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IL161862A0 - Methods and compositions for correction of cardiac conduction disturbances - Google Patents

Methods and compositions for correction of cardiac conduction disturbances

Info

Publication number
IL161862A0
IL161862A0 IL16186202A IL16186202A IL161862A0 IL 161862 A0 IL161862 A0 IL 161862A0 IL 16186202 A IL16186202 A IL 16186202A IL 16186202 A IL16186202 A IL 16186202A IL 161862 A0 IL161862 A0 IL 161862A0
Authority
IL
Israel
Prior art keywords
correction
compositions
methods
cardiac conduction
conduction disturbances
Prior art date
Application number
IL16186202A
Other languages
English (en)
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Publication of IL161862A0 publication Critical patent/IL161862A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0658—Skeletal muscle cells, e.g. myocytes, myotubes, myoblasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/998—Proteins not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Rheumatology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
IL16186202A 2001-11-08 2002-11-07 Methods and compositions for correction of cardiac conduction disturbances IL161862A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33735201P 2001-11-08 2001-11-08
PCT/US2002/035932 WO2003039344A2 (en) 2001-11-08 2002-11-07 Methods and compositions for correction of cardiac conduction disturbances

Publications (1)

Publication Number Publication Date
IL161862A0 true IL161862A0 (en) 2005-11-20

Family

ID=23320214

Family Applications (1)

Application Number Title Priority Date Filing Date
IL16186202A IL161862A0 (en) 2001-11-08 2002-11-07 Methods and compositions for correction of cardiac conduction disturbances

Country Status (10)

Country Link
US (2) US7252819B2 (xx)
EP (1) EP1453382A4 (xx)
JP (1) JP2005527482A (xx)
CN (1) CN1612691A (xx)
AU (1) AU2002359371A1 (xx)
BR (1) BR0214018A (xx)
CA (1) CA2465476A1 (xx)
IL (1) IL161862A0 (xx)
MX (1) MXPA04004396A (xx)
WO (1) WO2003039344A2 (xx)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1453382A4 (en) * 2001-11-08 2005-05-18 Univ California METHOD AND COMPOSITIONS FOR CORRECTING CROSS-BREAKDOWN OF THE HEART
WO2003094855A1 (en) * 2002-05-08 2003-11-20 The Regents Of The University Of California System and method for treating cardiac arrhythmias with fibroblast cells
EP1509252A4 (en) * 2002-05-08 2006-08-16 Univ California METHODS AND COMPOSITIONS FOR CORRECTION OF HEART CONDUCTION DISORDERS
US20040106896A1 (en) * 2002-11-29 2004-06-03 The Regents Of The University Of California System and method for forming a non-ablative cardiac conduction block
US7627373B2 (en) 2002-11-30 2009-12-01 Cardiac Pacemakers, Inc. Method and apparatus for cell and electrical therapy of living tissue
US7794702B2 (en) * 2003-01-15 2010-09-14 The Trustees Of Columbia University In The City Of New York Mesenchymal stem cells as a vehicle for ion channel transfer in syncytial structures
EP1691747B1 (en) * 2003-11-13 2012-05-23 CardioPolymers, Inc. Control of cardiac arrhythmias by modification of neuronal conduction within fat pads of the heart
US8073538B2 (en) * 2003-11-13 2011-12-06 Cardio Polymers, Inc. Treatment of cardiac arrhythmia by modification of neuronal signaling through fat pads of the heart
US20060128647A1 (en) * 2003-12-24 2006-06-15 Daniel Sigg Novel oligonucleotides and treating cardiac disorders by using the same
US7840263B2 (en) * 2004-02-27 2010-11-23 Cardiac Pacemakers, Inc. Method and apparatus for device controlled gene expression
US20080260705A1 (en) * 2004-03-22 2008-10-23 The Johns Hopkins University Preventing Arrhythmias Associated with Cell Transplantation
US7764995B2 (en) 2004-06-07 2010-07-27 Cardiac Pacemakers, Inc. Method and apparatus to modulate cellular regeneration post myocardial infarct
US20050277124A1 (en) * 2004-06-10 2005-12-15 White Steven M Cardiac conduction system cells and uses thereof
US20050283218A1 (en) * 2004-06-22 2005-12-22 Williams Michael S Implantable chamber for biological induction or enhancement of muscle contraction
WO2006044589A2 (en) * 2004-10-13 2006-04-27 Medtronic, Inc. Cellular and genetic intervention to treat ventricular tachycardia
US8060219B2 (en) 2004-12-20 2011-11-15 Cardiac Pacemakers, Inc. Epicardial patch including isolated extracellular matrix with pacing electrodes
US7981065B2 (en) 2004-12-20 2011-07-19 Cardiac Pacemakers, Inc. Lead electrode incorporating extracellular matrix
US20080069801A1 (en) * 2006-06-13 2008-03-20 Lee Randall J Methods and apparatus for using polymer-based beads and hydrogels for cardiac applications
US20090012413A1 (en) * 2006-09-08 2009-01-08 Sabbah Hani N Cardiac patterning for improving diastolic function
US9375313B2 (en) * 2006-09-08 2016-06-28 The Regents Of The University Of California Intramyocardial patterning for global cardiac resizing and reshaping
US7787949B2 (en) * 2006-10-30 2010-08-31 Medtronic, Inc. Biological pacemaker compositions and systems incorporating interstitial cells of Cajal
CA2682160C (en) * 2007-04-11 2017-04-04 Henry Ford Health System Cardiac repair, resizing and reshaping using the venous system of the heart
US20090117087A1 (en) * 2007-04-13 2009-05-07 Wake Forest University Methods and compositions for printing biologically compatible nanotube composites of autologous tissue
US8574567B2 (en) 2007-05-03 2013-11-05 The Brigham And Women's Hospital, Inc. Multipotent stem cells and uses thereof
WO2008137115A1 (en) 2007-05-03 2008-11-13 The Brigham And Women's Hospital, Inc. Multipotent stem cells and uses thereof
US20110256112A2 (en) * 2008-03-07 2011-10-20 The Trustees Of Columbia University In The City Of New York Compensating for Atrioventricular Block Using a Nucleic Acid Encoding a Sodium Channel or Gap Junction Protein
DK2349292T3 (en) 2008-09-30 2017-06-26 Univ California COMPOSITIONS comprising decellularized extracellular matrix obtained from cardiac tissue
CN102573860A (zh) 2009-10-02 2012-07-11 巴克斯特国际公司 用于治疗肾脏损伤的造血干细胞
JP2013536246A (ja) 2010-08-24 2013-09-19 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 心臓治療のための組成物及び方法
EP2625263B1 (en) 2010-10-08 2020-03-11 Terumo BCT, Inc. Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
WO2013036708A2 (en) 2011-09-07 2013-03-14 The Regents Of The University Of California Compositions and methods for tissue repair with extracellular matrices
EP2817014A2 (en) 2012-02-21 2014-12-31 Baxter International Inc Pharmaceutical composition comprising cd34+ cells
WO2015073913A1 (en) 2013-11-16 2015-05-21 Terumo Bct, Inc. Expanding cells in a bioreactor
EP3102661B1 (en) 2014-02-07 2020-08-05 GOJO Industries, Inc. Compositions and methods with efficacy against spores and other organisms
CN106232800B (zh) 2014-03-25 2020-07-03 泰尔茂比司特公司 介质的被动替代
JP6830059B2 (ja) 2014-09-26 2021-02-17 テルモ ビーシーティー、インコーポレーテッド スケジュール化された細胞フィーディング
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
WO2017205667A1 (en) 2016-05-25 2017-11-30 Terumo Bct, Inc. Cell expansion
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
EP3601521A2 (en) 2017-03-31 2020-02-05 Terumo BCT, Inc. Cell expansion
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
US12234441B2 (en) 2017-03-31 2025-02-25 Terumo Bct, Inc. Cell expansion
IL317969A (en) * 2017-09-20 2025-02-01 Univ California A GENE THERAPY STRATEGY TO RESTORE ELECTRICAL, CARDIAC FUNCTION AND CARDIAC STRUCTURE IN ARRHYTHMOGENIC RIGHT VENTRICULAR CARDIOMYOPATHY
US12098385B2 (en) 2017-09-20 2024-09-24 The Regents Of The University Of California Gene therapy strategy to restore cardiac electrical and structural function in arrhythmogenic right ventricular cardiomyopathy
EP4314244B1 (en) 2021-03-23 2025-07-23 Terumo BCT, Inc. Cell capture and expansion
US12152699B2 (en) 2022-02-28 2024-11-26 Terumo Bct, Inc. Multiple-tube pinch valve assembly

Family Cites Families (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5130141A (en) * 1988-05-24 1992-07-14 Law Peter K Compositions for and methods of treating muscle degeneration and weakness
US5030204A (en) 1988-09-28 1991-07-09 Advanced Cardiovascular Systems, Inc. Guiding catheter with controllable distal tip
US5103821A (en) * 1989-03-06 1992-04-14 Angeion Corporation Method of providing a biological pacemaker
WO1990010471A1 (en) 1989-03-06 1990-09-20 Angeion Corporation Method of providing a biological pacemaker
US5693622A (en) * 1989-03-21 1997-12-02 Vical Incorporated Expression of exogenous polynucleotide sequences cardiac muscle of a mammal
US5087243A (en) 1990-06-18 1992-02-11 Boaz Avitall Myocardial iontophoresis
US5661133B1 (en) * 1991-11-12 1999-06-01 Univ Michigan Collateral blood vessel formation in cardiac muscle by injecting a dna sequence encoding an angiogenic protein
US5709854A (en) * 1993-04-30 1998-01-20 Massachusetts Institute Of Technology Tissue formation by injecting a cell-polymeric solution that gels in vivo
US5551426A (en) 1993-07-14 1996-09-03 Hummel; John D. Intracardiac ablation and mapping catheter
US5602301A (en) * 1993-11-16 1997-02-11 Indiana University Foundation Non-human mammal having a graft and methods of delivering protein to myocardial tissue
US5489294A (en) 1994-02-01 1996-02-06 Medtronic, Inc. Steroid eluting stitch-in chronic cardiac lead
AU4597696A (en) 1994-12-13 1996-07-03 Peter K. Law Myoblast therapy for mammalian diseases
US6129761A (en) * 1995-06-07 2000-10-10 Reprogenesis, Inc. Injectable hydrogel compositions
US5693029A (en) 1995-07-10 1997-12-02 World Medical Manufacturing Corporation Pro-cell intra-cavity therapeutic agent delivery device
US6415178B1 (en) * 1996-09-16 2002-07-02 Impulse Dynamics N.V. Fencing of cardiac muscles
AU2458597A (en) 1996-07-17 1998-02-09 Medtronic, Inc. System for genetically treating cardiac conduction disturbances
CA2266033C (en) 1996-09-10 2005-11-08 Omrix Biopharmaceuticals S.A. Applicator device for applying a multiple component fluid
US5722403A (en) 1996-10-28 1998-03-03 Ep Technologies, Inc. Systems and methods using a porous electrode for ablating and visualizing interior tissue regions
US6059726A (en) * 1996-11-08 2000-05-09 The Regents Of The University Of California Method for locating the atrio-ventricular (AV) junction of the heart and injecting active substances therein
US6271211B1 (en) * 1997-02-13 2001-08-07 Albert Einstein College Of Medicine Of Yeshiva University Gene therapy for regulating penile smooth muscle tone
US6239117B1 (en) * 1997-02-13 2001-05-29 Albert Einstein College Of Medicine Of Yeshiva University Gene therapy for regulating bladder smooth muscle tone
US6086582A (en) 1997-03-13 2000-07-11 Altman; Peter A. Cardiac drug delivery system
IL132103A0 (en) * 1997-04-03 2001-03-19 Eletrofect As Method for introducing pharmaceutical drugs and nucleic acids into skeletal muscle
US6238429B1 (en) * 1997-05-05 2001-05-29 Medtronic, Inc. Biologic cabling
CA2296704C (en) * 1997-07-14 2010-10-19 Osiris Therapeutics, Inc. Cardiac muscle regeneration using mesenchymal stem cells
CA2225185A1 (en) * 1997-08-11 1999-02-11 Peter K. Law Myoblast transfer therapy for relieving pain and for treating behavioral and perceptive abnormalities
CA2304093A1 (en) 1997-09-19 1999-04-01 Reprogenesis, Inc. Improved hydrogel for tissue engineering
US6151525A (en) * 1997-11-07 2000-11-21 Medtronic, Inc. Method and system for myocardial identifier repair
ES2255155T3 (es) * 1998-02-05 2006-06-16 Biosense Webster, Inc. Dispositivo para la administracion intracardiaca de farmacos.
US6360749B1 (en) 1998-10-09 2002-03-26 Swaminathan Jayaraman Modification of properties and geometry of heart tissue to influence heart function
US20010009986A1 (en) * 1999-02-23 2001-07-26 Cordis Webster, Inc. Steerable catheter for detecting and revascularizing ischemic myocardial tissue
CA2402000A1 (en) 2000-03-06 2001-09-13 Tei Biosciences, Inc. Injectable bio-compatible material and methods of use
JP2004504807A (ja) 2000-03-10 2004-02-19 アドヴァンスト　リサーチ　アンド　テクノロジー　インスティチュート、インコーポレイティッド 多分化能細胞および心筋細胞集団、並びに該集団への経路およびその使用
DE10021627B4 (de) 2000-05-04 2009-11-19 Corlife Gbr (Vertretungsberechtigte Gesellschafter: Prof. Dr. Alex Haverich Verfahren zur Herstellung eines vaskularisierten bioartifiziellen Gewebes und zugehöriger Versuchsreaktor
US20020001577A1 (en) * 2000-06-30 2002-01-03 Axel Haverich Use of cells with the ability to generate excitation within a cell preparation
US20020061587A1 (en) * 2000-07-31 2002-05-23 Piero Anversa Methods and compositions for the repair and/or regeneration of damaged myocardium
IL154769A0 (en) 2000-09-06 2003-10-31 Univ Johns Hopkins Cardiac arrhythmia treatment methods
US7294333B1 (en) 2000-10-20 2007-11-13 Genegrafts Ltd. Nucleic acid constructs and cells, and methods utilizing same for modifying the electrophysiological function of excitable tissues
EP1453382A4 (en) 2001-11-08 2005-05-18 Univ California METHOD AND COMPOSITIONS FOR CORRECTING CROSS-BREAKDOWN OF THE HEART
EP1509252A4 (en) 2002-05-08 2006-08-16 Univ California METHODS AND COMPOSITIONS FOR CORRECTION OF HEART CONDUCTION DISORDERS
US20040106896A1 (en) 2002-11-29 2004-06-03 The Regents Of The University Of California System and method for forming a non-ablative cardiac conduction block
US6932804B2 (en) * 2003-01-21 2005-08-23 The Regents Of The University Of California System and method for forming a non-ablative cardiac conduction block
WO2003094855A1 (en) 2002-05-08 2003-11-20 The Regents Of The University Of California System and method for treating cardiac arrhythmias with fibroblast cells
CN1649641A (zh) 2002-05-08 2005-08-03 加利福尼亚大学董事会 形成非切除性心脏传导阻滞的系统和方法
US7317950B2 (en) * 2002-11-16 2008-01-08 The Regents Of The University Of California Cardiac stimulation system with delivery of conductive agent

Also Published As

Publication number Publication date
WO2003039344A2 (en) 2003-05-15
CA2465476A1 (en) 2003-05-15
US7494644B2 (en) 2009-02-24
US7252819B2 (en) 2007-08-07
WO2003039344A3 (en) 2003-12-31
MXPA04004396A (es) 2004-08-11
BR0214018A (pt) 2005-04-19
US20030104568A1 (en) 2003-06-05
AU2002359371A1 (en) 2003-05-19
US20080019953A1 (en) 2008-01-24
JP2005527482A (ja) 2005-09-15
EP1453382A2 (en) 2004-09-08
CN1612691A (zh) 2005-05-04
EP1453382A4 (en) 2005-05-18

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