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IN2014MU00814A - - Google Patents

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Publication number
IN2014MU00814A
IN2014MU00814A IN814MU2014A IN2014MU00814A IN 2014MU00814 A IN2014MU00814 A IN 2014MU00814A IN 814MU2014 A IN814MU2014 A IN 814MU2014A IN 2014MU00814 A IN2014MU00814 A IN 2014MU00814A
Authority
IN
India
Prior art keywords
stem cells
cancer stem
compositions
methods
proliferation
Prior art date
Application number
Inventor
Srivastava Sangeeta
Athavale Maithili
Shukre Kedar
More Gayatri
Original Assignee
Godavari Biorefineries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Godavari Biorefineries Ltd filed Critical Godavari Biorefineries Ltd
Priority to PCT/IN2015/050019 priority Critical patent/WO2015136556A2/en
Priority to AU2015228385A priority patent/AU2015228385A1/en
Priority to IN814MU2014 priority patent/IN2014MU00814A/en
Priority to MX2016011730A priority patent/MX2016011730A/en
Priority to US15/124,588 priority patent/US20170022215A1/en
Priority to CA2940807A priority patent/CA2940807A1/en
Priority to EP15761463.7A priority patent/EP3116882A4/en
Priority to JP2016556295A priority patent/JP2017507163A/en
Publication of IN2014MU00814A publication Critical patent/IN2014MU00814A/en
Priority to IL247720A priority patent/IL247720A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

ABSTRACT The present invention provides compounds of formula (I), compositions, uses thereof and methods for eradicating or inhibiting proliferation of cancer stem cells which includes killing; and/or inducing apoptosis in cancer stem cells. Included within the scope of such compounds, compositions, uses thereof and methods are those in which proliferation of cancer stem cells are selectively eradicated or inhibited. I
IN814MU2014 2014-03-11 2015-03-11 IN2014MU00814A (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
PCT/IN2015/050019 WO2015136556A2 (en) 2014-03-11 2015-03-11 Compounds for eradicating or inhibiting proliferation of cancer stem cells
AU2015228385A AU2015228385A1 (en) 2014-03-11 2015-03-11 Compounds for eradicating or inhibiting proliferation of cancer stem cells
IN814MU2014 IN2014MU00814A (en) 2014-03-11 2015-03-11
MX2016011730A MX2016011730A (en) 2014-03-11 2015-03-11 Compounds for eradicating or inhibiting proliferation of cancer stem cells.
US15/124,588 US20170022215A1 (en) 2014-03-11 2015-03-11 Compounds for Eradicating or Inhibiting Proliferation of Cancer Stem Cells
CA2940807A CA2940807A1 (en) 2014-03-11 2015-03-11 Compounds for eradicating or inhibiting proliferation of cancer stem cells
EP15761463.7A EP3116882A4 (en) 2014-03-11 2015-03-11 Compounds for eradicating or inhibiting proliferation of cancer stem cells
JP2016556295A JP2017507163A (en) 2014-03-11 2015-03-11 Compounds for eradication or growth inhibition of cancer stem cells
IL247720A IL247720A0 (en) 2014-03-11 2016-09-08 Compounds for eradicating or inhibiting proliferation of cancer stem cells

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN814MU2014 IN2014MU00814A (en) 2014-03-11 2015-03-11

Publications (1)

Publication Number Publication Date
IN2014MU00814A true IN2014MU00814A (en) 2015-09-25

Family

ID=54072549

Family Applications (1)

Application Number Title Priority Date Filing Date
IN814MU2014 IN2014MU00814A (en) 2014-03-11 2015-03-11

Country Status (9)

Country Link
US (1) US20170022215A1 (en)
EP (1) EP3116882A4 (en)
JP (1) JP2017507163A (en)
AU (1) AU2015228385A1 (en)
CA (1) CA2940807A1 (en)
IL (1) IL247720A0 (en)
IN (1) IN2014MU00814A (en)
MX (1) MX2016011730A (en)
WO (1) WO2015136556A2 (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD248593A1 (en) * 1985-01-11 1987-08-12 Univ Halle Wittenberg PROCESS FOR PREPARING 4-BASED SUBSTITUTED THIENO / 2,3-D / PYRIMIDIN-6-YLCARBOXYANESEESTERS
EP1675861B1 (en) * 2003-08-29 2015-12-23 Vernalis (R&D) Ltd. Pyrimidothiophene compounds
US8138356B2 (en) * 2007-10-16 2012-03-20 Angiogeney, Inc. Chemical inhibitors of inhibitors of differentiation

Also Published As

Publication number Publication date
EP3116882A4 (en) 2017-08-02
WO2015136556A3 (en) 2016-01-14
US20170022215A1 (en) 2017-01-26
CA2940807A1 (en) 2015-09-17
WO2015136556A2 (en) 2015-09-17
IL247720A0 (en) 2016-11-30
EP3116882A2 (en) 2017-01-18
MX2016011730A (en) 2016-12-14
JP2017507163A (en) 2017-03-16
AU2015228385A1 (en) 2016-09-15

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