[go: up one dir, main page]

IN2012DN03418A - - Google Patents

Download PDF

Info

Publication number
IN2012DN03418A
IN2012DN03418A IN3418DEN2012A IN2012DN03418A IN 2012DN03418 A IN2012DN03418 A IN 2012DN03418A IN 3418DEN2012 A IN3418DEN2012 A IN 3418DEN2012A IN 2012DN03418 A IN2012DN03418 A IN 2012DN03418A
Authority
IN
India
Prior art keywords
induces
immunogenic composition
whole
response
primarily antibody
Prior art date
Application number
Other languages
English (en)
Inventor
Richard Malley
Porter Anderson
Yingjie Lu
George A Robertson
Mark Alderson
Jean-Francois Lucien Maisonneuve
Andrea Maria Tate
Oliverira Dias Waldely De
Goncalves Viviane Maimoni
Original Assignee
Childrens Medical Center
Path Vaccine Solutions
Fundacao Butantan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Childrens Medical Center, Path Vaccine Solutions, Fundacao Butantan filed Critical Childrens Medical Center
Publication of IN2012DN03418A publication Critical patent/IN2012DN03418A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/09Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092Streptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/521Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/543Mucosal route intranasal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55544Bacterial toxins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IN3418DEN2012 2009-10-09 2010-10-12 IN2012DN03418A (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25034809P 2009-10-09 2009-10-09
US38042910P 2010-09-07 2010-09-07
PCT/US2010/052298 WO2011044576A2 (fr) 2009-10-09 2010-10-12 Vaccin à cellules entières à dissociation sélective

Publications (1)

Publication Number Publication Date
IN2012DN03418A true IN2012DN03418A (fr) 2015-10-23

Family

ID=43857436

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3418DEN2012 IN2012DN03418A (fr) 2009-10-09 2010-10-12

Country Status (5)

Country Link
US (1) US9827299B2 (fr)
EP (1) EP2485764A4 (fr)
CN (1) CN102648003B (fr)
IN (1) IN2012DN03418A (fr)
WO (1) WO2011044576A2 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011112906A2 (fr) 2010-03-12 2011-09-15 Children's Medical Center Corporation Nouveaux immunogènes et procédés pour la découverte et le dépistage de ceux-ci
JPWO2012157699A1 (ja) * 2011-05-18 2014-07-31 味の素株式会社 動物用免疫賦活剤、それを含む飼料及びその製造方法
WO2014124228A1 (fr) 2013-02-07 2014-08-14 Children's Medical Center Corporation Antigènes de protéine qui confèrent une protection contre une colonisation et/ou une maladie pneumococcique
JP2021535921A (ja) 2018-09-12 2021-12-23 アフィニバックス、インコーポレイテッド 多価肺炎球菌ワクチン
EP4164684A4 (fr) * 2020-06-12 2024-11-20 Schossau, Tom M. Inactivation du génome enveloppé dans des particules ou des enveloppes sphériques ou pléomorphes de coronavirus pour former un vaccin
WO2023039223A1 (fr) 2021-09-09 2023-03-16 Affinivax, Inc. Vaccins antipneumococciques multivalents
CN117756959B (zh) * 2024-02-22 2024-05-14 北京民海生物科技有限公司 一种肺炎链球菌荚膜多糖的制备方法

Family Cites Families (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL6612233A (fr) * 1966-08-30 1968-03-01
NL7012832A (fr) * 1970-08-29 1972-03-02
US3852420A (en) * 1971-01-20 1974-12-03 Richardson Merrell Inc Equine strangles vaccine and method of preparing and using the same
FR2174745A1 (en) * 1972-03-09 1973-10-19 Inst Elevage Med Vet Mixed veterinary vaccine - active against symptomatic and bacterial anthrax
US3920811A (en) * 1972-12-22 1975-11-18 Cutter Lab Adjuvant compositions
US4675176A (en) 1983-12-12 1987-06-23 Norden Laboratories Moraxella bovis protease vaccine
US5281392A (en) * 1986-03-10 1994-01-25 Rubinstein Alan I Method for disinfecting red blood cells, blood products, and corneas
DE3715840A1 (de) * 1987-05-12 1988-12-01 Boehringer Mannheim Gmbh Fuer ein lytisch wirksames, chimaeres protein kodierende rekombinante dna und ihre verwendung
GB8906795D0 (en) * 1989-03-23 1989-05-10 Carroll Noel Method of preparing vaccines
ES2075221T3 (es) * 1989-10-06 1995-10-01 Janos Szabo Proceso para la preparacion de una composicion farmaceutica para el tratamiento de las enfermedades de la piel, especialmente las dermatitis piogenas y atopicas.
US5418130A (en) 1990-04-16 1995-05-23 Cryopharm Corporation Method of inactivation of viral and bacterial blood contaminants
ES2084057T3 (es) 1990-06-07 1996-05-01 Bayer Ag Bacterina para el tratamiento de enfermedades causadas por f. necrophorum y procedimiento para su produccion.
US6042838A (en) 1991-02-15 2000-03-28 Uab Research Foundation immunogenic compositions for mucosal administration of pneumococcal surface protein A (PspA)
AU4114893A (en) * 1992-04-27 1993-11-29 Michigan State University Method for producing a bacterial vaccine and novel vaccines produced thereby
US6764682B1 (en) * 1994-06-16 2004-07-20 Aventis Pasteur Limited Adjuvant compositions containing more than one adjuvant
AUPN175495A0 (en) * 1995-03-14 1995-04-13 University Of New England, The Method and composition for the prevention of the over production of acid
US6743430B1 (en) * 1995-03-29 2004-06-01 Richard E. Parizek Multicomponent vaccine containing clostridial and non-clostridial organisms in a low dose
DE19603649A1 (de) * 1996-02-01 1997-08-07 Werner Lubitz Rekombinante Expression von S-Layer-Proteinen
WO1998018931A2 (fr) * 1996-10-31 1998-05-07 Human Genome Sciences, Inc. Polynucleotides et sequences de streptococcus pneumoniae
IT1296148B1 (it) * 1996-11-22 1999-06-09 Renata Maria Anna Ve Cavaliere Uso di batteri lattici per accrescere il livello delle ceramidi della pelle e delle mucose, e composizioni dermatologiche e cosmetiche atte
US6416959B1 (en) * 1997-02-27 2002-07-09 Kenneth Giuliano System for cell-based screening
US6800744B1 (en) * 1997-07-02 2004-10-05 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics
US5958414A (en) 1997-09-03 1999-09-28 Heska Corporation Composition to protect a mammal against Bartonella henselae infection
BR9812976A (pt) 1997-10-20 2000-08-08 Bayer Ag Vacina de neospora
US7172762B1 (en) 1999-01-29 2007-02-06 Pfizer Inc. Erysipelothrix rhusiopathiae antigens and vaccine compositions
CA2390613A1 (fr) 1999-11-08 2001-05-17 Biomune Vaccins contre mycoplasma bovis et leurs procedes d'utilisation
DE10003241A1 (de) * 2000-01-26 2001-08-02 Werner Lubitz Verschließen von Bakterienghosts
US6378677B1 (en) * 2000-10-03 2002-04-30 Honda Giken Kogyo Kabushiki Kaisha Power transmission device having electromagnetic clutch
JP2006512401A (ja) * 2001-06-05 2006-04-13 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン ナノエマルジョンワクチン
AU2002314626B2 (en) * 2001-06-11 2008-01-03 Applied Nanosystems B.V. Methods for binding AcmA-type protein anchor fusions to cell-wall material of micro-organisms
US7399476B2 (en) 2001-07-11 2008-07-15 Werner Lubitz Nucleic acid free ghost preparations
CN102172406B (zh) * 2001-10-15 2013-03-13 恩吉尼克分子传递私人有限公司 用作体外和体内dna转染与基因治疗载体的完整微细胞
US20060121058A1 (en) * 2002-08-08 2006-06-08 Children's Medical Center Corporation Anti-pneumococcal preparations
EP1618884A1 (fr) * 2003-04-28 2006-01-25 Sekisui Chemical Co., Ltd. Instrument d'induction de cytokine et procede d'induction correspondant
US7204993B2 (en) * 2004-03-18 2007-04-17 The United States Of America As Represented By The Secretary Of Agriculture Streptococcus agalactiae vaccine
US7211428B1 (en) * 2004-05-18 2007-05-01 Council Of Scientific And Industrial Research Strain of Bacillus as a bioinoculant
US7291276B1 (en) * 2004-06-21 2007-11-06 Winston Company, Inc. Controlled production and release of oxygen activated biocide into holding tanks for RV's, boats and the like
US20060003454A1 (en) * 2004-07-02 2006-01-05 Conjugon, Inc. Non-dividing donor cells for gene transfer
ATE526978T1 (de) 2004-08-17 2011-10-15 Hunter Immunology Ltd Verfahren zur herstellung von oral abgetöteten vakzinen
AU2005316041B2 (en) * 2004-12-14 2010-06-24 Alk Abello A/S Pharmaceutical composition comprising a bacterial cell displaying a heterologous proteinaceous compound
WO2006107097A1 (fr) * 2005-04-01 2006-10-12 Riken Vaccin nasal
EP2371843B1 (fr) * 2005-05-19 2014-09-17 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services Épitopes fonctionnels d'antigène psa A de streptococcus pneumoniae et leurs utilisations
EP1746103A1 (fr) * 2005-07-20 2007-01-24 Applied NanoSystems B.V. Ancres de proteine bifonctionelle
ES2423663T3 (es) * 2005-08-08 2013-09-23 Oregon Health And Science University Inactivación de patógenos con peróxido de hidrógeno para la producción de vacunas
CN101365480B (zh) 2005-11-01 2014-11-05 诺华疫苗和诊断有限两合公司 经由β-丙内酯处理的残留细胞DNA水平降低的细胞衍生病毒疫苗
US20110172826A1 (en) * 2005-12-14 2011-07-14 Amodei Dario G Device including altered microorganisms, and methods and systems of use
WO2008008092A2 (fr) * 2006-07-10 2008-01-17 The Arizona Board Of Regents On Behalf Of The University Of Arizona Protéine de pilus campylobacter, compositions et procédés
JP5249326B2 (ja) * 2007-07-23 2013-07-31 ワクチン リサーチ インターナショナル ピーエルシー 不活化ブドウ球菌全細胞ワクチン
JP5722782B2 (ja) * 2008-09-26 2015-05-27 ナノバイオ コーポレーション ナノエマルジョン治療用組成物及びその使用方法
TW201043242A (en) * 2009-03-26 2010-12-16 Intervet Int Bv Vaccine for protection against Streptococcus suis bacteria of various serotypes
US8551749B2 (en) * 2009-04-23 2013-10-08 The Invention Science Fund I, Llc Device including bone cage and method for treatment of disease in a subject
US8668911B2 (en) * 2009-05-14 2014-03-11 The Regents Of The University Of Michigan Streptococcus vaccine compositions and methods of using the same
CN107213461B (zh) * 2009-09-10 2022-03-15 勃林格殷格翰动物保健美国公司 包含含有皂苷的佐剂的新疫苗制剂
JP2013512692A (ja) * 2009-12-07 2013-04-18 シナプティック リサーチ,リミテッド ライアビリティ カンパニー プロテアーゼ活性阻害剤の同定とプロテアーゼ活性の存在を測定するための方法

Also Published As

Publication number Publication date
WO2011044576A2 (fr) 2011-04-14
US9827299B2 (en) 2017-11-28
CN102648003B (zh) 2016-01-13
EP2485764A4 (fr) 2014-01-29
EP2485764A2 (fr) 2012-08-15
US20120251577A1 (en) 2012-10-04
CN102648003A (zh) 2012-08-22
WO2011044576A3 (fr) 2011-08-18

Similar Documents

Publication Publication Date Title
IL273607A (en) Humanized antibodies against liv-1, preparations containing them and their uses
IN2012DN03418A (fr)
PH12013500810B1 (en) Anti-il-23 antibodies
WO2013063613A3 (fr) Procédés et compositions associés à la neutralisation intracellulaire par une igg
AU2016204319A1 (en) Methods and compositions for producing squalene using yeast
PH12013501942A1 (en) Antibody-drug conjugates
WO2010145792A8 (fr) Protéines bispécifiques se liant à un antigène
MX336682B (es) Anticuerpos contra csf-1r humanos y usos de los mismos.
EP3038644A4 (fr) Procédés de conjugaison d'anticorps régiospécifiques et compositions
TW201129381A (en) Antibodies against human CSF-1R and uses thereof
AU2011217848A8 (en) Integrin aVB8 neutralizing antibody
WO2009135181A3 (fr) Procédé et compositions pour préparer des anticorps et des dérivés d'anticorps avec une fucosylation centrale réduite
MY171841A (en) Antibody formulation
WO2012032181A3 (fr) Nouveaux dérivés d'anticorps
PH12012501157A1 (en) Anti-her3 antibodies and uses thereof
MX2012000396A (es) Metodos y composiciones para uso en tartamientos celulares.
MY170720A (en) Antibody formulations
MX356337B (es) Anticuerpos contra csf-1r humano y sus usos.
UA104459C2 (uk) Антитіла проти fgfr3 і способи їх застосування
AU2010233994A8 (en) Bispecific anti-ErbB-3/anti-c-Met antibodies
IL219801A (en) Anti-a4 antibody. 4c isolates, vectors encoded by them, methods of preparation, preparations containing them and their use
MX2011011512A (es) Proteinas de union de factor h quimericas (fhbp) y metodos de uso.
MX2013012184A (es) Composiciones formadoras de gel in situ.
MX2014005372A (es) Molecula portadora que comprende un antigeno spr0096 y un spr2021.
WO2012121746A3 (fr) Imagerie de la masse des cellules bêta