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IN2012MN02924A - - Google Patents

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Publication number
IN2012MN02924A
IN2012MN02924A IN2924MUN2012A IN2012MN02924A IN 2012MN02924 A IN2012MN02924 A IN 2012MN02924A IN 2924MUN2012 A IN2924MUN2012 A IN 2924MUN2012A IN 2012MN02924 A IN2012MN02924 A IN 2012MN02924A
Authority
IN
India
Application number
Inventor
Zhipei Wu
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IN2012MN02924A publication Critical patent/IN2012MN02924A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • A61K31/5025Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IN2924MUN2012 2010-07-30 2012-12-31 IN2012MN02924A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36933510P 2010-07-30 2010-07-30
PCT/US2011/044926 WO2012015677A1 (en) 2010-07-30 2011-07-22 6- (1-methyl-1h-pyrazol-4-yl)-3-(2-methyl-2h-indazol-5-

Publications (1)

Publication Number Publication Date
IN2012MN02924A true IN2012MN02924A (en) 2015-06-12

Family

ID=44513148

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2924MUN2012 IN2012MN02924A (en) 2010-07-30 2012-12-31

Country Status (15)

Country Link
US (1) US8268836B2 (en)
EP (1) EP2598144B1 (en)
JP (1) JP5738412B2 (en)
KR (1) KR20130052740A (en)
CN (1) CN103002898A (en)
AR (1) AR085183A1 (en)
AU (1) AU2011282973B2 (en)
BR (1) BR112013002211A2 (en)
CA (1) CA2805494A1 (en)
EA (1) EA201270818A1 (en)
ES (1) ES2516940T3 (en)
IN (1) IN2012MN02924A (en)
MX (1) MX2013001247A (en)
TW (1) TWI431008B (en)
WO (1) WO2012015677A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6129956B2 (en) * 2012-05-09 2017-05-17 イーライ リリー アンド カンパニー Anti-c-Met antibody
CN103122000B (en) 2012-09-03 2013-12-25 中美冠科生物技术(太仓)有限公司 High-selectivity c-Met kinase inhibitor used as antitumor drug
TWI667233B (en) 2013-12-19 2019-08-01 德商拜耳製藥公司 Novel indazolecarboxamides, processes for their preparation, pharmaceutical preparations comprising them and their use for producing medicaments
US10386376B2 (en) 2015-11-09 2019-08-20 Jeimei, Llc Sample container with integrated test strip
CN106924260B (en) * 2015-12-31 2018-05-25 北京浦润奥生物科技有限责任公司 Application of compound in preparation of medicine for treating brain glioma
KR20210142154A (en) 2019-03-21 2021-11-24 옹쎄오 DBAIT molecules in combination with kinase inhibitors for the treatment of cancer
CN114761006A (en) 2019-11-08 2022-07-15 Inserm(法国国家健康医学研究院) Methods of treating cancer resistant to kinase inhibitors
WO2021148581A1 (en) 2020-01-22 2021-07-29 Onxeo Novel dbait molecule and its use
AU2024241633A1 (en) 2023-03-30 2025-11-06 Revolution Medicines, Inc. Compositions for inducing ras gtp hydrolysis and uses thereof
WO2024229406A1 (en) 2023-05-04 2024-11-07 Revolution Medicines, Inc. Combination therapy for a ras related disease or disorder
WO2025034702A1 (en) 2023-08-07 2025-02-13 Revolution Medicines, Inc. Rmc-6291 for use in the treatment of ras protein-related disease or disorder
TW202530228A (en) 2023-10-12 2025-08-01 美商銳新醫藥公司 Ras inhibitors
WO2025171296A1 (en) 2024-02-09 2025-08-14 Revolution Medicines, Inc. Ras inhibitors
WO2025240847A1 (en) 2024-05-17 2025-11-20 Revolution Medicines, Inc. Ras inhibitors
WO2025255438A1 (en) 2024-06-07 2025-12-11 Revolution Medicines, Inc. Methods of treating a ras protein-related disease or disorder

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2008007049A (en) * 2005-11-30 2008-10-23 Vertex Pharma Inhibitors of c-met and uses thereof.
PE20121506A1 (en) * 2006-07-14 2012-11-26 Amgen Inc TRIAZOLOPYRIDINE COMPOUNDS AS C-MET INHIBITORS
US8217177B2 (en) 2006-07-14 2012-07-10 Amgen Inc. Fused heterocyclic derivatives and methods of use
PL2081937T3 (en) 2006-10-23 2013-01-31 Sgx Pharmaceuticals Inc Triazolopyridazine protein kinase modulators
KR20090071612A (en) * 2006-10-23 2009-07-01 에스지엑스 파마슈티컬스, 인코포레이티드 Bicyclic Triazoles as Protein Kinase Modulators
SI2081937T1 (en) * 2006-10-23 2012-11-30 Sgx Pharmaceuticals Inc Triazolopyridazine protein kinase modulators
PA8792501A1 (en) * 2007-08-09 2009-04-23 Sanofi Aventis NEW DERIVATIVES OF 6-TRIAZOLOPIRIDACINA-SULFANIL BENZOTIAZOL AND BENCIMIDAZOL, ITS PREPARATION PROCEDURE, ITS APPLICATION AS MEDICATIONS, PHARMACEUTICAL COMPOSITIONS AND NEW MAIN USE AS MET INHIBITORS.
UY31676A1 (en) 2008-02-28 2009-09-30 "DERIVATIVES OF 3-METHYL-IMIDIAZO- [1,2-B] -PIRIDAZINA"

Also Published As

Publication number Publication date
AR085183A1 (en) 2013-09-18
EP2598144A1 (en) 2013-06-05
US8268836B2 (en) 2012-09-18
WO2012015677A1 (en) 2012-02-02
KR20130052740A (en) 2013-05-23
EA201270818A1 (en) 2013-05-30
TWI431008B (en) 2014-03-21
ES2516940T3 (en) 2014-10-31
AU2011282973B2 (en) 2014-03-20
CA2805494A1 (en) 2012-02-02
US20120028984A1 (en) 2012-02-02
TW201219393A (en) 2012-05-16
AU2011282973A1 (en) 2013-01-10
JP2013532687A (en) 2013-08-19
MX2013001247A (en) 2013-03-18
EP2598144B1 (en) 2014-08-13
JP5738412B2 (en) 2015-06-24
WO2012015677A9 (en) 2012-12-13
BR112013002211A2 (en) 2016-05-24
CN103002898A (en) 2013-03-27

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