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IL159900A0 - Cysteine mutants and methods for detecting ligand binding to biological molecules - Google Patents

Cysteine mutants and methods for detecting ligand binding to biological molecules

Info

Publication number
IL159900A0
IL159900A0 IL15990002A IL15990002A IL159900A0 IL 159900 A0 IL159900 A0 IL 159900A0 IL 15990002 A IL15990002 A IL 15990002A IL 15990002 A IL15990002 A IL 15990002A IL 159900 A0 IL159900 A0 IL 159900A0
Authority
IL
Israel
Prior art keywords
methods
ligand binding
biological molecules
cysteine mutants
detecting ligand
Prior art date
Application number
IL15990002A
Original Assignee
Sunesis Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/981,547 external-priority patent/US20020022233A1/en
Priority claimed from US09/990,421 external-priority patent/US6919178B2/en
Priority claimed from US10/121,216 external-priority patent/US6998233B2/en
Application filed by Sunesis Pharmaceuticals Inc filed Critical Sunesis Pharmaceuticals Inc
Publication of IL159900A0 publication Critical patent/IL159900A0/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
IL15990002A 2001-08-07 2002-08-05 Cysteine mutants and methods for detecting ligand binding to biological molecules IL159900A0 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US31072501P 2001-08-07 2001-08-07
US09/981,547 US20020022233A1 (en) 1998-06-26 2001-10-17 Methods for rapidly identifying small organic molecule ligands for binding to biological target molecules
US09/990,421 US6919178B2 (en) 2000-11-21 2001-11-21 Extended tethering approach for rapid identification of ligands
US10/121,216 US6998233B2 (en) 1998-06-26 2002-04-10 Methods for ligand discovery
PCT/US2002/024921 WO2003014308A2 (en) 2001-08-07 2002-08-05 Cysteine mutants and methods for detecting ligand binding to biological molecules

Publications (1)

Publication Number Publication Date
IL159900A0 true IL159900A0 (en) 2004-06-20

Family

ID=27494353

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15990002A IL159900A0 (en) 2001-08-07 2002-08-05 Cysteine mutants and methods for detecting ligand binding to biological molecules

Country Status (7)

Country Link
EP (1) EP1421379A2 (en)
JP (1) JP2005503380A (en)
CA (1) CA2454246A1 (en)
IL (1) IL159900A0 (en)
MX (1) MXPA04001000A (en)
NZ (1) NZ530721A (en)
WO (1) WO2003014308A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7214487B2 (en) 1998-06-26 2007-05-08 Sunesis Pharmaceuticals, Inc. Methods for identifying compounds that modulate enzymatic activities by employing covalently bonded target-extender complexes with ligand candidates
WO2003081210A2 (en) 2002-03-21 2003-10-02 Sunesis Pharmaceuticals, Inc. Identification of kinase inhibitors
AU2003270848A1 (en) * 2003-09-17 2005-04-27 Sunesis Pharmaceuticals, Inc. Identification of kinase inhibitors
WO2025148785A1 (en) * 2024-01-08 2025-07-17 Fbd Biologics Limited Engineered il-2 variants and methods of use thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE199109T1 (en) * 1992-03-27 2001-02-15 Akiko Itai METHOD FOR ANALYZING THE STRUCTURE OF STABLE COMPOSITE BIOPOLYMER LIGAND MOLECULES
US6010861A (en) * 1994-08-03 2000-01-04 Dgi Biotechnologies, Llc Target specific screens and their use for discovering small organic molecular pharmacophores

Also Published As

Publication number Publication date
JP2005503380A (en) 2005-02-03
WO2003014308A9 (en) 2004-04-22
CA2454246A1 (en) 2003-02-20
EP1421379A2 (en) 2004-05-26
NZ530721A (en) 2006-09-29
WO2003014308A3 (en) 2004-03-18
MXPA04001000A (en) 2004-06-25
WO2003014308A2 (en) 2003-02-20

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