IL163697A - Suspensions of crystalline tiotropium bromide monohydrate and uses thereof - Google Patents

Suspensions of crystalline tiotropium bromide monohydrate and uses thereof

Info

Publication number: IL163697A
Authority: IL; Israel
Prior art keywords: suspensions; tiotropium bromide; bromide monohydrate; crystalline tiotropium; crystalline
Prior art date: 2002-03-28

Application number

IL163697A

Original Assignee

Boehringer Ingelheim Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-03-28

Filing date

2004-08-24

Publication date

2011-03-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=28050989&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL163697(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2004-08-24 Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma

2011-03-31 Publication of IL163697A publication Critical patent/IL163697A/en

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Pulmonology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Dispersion Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Otolaryngology (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

IL163697A 2002-03-28 2004-08-24 Suspensions of crystalline tiotropium bromide monohydrate and uses thereof IL163697A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10214263A DE10214263A1 (en)	2002-03-28	2002-03-28	HFA suspension formulations containing an anticholinergic
PCT/EP2003/002898 WO2003082252A1 (en)	2002-03-28	2003-03-20	Hfa-suspension formulations containing an anticholinergic

Publications (1)

Publication Number	Publication Date
IL163697A true IL163697A (en)	2011-03-31

Family

ID=28050989

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
IL16369703A IL163697A0 (en)	2002-03-28	2003-03-20	Hfa-suspension formulations containing an anticholinergic
IL163697A IL163697A (en)	2002-03-28	2004-08-24	Suspensions of crystalline tiotropium bromide monohydrate and uses thereof

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
IL16369703A IL163697A0 (en)	2002-03-28	2003-03-20	Hfa-suspension formulations containing an anticholinergic

Country Status (26)

Country	Link
EP (2)	EP1492513B1 (en)
JP (1)	JP4480401B2 (en)
KR (1)	KR101066801B1 (en)
CN (1)	CN1329023C (en)
AT (1)	ATE339953T1 (en)
AU (1)	AU2003209743B2 (en)
BR (1)	BR0308764A (en)
CA (1)	CA2479640C (en)
CY (1)	CY1105543T1 (en)
DE (2)	DE10214263A1 (en)
DK (1)	DK1492513T3 (en)
EA (1)	EA007239B1 (en)
EC (1)	ECSP045321A (en)
ES (1)	ES2273020T3 (en)
HR (1)	HRP20040889B1 (en)
IL (2)	IL163697A0 (en)
ME (1)	ME00247B (en)
MX (1)	MXPA04009337A (en)
NO (1)	NO20044005L (en)
NZ (1)	NZ536043A (en)
PL (1)	PL371296A1 (en)
PT (1)	PT1492513E (en)
RS (1)	RS52178B (en)
UA (1)	UA78557C2 (en)
WO (1)	WO2003082252A1 (en)
ZA (1)	ZA200405638B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2005259523B2 (en) †	2004-07-02	2011-06-09	Boehringer Ingelheim International Gmbh	Aerosol suspension formulations containing TG 227 ea or TG 134 a as a propellant
TWI396541B (en) *	2005-10-10	2013-05-21	Boehringer Ingelheim Int	Novel combinations of medicaments for the treatment of respiratory diseases
GB201200504D0 (en) *	2011-12-19	2012-02-22	Teva Branded Pharmaceutical Prod R & D Inc	An inhaler
GB201200525D0 (en)	2011-12-19	2012-02-29	Teva Branded Pharmaceutical Prod R & D Inc	An inhalable medicament
EP2705838A1 (en) *	2012-09-06	2014-03-12	Xspray Microparticles Ab	Tiotropium preparations
CN104918604A (en) *	2012-10-23	2015-09-16	西普拉有限公司	Pharmaceutical composition
US10034866B2 (en)	2014-06-19	2018-07-31	Teva Branded Pharmaceutical Products R&D, Inc.	Inhalable medicament comprising tiotropium
CN107056629B (en) *	2017-04-27	2019-04-30	河北科技大学	A kind of preparation method of anhydrous halogenated choline and its derivative single crystal

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5610163A (en) *	1989-09-16	1997-03-11	Boehringer Ingelheim Gmbh	Esters of thienyl carboxylic acids and amino alcohols and their quaternization products
GB2326334A (en) *	1997-06-13	1998-12-23	Chiesi Farma Spa	Pharmaceutical aerosol compositions
WO2000007567A1 (en) *	1998-08-04	2000-02-17	Jago Research Ag	Medicinal aerosol formulations
DZ2947A1 (en) *	1998-11-25	2004-03-15	Chiesi Farma Spa	Pressure metered dose inhaler.
DE19921693A1 (en) *	1999-05-12	2000-11-16	Boehringer Ingelheim Pharma	Pharmaceutical composition for treating respiratory disorders, e.g. asthma, comprises combination of anticholinergic and beta-mimetic agents having synergistic bronchospasmolytic activity and reduced side-effects
IT1317846B1 (en) *	2000-02-22	2003-07-15	Chiesi Farma Spa	FORMULATIONS CONTAINING AN ANTICOLINERGIC DRUG FOR THE TREATMENT OF CHRONIC OBSTRUCTIVE BRONCOPNEUMOPATHY.
GB0009605D0 (en) *	2000-04-18	2000-06-07	Glaxo Group Ltd	Medicaments
AP1572A (en) *	2000-10-12	2006-02-13	Boehringer Ingelheim Pharma	Crystalline monohydrate, method for producing the same and use thereof in the production of a medicament.
EP1333830A2 (en) *	2000-10-31	2003-08-13	Boehringer Ingelheim Pharma GmbH & Co.KG	Novel medicament compositions based on anticholinergics and corticosteroids
DE10056104A1 (en) *	2000-11-13	2002-05-23	Boehringer Ingelheim Pharma	Drug compositions useful for treatment of respiratory diseases, especially asthma and chronic obstructive pulmonary disease comprises tiotropium salts and salmeterol salts

2002
- 2002-03-28 DE DE10214263A patent/DE10214263A1/en not_active Withdrawn
2003
- 2003-03-20 IL IL16369703A patent/IL163697A0/en active IP Right Grant
- 2003-03-20 HR HRP20040889AA patent/HRP20040889B1/en not_active IP Right Cessation
- 2003-03-20 ES ES03745193T patent/ES2273020T3/en not_active Expired - Lifetime
- 2003-03-20 DK DK03745193T patent/DK1492513T3/en active
- 2003-03-20 JP JP2003579790A patent/JP4480401B2/en not_active Expired - Lifetime
- 2003-03-20 AU AU2003209743A patent/AU2003209743B2/en not_active Ceased
- 2003-03-20 ME MEP-2008-474A patent/ME00247B/en unknown
- 2003-03-20 WO PCT/EP2003/002898 patent/WO2003082252A1/en not_active Ceased
- 2003-03-20 PT PT03745193T patent/PT1492513E/en unknown
- 2003-03-20 CA CA2479640A patent/CA2479640C/en not_active Expired - Fee Related
- 2003-03-20 MX MXPA04009337A patent/MXPA04009337A/en active IP Right Grant
- 2003-03-20 RS YU85904A patent/RS52178B/en unknown
- 2003-03-20 NZ NZ536043A patent/NZ536043A/en not_active IP Right Cessation
- 2003-03-20 CN CNB038072491A patent/CN1329023C/en not_active Expired - Lifetime
- 2003-03-20 BR BR0308764-6A patent/BR0308764A/en not_active IP Right Cessation
- 2003-03-20 UA UA20041008770A patent/UA78557C2/en unknown
- 2003-03-20 EP EP03745193A patent/EP1492513B1/en not_active Expired - Lifetime
- 2003-03-20 AT AT03745193T patent/ATE339953T1/en active
- 2003-03-20 DE DE50305118T patent/DE50305118D1/en not_active Expired - Lifetime
- 2003-03-20 PL PL03371296A patent/PL371296A1/en unknown
- 2003-03-20 EA EA200401190A patent/EA007239B1/en not_active IP Right Cessation
- 2003-03-20 EP EP06115508.1A patent/EP1695701B1/en not_active Expired - Lifetime
- 2003-03-20 KR KR1020047015356A patent/KR101066801B1/en not_active Expired - Fee Related
2004
- 2004-07-15 ZA ZA2004/05638A patent/ZA200405638B/en unknown
- 2004-08-24 IL IL163697A patent/IL163697A/en unknown
- 2004-09-23 NO NO20044005A patent/NO20044005L/en not_active Application Discontinuation
- 2004-09-28 EC EC2004005321A patent/ECSP045321A/en unknown
2006
- 2006-09-26 CY CY20061101380T patent/CY1105543T1/en unknown

Also Published As

Publication number	Publication date
DK1492513T3 (en)	2006-12-18
ZA200405638B (en)	2005-07-27
MXPA04009337A (en)	2005-01-25
MEP47408A (en)	2011-02-10
NO20044005L (en)	2004-10-05
EA007239B1 (en)	2006-08-25
DE10214263A1 (en)	2003-10-16
ES2273020T3 (en)	2007-05-01
ME00247B (en)	2011-05-10
HK1079091A1 (en)	2006-03-31
UA78557C2 (en)	2007-04-10
AU2003209743B2 (en)	2008-03-06
PL371296A1 (en)	2005-06-13
CN1642534A (en)	2005-07-20
EP1695701B1 (en)	2015-01-07
DE50305118D1 (en)	2006-11-02
EP1492513A1 (en)	2005-01-05
HRP20040889A2 (en)	2004-12-31
JP2005529087A (en)	2005-09-29
RS52178B (en)	2012-10-31
HRP20040889B1 (en)	2012-11-30
NZ536043A (en)	2005-09-30
CY1105543T1 (en)	2010-07-28
CA2479640A1 (en)	2003-10-09
BR0308764A (en)	2005-01-11
PT1492513E (en)	2006-12-29
CA2479640C (en)	2010-09-28
JP4480401B2 (en)	2010-06-16
EP1492513B1 (en)	2006-09-20
EA200401190A1 (en)	2005-04-28
KR101066801B1 (en)	2011-09-22
KR20040098031A (en)	2004-11-18
CN1329023C (en)	2007-08-01
AU2003209743A1 (en)	2003-10-13
IL163697A0 (en)	2005-12-18
EP1695701A2 (en)	2006-08-30
ATE339953T1 (en)	2006-10-15
ECSP045321A (en)	2005-01-28
EP1695701A3 (en)	2010-04-28
YU85904A (en)	2006-08-17
WO2003082252A1 (en)	2003-10-09

Publication	Publication Date	Title
LT1785422T (en)	2017-02-10	Micronised crystalline tiotropium bromide
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IL163697A (en)	2011-03-31	Suspensions of crystalline tiotropium bromide monohydrate and uses thereof
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TW529412U (en)	2003-04-21	Structure of turnable proxabrush
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TW537353U (en)	2003-06-11	Structure of sound absorbing unit

Legal Events

Date	Code	Title
2013-03-24	KB	Patent renewed
2017-02-28	KB	Patent renewed
2021-03-25	KB	Patent renewed