IL318535A - Jak1/jak2/tyk2 inhibitors for topical treatment of dermatological diseases - Google Patents
Jak1/jak2/tyk2 inhibitors for topical treatment of dermatological diseasesInfo
- Publication number
- IL318535A IL318535A IL318535A IL31853525A IL318535A IL 318535 A IL318535 A IL 318535A IL 318535 A IL318535 A IL 318535A IL 31853525 A IL31853525 A IL 31853525A IL 318535 A IL318535 A IL 318535A
- Authority
- IL
- Israel
- Prior art keywords
- jak1
- jak2
- topical treatment
- dermatological diseases
- tyk2 inhibitors
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2022113873 | 2022-08-22 | ||
| PCT/CN2023/112361 WO2024041397A1 (en) | 2022-08-22 | 2023-08-10 | Jak1/jak2/tyk2 inhibitors for topical treatment of dermatological diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL318535A true IL318535A (en) | 2025-03-01 |
Family
ID=90012519
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL318535A IL318535A (en) | 2022-08-22 | 2023-08-10 | Jak1/jak2/tyk2 inhibitors for topical treatment of dermatological diseases |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP4577535A1 (en) |
| JP (1) | JP2025529836A (en) |
| KR (1) | KR20250051678A (en) |
| AU (1) | AU2023328280A1 (en) |
| CA (1) | CA3263043A1 (en) |
| IL (1) | IL318535A (en) |
| MX (1) | MX2025002033A (en) |
| WO (1) | WO2024041397A1 (en) |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009064835A1 (en) * | 2007-11-16 | 2009-05-22 | Incyte Corporation | 4-pyrazolyl-n-arylpyrimidin-2-amines and 4-pyrazolyl-n-heteroarylpyrimidin-2-amines as janus kinase inhibitors |
| CA2815330A1 (en) * | 2010-11-09 | 2012-05-18 | Cellzome Limited | Pyridine compounds and aza analogues thereof as tyk2 inhibitors |
| US9745320B2 (en) * | 2013-01-18 | 2017-08-29 | Guangzhou Maxinovel Pharmaceuticals Co., Ltd. | Five-and-six-membered heterocyclic compound, and preparation method, pharmaceutical composition and use thereof |
| WO2020118683A1 (en) * | 2018-12-14 | 2020-06-18 | Lynk Pharmaceuticals Co. Ltd. | Benzamides of pyrazolyl-amino-pyrimidinyl derivatives, and compositions and methods thereof |
| CN110862380A (en) * | 2019-10-24 | 2020-03-06 | 嘉兴特科罗生物科技有限公司 | a small molecule compound |
| CN110862376A (en) * | 2019-10-24 | 2020-03-06 | 嘉兴特科罗生物科技有限公司 | Small molecule compound |
| CN114181199B (en) * | 2020-09-15 | 2023-09-26 | 成都赜灵生物医药科技有限公司 | 2, 4-disubstituted pyrimidine derivative, preparation method and application thereof |
| WO2023060202A1 (en) * | 2021-10-06 | 2023-04-13 | Aerie Pharmaceuticals, Inc. | Janus kinase inhibiting pyrazole compounds and uses thereof |
-
2023
- 2023-08-10 EP EP23856487.6A patent/EP4577535A1/en active Pending
- 2023-08-10 KR KR1020257006080A patent/KR20250051678A/en active Pending
- 2023-08-10 JP JP2025510354A patent/JP2025529836A/en active Pending
- 2023-08-10 AU AU2023328280A patent/AU2023328280A1/en active Pending
- 2023-08-10 WO PCT/CN2023/112361 patent/WO2024041397A1/en not_active Ceased
- 2023-08-10 IL IL318535A patent/IL318535A/en unknown
- 2023-08-10 CA CA3263043A patent/CA3263043A1/en active Pending
-
2025
- 2025-02-19 MX MX2025002033A patent/MX2025002033A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP4577535A1 (en) | 2025-07-02 |
| KR20250051678A (en) | 2025-04-17 |
| JP2025529836A (en) | 2025-09-09 |
| CA3263043A1 (en) | 2024-02-29 |
| MX2025002033A (en) | 2025-04-02 |
| AU2023328280A1 (en) | 2025-02-13 |
| WO2024041397A1 (en) | 2024-02-29 |
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