogenic antigens and synthetic pepide carriers and vaccines comprising them |
| ES2109685T5 (es) | 1993-03-23 | 2005-09-01 | Smithkline Beecham Biologicals S.A. | Composiciones para vacunas que contienen monofosforil-lipido a 3-o-desacilado. |
| DE69434839T2 (de) * | 1993-11-08 | 2007-10-25 | Sanofi Pasteur Ltd., Toronto | Transferrin-rezeptor-gene von haemophilus |
| GB9326174D0 (en) | 1993-12-22 | 1994-02-23 | Biocine Sclavo | Mucosal adjuvant |
| GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
| US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| US6429199B1 (en) | 1994-07-15 | 2002-08-06 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules for activating dendritic cells |
| US6239116B1 (en) | 1994-07-15 | 2001-05-29 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| US6245337B1 (en) * | 1994-08-25 | 2001-06-12 | Washington University | Haemophilus adherence and penetration proteins |
| AUPM873294A0 (en) | 1994-10-12 | 1994-11-03 | Csl Limited | Saponin preparations and use thereof in iscoms |
| UA56132C2 (uk) | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини |
| GB9513261D0 (en) | 1995-06-29 | 1995-09-06 | Smithkline Beecham Biolog | Vaccines |
| US5707829A (en) | 1995-08-11 | 1998-01-13 | Genetics Institute, Inc. | DNA sequences and secreted proteins encoded thereby |
| EP2172216A3 (fr) | 1997-03-10 | 2010-11-24 | Ottawa Hospital Research Institute | Utilisation d'acides nucléiques, comprenant des CPG-dinucléotides non-méthylés, comme adjuvant |
| US6818222B1 (en) | 1997-03-21 | 2004-11-16 | Chiron Corporation | Detoxified mutants of bacterial ADP-ribosylating toxins as parenteral adjuvants |
| GB9712347D0 (en) | 1997-06-14 | 1997-08-13 | Smithkline Beecham Biolog | Vaccine |
| GB9713156D0 (en) | 1997-06-20 | 1997-08-27 | Microbiological Res Authority | Vaccines |
| DE69838992T2 (de) | 1997-09-05 | 2008-12-24 | Glaxosmithkline Biologicals S.A., Rixensart | Öl-in-Wasser Emulsionen mit Saponinen |
| GB9725084D0 (en) | 1997-11-28 | 1998-01-28 | Medeva Europ Ltd | Vaccine compositions |
| WO1999040936A2 (fr) | 1998-02-12 | 1999-08-19 | American Cyanamid Company | Vaccins pneumococciques ou meningococciques formules avec l'interleukine-12 |
| US6303114B1 (en) | 1998-03-05 | 2001-10-16 | The Medical College Of Ohio | IL-12 enhancement of immune responses to T-independent antigens |
| WO1999052549A1 (fr) | 1998-04-09 | 1999-10-21 | Smithkline Beecham Biologicals S.A. | Compositions adjuvantes |
| US6562798B1 (en) | 1998-06-05 | 2003-05-13 | Dynavax Technologies Corp. | Immunostimulatory oligonucleotides with modified bases and methods of use thereof |
| GB9817052D0 (en) | 1998-08-05 | 1998-09-30 | Smithkline Beecham Biolog | Vaccine |
| DK1126876T3 (da) | 1998-10-16 | 2007-07-02 | Glaxosmithkline Biolog Sa | Adjuvanssystemer og vacciner |
| IL145043A0 (en) | 1999-03-19 | 2002-06-30 | Smithkline Beecham Biolog | Vaccine |
| JP2002541808A (ja) | 1999-04-09 | 2002-12-10 | テクラブ, インコーポレイテッド | ポリサッカリド結合体ワクチンのための組換えトキシンaタンパク質キャリア |
| EP1221971A2 (fr) | 1999-09-24 | 2002-07-17 | SmithKline Beecham Biologics SA | Utilisation d'une combinaison d'ester polyoxyethylenique de sorbitane et d'octoxynol comme adjuvant et son emploi dans les vaccins |
| CA2383110A1 (fr) | 1999-09-24 | 2001-03-29 | Veronique Henderickx | Adjuvant comprenant un ether ou ester d'alkyle polyethylene et au moins un tensioactif non ionique |
| US20010044416A1 (en) | 2000-01-20 | 2001-11-22 | Mccluskie Michael J. | Immunostimulatory nucleic acids for inducing a Th2 immune response |
| GB0007432D0 (en) | 2000-03-27 | 2000-05-17 | Microbiological Res Authority | Proteins for use as carriers in conjugate vaccines |
| CA2423487C (fr) | 2000-09-26 | 2015-12-15 | Hybridon, Inc. | Modulation de l'activite immunostimulatrice d'analogues oligonucleotidiques immunostimulateurs par des modifications chimiques de position |
| ES2435923T3 (es) | 2000-10-02 | 2013-12-26 | Id Biomedical Corporation Of Quebec | Antígenos de Haemophilus influenzae y los correspondientes fragmentos de ADN |
| GB0026002D0 (en) * | 2000-10-24 | 2000-12-13 | Smithkline Beecham Biolog | Novel compounds |
| IL154853A0 (en) | 2000-10-27 | 2003-10-31 | Chiron Spa | Nucleic acids and proteins from streptococcus groups a & b |
| GB0109289D0 (en) | 2001-04-12 | 2001-05-30 | Glaxosmithkline Biolog Sa | Novel compounds |
| GB0115176D0 (en) | 2001-06-20 | 2001-08-15 | Chiron Spa | Capular polysaccharide solubilisation and combination vaccines |
| AU2002330681C1 (en) | 2001-07-26 | 2015-04-02 | Glaxosmithkline Biologicals S.A. | Vaccines comprising aluminium adjuvants and histidine |
| EP2196217A1 (fr) | 2001-09-14 | 2010-06-16 | Cytos Biotechnology AG | Emballage de substances immunostimulantes dans des particules similaires aux virus: procédés de production et utilisations |
| CA2492823A1 (fr) | 2001-09-14 | 2003-03-27 | Martin F. Bachmann | Activation in vivo de cellules presentant un antigene en vue d'augmenter les reponses immunes induites par des particules de type virus |
| WO2003035836A2 (fr) | 2001-10-24 | 2003-05-01 | Hybridon Inc. | Modulation des proprietes immunostimulantes de composes a base d'oligonucleotides par presentation optimale d'extremites 5' |
| GB0200025D0 (en) * | 2002-01-02 | 2002-02-13 | Glaxosmithkline Biolog Sa | Novel compounds |
| WO2003076575A2 (fr) * | 2002-03-04 | 2003-09-18 | Fidelity Systems, Inc., Et Al. | Genome et sequence proteinique complets de methanopyrus kandleri av19 hyperthermophile, monophyletisme des archaea methanogenes, et methodes d'utilisation |
| US7241867B2 (en) * | 2003-03-06 | 2007-07-10 | Children's Hospital, Inc. | Polypeptide encoded by a nucleotide sequence of a nontypeable strain of Haemophilus influenzae genome |
| WO2006138527A2 (fr) | 2005-06-16 | 2006-12-28 | Children's Hospital, Inc. | Genes d'isolat d'otite moyenne de souche non typable haemophilus influenzae |
| GB0410866D0 (en) | 2004-05-14 | 2004-06-16 | Chiron Srl | Haemophilius influenzae |
| JP5275814B2 (ja) | 2006-01-17 | 2013-08-28 | フオルスレン,アルネ | 新規表面露出ヘモフィルス・インフルエンザ(HAEMOPHILUSINFLUENZAE)タンパク質(タンパク質E;pE) |
| AT507024B1 (de) | 2008-06-30 | 2011-10-15 | Coil Holding Gmbh | Drosselspule für elektrische energieversorgungsnetze mit reduzierten schallemissionen |
| US9018858B2 (en) | 2008-09-24 | 2015-04-28 | B/E Aerospace, Inc. | Calibration method for LED lighting systems |
-
2004
- 2004-05-14 GB GBGB0410866.8A patent/GB0410866D0/en not_active Ceased
-
2005
- 2005-05-16 RU RU2006144093/10A patent/RU2432357C2/ru not_active IP Right Cessation
- 2005-05-16 EP EP10194789A patent/EP2343313A1/fr not_active Withdrawn
- 2005-05-16 EP EP10190390A patent/EP2351774A1/fr not_active Withdrawn
- 2005-05-16 US US11/596,557 patent/US7749518B2/en not_active Expired - Fee Related
- 2005-05-16 JP JP2007512595A patent/JP2008506364A/ja not_active Withdrawn
- 2005-05-16 CA CA002566632A patent/CA2566632A1/fr not_active Abandoned
- 2005-05-16 EP EP05748150A patent/EP1745067A2/fr not_active Withdrawn
- 2005-05-16 EP EP10190386A patent/EP2341069A1/fr not_active Withdrawn
- 2005-05-16 EP EP10190381A patent/EP2351773A1/fr not_active Withdrawn
- 2005-05-16 WO PCT/IB2005/001775 patent/WO2005111066A2/fr not_active Ceased
- 2005-05-16 BR BRPI0511118-8A patent/BRPI0511118A/pt not_active Application Discontinuation
- 2005-05-16 CN CNA2005800238288A patent/CN1997663A/zh active Pending
- 2005-05-16 IN IN290KON2015 patent/IN2015KN00290A/en unknown
-
2010
- 2010-05-25 US US12/800,898 patent/US8124098B2/en not_active Expired - Fee Related
-
2011
- 2011-07-29 JP JP2011166505A patent/JP2012000112A/ja active Pending
-
2012
- 2012-01-24 US US13/357,394 patent/US20120148615A1/en not_active Abandoned
-
2014
- 2014-04-29 US US14/264,972 patent/US9102729B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20120148615A1 (en) | 2012-06-14 |
| WO2005111066A8 (fr) | 2007-05-18 |
| US9102729B2 (en) | 2015-08-11 |
| US20100303822A1 (en) | 2010-12-02 |
| EP1745067A2 (fr) | 2007-01-24 |
| EP2351773A1 (fr) | 2011-08-03 |
| GB0410866D0 (en) | 2004-06-16 |
| US20140234363A1 (en) | 2014-08-21 |
| WO2005111066A2 (fr) | 2005-11-24 |
| CN1997663A (zh) | 2007-07-11 |
| RU2006144093A (ru) | 2008-06-20 |
| CA2566632A1 (fr) | 2005-11-24 |
| WO2005111066A3 (fr) | 2006-05-26 |
| JP2008506364A (ja) | 2008-03-06 |
| US20080267966A1 (en) | 2008-10-30 |
| EP2343313A1 (fr) | 2011-07-13 |
| EP2351774A1 (fr) | 2011-08-03 |
| JP2012000112A (ja) | 2012-01-05 |
| EP2341069A1 (fr) | 2011-07-06 |
| US8124098B2 (en) | 2012-02-28 |
| RU2432357C2 (ru) | 2011-10-27 |
| US7749518B2 (en) | 2010-07-06 |
| BRPI0511118A (pt) | 2007-11-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IN2015KN00290A (fr) | ||
| NZ591415A (en) | Haemophilus influenzae type B | |
| MXPA02011656A (es) | Moleculas de acido nucleico nrg-2, polipeptidos, y metodos de diagnostico y terapeuticos. | |
| DK1645631T3 (da) | Neisseria antigener og præparater | |
| MY136095A (en) | Use of human anti-ctla-4 antibodies for treatment of cancer | |
| MXPA01011047A (es) | Secuencias genomicas de neisseria y metodos para su uso. | |
| NZ593289A (en) | Anti-neuropilin-1 antibodies for treating angiogenesis | |
| WO2004074455A3 (fr) | Variants de la region fc | |
| MXPA01003557A (es) | Secuencias genomicas de neisseria y metodos para su uso. | |
| UA84284C2 (ru) | Способы лечения, профилактики и диагностики инфекции helicobacter cerdo | |
| WO2002098355A3 (fr) | Methodes et compositions pour diagnostic et traitement de la resistance a l'insuline et des etats associes | |
| MXPA05011085A (es) | Composiciones y metodos relacionados a stop-1. | |
| EP2645106A3 (fr) | Procédés et produits pour évaluer une réponse immunitaire à un agent thérapeutique | |
| ATE521702T1 (de) | Krebsantigene und deren nutzung | |
| WO2004066933A3 (fr) | Compositions et methodes permettant de traiter le cancer au moyen de igsf9 et de liv-1 | |
| IL169804A (en) | 254p1d6b proteins, nucleic acids encoding the same, processes for producing the same, antibodies binding thereto and uses thereof | |
| EP1667634A4 (fr) | Vaccin contre l'anthrax | |
| ATE395356T1 (de) | Oberflächenprotein aus neisserien | |
| ATE313628T1 (de) | Klonierung und expression von haemophilus somnus transferrin-bindenden proteinen | |
| WO2004063226A3 (fr) | Nouveaux polypeptides de type fibrilline | |
| WO2007108903A3 (fr) | Vaccins contre campylobacter et procedes d'utilisation | |
| WO2004063225A3 (fr) | Nouveaux polypeptides de type fibuline | |
| BRPI0408023A (pt) | métodos para previnir gliconoilação de proteìnas | |
| WO2004031233A3 (fr) | Nouveaux polypeptides de type chimiokine | |
| BR0303226A (pt) | Proteìnas de aderência e penetração de haemophilus |