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IN2012CH05359A - - Google Patents

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Publication number
IN2012CH05359A
IN2012CH05359A IN5359CH2012A IN2012CH05359A IN 2012CH05359 A IN2012CH05359 A IN 2012CH05359A IN 5359CH2012 A IN5359CH2012 A IN 5359CH2012A IN 2012CH05359 A IN2012CH05359 A IN 2012CH05359A
Authority
IN
India
Prior art keywords
relates
diphenoxylate hydrochloride
diphenylbutanenitrile
phenylpiperidine
carboxylate
Prior art date
Application number
Inventor
S Iyengar Dr D
Saikia Dr Anil
M Niranjan T
Original Assignee
Hygro Chemicals Pharmtek Pvt Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hygro Chemicals Pharmtek Pvt Ltd filed Critical Hygro Chemicals Pharmtek Pvt Ltd
Priority to IN5359CH2012 priority Critical patent/IN2012CH05359A/en
Publication of IN2012CH05359A publication Critical patent/IN2012CH05359A/en

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Abstract

The present invention relates to an improved process for the preparation of diphenoxylate hydrochloride of the formula (I) by condensing 4-Bromo-2,2-diphenylbutanenitrile ( II) and Ethyl 4-phenylpiperidine-4-carboxylate (III) in aqueous medium under basic conditions in the presence of a catalyst. This invention also relates to an improved method for purification of the diphenoxylate hydrochloride.
IN5359CH2012 2012-12-22 2012-12-22 IN2012CH05359A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IN5359CH2012 IN2012CH05359A (en) 2012-12-22 2012-12-22

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN5359CH2012 IN2012CH05359A (en) 2012-12-22 2012-12-22

Publications (1)

Publication Number Publication Date
IN2012CH05359A true IN2012CH05359A (en) 2015-08-14

Family

ID=54397776

Family Applications (1)

Application Number Title Priority Date Filing Date
IN5359CH2012 IN2012CH05359A (en) 2012-12-22 2012-12-22

Country Status (1)

Country Link
IN (1) IN2012CH05359A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107586275A (en) * 2017-06-01 2018-01-16 合肥远志医药科技开发有限公司 A kind of diphenoxylate hydrochloride industrialized preparing process

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107586275A (en) * 2017-06-01 2018-01-16 合肥远志医药科技开发有限公司 A kind of diphenoxylate hydrochloride industrialized preparing process

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