[go: up one dir, main page]

IL150568A0 - A controlled release oral drug dosage form - Google Patents

A controlled release oral drug dosage form

Info

Publication number
IL150568A0
IL150568A0 IL15056801A IL15056801A IL150568A0 IL 150568 A0 IL150568 A0 IL 150568A0 IL 15056801 A IL15056801 A IL 15056801A IL 15056801 A IL15056801 A IL 15056801A IL 150568 A0 IL150568 A0 IL 150568A0
Authority
IL
Israel
Prior art keywords
dosage form
controlled release
drug
release oral
core
Prior art date
Application number
IL15056801A
Other languages
English (en)
Original Assignee
Depomed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23983134&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL150568(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Depomed Inc filed Critical Depomed Inc
Publication of IL150568A0 publication Critical patent/IL150568A0/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/472Non-condensed isoquinolines, e.g. papaverine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/525Isoalloxazines, e.g. riboflavins, vitamin B2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/60Salicylic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/284Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/2853Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL15056801A 2000-02-04 2001-01-30 A controlled release oral drug dosage form IL150568A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49894500A 2000-02-04 2000-02-04
PCT/US2001/003027 WO2001056544A2 (fr) 2000-02-04 2001-01-30 Forme posologique enveloppe et noyau approchant la liberation d'ordre zero du medicament

Publications (1)

Publication Number Publication Date
IL150568A0 true IL150568A0 (en) 2003-02-12

Family

ID=23983134

Family Applications (2)

Application Number Title Priority Date Filing Date
IL15056801A IL150568A0 (en) 2000-02-04 2001-01-30 A controlled release oral drug dosage form
IL150568A IL150568A (en) 2000-02-04 2002-07-03 Controlled release oral drug dosage form

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL150568A IL150568A (en) 2000-02-04 2002-07-03 Controlled release oral drug dosage form

Country Status (12)

Country Link
US (6) US7736667B2 (fr)
EP (1) EP1251832B1 (fr)
JP (1) JP2003521507A (fr)
AT (1) ATE340563T1 (fr)
AU (1) AU767812B2 (fr)
CA (1) CA2396782A1 (fr)
DE (1) DE60123384T2 (fr)
ES (1) ES2270982T3 (fr)
IL (2) IL150568A0 (fr)
MX (1) MXPA02007254A (fr)
PT (1) PT1251832E (fr)
WO (1) WO2001056544A2 (fr)

Families Citing this family (159)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6878386B1 (en) 1999-04-13 2005-04-12 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising amoxycillin and potassium clavulanate
US6294199B1 (en) 1999-04-13 2001-09-25 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising administering amoxycillin
US7250176B1 (en) 1999-04-13 2007-07-31 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection
DE10031043A1 (de) * 2000-06-26 2002-02-14 Bayer Ag Retardzubereitungen von Chinolonantibiotika und Verfahren zu ihrer Herstellung
US6756057B2 (en) 2000-10-12 2004-06-29 Beecham Pharmaceuticals (Pte) Limited Amoxicillin and potassium clavulanate dosage form
EP1330236A2 (fr) 2000-10-12 2003-07-30 Beecham Pharmaceuticals (Pte) Limited Nouvelle formulation
PL362687A1 (en) * 2001-01-12 2004-11-02 Sun Pharmaceutical Industries Limited Spaced drug delivery system
RU2004108219A (ru) * 2001-09-28 2005-03-10 Сан Фармасьютикл Индастриз Лимитид (In) Лекарственная форма для лечения сахарного диабета
US20030091630A1 (en) * 2001-10-25 2003-05-15 Jenny Louie-Helm Formulation of an erodible, gastric retentive oral dosage form using in vitro disintegration test data
WO2003035039A1 (fr) 2001-10-25 2003-05-01 Depomed, Inc. Traitement utilisant une dose posologique de losartan a retention gastrique
US7612112B2 (en) 2001-10-25 2009-11-03 Depomed, Inc. Methods of treatment using a gastric retained gabapentin dosage
US20060159743A1 (en) * 2001-10-25 2006-07-20 Depomed, Inc. Methods of treating non-nociceptive pain states with gastric retentive gabapentin
CA2409552A1 (fr) 2001-10-25 2003-04-25 Depomed, Inc. Forme posologique orale pouvant etre retenue dans l'estomac dont la liberation est limitee a la partie inferieure du tube digestif
US20070184104A1 (en) * 2001-10-25 2007-08-09 Depomed, Inc. Gastric retentive gabapentin dosage forms and methods for using same
TWI312285B (en) 2001-10-25 2009-07-21 Depomed Inc Methods of treatment using a gastric retained gabapentin dosage
US6682759B2 (en) * 2002-02-01 2004-01-27 Depomed, Inc. Manufacture of oral dosage forms delivering both immediate-release and sustained-release drugs
ES2627842T3 (es) * 2002-02-21 2017-07-31 Valeant Pharmaceuticals Luxembourg S.À.R.L. Formas de dosificación de liberación controlada
US8323692B2 (en) 2002-02-21 2012-12-04 Valeant International Bermuda Controlled release dosage forms
US8128957B1 (en) 2002-02-21 2012-03-06 Valeant International (Barbados) Srl Modified release compositions of at least one form of tramadol
AU2002356419A1 (en) 2002-06-17 2003-12-31 Themis Laboratories Private Limited Multilayer tablets containing thiazolidinedione and biguanides and methods for producing them
US8404717B2 (en) * 2002-10-15 2013-03-26 Celgene Corporation Methods of treating myelodysplastic syndromes using lenalidomide
US11116782B2 (en) 2002-10-15 2021-09-14 Celgene Corporation Methods of treating myelodysplastic syndromes with a combination therapy using lenalidomide and azacitidine
US8404716B2 (en) 2002-10-15 2013-03-26 Celgene Corporation Methods of treating myelodysplastic syndromes with a combination therapy using lenalidomide and azacitidine
AU2004204825B2 (en) 2003-01-13 2007-07-19 Dynogen Pharmaceuticals, Inc. Method of treating functional bowel disorders
KR100772980B1 (ko) * 2004-04-01 2007-11-02 한미약품 주식회사 메트포르민의 경구투여용 서방성 제제
US20050220873A1 (en) * 2004-04-02 2005-10-06 Chien-Hsuan Han Pharmaceutical dosage forms having immediate and controlled release properties that contain a GABAB receptor agonist
US20050226927A1 (en) * 2004-04-02 2005-10-13 Impax Laboratories, Inc. Pharmaceutical dosage forms having immediate release and/or controlled release properties that contain a GABAB receptor agonist
US8007827B2 (en) * 2004-04-02 2011-08-30 Impax Laboratories, Inc. Pharmaceutical dosage forms having immediate release and/or controlled release properties
CN100459982C (zh) * 2004-08-30 2009-02-11 鲁南制药集团股份有限公司 去氧氟尿苷的分散片剂型
KR100760430B1 (ko) * 2004-12-31 2007-10-04 한미약품 주식회사 당뇨병 치료제의 경구 투여용 서방성 복합 제제 및 이의제조 방법
PT1919466E (pt) 2005-07-11 2012-05-21 Cortria Corp Formulações para tratamento de anormalidades de lipoproteína compreendendo uma estatina e um derivado de metilnicotinamida
US8728521B2 (en) * 2005-12-27 2014-05-20 Hemant N. Joshi Physically/molecularly distributed and/or chemically bound medicaments in empty, hard capsule shells
US20070148227A1 (en) * 2005-12-27 2007-06-28 Hemant Joshi Physically/molecularly distributed and/or chemically bound medicaments in capsule shells
US20090176882A1 (en) * 2008-12-09 2009-07-09 Depomed, Inc. Gastric retentive gabapentin dosage forms and methods for using same
EP2428204A3 (fr) * 2006-12-07 2012-07-04 Schering Corporation Formulation de matrice sensible au pH
CN101677956A (zh) * 2007-06-11 2010-03-24 阿普尔顿纸张公司 包含有益剂的递送颗粒
EP2192892A2 (fr) * 2007-07-27 2010-06-09 Depomed, Inc. Formes médicamenteuses de rétention gastrique pulsatile
US8329750B2 (en) * 2008-02-11 2012-12-11 Depomed, Inc. Methods for treating vasomotor symptoms using GABA analogs in a gastric retentive dosage form
US8372432B2 (en) * 2008-03-11 2013-02-12 Depomed, Inc. Gastric retentive extended-release dosage forms comprising combinations of a non-opioid analgesic and an opioid analgesic
JP5607550B2 (ja) 2008-03-11 2014-10-15 ディポメド,インコーポレイティド 非オピオイド鎮痛剤及びオピオイド鎮痛剤の組合せを含む胃保持性持続放出剤形
LT3692983T (lt) 2008-05-15 2021-11-10 Celgene Corporation Citidino analogų peroralinės kompozicijos ir jų naudojimo būdai
ES2740360T3 (es) 2008-08-15 2020-02-05 Assertio Therapeutics Inc Composiciones farmacéuticas de retención gástrica para el tratamiento y la prevención de trastornos del SNC
WO2010129686A1 (fr) 2009-05-05 2010-11-11 Vapogenix, Inc. Nouvelles formulations d'anesthésiques volatiles et procédés d'utilisation pour réduire l'inflammation
AU2010286354A1 (en) * 2009-08-31 2012-04-19 Depomed, Inc. Gastric retentive pharmaceutical compositions for immediate and extended release of acetaminophen
US20110052700A1 (en) * 2009-08-31 2011-03-03 Depomed, Inc. Gastric retentive pharmaceutical compositions for immediate and extended release of levosulpiride
US20110104272A1 (en) * 2009-11-05 2011-05-05 Depomed, Inc. Gastric retentive extended-release dosage forms comprising combinations of acetaminophen and phenylephrine
US20110104273A1 (en) * 2009-11-05 2011-05-05 Depomed, Inc. Gastric retentive pharmaceutical compositions for immediate and extended release of phenylephrine
US20110135728A1 (en) * 2009-12-08 2011-06-09 Miller Jennifer L Gastric retentive pharmaceutical compositions for extended release of polypeptides
US8597681B2 (en) 2009-12-22 2013-12-03 Mallinckrodt Llc Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans
US9198861B2 (en) 2009-12-22 2015-12-01 Mallinckrodt Llc Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans
EP2389934A1 (fr) * 2010-05-25 2011-11-30 Sanovel Ilac Sanayi ve Ticaret A.S. Formulations de prégabaline en comprimé à libération prolongée
CN103347517B (zh) 2010-08-11 2018-10-02 德雷克塞尔大学 治疗帕金森病中运动障碍的d3多巴胺受体激动剂
WO2012050922A2 (fr) 2010-09-28 2012-04-19 Depomed, Inc. Formes pharmaceutiques à rétention gastrique pour la libération prolongée d'acamprosate dans le tractus gastro-intestinal supérieur
JP6076913B2 (ja) 2010-12-07 2017-02-08 ドレクセル ユニバーシティ 癌からの転移を阻害する方法
US9532977B2 (en) 2010-12-16 2017-01-03 Celgene Corporation Controlled release oral dosage forms of poorly soluble drugs and uses thereof
ES2753198T5 (es) 2010-12-16 2023-05-31 Amgen Europe Gmbh Formas farmacéuticas orales de liberación controlada de fármacos poco solubles y sus usos
KR101647267B1 (ko) 2010-12-22 2016-08-09 퍼듀 퍼머 엘피 케이싱된 탬퍼 저항성 제어 방출 투여 형태
PH12013501345A1 (en) 2010-12-23 2022-10-24 Purdue Pharma Lp Tamper resistant solid oral dosage forms
US8476221B2 (en) 2011-03-18 2013-07-02 Halimed Pharmaceuticals, Inc. Methods and compositions for the treatment of metabolic disorders
HRP20150835T1 (hr) * 2011-03-25 2015-09-11 Purdue Pharma L.P. Farmaceutski oblici doziranja s kontroliranim oslobađanjem
US9050335B1 (en) 2011-05-17 2015-06-09 Mallinckrodt Llc Pharmaceutical compositions for extended release of oxycodone and acetaminophen resulting in a quick onset and prolonged period of analgesia
US8741885B1 (en) 2011-05-17 2014-06-03 Mallinckrodt Llc Gastric retentive extended release pharmaceutical compositions
US8858963B1 (en) 2011-05-17 2014-10-14 Mallinckrodt Llc Tamper resistant composition comprising hydrocodone and acetaminophen for rapid onset and extended duration of analgesia
DE102011051653A1 (de) 2011-07-07 2013-01-10 Lts Lohmann Therapie-Systeme Ag Quellfähige Manteltablette
AU2012318239B2 (en) 2011-11-01 2015-07-09 Celgene Corporation Methods for treating cancers using oral formulations of cytidine analogs
US20130143867A1 (en) 2011-12-02 2013-06-06 Sychroneuron Inc. Acamprosate formulations, methods of using the same, and combinations comprising the same
KR20190007106A (ko) 2011-12-21 2019-01-21 노비라 테라퓨틱스, 인코포레이티드 B형 간염의 항바이러스성 제제
US20140343452A1 (en) * 2011-12-21 2014-11-20 Eatlittle Inc. Pseudobezoar-Based Intraluminal Gastrointestinal Cleansing and Biospy
WO2014015157A2 (fr) 2012-07-19 2014-01-23 Philadelphia Health & Education Corporation Nouveaux ligands du récepteur sigma et procédés de modulation de l'homéostase de protéine cellulaire à l'aide de ceux-ci
EP3378472A1 (fr) 2012-08-09 2018-09-26 Dynamis Therapeutics, Inc. Combinaisons avec de la méglumine
PT2941233T (pt) 2013-01-07 2020-11-13 Univ Pennsylvania Composições e métodos para tratar linfoma cutâneo de células t
US8652527B1 (en) 2013-03-13 2014-02-18 Upsher-Smith Laboratories, Inc Extended-release topiramate capsules
US10751287B2 (en) 2013-03-15 2020-08-25 Purdue Pharma L.P. Tamper resistant pharmaceutical formulations
US9101545B2 (en) 2013-03-15 2015-08-11 Upsher-Smith Laboratories, Inc. Extended-release topiramate capsules
CA2914365C (fr) 2013-06-05 2022-03-15 Synchroneuron, Inc. Formulations d'acamprosate, procedes d'utilisation de celles-ci, et combinaisons comprenant celles-ci
EP3613861A1 (fr) 2013-07-02 2020-02-26 EcoPlanet Environmental LLC Formulations de composés organiques volatils dotés d'une activité antimicrobienne
GB201311888D0 (en) 2013-07-03 2013-08-14 Glaxosmithkline Ip Dev Ltd Novel compounds
GB201311891D0 (en) 2013-07-03 2013-08-14 Glaxosmithkline Ip Dev Ltd Novel compound
JP6932506B2 (ja) 2013-11-26 2021-09-08 イエール ユニバーシティ 細胞透過組成物およびそれを用いる方法
EP3079692A4 (fr) 2013-12-09 2017-10-18 Thomas Jefferson University Nouveau procédé de traitement d'une maladie neurodégénérative chez un mammifère qui en a besoin
WO2015157262A1 (fr) 2014-04-07 2015-10-15 Women & Infants Hospital Of Rhode Island Nouveux dérivés de 7-déshydrocholestérol et procédés les utilisant
US20180228907A1 (en) 2014-04-14 2018-08-16 Arvinas, Inc. Cereblon ligands and bifunctional compounds comprising the same
RU2016151697A (ru) 2014-06-02 2018-07-10 Тева Фармасьютикал Индастриз Лтд. Расправляемая удерживаемая в желудке лекарственная форма
US20150359810A1 (en) 2014-06-17 2015-12-17 Celgene Corporation Methods for treating epstein-barr virus (ebv) associated cancers using oral formulations of 5-azacytidine
WO2016003870A1 (fr) 2014-07-01 2016-01-07 Tntgamble, Inc. Comprimés probiotiques bi-couche à double libération
CN106714809A (zh) 2014-08-20 2017-05-24 耶鲁大学 对治疗或预防肝脏疾病或障碍和促进体重减轻有用的新型组合物和方法
FI3182996T3 (fi) 2014-08-22 2023-03-28 Celgene Corp Menetelmiä multippelin myelooman hoitamiseksi immuunivastetta muuntavilla yhdisteillä yhdistelmässä vasta-aineiden kanssa
WO2016033295A1 (fr) * 2014-08-27 2016-03-03 The Regents Of The University Of Colorado, A Body Corporate Dispositifs médicaux à base de matrice polymère multicouche
US10987328B2 (en) 2015-02-20 2021-04-27 Osmotica Kereskedelmi Es Szolgaltato Kft Controlled release dosage form
EP3258916A1 (fr) 2015-02-20 2017-12-27 Osmotica Kereskedelmi ES Szolgaltato KFT Forme galénique à libération contrôlée administrée par voie orale d'agoniste du récepteur du gaba présentant une pharmacocinétique améliorée
US10300032B2 (en) 2015-02-20 2019-05-28 Osmotica Kereskedelmi Es Szolgaltato Kft Controlled release dosage form
US10172800B2 (en) 2015-02-20 2019-01-08 Osmotica Kereskedelmi Es Szolgaltato Kft Controlled release dosage form with enhanced pharmacokinetics
WO2016182968A1 (fr) 2015-05-08 2016-11-17 Brown University Nouveaux analogues de syringoline et procédés de fabrication et d'utilisation de ceux-ci
JP6995627B2 (ja) 2015-05-19 2022-02-04 イエール ユニバーシティ 病的石灰化状態を治療するための組成物およびそれを使用する方法
WO2016201288A1 (fr) 2015-06-12 2016-12-15 Brown University Nouveaux composés antibactériens et procédés de préparation et d'utilisation de ceux-ci
US11000481B2 (en) 2015-06-26 2021-05-11 Korea United Pharm. Inc. Composite preparation of mosapride and rabeprazole
KR102207539B1 (ko) 2015-06-30 2021-01-26 네우라드 리미티드 신규한 호흡 제어 조절 화합물, 및 그의 제조 및 사용 방법
BR112018002991A2 (pt) * 2015-08-18 2018-09-25 Basf Se microcápsula, processo para produzir a microcápsula, dispersão aquosa e método de controle
HUE057263T2 (hu) 2015-10-15 2022-04-28 Servier Lab Kombinációs terápia rosszindulató betegségek kezelésére
AU2016340098B2 (en) 2015-10-15 2022-06-02 Celgene Corporation Combination therapy for treating malignancies
WO2017066599A1 (fr) 2015-10-15 2017-04-20 Agios Pharmaceuticals, Inc. Polythérapie pour le traitement des pathologies malignes
WO2017075145A1 (fr) 2015-10-28 2017-05-04 Yale University Amides de quinoléine et leurs méthodes d'utilisation
EP3373916A1 (fr) 2015-11-11 2018-09-19 Celgene Corporation Formes pharmaceutiques orales à libération contrôlée de médicaments faiblement solubles et leurs utilisations
JP2018537093A (ja) 2015-11-20 2018-12-20 イエール ユニバーシティ 異所性石灰化障害を治療するための組成物およびそれを使用する方法
ES2905915T3 (es) 2015-12-04 2022-04-12 Servier Lab Procedimientos de tratamiento de neoplasias malignas
JP6930991B2 (ja) 2016-02-26 2021-09-01 セルジーン コーポレイション 血液学的悪性腫瘍及び固形腫瘍の治療のためのidh2阻害剤
EP3448369B1 (fr) 2016-04-29 2025-06-25 The Regents of The University of Colorado, A Body Corporate Inhibition ou dégradation de hdac11 pour le traitement de l'obésité, de l'hyperlipidémie, du diabète de type ii, du syndrome métabolique ou de la résistance à l'insuline, et pour favoriser la perte de poids et/ou améliorer ou prévenir la prise de poids
US20210330599A1 (en) 2016-08-01 2021-10-28 University Of Rochester Nanoparticles for Controlled Release of Anti-Biofilm Agents and Methods of Use
EP3493809B1 (fr) 2016-08-03 2023-08-23 Celgene Corporation Enasidenib pour le traitement du syndrome myélodysplasique
US11390859B2 (en) 2016-08-05 2022-07-19 Yale University Compositions and methods for stroke prevention in pediatric sickle cell anemia patients
AU2017321791B2 (en) 2016-09-01 2022-03-24 Mebias Discovery, Inc. Substituted ureas and methods of making and using same
AU2017353986B2 (en) 2016-11-07 2021-08-19 Arbutus Biopharma Corporation Substituted pyridinone-containing tricyclic compounds, and methods using same
US10737079B2 (en) 2016-12-02 2020-08-11 Clexio Biosciences Ltd. Gastric residence system
US10941126B2 (en) 2017-01-19 2021-03-09 Temple University-Of The Commonwealth System Of Higher Education Bridged bicycloalkyl-substituted aminothiazoles and their methods of use
EP3601216B1 (fr) 2017-03-21 2023-10-25 Arbutus Biopharma Corporation Dihydroindène-4-carboxamides substitués, leurs analogues et procédés d'utilisation correspondant pour le traitement de l'infection au virus hepatitis b
US11166953B2 (en) 2017-04-17 2021-11-09 Yale University Compounds, compositions and methods of treating or preventing acute lung injury
US11229653B2 (en) 2017-05-05 2022-01-25 Celgene Corporation Methods of treatment of myeloproliferative neoplasm
ES2928071T3 (es) 2017-06-16 2022-11-15 Amneal Complex Products Res Llc Formas de dosificación gastrorretentiva para el suministro sostenido de fármacos
US10987311B2 (en) 2017-06-16 2021-04-27 Kashiv Specialty Pharmaceuticals, Llc Extended release compositions comprising pyridostigmine
US10588863B2 (en) 2017-06-16 2020-03-17 Kashiv Biosciences, Llc Extended release compositions comprising pyridostigmine
WO2019023621A1 (fr) 2017-07-28 2019-01-31 Yale University Médicaments anticancéreux et leurs procédés de fabrication et d'utilisation
KR20200072478A (ko) 2017-09-08 2020-06-22 더 리전츠 오브 더 유니버시티 오브 콜로라도, 어 바디 코퍼레이트 Her-구동된 약물-내성암의 치료 또는 예방을 위한 화합물, 조성물 및 방법
JP7293209B2 (ja) * 2017-10-20 2023-06-19 パーデュー、ファーマ、リミテッド、パートナーシップ 医薬剤形
EP3716985A1 (fr) 2017-11-27 2020-10-07 The U.S.A. As Represented By The Secretary, Department Of Health And Human Services Composés, compositions et méthodes pour le traitement et/ou la prévention d'une maladie parodontale
US11547839B2 (en) 2017-12-04 2023-01-10 Clexio Biosciences Ltd. Long acting gastric residence system
WO2019125184A1 (fr) 2017-12-19 2019-06-27 Auckland Uniservices Limited Utilisation de biomarqueur en thérapie du cancer
EP3743060A4 (fr) 2018-01-24 2021-11-03 The Rockefeller University Composés antibactériens, compositions associées, et leurs méthodes d'utilisation
BR112020024048A2 (pt) 2018-05-25 2021-02-17 Temple University-Of The Commonwealth System Of Higher Education composição, e, métodos para descolonizar um organismo microbiano, para destruir ou interromper ou inibir ou reduzir a formação de biofilme de um organismo microbiano e para tratar uma infecção microbiana em um indivíduo.
US11091473B2 (en) 2018-05-29 2021-08-17 Acadia Pharmaceuticals Inc. Compounds for pain treatment, compositions comprising same, and methods of using same
EP4056172A1 (fr) 2018-06-18 2022-09-14 Amneal Complex Products Research LLC Compositions à libération prolongée comprenant de la pyridostigmine
TWI826492B (zh) 2018-07-27 2023-12-21 加拿大商愛彼特生物製藥公司 經取代四氫環戊[c]吡咯、經取代二氫吡咯,其類似物及使用其之方法
MX2021001877A (es) 2018-08-17 2021-07-15 Univ Pennsylvania Composiciones y métodos para el tratamiento de lesión pulmonar aguda.
WO2020074944A1 (fr) 2018-10-11 2020-04-16 Sanifit Therapeutics S.A. Phosphates d'inositol pour le traitement de la calcification ectopique
WO2020081762A1 (fr) 2018-10-19 2020-04-23 Temple University-Of The Commonwealth System Of Higher Education Formes de dosages de médicaments résistantes à l'altération et procédés destinés à les réaliser et les utiliser
US20220017489A1 (en) 2018-11-02 2022-01-20 Celgene Corporation Solid dispersions for treatment of cancer
WO2020092906A1 (fr) 2018-11-02 2020-05-07 Celgene Corporation Co-cristaux de 2-méthyl-1-[(4-[6-(trifluorométhyl)pyridin-2-yl]-6-{[2-(trifluorométhyl) pyridin-4-yl]amino}-1,3,5-triazin-2-yl) amino] propan-2-ol, compositions et procédés d'utilisation de ceux-ci
WO2020092894A1 (fr) 2018-11-02 2020-05-07 Celgene Corporation Formes solides de 2-méthyl-1-[(4-[6-(trifluorométhyl)pyridin-2-yl]-6-{[2-(trifluorométhyl)pyridin-4-yl]amino}-1,3,5-triazin-2-yl)amino]propan-2-ol
TW202415643A (zh) 2018-12-12 2024-04-16 加拿大商愛彼特生物製藥公司 經取代之芳基甲基脲類及雜芳基甲基脲類、其類似物及其使用方法
KR20210148078A (ko) 2019-01-30 2021-12-07 사니핏 테라퓨틱스 에스.에이. 조직 관류 증가에 사용하기 위한 이노시톨 포스페이트 화합물
US20200246316A1 (en) 2019-02-01 2020-08-06 Cersci Therapeutics, Inc. Methods of treating post-surgical pain with a thiazoline anti-hyperalgesic agent
US20200246317A1 (en) 2019-02-01 2020-08-06 Cersci Therapeutics, Inc. Methods of treating diabetic neuropathy with a thiazoline anti-hyperalgesic agent
WO2020227603A1 (fr) 2019-05-09 2020-11-12 The Feinstein Institutes For Medical Research Antagoniste de hmgb1
JP2022538767A (ja) 2019-06-12 2022-09-06 ザ ウィスター インスティテュート アセチルCoAシンテターゼ2(ACSS2)阻害剤およびそれを使用する方法
US11555010B2 (en) 2019-07-25 2023-01-17 Brown University Diamide antimicrobial agents
EP3818983A1 (fr) 2019-11-11 2021-05-12 Sanifit Therapeutics S.A. Composés de phosphate d'inositol pour une utilisation dans le traitement, l'inhibition de la progression ou la prévention de la calcification cardiovasculaire
WO2021127456A1 (fr) 2019-12-19 2021-06-24 Rain Therapeutics Inc. Procédés d'inhibition de protéines réceptrices du facteur de croissance épidermique
BR112022024958A2 (pt) 2020-06-09 2022-12-27 Inozyme Pharma Inc Proteínas enpp1 solúveis e usos das mesmas
CN112034057B (zh) * 2020-08-16 2022-04-01 江苏正大清江制药有限公司 一种测定头孢呋辛酯原料中高分子聚合物的方法
EP4015494A1 (fr) 2020-12-15 2022-06-22 Sanifit Therapeutics S.A. Procédés de préparation de sels solubles de phosphates d'inositol
EP4036097A1 (fr) 2021-01-29 2022-08-03 Sanifit Therapeutics S.A. Composés dérivés substitués de l'ip4-4,6
TW202412815A (zh) 2022-07-29 2024-04-01 西班牙商薩尼菲特治療公司 Ip5經取代化合物
JP2025525092A (ja) 2022-07-29 2025-08-01 サニフィット・セラピューティクス・ソシエダッド・アノニマ 異所性石灰化の治療、進行の阻害、および予防に使用するためのip4-4,6置換誘導体化合物
KR20250059489A (ko) 2022-09-06 2025-05-02 하다지트 메디칼 리서치 써비시즈 앤드 디벨롭먼트 리미티드 조현병 및 기타 신경정신장애 및 신경학적 장애의 치료를 위한 환각물질 포함 조합물
TW202513071A (zh) 2023-08-14 2025-04-01 以色列商琉璃藥品 (1991) 有限公司 Gal475組合物及其使用方法
WO2025099725A1 (fr) 2023-11-09 2025-05-15 Hadasit Medical Research Services And Development Ltd. Conjugués et leurs utilisations
WO2025162971A1 (fr) 2024-01-31 2025-08-07 Sanifit Therapeutics, S.A. Composés ip5 substitués destinés à être utilisés dans le traitement, l'inhibition de la progression et la prévention de la calcification ectopique
WO2025217096A1 (fr) 2024-04-08 2025-10-16 University Of Rochester Inhibiteurs de la kinase 2 à répétition riche en leucine (lrrk2) et leurs utilisations médicales
WO2025217094A1 (fr) 2024-04-08 2025-10-16 University Of Rochester Dégradeurs protak de de la kinase associée au récepteur de l'interleukine (irak) et leur utilisation médicale
WO2025217379A1 (fr) 2024-04-10 2025-10-16 University Of Rochester Traitement médicamenteux pour la dégénérescence maculaire

Family Cites Families (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3538214A (en) 1969-04-22 1970-11-03 Merck & Co Inc Controlled release medicinal tablets
ZA722664B (en) 1971-05-18 1973-01-31 Smith Kline French Lab Lyered bolus for animal husbandry providing for immediate and sustained release of medicament
CH582002A5 (fr) * 1972-06-09 1976-11-30 Purdue Research Foundation
US4088798A (en) * 1975-11-11 1978-05-09 Sandoz, Inc. Methods for the preparation of controlled gastric residence time medicament formulations
US4207890A (en) 1977-01-04 1980-06-17 Mcneilab, Inc. Drug-dispensing device and method
US4256108A (en) 1977-04-07 1981-03-17 Alza Corporation Microporous-semipermeable laminated osmotic system
US4200098A (en) 1978-10-23 1980-04-29 Alza Corporation Osmotic system with distribution zone for dispensing beneficial agent
US4309406A (en) * 1979-07-10 1982-01-05 American Home Products Corporation Sustained release pharmaceutical compositions
JPS58134019A (ja) 1982-02-05 1983-08-10 Ono Pharmaceut Co Ltd プロスタグランジン含有持続放出型三層状フイルム製剤及びその製造方法
US4629620A (en) * 1984-09-05 1986-12-16 Ab Ferrosan Membrane-coated sustained-release tablets and method
US4892742A (en) * 1985-11-18 1990-01-09 Hoffmann-La Roche Inc. Controlled release compositions with zero order release
IT1188212B (it) 1985-12-20 1988-01-07 Paolo Colombo Sistema per il rilascio a velocita' controllata di sostanze attive
US4867969A (en) 1986-02-07 1989-09-19 Alza Corporation Hydrogel formulation for administering non-steroidal drugs
JPS62195323A (ja) 1986-02-24 1987-08-28 Eisai Co Ltd 胃内滞留型粒子
US4756911A (en) * 1986-04-16 1988-07-12 E. R. Squibb & Sons, Inc. Controlled release formulation
US4816264A (en) * 1986-06-06 1989-03-28 Warner-Lambert Company Sustained release formulations
US4789549A (en) * 1987-03-09 1988-12-06 Warner-Lambert Company Sustained release dosage forms
US4891223A (en) * 1987-09-03 1990-01-02 Air Products And Chemicals, Inc. Controlled release delivery coating formulation for bioactive substances
IL87710A (en) 1987-09-18 1992-06-21 Ciba Geigy Ag Covered floating retard form for controlled release in gastric juice
US5190760A (en) * 1989-07-08 1993-03-02 Coopers Animal Health Limited Solid pharmaceutical composition
IT1237904B (it) 1989-12-14 1993-06-18 Ubaldo Conte Compresse a rilascio a velocita' controllata delle sostanze attive
AT397345B (de) * 1990-04-04 1994-03-25 Chemiefaser Lenzing Ag Pharmazeutisches präparat mit verzögerter wirkstofffreisetzung auf basis von hemicellulosen
ATE118345T1 (de) * 1990-08-07 1995-03-15 Pfizer Verwendung von interfacial polymerisierten membranen in abgabevorrichtungen.
IT1251153B (it) * 1991-08-06 1995-05-04 Vectorpharma Int Composizioni farmaceutiche solide per somministrazione orale aventi proungata residenza gastrica
US5512299A (en) 1992-03-30 1996-04-30 Alza Corporation Method of treating oral inflammatory disease
US5260068A (en) 1992-05-04 1993-11-09 Anda Sr Pharmaceuticals Inc. Multiparticulate pulsatile drug delivery system
IT1255522B (it) 1992-09-24 1995-11-09 Ubaldo Conte Compressa per impiego terapeutico atta a cedere una o piu' sostanze attive con differenti velocita'
IT1256393B (it) * 1992-11-17 1995-12-04 Inverni Della Beffa Spa Forme matriciali multistrato per il rilascio controllato di principi attivi
US5391378A (en) * 1993-02-22 1995-02-21 Elizabeth-Hata International, Inc. Two-part medicinal tablet and method of manufacture
EP0711146B1 (fr) * 1993-07-22 2000-09-06 Pfizer Inc. Dispositif osmotique dont le revetement est permeable a la vapeur
US5415688A (en) 1993-09-20 1995-05-16 Ameron, Inc. Water-borne polysiloxane/polysilicate binder
US5500227A (en) * 1993-11-23 1996-03-19 Euro-Celtique, S.A. Immediate release tablet cores of insoluble drugs having sustained-release coating
IT1265240B1 (it) 1993-11-30 1996-10-31 Ekita Investments Nv Compressa farmaceutica a rilascio controllato, di forma lenticolare
HU213407B (en) 1993-12-09 1997-06-30 Egyt Gyogyszervegyeszeti Gyar Process for producing tablet with diffusive-osmotic release
US5458888A (en) * 1994-03-02 1995-10-17 Andrx Pharmaceuticals, Inc. Controlled release tablet formulation
US5458887A (en) * 1994-03-02 1995-10-17 Andrx Pharmaceuticals, Inc. Controlled release tablet formulation
US5464633A (en) * 1994-05-24 1995-11-07 Jagotec Ag Pharmaceutical tablets releasing the active substance after a definite period of time
DE4432757A1 (de) * 1994-09-14 1996-03-21 Boehringer Mannheim Gmbh Pharmazeutische Zubereitung enthaltend Metformin und Verfahren zu deren Herstellung
US5945125A (en) 1995-02-28 1999-08-31 Temple University Controlled release tablet
MY113429A (en) 1995-02-28 2002-02-28 Univ Temple Controlled release tablet containing swellable polyethylene oxide
US5736159A (en) * 1995-04-28 1998-04-07 Andrx Pharmaceuticals, Inc. Controlled release formulation for water insoluble drugs in which a passageway is formed in situ
US5654005A (en) * 1995-06-07 1997-08-05 Andrx Pharmaceuticals, Inc. Controlled release formulation having a preformed passageway
JP3220373B2 (ja) * 1995-11-28 2001-10-22 バイエル薬品株式会社 持続性ニフエジピン製剤
US5840332A (en) * 1996-01-18 1998-11-24 Perio Products Ltd. Gastrointestinal drug delivery system
US5783212A (en) * 1996-02-02 1998-07-21 Temple University--of the Commonwealth System of Higher Education Controlled release drug delivery system
US6096339A (en) * 1997-04-04 2000-08-01 Alza Corporation Dosage form, process of making and using same
MXPA99001958A (es) * 1996-08-29 2005-09-08 Sanofi Aventis Tableta con liberacion controlada de clorhidrato de alfuzosina.
US5972389A (en) * 1996-09-19 1999-10-26 Depomed, Inc. Gastric-retentive, oral drug dosage forms for the controlled-release of sparingly soluble drugs and insoluble matter
CZ297098B6 (cs) 1997-01-14 2006-09-13 Lts Lohmann Therapie-Systeme Gmbh Prípravek pro kontrolované uvolnování úcinných látek v gastrointestinálním traktu a zpusob jeho výroby
US5891474A (en) * 1997-01-29 1999-04-06 Poli Industria Chimica, S.P.A. Time-specific controlled release dosage formulations and method of preparing same
AU729529B2 (en) * 1997-06-06 2001-02-01 Depomed, Inc. Gastric-retentive oral drug dosage forms for controlled release of highly soluble drugs
US6120803A (en) * 1997-08-11 2000-09-19 Alza Corporation Prolonged release active agent dosage form adapted for gastric retention
US5916595A (en) * 1997-12-12 1999-06-29 Andrx Pharmaceutials, Inc. HMG co-reductase inhibitor
FR2772615B1 (fr) * 1997-12-23 2002-06-14 Lipha Comprime multicouche pour la liberation instantanee puis prolongee de substances actives
CA2220038A1 (fr) * 1998-01-05 1999-07-05 Amina Odidi Dispositif pour la livraison de forte dose de substance pharmaceutique, nutraceutique, agricole, biologique et chimique
ID26082A (id) * 1998-03-19 2000-11-23 Briston Myers Squib Company Sistem pengiriman lepas terkendali dwifasa untuk zat-zat farmasi kelarutan tinggi dan metodenya
US6099859A (en) * 1998-03-20 2000-08-08 Andrx Pharmaceuticals, Inc. Controlled release oral tablet having a unitary core
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
US20030091630A1 (en) * 2001-10-25 2003-05-15 Jenny Louie-Helm Formulation of an erodible, gastric retentive oral dosage form using in vitro disintegration test data

Also Published As

Publication number Publication date
US20170172930A1 (en) 2017-06-22
AU767812B2 (en) 2003-11-27
US20110236485A1 (en) 2011-09-29
CA2396782A1 (fr) 2001-08-09
US20030104062A1 (en) 2003-06-05
EP1251832A2 (fr) 2002-10-30
IL150568A (en) 2007-12-03
US20130164377A1 (en) 2013-06-27
ES2270982T3 (es) 2007-04-16
WO2001056544A2 (fr) 2001-08-09
US8043630B2 (en) 2011-10-25
HK1050493A1 (en) 2003-06-27
US9597338B2 (en) 2017-03-21
MXPA02007254A (es) 2002-12-09
US20150182541A1 (en) 2015-07-02
AU3466101A (en) 2001-08-14
US20100272808A1 (en) 2010-10-28
JP2003521507A (ja) 2003-07-15
US8329215B2 (en) 2012-12-11
US7736667B2 (en) 2010-06-15
ATE340563T1 (de) 2006-10-15
PT1251832E (pt) 2007-01-31
WO2001056544A3 (fr) 2002-05-02
EP1251832B1 (fr) 2006-09-27
US8945619B2 (en) 2015-02-03
DE60123384D1 (de) 2006-11-09
DE60123384T2 (de) 2007-08-02

Similar Documents

Publication Publication Date Title
IL150568A0 (en) A controlled release oral drug dosage form
IL153464A0 (en) A controlled release oral drug dosage form
AP2002002410A0 (en) Hydrodynamically Balancing Oral Drug Delivery System
TW200518784A (en) Azithromycin dosage forms with reduced side effects
DE59707812D1 (de) Opioidantagonisthaltige galenische formulierung
DK1246622T3 (da) Nye substituerede benzimidazol dosisformer og metoder til deres anvendelse
ES2172239T3 (es) Sistema osmotico de liberacion de farmacos.
DE50203456D1 (de) Deuterierte 3-piperidinopropiophenone sowie diese verbindungen enthaltende arzneimittel
AP2003002763A0 (en) Controlled release formulations for oral administration
NO20101070L (no) Fremgangsmate til dosering av et medikament, samt doseringsform
EA200700158A1 (ru) Лекарственные формы с ядром таблетки, покрытым энтеросолюбильной оболочкой
HUP0203148A2 (hu) Mirtazapint tartalmazó orálisan dezintegrálódó készítmény
WO2006040779A3 (fr) Formule à matrice flottante gastrique à libération contrôlée contenant la substance imatinib
SG145717A1 (en) Composition for releasing a weak base for an extended period of time
IS6532A (is) Lyfjaform til stýrðrar losunar á síprófloxasíni með inntöku um munn einu sinni á dag
IL157539A0 (en) A stable pharmaceutical formulation comprising torsemide modification ii
NO20060313L (no) Saquinavirmesylat oral doseringsform
WO2002092565A3 (fr) Composes
TR200301553A1 (tr) İrbesartan etken maddesi içeren yeni oral farmasötik formülasyonlar
DE602005008128D1 (de) Cytisinehaltiges Arzneimittel
WO2002067894A3 (fr) Comprimes a dissolution rapide d'inhibiteurs de l'enzyme cyclooxygenase-2
AP2218A (en) Azithromycin dosage forms with reduced side effects
WO2003037301A3 (fr) Procedes et formes galeniques pour obtenir une meilleure biodisponibilite d'agents therapeutiques
MY145885A (en) Controlled release formulations for oral administration

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed