[go: up one dir, main page]

IN2014CH01141A - - Google Patents

Download PDF

Info

Publication number
IN2014CH01141A
IN2014CH01141A IN1141CH2014A IN2014CH01141A IN 2014CH01141 A IN2014CH01141 A IN 2014CH01141A IN 1141CH2014 A IN1141CH2014 A IN 1141CH2014A IN 2014CH01141 A IN2014CH01141 A IN 2014CH01141A
Authority
IN
India
Prior art keywords
glucitol
anhydro
ethoxyphenyl
chloro
phenyl
Prior art date
Application number
Inventor
Thirumalai Rajan Srinivasan
Eswaraiah Sajja
Raghuram Suraparaju
Original Assignee
Msn Lab Private Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Msn Lab Private Ltd filed Critical Msn Lab Private Ltd
Priority to IN1141CH2014 priority Critical patent/IN2014CH01141A/en
Priority to EP15758707.2A priority patent/EP3114115A4/en
Priority to PCT/IN2015/000119 priority patent/WO2015132803A2/en
Priority to US15/303,577 priority patent/US20170029398A1/en
Publication of IN2014CH01141A publication Critical patent/IN2014CH01141A/en
Priority to US16/202,840 priority patent/US20190144411A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to a process for the preparation of (lS)-l,5-anhydro-l-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol which is represented by the following structural formula-1 and its glycerol solvate.
IN1141CH2014 2014-03-06 2015-03-06 IN2014CH01141A (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
IN1141CH2014 IN2014CH01141A (en) 2014-03-06 2015-03-06
EP15758707.2A EP3114115A4 (en) 2014-03-06 2015-03-06 Process for the preparation of (1s)-1,5-anhydro-1-c-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-d-glucitol and its solvate thereof
PCT/IN2015/000119 WO2015132803A2 (en) 2014-03-06 2015-03-06 Process for the preparation of (1s)-1,5-anhydro-1-c-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-d-glucitol and its solvate thereof
US15/303,577 US20170029398A1 (en) 2014-03-06 2015-03-06 Process for the preparation of (1s)-1,5-anhydro-1-c-{4-chloro-3-4[(4-ethoxyphenyl)methyl]phenyl]-glucitol and its solvate thereof
US16/202,840 US20190144411A1 (en) 2014-03-06 2018-11-28 Process for the preparation of (1S)-1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl) methyl]phenyl]-D-glucitol and its solvate thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN1141CH2014 IN2014CH01141A (en) 2014-03-06 2015-03-06

Publications (1)

Publication Number Publication Date
IN2014CH01141A true IN2014CH01141A (en) 2015-09-11

Family

ID=54055961

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1141CH2014 IN2014CH01141A (en) 2014-03-06 2015-03-06

Country Status (4)

Country Link
US (2) US20170029398A1 (en)
EP (1) EP3114115A4 (en)
IN (1) IN2014CH01141A (en)
WO (1) WO2015132803A2 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106316803B (en) * 2015-06-19 2019-07-09 重庆博腾制药科技股份有限公司 A kind of synthetic method of SGLT-2 inhibitor intermediate
WO2017046730A1 (en) 2015-09-15 2017-03-23 Laurus Labs Private Limited Co-crystals of sglt2 inhibitors, process for their preparation and pharmaceutical compositions thereof
US9845303B2 (en) 2015-10-19 2017-12-19 Cadila Healthcare Limited Process for the preparation of dapagliflozin
US10913762B2 (en) 2016-01-27 2021-02-09 Msn Laboratories Private Limited Process for the preparation of D-glucitol, 1,5-anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl] oxy]phenyl] methyl] phenyl]-, (1S) and its crystalline forms thereof
WO2017221211A1 (en) * 2016-06-24 2017-12-28 Biocon Limited Process for the preparation of dapagliflozin and its solvate thereof
CN107641139A (en) * 2016-07-22 2018-01-30 江苏豪森药业集团有限公司 Crystal formation of Dapagliflozin intermediate and preparation method thereof
CN108610316B (en) * 2016-12-09 2021-11-05 江苏豪森药业集团有限公司 Preparation method of dapagliflozin
WO2018142422A1 (en) * 2017-02-02 2018-08-09 Indoco Remedies Limited Process for the preparation of dapagliflozin
CN107417515A (en) * 2017-03-30 2017-12-01 上海常丰生物医药科技有限公司 A kind of new method for synthesizing Dapagliflozin intermediate
CN109705075B (en) * 2018-12-13 2022-12-23 苏中药业集团股份有限公司 Purification method of dapagliflozin
CN110396040B (en) * 2019-09-09 2020-12-15 东南大学 A kind of method of one-pot synthesis of diaryl methyl ketal
EP4114365A1 (en) 2020-03-05 2023-01-11 KRKA, d.d., Novo mesto Pharmaceutical composition comprising sglt2 inhibitor
WO2021245253A1 (en) 2020-06-05 2021-12-09 Krka, D.D., Novo Mesto Preparation of highly pure amorphous dapagliflozin
CN111748004A (en) * 2020-06-30 2020-10-09 药璞(上海)医药科技有限公司 Crystal form of high-purity dapagliflozin intermediate and preparation method thereof
CN112500267A (en) 2020-12-04 2021-03-16 江苏慧聚药业有限公司 Preparation of 4-bromo-2- (4' -ethoxy-benzyl) -1-chlorobenzene
CN113880796A (en) * 2021-10-14 2022-01-04 山东诚创蓝海医药科技有限公司 Preparation method of dapagliflozin

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH12000002657B1 (en) * 1999-10-12 2006-02-21 Bristol Myers Squibb Co C-aryl glucoside SGLT2 inhibitors
US6515117B2 (en) 1999-10-12 2003-02-04 Bristol-Myers Squibb Company C-aryl glucoside SGLT2 inhibitors and method
JP2006516257A (en) * 2003-01-03 2006-06-29 ブリストル−マイヤーズ　スクイブ　カンパニー Method for producing C-aryl glucoside SGLT2 inhibitor
US7919598B2 (en) * 2006-06-28 2011-04-05 Bristol-Myers Squibb Company Crystal structures of SGLT2 inhibitors and processes for preparing same
KR101604119B1 (en) * 2011-06-14 2016-03-16 주식회사 녹십자 Novel c-aryl ansa sglt2 inhibitors
EP2773359A4 (en) * 2011-10-31 2015-10-21 Scinopharm Taiwan Ltd Crystalline and non-crystalline forms of sglt2 inhibitors
WO2015104658A2 (en) * 2014-01-08 2015-07-16 Dr. Reddy’S Laboratories Limited Amorphous solid dispersion of dapagliflozin and process for the preparation of amorphous dapagliflozin

Also Published As

Publication number Publication date
EP3114115A4 (en) 2017-08-23
EP3114115A2 (en) 2017-01-11
US20190144411A1 (en) 2019-05-16
US20170029398A1 (en) 2017-02-02
WO2015132803A2 (en) 2015-09-11
WO2015132803A3 (en) 2016-01-14

Similar Documents

Publication Publication Date Title
IN2014CH01141A (en)
PH12017500408B1 (en) Heteroaryl compounds as btk inhibitors and uses thereof
LT3230278T (en) NEW METHYLPIPERIDINE COMPOUNDS USEFUL FOR INSULATION OF MICROSOMAL PROSTAGLANDIN E2 SYNTHASE-1
EP3209653A4 (en) Process for the preparation of (r,s)-nicotine
IN2014CH00247A (en)
EA201691649A1 (en) METHOD OF OBTAINING ANTI-FIBER CONNECTIONS
EP3137074A4 (en) Prostaglandin receptor ep2 antagonists, derivatives, compositions, and uses related thereto
EA201691648A1 (en) METHOD OF OBTAINING ANTI-FIBER CONNECTIONS
EP3102554A4 (en) Conversion of 2,3-butanediol to butadiene
IL250038A0 (en) 4,5-dihydroisoxazole derivatives as nampt inhibitors
CL2017000152A1 (en) Isoindolinone derivatives
EA201790982A1 (en) SYNTHESIS OF KOPANLISIB AND ITS DIHYDROCHLORIDE
MX2016015464A (en) Oral pharmaceutical composition of isotretinoin.
HK1249046A1 (en) Methods of treating hepatitis b virus
NZ729087A (en) Azetidinyloxyphenylpyrrolidine compounds
CL2017000151A1 (en) Pyridone derivatives
HK1221645A1 (en) Benzoquinolone inhibitors of vmat2
IN2014MU01192A (en)
MX2017001331A (en) Oral pharmaceutical composition of isotretinoin.
MX2016015465A (en) Oral pharmaceutical composition of isotretinoin.
IN2014MU00195A (en)
IN2014CH00304A (en)
EP3102540A4 (en) Compositions including a vacancy-engineered (ve)-zno nanocomposite, methods of making a composition, methods of using a composition
EA201692246A1 (en) Method of producing 2,6-dimethylbenzoquinone
EP3116774A4 (en) Thermal insulating bushing for piston first stages