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IL163703A0 - Coupling low-molecular substances to a modified polysaccharide - Google Patents

Coupling low-molecular substances to a modified polysaccharide

Info

Publication number
IL163703A0
IL163703A0 IL16370303A IL16370303A IL163703A0 IL 163703 A0 IL163703 A0 IL 163703A0 IL 16370303 A IL16370303 A IL 16370303A IL 16370303 A IL16370303 A IL 16370303A IL 163703 A0 IL163703 A0 IL 163703A0
Authority
IL
Israel
Prior art keywords
functional groups
aldehyde groups
groups
terminal aldehyde
covalent linkage
Prior art date
Application number
IL16370303A
Other languages
English (en)
Original Assignee
Fresenius Kabi De Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fresenius Kabi De Gmbh filed Critical Fresenius Kabi De Gmbh
Publication of IL163703A0 publication Critical patent/IL163703A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
IL16370303A 2002-03-06 2003-02-28 Coupling low-molecular substances to a modified polysaccharide IL163703A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10209822A DE10209822A1 (de) 2002-03-06 2002-03-06 Kopplung niedermolekularer Substanzen an ein modifiziertes Polysaccharid
PCT/EP2003/002084 WO2003074088A2 (fr) 2002-03-06 2003-02-28 Couplage de substances a faible poids moleculaire avec un polysaccharide modifie

Publications (1)

Publication Number Publication Date
IL163703A0 true IL163703A0 (en) 2005-12-18

Family

ID=27771030

Family Applications (2)

Application Number Title Priority Date Filing Date
IL16370303A IL163703A0 (en) 2002-03-06 2003-02-28 Coupling low-molecular substances to a modified polysaccharide
IL163703A IL163703A (en) 2002-03-06 2004-08-24 Coupling low-molecular substances to a modified polysaccharide

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL163703A IL163703A (en) 2002-03-06 2004-08-24 Coupling low-molecular substances to a modified polysaccharide

Country Status (16)

Country Link
US (2) US8466277B2 (fr)
EP (2) EP2269655A3 (fr)
JP (1) JP2005530699A (fr)
CN (1) CN1638809A (fr)
AT (1) ATE506078T1 (fr)
AU (1) AU2003229552C1 (fr)
BR (1) BR0308199A (fr)
CA (1) CA2478480C (fr)
DE (2) DE10209822A1 (fr)
IL (2) IL163703A0 (fr)
MX (1) MXPA04008515A (fr)
NO (1) NO20044122L (fr)
PL (1) PL374543A1 (fr)
RU (1) RU2327702C2 (fr)
WO (1) WO2003074088A2 (fr)
ZA (1) ZA200408016B (fr)

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DE10209821A1 (de) 2002-03-06 2003-09-25 Biotechnologie Ges Mittelhesse Kopplung von Proteinen an ein modifiziertes Polysaccharid
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DE10242076A1 (de) * 2002-09-11 2004-03-25 Fresenius Kabi Deutschland Gmbh HAS-Allergen-Konjugate
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DE10324710A1 (de) * 2003-05-30 2004-12-16 Supramol Parenteral Colloids Gmbh Stärkederivatkomplexe
HRP20110056T1 (hr) * 2003-08-08 2011-02-28 Fresenius Kabi Deutschland Gmbh Konjugati hidroksialkil škroba i g-csf
BRPI0412671A (pt) * 2003-08-08 2006-10-03 Fresenius Kabi De Gmbh conjugados de um polìmero e uma proteìna ligados por um grupo de ligação de oxima
WO2005014655A2 (fr) * 2003-08-08 2005-02-17 Fresenius Kabi Deutschland Gmbh Conjugues d'amidon d'hydroxyalkyle et de proteine
CN101659704A (zh) * 2004-03-11 2010-03-03 弗雷泽纽斯卡比德国有限公司 通过还原氨基化制备的羟烷基淀粉和蛋白质的偶联物
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CN106928339A (zh) 2008-07-23 2017-07-07 Ambrx 公司 经修饰的牛g‑csf多肽和其用途
SE533540C2 (sv) * 2008-12-19 2010-10-19 Neoinvent Medical Engineering Ab Administrerinssystem för administrering av en substans i munhålan
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WO2011051466A1 (fr) 2009-11-02 2011-05-05 Novartis Ag Molécules de liaison anti-idiotypiques à base de fibronectine et leurs utilisations
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EP2591008A1 (fr) * 2010-07-09 2013-05-15 Fresenius Kabi Deutschland GmbH Conjugués comprenant un amidon hydroxyalkylé et un agent cytotoxique et leur procédé de préparation
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RU2560699C2 (ru) * 2013-08-02 2015-08-20 федеральное государственное автономное образовательное учреждение высшего профессионального образования "Национальный исследовательский ядерный университет МИФИ" (НИЯУ МИФИ) Способ создания наноразмерной диагностической метки на основе конъюгатов наночастиц и однодоменных антител
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US12396970B2 (en) 2021-08-20 2025-08-26 AltaThera Pharmaceuticals LLC Anti-arrhythmic compositions and methods
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DE50313632D1 (de) 2011-06-01
US8466277B2 (en) 2013-06-18
IL163703A (en) 2009-02-11
EP2269655A3 (fr) 2011-04-27
EP2269655A2 (fr) 2011-01-05
WO2003074088A3 (fr) 2004-08-26
AU2003229552A1 (en) 2003-09-16
NO20044122L (no) 2004-09-28
US20060217293A1 (en) 2006-09-28
EP1480681A2 (fr) 2004-12-01
DE10209822A1 (de) 2003-09-25
RU2004129724A (ru) 2006-04-27
ZA200408016B (en) 2005-11-30
CA2478480C (fr) 2012-07-17
US20120259107A1 (en) 2012-10-11
EP1480681B1 (fr) 2011-04-20
BR0308199A (pt) 2006-06-06
AU2003229552C1 (en) 2009-12-17
CA2478480A1 (fr) 2003-09-12
PL374543A1 (en) 2005-10-31
MXPA04008515A (es) 2005-09-20
CN1638809A (zh) 2005-07-13
WO2003074088A2 (fr) 2003-09-12
JP2005530699A (ja) 2005-10-13
ATE506078T1 (de) 2011-05-15
RU2327702C2 (ru) 2008-06-27

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