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IL89534A0 - Preparation of 1-cyclopropyl-quinolone-carboxylic acids and derivatives thereof and certain novel n-cyclopropyl-anilines used therein - Google Patents

Preparation of 1-cyclopropyl-quinolone-carboxylic acids and derivatives thereof and certain novel n-cyclopropyl-anilines used therein

Info

Publication number
IL89534A0
IL89534A0 IL89534A IL8953489A IL89534A0 IL 89534 A0 IL89534 A0 IL 89534A0 IL 89534 A IL89534 A IL 89534A IL 8953489 A IL8953489 A IL 8953489A IL 89534 A0 IL89534 A0 IL 89534A0
Authority
IL
Israel
Prior art keywords
cyclopropyl
quinolone
derivatives
preparation
carboxylic acids
Prior art date
Application number
IL89534A
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of IL89534A0 publication Critical patent/IL89534A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL89534A 1988-03-11 1989-03-08 Preparation of 1-cyclopropyl-quinolone-carboxylic acids and derivatives thereof and certain novel n-cyclopropyl-anilines used therein IL89534A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3808117A DE3808117A1 (en) 1988-03-11 1988-03-11 N-CYCLOPROPYLANILINE AND THE USE THEREOF IN METHOD FOR THE PRODUCTION OF 1-CYCLOPROPYL-CHINOLONIC CARBONIC ACIDS AND THEIR DERIVATIVES

Publications (1)

Publication Number Publication Date
IL89534A0 true IL89534A0 (en) 1989-09-10

Family

ID=6349470

Family Applications (1)

Application Number Title Priority Date Filing Date
IL89534A IL89534A0 (en) 1988-03-11 1989-03-08 Preparation of 1-cyclopropyl-quinolone-carboxylic acids and derivatives thereof and certain novel n-cyclopropyl-anilines used therein

Country Status (9)

Country Link
EP (1) EP0332033A2 (en)
JP (1) JPH024778A (en)
KR (1) KR890014486A (en)
CN (1) CN1037147A (en)
DE (1) DE3808117A1 (en)
FI (1) FI891122L (en)
HU (1) HUT50781A (en)
IL (1) IL89534A0 (en)
PT (1) PT89955A (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2046091B1 (en) * 1991-09-24 1994-09-01 Elmuquimica Farm Sl NEW PROCEDURE FOR OBTAINING ACID 1-CYCLOPROPIL-6-FLUORO-1,4-DIHIDRO-4-OXO-7- (1-PIPERACINIL) -3-QUINOLIN CARBOXILICO.
ES2050613B1 (en) * 1992-10-16 1996-03-16 Iteve S A NEW PROCEDURE FOR THE PREPARATION OF DERIVATIVES OF THE ACID 1-CICLOPROPIL-3-QUINOLINCARBOXILICO.
HUT67395A (en) * 1993-07-13 1995-04-28 Somfai Method for the n-cyclopropylation of primary and secondary aromatic amines
DE19720540A1 (en) 1997-05-16 1998-11-19 Bayer Ag Process for processing mother liquors from bisphenol synthesis
DE19720541A1 (en) 1997-05-16 1998-11-19 Bayer Ag Process for the continuous production of dihydroxydiphenylalkanes
JP2000229946A (en) * 1998-12-10 2000-08-22 Toyama Chem Co Ltd Process for producing quinolone carboxylic acid and intermediates thereof
US8354427B2 (en) 2004-06-24 2013-01-15 Vertex Pharmaceutical Incorporated Modulators of ATP-binding cassette transporters
HUE032540T2 (en) 2004-06-24 2017-09-28 Vertex Pharma Modulators of ATP-binding cassette transporters
CA2635581C (en) 2005-12-28 2017-02-28 Vertex Pharmaceuticals Incorporated Solid forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
US12458635B2 (en) 2008-08-13 2025-11-04 Vertex Pharmaceuticals Incorporated Pharmaceutical composition and administrations thereof
US20100074949A1 (en) 2008-08-13 2010-03-25 William Rowe Pharmaceutical composition and administration thereof
CN102395565A (en) * 2008-12-05 2012-03-28 俄勒冈健康科学大学 Compounds having antiparasitic or anti-infectious activity
US8598354B2 (en) 2008-12-05 2013-12-03 University Of South Florida Compounds having antiparasitic or anti-infectious activity
EP2821400B1 (en) 2009-03-20 2017-09-27 Vertex Pharmaceuticals Incorporated Process for making modulators of cystic fibrosis transmembrane conductance regulator
US8802700B2 (en) 2010-12-10 2014-08-12 Vertex Pharmaceuticals Incorporated Modulators of ATP-Binding Cassette transporters
RU2692779C2 (en) 2012-02-27 2019-06-27 Вертекс Фармасьютикалз Инкорпорейтед Pharmaceutical composition and introduction thereof
RU2749213C2 (en) 2014-10-07 2021-06-07 Вертекс Фармасьютикалз Инкорпорейтед Co-crystals of transmembrane conduction regulator modulators in cystic fibrosis

Also Published As

Publication number Publication date
DE3808117A1 (en) 1989-09-21
HUT50781A (en) 1990-03-28
FI891122A0 (en) 1989-03-09
FI891122A7 (en) 1989-09-12
FI891122L (en) 1989-09-12
EP0332033A2 (en) 1989-09-13
JPH024778A (en) 1990-01-09
KR890014486A (en) 1989-10-24
CN1037147A (en) 1989-11-15
PT89955A (en) 1989-11-10

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