IN2012DN02117A - - Google Patents
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- Publication number
- IN2012DN02117A IN2012DN02117A IN2117DEN2012A IN2012DN02117A IN 2012DN02117 A IN2012DN02117 A IN 2012DN02117A IN 2117DEN2012 A IN2117DEN2012 A IN 2117DEN2012A IN 2012DN02117 A IN2012DN02117 A IN 2012DN02117A
- Authority
- IN
- India
Links
Classifications
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
- A01K67/0276—Knock-out vertebrates
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
- A01K67/0278—Knock-in vertebrates, e.g. humanised vertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
- A61K35/39—Pancreas; Islets of Langerhans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/01—Hexosyltransferases (2.4.1)
- C12Y204/01087—N-Acetyllactosaminide 3-alpha-galactosyltransferase (2.4.1.87), i.e. alpha-1,3-galactosyltransferase
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
- A01K2217/052—Animals comprising random inserted nucleic acids (transgenic) inducing gain of function
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/15—Animals comprising multiple alterations of the genome, by transgenesis or homologous recombination, e.g. obtained by cross-breeding
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/20—Animal model comprising regulated expression system
- A01K2217/206—Animal model comprising tissue-specific expression system, e.g. tissue specific expression of transgene, of Cre recombinase
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/108—Swine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/02—Animal zootechnically ameliorated
- A01K2267/025—Animal producing cells or organs for transplantation
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/035—Animal model for multifactorial diseases
- A01K2267/0362—Animal model for lipid/glucose metabolism, e.g. obesity, type-2 diabetes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/40—Vector systems having a special element relevant for transcription being an insulator
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Environmental Sciences (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Developmental Biology & Embryology (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23415009P | 2009-08-14 | 2009-08-14 | |
| PCT/US2010/045665 WO2011020120A2 (en) | 2009-08-14 | 2010-08-16 | Multi-transgenic pigs for diabetes treatment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2012DN02117A true IN2012DN02117A (en) | 2015-08-21 |
Family
ID=43586899
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2117DEN2012 IN2012DN02117A (en) | 2009-08-14 | 2012-03-09 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US9339519B2 (en) |
| EP (1) | EP2464219B1 (en) |
| JP (3) | JP2013501528A (en) |
| KR (3) | KR102122267B1 (en) |
| CN (2) | CN102548394A (en) |
| AU (3) | AU2010282239A1 (en) |
| CA (2) | CA3104704A1 (en) |
| ES (1) | ES2767881T3 (en) |
| IN (1) | IN2012DN02117A (en) |
| NZ (1) | NZ794410A (en) |
| WO (1) | WO2011020120A2 (en) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2617930A1 (en) | 2005-08-09 | 2007-03-29 | Revivicor, Inc. | Transgenic ungulates expressing ctla4-ig and uses thereof |
| US9420770B2 (en) | 2009-12-01 | 2016-08-23 | Indiana University Research & Technology Corporation | Methods of modulating thrombocytopenia and modified transgenic pigs |
| PT2709445T (en) * | 2011-05-16 | 2018-11-27 | Univ Missouri | Porcine reproductive and respiratory syndrome virus resistant animals |
| WO2013063076A1 (en) * | 2011-10-25 | 2013-05-02 | Indiana University Research & Technology Corporation | Compositions for and methods of modulating complications, risks and issues with xenotransplantation |
| US20140112958A1 (en) * | 2012-10-24 | 2014-04-24 | Mwm Biomodels Gmbh | Pancreatic islets of transgenic LEA29Y animals for treating diabetes |
| US20140115728A1 (en) | 2012-10-24 | 2014-04-24 | A. Joseph Tector | Double knockout (gt/cmah-ko) pigs, organs and tissues |
| US20150139994A1 (en) * | 2013-11-12 | 2015-05-21 | The Regents Of The University Of California | Compositions and methods for preventing allogeneic immune rejection |
| CN103675291A (en) * | 2013-11-25 | 2014-03-26 | 南昌大学 | Method for screening wheat varieties with low celiac sprue toxicity based on T cell epitopes |
| EP3604498A1 (en) * | 2014-04-11 | 2020-02-05 | Université catholique de Louvain | Transgenic pig islets and uses thereof for treating diabetes |
| AU2015360502A1 (en) * | 2014-12-10 | 2017-06-29 | Regents Of The University Of Minnesota | Genetically modified cells, tissues, and organs for treating disease |
| SG10202103445QA (en) * | 2015-04-13 | 2021-05-28 | Regeneron Pharma | Humanized sirpa-il15 knockin mice and methods of use thereof |
| ES2784360T3 (en) | 2015-05-29 | 2020-09-24 | Regeneron Pharma | Nonhuman animals that have a disruption at a C9ORF72 locus |
| IL300476B2 (en) * | 2015-06-30 | 2024-07-01 | Eiger Group Int Inc | Use of chloroquine and calamizole compounds to treat inflammatory and cancerous conditions |
| BR112018002417A2 (en) | 2015-08-06 | 2018-09-18 | Univ Missouri | non-human animal or descendant thereof or an animal cell, swine animal, descendant or cell, cell, descendant, reproduction method, animal population, method for increasing an animal resistance, nucleic acid molecule, nucleic acid and nucleic acid isolated |
| CN108473963A (en) * | 2015-09-09 | 2018-08-31 | 雷维维科公司 | Multiple transgenic pigs for xenotransplantation |
| JP6617495B2 (en) * | 2015-09-18 | 2019-12-11 | 東ソー株式会社 | Method for detecting tumor cells |
| US11214789B2 (en) | 2016-05-03 | 2022-01-04 | Flodesign Sonics, Inc. | Concentration and washing of particles with acoustics |
| KR20230110373A (en) * | 2016-06-14 | 2023-07-21 | 리전츠 오브 더 유니버스티 오브 미네소타 | Genetically modified cells, tissues, and organs for treating disease |
| US10781453B2 (en) * | 2016-09-30 | 2020-09-22 | Regeneron Pharmaceuticals, Inc. | Non-human animals having a hexanucleotide repeat expansion in a C9ORF72 locus |
| JP7146777B2 (en) * | 2016-10-07 | 2022-10-04 | セカルナ・ファーマシューティカルズ・ゲーエムベーハー・ウント・コ・カーゲー | Immunosuppressive reversion oligonucleotides that inhibit CD39 expression |
| KR101960414B1 (en) * | 2016-11-11 | 2019-03-27 | 대한민국 | Transgenic cloned porcine Models for diabetes disease using human DPP-4 and the use thereof |
| US12058986B2 (en) | 2017-04-20 | 2024-08-13 | Egenesis, Inc. | Method for generating a genetically modified pig with inactivated porcine endogenous retrovirus (PERV) elements |
| EP3685661A4 (en) | 2017-09-19 | 2021-05-19 | Meiji University | ORGAN DEVELOPMENT PROCESS WITHOUT A SPECIFIC FUNCTIONAL CELL |
| KR101833225B1 (en) | 2017-09-26 | 2018-03-02 | 주식회사 엠젠플러스 | Transgenic cloned piglet expressing human proinsulin and producing method thereof |
| US11160260B2 (en) | 2018-04-17 | 2021-11-02 | The Curators Of The University Of Missouri | Methods for protecting porcine fetuses from infection with porcine reproductive and respiratory syndrome virus (PRRSV) |
| US10799614B2 (en) | 2018-10-05 | 2020-10-13 | Xenotherapeutics, Inc. | Xenotransplantation products and methods |
| US10883084B2 (en) | 2018-10-05 | 2021-01-05 | Xenotherapeutics, Inc. | Personalized cells, tissues, and organs for transplantation from a humanized, bespoke, designated-pathogen free, (non-human) donor and methods and products relating to same |
| US12331320B2 (en) | 2018-10-10 | 2025-06-17 | The Research Foundation For The State University Of New York | Genome edited cancer cell vaccines |
| KR20210105914A (en) | 2018-12-20 | 2021-08-27 | 리제너론 파마슈티칼스 인코포레이티드 | Nuclease-mediated repeat expansion |
| WO2020228039A1 (en) * | 2019-05-16 | 2020-11-19 | Egenesis, Inc. | Cells, tissues, organs, and/or animals having one or more modified genes for enhanced xenograft survival and/or tolerance |
| MX2021013914A (en) * | 2019-05-16 | 2022-04-06 | Egenesis Inc | CELLS, TISSUES, ORGANS AND/OR ANIMALS THAT HAVE ONE OR MORE GENES MODIFIED FOR IMPROVED XENOGRAFT SURVIVAL AND/OR TOLERANCE. |
| WO2021072777A1 (en) * | 2019-10-18 | 2021-04-22 | Egenesis, Inc. | Cells, tissues, organs, and/or animals having one or more modified genes for enhanced xenograft survival and/or tolerance |
| WO2020228043A1 (en) * | 2019-05-16 | 2020-11-19 | Egenesis, Inc. | Cells, tissues, organs, and/or animals having one or more modified genes for enhanced xenograft survival and/or tolerance |
| WO2021072778A1 (en) * | 2019-10-18 | 2021-04-22 | Egenesis, Inc. | Cells, tissues, organs, and/or animals having one or more modified genes for enhanced xenograft survival and/or tolerance |
| TW202140778A (en) * | 2020-01-07 | 2021-11-01 | 美商Ｅ開創生物技術股份有限公司 | Methods and compositions for production of xenogeneic islet cells and treatment of insulin-resistant or -deficient conditions with the same |
| CN113429475A (en) * | 2020-03-23 | 2021-09-24 | 成都中科奥格生物科技有限公司 | Glue raw material and preparation method and application thereof |
| AU2021292671A1 (en) * | 2020-06-17 | 2022-12-22 | Otsuka Pharmaceutical Factory, Inc. | Encapsulated pancreatic islet |
| CN111955422A (en) * | 2020-08-21 | 2020-11-20 | 五邑大学 | Construction method of donor pig for xenotransplantation |
| IL302830A (en) * | 2020-11-13 | 2023-07-01 | Egenesis Inc | Cells, tissues, organs, and animals having one or more modified genes for enhanced xenograft survival and tolerance |
| CN113016721A (en) * | 2021-03-29 | 2021-06-25 | 何冬凌 | Preparation and application of Chinese cobra-biting pig model |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6482404B1 (en) | 1989-10-12 | 2002-11-19 | David James White | Transplantation of tissue comprising a DNA sequence encoding a homologous complement restriction factor |
| CN1122719C (en) | 1989-10-12 | 2003-10-01 | 艾姆特兰有限公司 | Modified biological material |
| US5859307A (en) | 1992-02-04 | 1999-01-12 | Massachusetts Institute Of Technology | Mutant RAG-1 deficient animals having no mature B and T lymphocytes |
| US5578314A (en) | 1992-05-29 | 1996-11-26 | The Regents Of The University Of California | Multiple layer alginate coatings of biological tissue for transplantation |
| WO1994021799A1 (en) | 1993-03-16 | 1994-09-29 | Austin Research Institute | USE OF PORCINE GAL α(1,3) GALACTOSYL TRANSFERASE IN XENOGRAFT THERAPIES |
| WO1995020661A1 (en) | 1994-01-27 | 1995-08-03 | Bresatec Ltd. | Materials and methods for management of hyperacute rejection in human xenotransplantation |
| DE69535752D1 (en) | 1994-04-13 | 2008-06-26 | Biotransplant Inc | ALPHA (1,3) GALACTOSYL TRANSFERASE NEGATIVE PIG |
| US6235969B1 (en) * | 1997-01-10 | 2001-05-22 | University Of Massachusetts | Cloning pigs using donor nuclei from non-quiescent differentiated cells |
| ES2513043T3 (en) | 1997-03-26 | 2014-10-24 | Imperial Innovations Limited | Cell membrane anchored anticoagulant fusion protein |
| GB9809280D0 (en) | 1998-04-30 | 1998-07-01 | Rpms Technology Ltd | Immunosupression |
| US20020012660A1 (en) | 1999-03-04 | 2002-01-31 | Alan Colman | Method of preparing a somatic cells for nuclear transfer |
| US6303355B1 (en) | 1999-03-22 | 2001-10-16 | Duke University | Method of culturing, cryopreserving and encapsulating pancreatic islet cells |
| CA2361646A1 (en) | 1999-10-22 | 2001-05-03 | Alexion Pharmaceuticals, Inc. | An engineered recombinant molecule that regulates humoral and cellular effector functions of the immune system |
| EP1248640B1 (en) | 2000-01-20 | 2006-10-04 | Diabcell Pty Limited | Preparation and xenotransplantation of porcine islets |
| ATE390931T1 (en) | 2001-05-23 | 2008-04-15 | Bristol Myers Squibb Co | METHOD FOR PROTECTING AN ALLOGENIC ISLAND TRANSPLANT WITH SOLUBLE CTLA4 MUTATION MOLECULES |
| AU2002364596A1 (en) | 2001-12-21 | 2003-07-15 | Immerge Biotherapeutics, Inc. | Knockout swine and methods for making the same |
| US7547522B2 (en) | 2002-08-14 | 2009-06-16 | Immerge Biotherapeutics, Inc. | Method to enrich for α(1,3)-galactosyltransferase null pig cells |
| EP1534819B1 (en) | 2002-08-21 | 2009-12-09 | Revivicor, Inc. | Porcine animals lacking any expression of functional alpha 1,3 galactosyltransferase |
| WO2005053512A2 (en) | 2003-11-26 | 2005-06-16 | Dana-Farber Cancer Institute, Inc. | Animal models of pancreatic adenocarcinoma and uses therefor |
| CN1953657A (en) * | 2004-03-17 | 2007-04-25 | 雷维维科公司 | Tissue products derived from animals lacking expression of any functional α1,3-galactosyltransferase |
| CA2857051A1 (en) * | 2004-03-17 | 2005-09-29 | David Ayares | Tissue products derived from animals lacking any expression of functional alpha 1,3 galactosyltransferase |
| US7378569B2 (en) | 2004-06-01 | 2008-05-27 | Animal Technology Institute Taiwan | Transgenic pigs carrying both hHO-1 and hDAF transgenes for xenotransplantation |
| CA2617930A1 (en) | 2005-08-09 | 2007-03-29 | Revivicor, Inc. | Transgenic ungulates expressing ctla4-ig and uses thereof |
| DK2348827T3 (en) | 2008-10-27 | 2015-07-20 | Revivicor Inc | IMMUNICIPLY COMPROMATED PETS |
-
2010
- 2010-08-16 AU AU2010282239A patent/AU2010282239A1/en not_active Abandoned
- 2010-08-16 CN CN2010800457799A patent/CN102548394A/en active Pending
- 2010-08-16 CN CN201310552545.9A patent/CN103891675B/en active Active
- 2010-08-16 CA CA3104704A patent/CA3104704A1/en active Pending
- 2010-08-16 KR KR1020197015948A patent/KR102122267B1/en active Active
- 2010-08-16 KR KR1020127006683A patent/KR20120050485A/en not_active Ceased
- 2010-08-16 US US12/857,514 patent/US9339519B2/en active Active
- 2010-08-16 JP JP2012524939A patent/JP2013501528A/en not_active Withdrawn
- 2010-08-16 WO PCT/US2010/045665 patent/WO2011020120A2/en not_active Ceased
- 2010-08-16 EP EP10808879.0A patent/EP2464219B1/en active Active
- 2010-08-16 ES ES10808879T patent/ES2767881T3/en active Active
- 2010-08-16 CA CA2771299A patent/CA2771299C/en active Active
- 2010-08-16 NZ NZ794410A patent/NZ794410A/en unknown
- 2010-08-16 KR KR1020187009415A patent/KR20180036810A/en not_active Ceased
-
2012
- 2012-03-09 IN IN2117DEN2012 patent/IN2012DN02117A/en unknown
-
2016
- 2016-03-11 JP JP2016047895A patent/JP6525905B2/en active Active
- 2016-05-05 US US15/147,228 patent/US10383317B2/en active Active
- 2016-06-16 AU AU2016204067A patent/AU2016204067B2/en active Active
-
2018
- 2018-05-14 AU AU2018203351A patent/AU2018203351B2/en active Active
- 2018-05-17 JP JP2018095246A patent/JP2018121663A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2018203351B2 (en) | 2020-03-26 |
| WO2011020120A2 (en) | 2011-02-17 |
| CN102548394A (en) | 2012-07-04 |
| AU2016204067A1 (en) | 2016-07-07 |
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