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IL136459A0 - Antibody library - Google Patents

Antibody library

Info

Publication number
IL136459A0
IL136459A0 IL13645900A IL13645900A IL136459A0 IL 136459 A0 IL136459 A0 IL 136459A0 IL 13645900 A IL13645900 A IL 13645900A IL 13645900 A IL13645900 A IL 13645900A IL 136459 A0 IL136459 A0 IL 136459A0
Authority
IL
Israel
Prior art keywords
antibody library
library
antibody
Prior art date
Application number
IL13645900A
Other languages
English (en)
Original Assignee
Galim Galil Immunology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galim Galil Immunology Ltd filed Critical Galim Galil Immunology Ltd
Priority to IL13645900A priority Critical patent/IL136459A0/xx
Priority to PCT/IL2001/000496 priority patent/WO2001092291A2/fr
Priority to AU62636/01A priority patent/AU6263601A/en
Publication of IL136459A0 publication Critical patent/IL136459A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/02Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1037Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
IL13645900A 2000-05-30 2000-05-30 Antibody library IL136459A0 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
IL13645900A IL136459A0 (en) 2000-05-30 2000-05-30 Antibody library
PCT/IL2001/000496 WO2001092291A2 (fr) 2000-05-30 2001-05-30 Repertoires d'anticorps et de recepteurs des lymphocytes t
AU62636/01A AU6263601A (en) 2000-05-30 2001-05-30 Antibody and t-cell receptor libraries

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL13645900A IL136459A0 (en) 2000-05-30 2000-05-30 Antibody library

Publications (1)

Publication Number Publication Date
IL136459A0 true IL136459A0 (en) 2001-06-14

Family

ID=11074201

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13645900A IL136459A0 (en) 2000-05-30 2000-05-30 Antibody library

Country Status (3)

Country Link
AU (1) AU6263601A (fr)
IL (1) IL136459A0 (fr)
WO (1) WO2001092291A2 (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003054021A2 (fr) * 2001-12-20 2003-07-03 Agricultural Research Council Bibliotheque combinatoire de fragments d'anticorps semi-synthetiques
ES2327229T3 (es) 2002-11-09 2009-10-27 Immunocore Ltd. Presentacion del receptor de linfocitos t.
TWI333977B (en) 2003-09-18 2010-12-01 Symphogen As Method for linking sequences of interest
GB0411771D0 (en) * 2004-05-26 2004-06-30 Avidex Ltd Nucleoproteins displaying native T cell receptor libraries
US7994298B2 (en) 2004-09-24 2011-08-09 Trustees Of Dartmouth College Chimeric NK receptor and methods for treating cancer
CA2583306A1 (fr) * 2004-10-08 2006-08-10 Intronn, Inc. Utilisation d'un trans-epissage d'arn pour le transfert genique d'anticorps et la production polypeptidique d'anticorps
JP5017118B2 (ja) * 2004-10-08 2012-09-05 バークシス コーポレーション 組換えタンパク質をインビボ生産するための、非常に豊富な転写産物の標的化トランススプライシング
BRPI0712073B8 (pt) 2006-05-17 2021-05-25 Hoffmann La Roche ácido nucléico para produção de um polipeptídio ou proteína heteróloga
RU2459868C2 (ru) 2007-03-01 2012-08-27 Симфоген А/С Способ клонирования когнатных антител
ES2511051T3 (es) 2009-05-29 2014-10-22 Morphosys Ag Colección de anticuerpos sintéticos para tratar enfermedades
US9273283B2 (en) 2009-10-29 2016-03-01 The Trustees Of Dartmouth College Method of producing T cell receptor-deficient T cells expressing a chimeric receptor
US12492376B2 (en) 2009-10-29 2025-12-09 The Trustees Of Dartmouth College T-cell receptor-deficient T cell compositions
WO2011059836A2 (fr) 2009-10-29 2011-05-19 Trustees Of Dartmouth College Compositions de lymphocytes t déficientes en récepteurs de lymphocytes t
WO2011092313A1 (fr) 2010-01-29 2011-08-04 Morphosys Ag Banques combinatoires d'anticorps de rongeurs
WO2012066129A1 (fr) 2010-11-19 2012-05-24 Morphosys Ag Collection et méthodes pour l'utiliser
US9833476B2 (en) 2011-08-31 2017-12-05 The Trustees Of Dartmouth College NKP30 receptor targeted therapeutics
JP6389166B2 (ja) 2012-05-07 2018-09-12 トラスティーズ・オブ・ダートマス・カレッジ 抗b7−h6抗体、融合タンパク質、及びこれらを使用する方法
CN106574270B (zh) * 2014-07-03 2021-07-13 豪夫迈·罗氏有限公司 多肽表达系统
EP3303591B1 (fr) * 2015-06-01 2019-04-03 Medigene Immunotherapies GmbH Bibliothèque de récepteurs de cellules t
AU2016273214B2 (en) 2015-06-01 2018-10-18 Medigene Immunotherapies Gmbh Method for generating antibodies against T cell receptor
EP3901254A1 (fr) 2015-12-23 2021-10-27 Medigene Immunotherapies GmbH Nouvelle génération de récepteurs de lymphocytes t spécifiques d'antigène
EP3472198B1 (fr) 2016-09-29 2020-03-04 H. Hoffnabb-La Roche Ag Procede ameliore de selection de polypeptide de production de cellules

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6673986B1 (en) * 1990-01-12 2004-01-06 Abgenix, Inc. Generation of xenogeneic antibodies
US5874299A (en) * 1990-08-29 1999-02-23 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies

Also Published As

Publication number Publication date
WO2001092291A2 (fr) 2001-12-06
WO2001092291A3 (fr) 2002-05-16
AU6263601A (en) 2001-12-11

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