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IL136718A0 - Method and reagents for the quantification of solid-phase reactions using fluorine nmr - Google Patents

Method and reagents for the quantification of solid-phase reactions using fluorine nmr

Info

Publication number
IL136718A0
IL136718A0 IL13671898A IL13671898A IL136718A0 IL 136718 A0 IL136718 A0 IL 136718A0 IL 13671898 A IL13671898 A IL 13671898A IL 13671898 A IL13671898 A IL 13671898A IL 136718 A0 IL136718 A0 IL 136718A0
Authority
IL
Israel
Prior art keywords
solid
quantification
reagents
phase reactions
fluorine nmr
Prior art date
Application number
IL13671898A
Other languages
English (en)
Original Assignee
Aventis Pharm Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US1997/023920 external-priority patent/WO1998029376A1/fr
Application filed by Aventis Pharm Prod Inc filed Critical Aventis Pharm Prod Inc
Publication of IL136718A0 publication Critical patent/IL136718A0/xx

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N24/00—Investigating or analyzing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/12—Hydrolysis
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/14—Esterification
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/18—Introducing halogen atoms or halogen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/18—Introducing halogen atoms or halogen-containing groups
    • C08F8/20—Halogenation
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/26—Removing halogen atoms or halogen-containing groups from the molecule
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/34—Introducing sulfur atoms or sulfur-containing groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2800/00—Copolymer characterised by the proportions of the comonomers expressed
    • C08F2800/20—Copolymer characterised by the proportions of the comonomers expressed as weight or mass percentages
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2810/00—Chemical modification of a polymer
    • C08F2810/20—Chemical modification of a polymer leading to a crosslinking, either explicitly or inherently
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N24/00—Investigating or analyzing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects
    • G01N24/08—Investigating or analyzing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects by using nuclear magnetic resonance

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Steroid Compounds (AREA)
  • Catalysts (AREA)
  • Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
IL13671898A 1997-12-17 1998-12-14 Method and reagents for the quantification of solid-phase reactions using fluorine nmr IL136718A0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PCT/US1997/023920 WO1998029376A1 (fr) 1996-12-19 1997-12-17 Procedes pour la synthese en phase solide de composes a base d'aldehydes, de cetones, d'oximes, d'amines et de composes d'acide hydroxamique
US9056398P 1998-06-24 1998-06-24
US9055898P 1998-06-24 1998-06-24
PCT/US1998/026512 WO1999031491A1 (fr) 1997-12-17 1998-12-14 Procede et reactifs pour l'evaluation de reactions en phase solide utilisant la rnm au fluor

Publications (1)

Publication Number Publication Date
IL136718A0 true IL136718A0 (en) 2001-06-14

Family

ID=27376603

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13671898A IL136718A0 (en) 1997-12-17 1998-12-14 Method and reagents for the quantification of solid-phase reactions using fluorine nmr

Country Status (16)

Country Link
EP (1) EP1044364B8 (fr)
JP (1) JP2003522934A (fr)
CN (1) CN1205468C (fr)
AT (1) ATE364837T1 (fr)
AU (1) AU748529C (fr)
BG (1) BG65184B1 (fr)
BR (1) BR9813701A (fr)
CA (1) CA2315152A1 (fr)
DE (1) DE69837936T2 (fr)
DK (1) DK1044364T3 (fr)
ES (1) ES2288310T3 (fr)
HU (1) HUP0200726A2 (fr)
IL (1) IL136718A0 (fr)
MX (1) MXPA00006050A (fr)
PL (1) PL197620B1 (fr)
WO (1) WO1999031491A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8173441B2 (en) * 2000-09-27 2012-05-08 Universiteit Leiden Method for applying NMR for ligand discovery or as a drug screening tool
FR2955862B1 (fr) * 2010-02-02 2012-07-13 Commissariat Energie Atomique Materiau polymere fluorocarbone et procede de synthese
CN103487455B (zh) * 2013-09-24 2016-04-27 上海大学 一种快速定量检测橄榄油中含羟基化合物的方法
CN108593696B (zh) * 2018-04-26 2020-11-03 南京明捷生物医药检测有限公司 一种利用定量核磁测定多肽中三氟乙酸残留的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5565324A (en) * 1992-10-01 1996-10-15 The Trustees Of Columbia University In The City Of New York Complex combinatorial chemical libraries encoded with tags
US5566324A (en) * 1992-12-24 1996-10-15 Ncr Corporation Computer apparatus including a main memory prefetch cache and method of operation thereof
GB9515070D0 (en) * 1995-07-22 1995-09-20 Zeneca Ltd Label
US6355490B1 (en) * 1996-09-13 2002-03-12 Jill Edie Hochlowski Attached tags for use in combinatorial chemistry synthesis

Also Published As

Publication number Publication date
AU748529B2 (en) 2002-06-06
DE69837936T2 (de) 2008-02-28
BG104614A (en) 2001-10-31
ATE364837T1 (de) 2007-07-15
CN1205468C (zh) 2005-06-08
BG65184B1 (bg) 2007-05-31
ES2288310T3 (es) 2008-01-01
EP1044364B1 (fr) 2007-06-13
AU2556999A (en) 1999-07-05
EP1044364B8 (fr) 2008-01-02
HUP0200726A2 (en) 2002-06-29
DE69837936D1 (de) 2007-07-26
CA2315152A1 (fr) 1999-06-24
MXPA00006050A (es) 2004-05-21
BR9813701A (pt) 2000-12-12
JP2003522934A (ja) 2003-07-29
DK1044364T3 (da) 2007-09-24
EP1044364A1 (fr) 2000-10-18
AU748529C (en) 2002-10-17
WO1999031491A1 (fr) 1999-06-24
PL341357A1 (en) 2001-04-09
PL197620B1 (pl) 2008-04-30
EP1044364A4 (fr) 2004-10-06
CN1284165A (zh) 2001-02-14

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