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IN2009KN03959A - - Google Patents

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Publication number
IN2009KN03959A
IN2009KN03959A IN3959KON2009A IN2009KN03959A IN 2009KN03959 A IN2009KN03959 A IN 2009KN03959A IN 3959KON2009 A IN3959KON2009 A IN 3959KON2009A IN 2009KN03959 A IN2009KN03959 A IN 2009KN03959A
Authority
IN
India
Prior art keywords
pharmaceutically acceptable
relates
patient
administering
treating
Prior art date
Application number
Inventor
Iwao Ojima
Seung-Yub Lee
Original Assignee
Univ New York State Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ New York State Res Found filed Critical Univ New York State Res Found
Publication of IN2009KN03959A publication Critical patent/IN2009KN03959A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/08—Antibacterial agents for leprosy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08—Radicals containing only hydrogen and carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The present invention relates to novel benzimidazole derivatives and pharmaceutically acceptable salts thereof. An- other aspect of the invention relates to methods of treating a patient infected by Mycobacterium tuberculosis or Francisella tulerensis by administering to the patient a benzimidazole derivative or a pharmaceutically acceptable salt thereof.
IN3959KON2009 2007-04-20 2008-04-21 IN2009KN03959A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91298007P 2007-04-20 2007-04-20
PCT/US2008/005084 WO2008130669A1 (en) 2007-04-20 2008-04-21 Benzimidazoles and pharmaceutical compositions thereof

Publications (1)

Publication Number Publication Date
IN2009KN03959A true IN2009KN03959A (en) 2015-08-28

Family

ID=39875833

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3959KON2009 IN2009KN03959A (en) 2007-04-20 2008-04-21

Country Status (17)

Country Link
US (1) US8232410B2 (en)
EP (1) EP2154966B1 (en)
JP (1) JP5400032B2 (en)
CN (1) CN101677553A (en)
AU (1) AU2008242488B2 (en)
BR (1) BRPI0810244A2 (en)
CA (1) CA2684594C (en)
DK (1) DK2154966T3 (en)
EA (1) EA016726B1 (en)
ES (1) ES2434693T3 (en)
HR (1) HRP20131103T1 (en)
IN (1) IN2009KN03959A (en)
MX (1) MX2009011281A (en)
PL (1) PL2154966T3 (en)
PT (1) PT2154966E (en)
SI (1) SI2154966T1 (en)
WO (1) WO2008130669A1 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8232310B2 (en) 2006-12-29 2012-07-31 Georgetown University Targeting of EWS-FLI1 as anti-tumor therapy
US8039502B2 (en) 2007-07-24 2011-10-18 The Ohio State University Research Foundation Anti-infective agents against intracellular pathogens
US20120108823A1 (en) 2009-04-22 2012-05-03 The Ohio State University Research Foundation Anti-francisella agents
PL2475428T3 (en) 2009-09-11 2015-12-31 Probiodrug Ag Heterocylcic derivatives as inhibitors of glutaminyl cyclase
WO2013116823A1 (en) * 2012-02-02 2013-08-08 The Research Foundation Of State University Of New York Benzimidazoles and uses thereof
WO2013142326A1 (en) * 2012-03-23 2013-09-26 The Research Foundation Of State University Of New York 5-carbonylamino-/(sulfonamido-) substituted benz imidazoles and use thereof treatment of tuberculosis
JP6130491B2 (en) 2012-04-12 2017-05-17 ジョージタウン・ユニバーシティＧｅｏｒｇｅｔｏｗｎ Ｕｎｉｖｅｒｓｉｔｙ Methods and compositions for treating Ewing sarcoma family tumors
CN103333170B (en) * 2013-06-14 2016-08-10 清华大学 Benzimidazoles compound and application thereof
KR20160065986A (en) 2013-10-24 2016-06-09 조지타운 유니버시티 Methods and compositions for treating cancer
CN106061951A (en) * 2013-11-22 2016-10-26 纽约州立大学研究基金会 Benzimidazoles and their use in the treatment of tuberculosis
WO2015138611A2 (en) 2014-03-11 2015-09-17 Colorado State University Research Foundation Methods for improved in vitro-in vivo efficacy determination
EP3157904B1 (en) * 2014-06-20 2020-11-18 Institut Pasteur Korea Anti-infective compounds
AU2015328121B2 (en) 2014-10-09 2019-11-21 Oncternal Therapeutics, Inc. Indolinone compounds and uses thereof
US9822122B2 (en) 2016-03-31 2017-11-21 Oncternal Therapeutics, Inc. Indoline analogs and uses thereof
JP6885629B2 (en) 2016-07-29 2021-06-16 オンターナル セラピューティック インコーポレイテッドＯｎｃｔｅｒｎａｌ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． Use of indolinone compounds
CN111303092B (en) * 2020-04-07 2021-05-25 山东昌邑灶户盐化有限公司 2, 4-dinitro-6-chloroaniline derivative, synthetic method and application thereof
TW202317546A (en) 2021-07-09 2023-05-01 美商普萊克斯姆公司 Aryl compounds and pharmaceutical compositions that modulate ikzf2

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61170732A (en) * 1985-01-25 1986-08-01 Fuji Photo Film Co Ltd Silver halide photographic sensitive material
US7405235B2 (en) * 2001-05-04 2008-07-29 Paratek Pharmaceuticals, Inc. Transcription factor modulating compounds and methods of use thereof
AU2005292345B9 (en) * 2004-09-30 2011-12-15 Janssen Pharmaceutica N.V. Novel benzimidazole derivatives useful as selective androgen receptor modulators (SARMS)
WO2007105023A1 (en) * 2006-03-15 2007-09-20 Csir Modulation of phosphoryl transferase activity of glutamine synthetase

Also Published As

Publication number Publication date
BRPI0810244A2 (en) 2014-09-30
EA016726B1 (en) 2012-07-30
WO2008130669A1 (en) 2008-10-30
EP2154966A1 (en) 2010-02-24
CN101677553A (en) 2010-03-24
US20100256203A1 (en) 2010-10-07
US8232410B2 (en) 2012-07-31
ES2434693T3 (en) 2013-12-17
PL2154966T3 (en) 2014-03-31
CA2684594A1 (en) 2008-10-30
EP2154966B1 (en) 2013-08-21
DK2154966T3 (en) 2013-11-18
AU2008242488A1 (en) 2008-10-30
MX2009011281A (en) 2010-03-08
EA200901423A1 (en) 2010-06-30
HRP20131103T1 (en) 2013-12-20
PT2154966E (en) 2013-11-13
EP2154966A4 (en) 2010-12-15
AU2008242488B2 (en) 2014-10-30
SI2154966T1 (en) 2014-02-28
CA2684594C (en) 2015-10-06
JP2010524947A (en) 2010-07-22
JP5400032B2 (en) 2014-01-29

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