IN2014CN04700A - - Google Patents
Info
- Publication number
- IN2014CN04700A IN2014CN04700A IN4700CHN2014A IN2014CN04700A IN 2014CN04700 A IN2014CN04700 A IN 2014CN04700A IN 4700CHN2014 A IN4700CHN2014 A IN 4700CHN2014A IN 2014CN04700 A IN2014CN04700 A IN 2014CN04700A
- Authority
- IN
- India
- Prior art keywords
- chromosome
- mutations
- ptx
- copy
- prn
- Prior art date
Links
- 230000035772 mutation Effects 0.000 abstract 3
- 210000000349 chromosome Anatomy 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 101150006855 PRN gene Proteins 0.000 abstract 1
- 201000005702 Pertussis Diseases 0.000 abstract 1
- 210000003578 bacterial chromosome Anatomy 0.000 abstract 1
- 230000004077 genetic alteration Effects 0.000 abstract 1
- 231100000118 genetic alteration Toxicity 0.000 abstract 1
- 230000006801 homologous recombination Effects 0.000 abstract 1
- 238000002744 homologous recombination Methods 0.000 abstract 1
- 230000002779 inactivation Effects 0.000 abstract 1
- 230000037431 insertion Effects 0.000 abstract 1
- 238000003780 insertion Methods 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/235—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K2039/10—Brucella; Bordetella, e.g. Bordetella pertussis; Not used, see subgroups
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ZA201109417 | 2011-12-21 | ||
| PCT/TH2012/000052 WO2013141823A1 (en) | 2011-12-21 | 2012-12-20 | Modified bordetella pertussis strains |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014CN04700A true IN2014CN04700A (fi) | 2015-09-18 |
Family
ID=49223105
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN4700CHN2014 IN2014CN04700A (fi) | 2011-12-21 | 2012-12-20 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9187754B2 (fi) |
| EP (1) | EP2802646B1 (fi) |
| JP (1) | JP5966018B2 (fi) |
| KR (1) | KR101696986B1 (fi) |
| CN (1) | CN104024400B (fi) |
| BR (1) | BR112014014950B1 (fi) |
| ES (1) | ES2642138T3 (fi) |
| IN (1) | IN2014CN04700A (fi) |
| WO (1) | WO2013141823A1 (fi) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20190071706A1 (en) | 2016-04-04 | 2019-03-07 | University Of Virginia Patent Foundation | Compositions and methods for preventing and treating disease |
| WO2020011746A1 (en) | 2018-07-09 | 2020-01-16 | Dbv Technologies | Optimized epicutaneous vaccination |
| WO2020094580A1 (en) * | 2018-11-06 | 2020-05-14 | Glaxosmithkline Biologicals Sa | Immunogenic compositions |
| JP7517002B2 (ja) * | 2020-09-10 | 2024-07-17 | トヨタ自動車株式会社 | 形質転換体の製造方法及び形質転換方法 |
| CA3267059A1 (en) * | 2022-09-21 | 2024-03-28 | Prokarium Limited | SALMONELLA STRAIN WITH INTEGRATED LANDING PLATFORM AT THE CHROMOSOMAL LEVEL |
| CN118853525B (zh) * | 2024-09-26 | 2025-01-07 | 上海羽冠生物技术有限公司 | 经修饰的百日咳鲍特菌菌株 |
| CN120624499B (zh) * | 2025-08-15 | 2025-11-28 | 成都生物制品研究所有限责任公司 | 一种减毒的百日咳鲍特菌重组菌株及其构建方法和应用 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5221618A (en) | 1987-11-24 | 1993-06-22 | Connaught Laboratories Limited | Genetic detoxification of pertussis toxin |
| GB8727489D0 (en) | 1987-11-24 | 1987-12-23 | Connaught Lab | Detoxification of pertussis toxin |
| US5358868A (en) | 1987-11-24 | 1994-10-25 | Connaught Laboratories Limited | Genetic detoxification of pertussis toxin |
| US5244657A (en) | 1987-11-24 | 1993-09-14 | Connaught Laboratories Limited | Genetic detoxification of pertussis toxin |
| EP0396964B1 (en) | 1989-04-28 | 1995-09-06 | SCLAVO S.p.A. | Pertussis toxin mutants, bordetella strains capable of producing such mutants and their use in the development of antipertussis vaccines |
| US5786189A (en) * | 1989-11-29 | 1998-07-28 | Smithkline Beecham Biologicals (S.A.) | Vaccine |
| GB9115332D0 (en) | 1991-07-16 | 1991-08-28 | Connaught Lab | Manipulation of gene copy number in bordetella |
| EP0725653B2 (en) * | 1993-10-05 | 2008-04-02 | UCB Pharma Limited | Vaccine compositions |
| US20030072774A1 (en) * | 1994-06-10 | 2003-04-17 | Diane M. Gajewczyk | Proteinaceous adjuvants |
| GB9923060D0 (en) | 1999-09-29 | 1999-12-01 | Chiron Spa | Vaccine |
| US20050026866A1 (en) * | 2002-08-02 | 2005-02-03 | Pawelek John M. | Agents and methods for treatment of disease by oligosaccharide targeting agents |
| FI116068B (fi) * | 2003-09-15 | 2005-09-15 | Fit Biotech Oyj Plc | Uusi selektiojärjestelmä, siinä käyttökelpoinen vektori, bakteerisolukantoja sekä menetelmä solujen valikoimiseksi |
| WO2005090576A1 (ja) * | 2004-03-18 | 2005-09-29 | Japan Health Sciences Foundation | 百日咳感染症予防用dna構築物 |
| LT2432884T (lt) | 2009-05-22 | 2016-11-10 | Merial, Inc. | Neturinti antibiotiko plazmidė |
-
2012
- 2012-12-20 JP JP2014548741A patent/JP5966018B2/ja active Active
- 2012-12-20 IN IN4700CHN2014 patent/IN2014CN04700A/en unknown
- 2012-12-20 BR BR112014014950-0A patent/BR112014014950B1/pt active IP Right Grant
- 2012-12-20 KR KR1020147016949A patent/KR101696986B1/ko active Active
- 2012-12-20 CN CN201280064062.8A patent/CN104024400B/zh active Active
- 2012-12-20 WO PCT/TH2012/000052 patent/WO2013141823A1/en not_active Ceased
- 2012-12-20 EP EP12871942.4A patent/EP2802646B1/en not_active Revoked
- 2012-12-20 ES ES12871942.4T patent/ES2642138T3/es active Active
-
2014
- 2014-06-19 US US14/309,807 patent/US9187754B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP5966018B2 (ja) | 2016-08-10 |
| US20140302558A1 (en) | 2014-10-09 |
| JP2015502758A (ja) | 2015-01-29 |
| KR101696986B1 (ko) | 2017-01-17 |
| CN104024400A (zh) | 2014-09-03 |
| WO2013141823A1 (en) | 2013-09-26 |
| BR112014014950B1 (pt) | 2022-03-29 |
| KR20140107290A (ko) | 2014-09-04 |
| EP2802646A1 (en) | 2014-11-19 |
| EP2802646A4 (en) | 2015-08-12 |
| EP2802646B1 (en) | 2017-05-10 |
| BR112014014950A2 (pt) | 2020-06-30 |
| US9187754B2 (en) | 2015-11-17 |
| ES2642138T3 (es) | 2017-11-15 |
| CN104024400B (zh) | 2018-02-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IN2014CN04700A (fi) | ||
| BR112013033366A2 (pt) | regulação de genes de toxina e antitoxina para contenção biológica | |
| MX2016009243A (es) | Métodos de mutagénesis. | |
| PH12012501746A1 (en) | Polynucleotide molecules for gene regulation in plants | |
| CY1117367T1 (el) | Αντινοηματικο νουκλεϊνικο οξυ | |
| MX2014012364A (es) | Composiciones para controlar acaros varroa en abejas. | |
| UA111193C2 (uk) | Застосування n-(тетразол-4-іл)- або n-(триазол-3-іл)арилкарбоксамідів або їх солей для контролю небажаних рослин на площах трансгенних культур, що толерантні до гербіцидів, що є інгібіторами hppd | |
| TW201217533A (en) | Genomics of actinoplanes utahensis | |
| Wang et al. | IS 5 inserts upstream of the master motility operon flhDC in a quasi-Lamarckian way | |
| MY171760A (en) | Microorganisms and methods for the production of caprolactone | |
| IN2014KN01374A (fi) | ||
| MY166780A (en) | Genetic manipulation and expression system for pucciniomycotina and ustilaginomycotina subphyla | |
| MX369867B (es) | Gen y variaciones asociadas con el fenotipo bm1, marcadores moleculares, y su uso. | |
| MX2010002304A (es) | Metodos para incorporar multiples genes en una planta de cultivo. | |
| UA115235C2 (uk) | Ген токсину axmi335 bacillus thuringiensis та спосіб його застосування | |
| MX2015006958A (es) | Autofijacion de nitrogeno en plantas imitando las vias procarioticas. | |
| Kolatka et al. | Replication and partitioning of the broad-host-range plasmid RK2 | |
| WO2014152607A3 (en) | Dosage compensating transgenes and cells | |
| WO2013030176A3 (en) | Live attenuated influenza virus | |
| MX2013004044A (es) | Composiciones de pared de celula de acido ribonucleico bacterial y metodos para hacerlas y usarlas. | |
| Han et al. | Complete genome sequence of carotenoid-producing Microbacterium sp. strain PAMC28756 isolated from an Antarctic lichen | |
| BR112015010138A2 (pt) | engenharia bacteriana | |
| IN2014CN03414A (fi) | ||
| Oh et al. | Complete genome sequence of Hymenobacter sp. strain PAMC26554, an ionizing radiation-resistant bacterium isolated from an Antarctic lichen | |
| CO6761394A2 (es) | Microorganismos resistentes a especies reactivas de oxigeno |