IL79556A - Pharmaceutical compositions containing inner salts of naphthyridine and related derivatives, their salts, solvates, hydrates and esters, some new such compounds and their preparation - Google Patents

Pharmaceutical compositions containing inner salts of naphthyridine and related derivatives, their salts, solvates, hydrates and esters, some new such compounds and their preparation

Info

Publication number: IL79556A
Authority: IL; Israel
Prior art keywords: carbon atoms; carbon; group; alkyl; hydroxy
Prior art date: 1985-07-29

Application number

IL7955686A

Other languages

English (en)

Original Assignee

Schering Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-07-29

Filing date

1986-07-29

Publication date

1995-05-26

1986-07-29 Application filed by Schering Corp filed Critical Schering Corp

1995-05-26 Publication of IL79556A publication Critical patent/IL79556A/en

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/36—Sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Rheumatology (AREA)
Transplantation (AREA)
Pain & Pain Management (AREA)
Pulmonology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Quinoline Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Professional, Industrial, Or Sporting Protective Garments (AREA)
Outer Garments And Coats (AREA)
Steroid Compounds (AREA)

IL7955686A 1985-07-29 1986-07-29 Pharmaceutical compositions containing inner salts of naphthyridine and related derivatives, their salts, solvates, hydrates and esters, some new such compounds and their preparation IL79556A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/760,196 US4684727A (en)	1985-07-29	1985-07-29	Zwitterionic 1,8-naphthyridine and pyrazino[2,3-b]pyridine containing compounds useful as anti-allergic, anti-inflammatory and cycloprotective agents

Publications (1)

Publication Number	Publication Date
IL79556A true IL79556A (en)	1995-05-26

Family

ID=25058394

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL7955686A IL79556A (en)	1985-07-29	1986-07-29	Pharmaceutical compositions containing inner salts of naphthyridine and related derivatives, their salts, solvates, hydrates and esters, some new such compounds and their preparation

Country Status (23)

Country	Link
US (4)	US4684727A (fr)
EP (1)	EP0232328B1 (fr)
JP (1)	JPH0794455B2 (fr)
KR (1)	KR900003490B1 (fr)
AT (1)	ATE74756T1 (fr)
AU (1)	AU597587B2 (fr)
CA (1)	CA1263654A (fr)
CZ (1)	CZ413991A3 (fr)
DE (1)	DE3684903D1 (fr)
DK (1)	DK157787A (fr)
FI (1)	FI871345A7 (fr)
HU (1)	HU201550B (fr)
IE (1)	IE59298B1 (fr)
IL (1)	IL79556A (fr)
MX (1)	MX9203320A (fr)
MY (1)	MY101970A (fr)
NO (1)	NO166862C (fr)
NZ (1)	NZ217016A (fr)
OA (1)	OA08501A (fr)
PH (1)	PH23887A (fr)
PT (1)	PT83080B (fr)
WO (1)	WO1987000752A2 (fr)
ZA (1)	ZA865631B (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4684727A (en) *	1985-07-29	1987-08-04	Schering Corporation	Zwitterionic 1,8-naphthyridine and pyrazino[2,3-b]pyridine containing compounds useful as anti-allergic, anti-inflammatory and cycloprotective agents
US5037826A (en) *	1986-10-15	1991-08-06	Schering Corporation	1-substituted naphthyridine and pyridopyrazine derivatives
US5045542A (en) *	1986-10-20	1991-09-03	Schering Corporation	Immune suppression method employing aryl-substituted naphthyridine and pyridopyrazine derivatives
US5350755A (en) *	1986-12-05	1994-09-27	Schering Corporation	Compounds and methods for treating hyperproliferative skin disease
CA1309658C (fr) *	1986-12-05	1992-11-03	David J. Blythin	Compositions pharmaceutiques pour le traitement des maladies hyperproliferatives de la peau
WO1989000571A2 (fr) *	1987-07-22	1989-01-26	Schering Corporation	Composes bicycliques, leur utilisation comme produits pharmaceutiques, leur preparation et composes intermediaires utiles dans leur preparation
US4897487A (en) *	1988-04-06	1990-01-30	Schering Corporation	Process for preparing intermediates for pharmaceutically useful bicyclic compounds
US5180823A (en) *	1988-04-06	1993-01-19	Schering Corporation	Processes for preparing bicyclic compounds
US5079360A (en) *	1988-04-06	1992-01-07	Schering Corporation	Processes for preparing bicyclic compounds and intermediates thereof
US5341575A (en) *	1989-11-01	1994-08-30	Chisum Finis L	Apparatus to gather, display, and/or print vehicle chassis measurement data for accurate repair of collision damaged vehicles
US5175151A (en) *	1990-09-07	1992-12-29	Schering Corporation	Antiviral compounds and antihypertensive compounds
WO1992004327A1 (fr) *	1990-09-07	1992-03-19	Schering Corporation	Composes antiviraux et composes antihypertenseurs
US5760034A (en) *	1990-11-30	1998-06-02	Schering Corporation	Heterocyclic substituted naphthyridinones and methods and compositions employing them
GB9026389D0 (en) *	1990-12-05	1991-01-23	Merck Sharp & Dohme	Therapeutic agents
US5179093A (en) *	1991-05-10	1993-01-12	Schering Corporation	Quinoline-diones
JP2683783B2 (ja) *	1992-07-10	1997-12-03	雪印乳業株式会社	シェーグレン症候群治療剤
US7083777B1 (en) *	1999-04-02	2006-08-01	The Brigham And Women's Hospital, Inc.	Immunomodulating polymers
SV2003000753A (es)	2000-12-05	2003-06-16	Brigham & Womens Hospital	Uso de polisacaridos zwitterionicos para la especifica modulacion del progreso inmunologico
CA2520865A1 (fr) *	2003-03-31	2004-10-21	The Brigham And Women's Hospital, Inc.	Immunomodulateurs zwitterioniques destines au traitement de l'asthme et des allergies
US8206726B2 (en)	2006-02-06	2012-06-26	The Brigham And Women's Hospital, Inc.	Zwitterionic polysaccharides for promotion of immune system maturation and health
EP2731617A4 (fr)	2011-07-12	2015-07-01	Brigham & Womens Hospital	Compositions de psa contenant des lipides, procédés d'isolement et procédés pour les utiliser
EP3337321A4 (fr)	2015-08-19	2019-07-17	President and Fellows of Harvard College	Compositions de psa lipidés et procédés associés
EP3484441A4 (fr)	2016-07-15	2020-03-18	President and Fellows of Harvard College	Compositions de glycolipide et procédés d'utilisation

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4264602A (en) *	1975-08-15	1981-04-28	Sandoz, Inc.	4-Hydroxy-3-nitro-pyrido[2,3-B]pyridine-2(1H)-ones
FR2469962A1 (fr) *	1979-11-21	1981-05-29	Vallourec	Procede et dispositif pour la fabrication d'un tube d'acier sans soudure par laminage a chaud sur mandrin
DE3368929D1 (de) *	1982-04-26	1987-02-12	Schering Corp	1,8-naphthyridine and 1,5,8-azanaphthyridine derivatives
US4452800A (en) *	1982-04-26	1984-06-05	Schering Corporation	Salts of 3(n-butyl)-4-hydroxy-1-phenyl-1,8-naphthyridine-2(1H)-one and their use in treating chronic obstructive lung diseases
US4551463A (en) *	1982-11-03	1985-11-05	Schering Corporation	Composition containing 1-phenyl-1,8-naphthridin-2(1H)-ones and a non-steroidal anti-inflammatory drug
US4628055A (en) *	1982-11-03	1986-12-09	Schering Corporation	Method for treating allergic reactions and compositions therefore
US4684727A (en) *	1985-07-29	1987-08-04	Schering Corporation	Zwitterionic 1,8-naphthyridine and pyrazino[2,3-b]pyridine containing compounds useful as anti-allergic, anti-inflammatory and cycloprotective agents

1985
- 1985-07-29 US US06/760,196 patent/US4684727A/en not_active Expired - Lifetime
1986
- 1986-07-25 PH PH34069A patent/PH23887A/en unknown
- 1986-07-25 DE DE8686904707T patent/DE3684903D1/de not_active Expired - Lifetime
- 1986-07-25 HU HU862869A patent/HU201550B/hu not_active IP Right Cessation
- 1986-07-25 WO PCT/US1986/001518 patent/WO1987000752A2/fr not_active Ceased
- 1986-07-25 AU AU61479/86A patent/AU597587B2/en not_active Ceased
- 1986-07-25 EP EP86904707A patent/EP0232328B1/fr not_active Expired - Lifetime
- 1986-07-25 KR KR1019870700274A patent/KR900003490B1/ko not_active Expired
- 1986-07-25 JP JP61504059A patent/JPH0794455B2/ja not_active Expired - Lifetime
- 1986-07-25 AT AT86904707T patent/ATE74756T1/de not_active IP Right Cessation
- 1986-07-28 PT PT83080A patent/PT83080B/pt not_active IP Right Cessation
- 1986-07-28 ZA ZA865631A patent/ZA865631B/xx unknown
- 1986-07-28 IE IE199786A patent/IE59298B1/en not_active IP Right Cessation
- 1986-07-29 CA CA000514897A patent/CA1263654A/fr not_active Expired
- 1986-07-29 NZ NZ217016A patent/NZ217016A/xx unknown
- 1986-07-29 IL IL7955686A patent/IL79556A/en not_active IP Right Cessation
1987
- 1987-03-16 OA OA59087A patent/OA08501A/xx unknown
- 1987-03-27 NO NO871311A patent/NO166862C/no unknown
- 1987-03-27 FI FI871345A patent/FI871345A7/fi not_active Application Discontinuation
- 1987-03-27 DK DK157787A patent/DK157787A/da not_active IP Right Cessation
- 1987-07-22 US US07/076,450 patent/US4794116A/en not_active Expired - Fee Related
- 1987-07-22 US US07/076,469 patent/US4782067A/en not_active Expired - Fee Related
- 1987-08-10 MY MYPI87001247A patent/MY101970A/en unknown
1988
- 1988-07-22 US US07/223,458 patent/US4902693A/en not_active Expired - Fee Related
1991
- 1991-12-30 CZ CS914139A patent/CZ413991A3/cs unknown
1992
- 1992-06-25 MX MX9203320A patent/MX9203320A/es unknown

Also Published As

Publication number	Publication date
JPS63500453A (ja)	1988-02-18
FI871345A0 (fi)	1987-03-27
US4794116A (en)	1988-12-27
MX9203320A (es)	1992-07-01
OA08501A (en)	1988-07-29
EP0232328A1 (fr)	1987-08-19
DK157787D0 (da)	1987-03-27
PT83080A (en)	1986-08-01
HU201550B (en)	1990-11-28
AU597587B2 (en)	1990-06-07
JPH0794455B2 (ja)	1995-10-11
ZA865631B (en)	1987-03-25
NO871311L (no)	1987-03-27
KR900003490B1 (ko)	1990-05-21
KR870700352A (ko)	1987-12-28
WO1987000752A2 (fr)	1987-02-12
EP0232328B1 (fr)	1992-04-15
IE861997L (en)	1987-01-29
US4684727A (en)	1987-08-04
PT83080B (pt)	1989-01-30
DK157787A (da)	1987-03-27
IE59298B1 (en)	1994-02-09
CZ413991A3 (en)	1993-01-13
WO1987000752A3 (fr)	1987-05-21
AU6147986A (en)	1987-03-05
NO871311D0 (no)	1987-03-27
US4782067A (en)	1988-11-01
NO166862B (no)	1991-06-03
US4902693A (en)	1990-02-20
ATE74756T1 (de)	1992-05-15
PH23887A (en)	1989-12-18
DE3684903D1 (de)	1992-05-21
MY101970A (en)	1992-02-29
FI871345A7 (fi)	1987-03-27
HUT42481A (en)	1987-07-28
NZ217016A (en)	1989-11-28
CA1263654A (fr)	1989-12-05
NO166862C (no)	1991-09-11

Publication	Publication Date	Title
EP0232328B1 (fr)	1992-04-15	Composes bicycliques amphoteriques et leurs sels, solvats, hydrates et esters
AU656859B2 (en)	1995-02-16	Aryl group- or aromatic heterocyclic group-substituted aminoquinolone derivatives and anti-HIV agent
JP2571904B2 (ja)	1997-01-16	抗虚血剤としての２−（４−ヒドロキシピペリジノ）−１−アルカノール誘導体
US6737424B2 (en)	2004-05-18	Alpha-substituted pyridazino quinoline compounds
JPH0267282A (ja)	1990-03-07	四環式ケトン
JP4108123B2 (ja)	2008-06-25	Ｎｍｄａアンタゴニストとしてのテトラヒドロキノリン
DE69904818T2 (de)	2003-10-09	Thienodipyridinderivate, ihre herstellung und verwendung
JPH02209876A (ja)	1990-08-21	イミダゾール誘導体
IE860125L (en)	1986-07-16	Piperazinyl pyridines
US5373015A (en)	1994-12-13	Fused pyridine derivatives useful as angiotensin II antagonists
JPH11512413A (ja)	1999-10-26	ジアリールアルケニルアミン誘導体
AU632461B2 (en)	1993-01-07	Bicyclic compounds, their use as pharmaceuticals, their preparation, and intermediates useful in their preparation
CN101203517A (zh)	2008-06-18	对呼吸道合胞病毒具有活性的1-(2-氨基-3-(取代烷基)-3h-苯并咪唑基甲基)-3-取代-1,3-二氢-苯并咪唑-2-酮
US4780477A (en)	1988-10-25	Isatin compositions having anti-ulcer activities
JPS61204186A (ja)	1986-09-10	ピリダジノピロロイソキノリン誘導体
KR940006285B1 (ko)	1994-07-14	이환식 화합물, 이의 제조방법 및 이의 제조에 유용한 중간체
JP2004509870A (ja)	2004-04-02	ヒスタミンｈ１およびヒスタミンｈ３双方のアゴニストまたはアンタゴニストとしての置換イミダゾール
NZ235348A (en)	1992-12-23	Process for preparing substituted acetamide derivatives, and the acetamide derivatives when so prepared
US5760034A (en)	1998-06-02	Heterocyclic substituted naphthyridinones and methods and compositions employing them
JPS61249970A (ja)	1986-11-07	新規な置換２−（ｎ−アルキニル−ｎ−フエニルアミノ）イミダゾリン誘導体
EP0309765A2 (fr)	1989-04-05	1(2H)-Phtalazinones comme médicaments cytoprotectifs
JPS60174785A (ja)	1985-09-09	ピラゾロピリジン誘導体，その製法及びそれを含む医薬組成物
DE3705933A1 (de)	1988-09-08	3-n-arylamino-1-(4,5,6,7-tetrahydro-2- benzothiazolyl)-2-pyrazoline, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
JPS59212469A (ja)	1984-12-01	医薬としてのピロリン誘導体とその製法
JPH1072439A (ja)	1998-03-17	ピリジン誘導体

Legal Events

Date	Code	Title	Description
1997-04-15	RH	Patent void