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IL117686A - Synthetic peptides and pharmaceutical compositions comprising them for the treatment of systemic lupus erythematosus - Google Patents

Synthetic peptides and pharmaceutical compositions comprising them for the treatment of systemic lupus erythematosus

Info

Publication number
IL117686A
IL117686A IL11768696A IL11768696A IL117686A IL 117686 A IL117686 A IL 117686A IL 11768696 A IL11768696 A IL 11768696A IL 11768696 A IL11768696 A IL 11768696A IL 117686 A IL117686 A IL 117686A
Authority
IL
Israel
Prior art keywords
treatment
pharmaceutical compositions
lupus erythematosus
systemic lupus
synthetic peptides
Prior art date
Application number
IL11768696A
Other languages
English (en)
Other versions
IL117686A0 (en
Inventor
Edna Mozes
Ari Waisman
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Publication of IL117686A0 publication Critical patent/IL117686A0/xx
Publication of IL117686A publication Critical patent/IL117686A/xx

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/643Albumins, e.g. HSA, BSA, ovalbumin or a Keyhole Limpet Hemocyanin [KHL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/74Inducing cell proliferation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/10Musculoskeletal or connective tissue disorders
    • G01N2800/101Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis
    • G01N2800/104Lupus erythematosus [SLE]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/24Immunology or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Rehabilitation Therapy (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IL11768696A 1995-03-28 1996-03-27 Synthetic peptides and pharmaceutical compositions comprising them for the treatment of systemic lupus erythematosus IL117686A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL11315995A IL113159A0 (en) 1995-03-28 1995-03-28 Synthetic peptides and pharmaceutical compositions comprising them

Publications (2)

Publication Number Publication Date
IL117686A0 IL117686A0 (en) 1996-07-23
IL117686A true IL117686A (en) 2000-10-31

Family

ID=11067281

Family Applications (2)

Application Number Title Priority Date Filing Date
IL11315995A IL113159A0 (en) 1995-03-28 1995-03-28 Synthetic peptides and pharmaceutical compositions comprising them
IL11768696A IL117686A (en) 1995-03-28 1996-03-27 Synthetic peptides and pharmaceutical compositions comprising them for the treatment of systemic lupus erythematosus

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL11315995A IL113159A0 (en) 1995-03-28 1995-03-28 Synthetic peptides and pharmaceutical compositions comprising them

Country Status (11)

Country Link
EP (1) EP0817650B1 (xx)
JP (1) JP3862752B2 (xx)
AT (1) ATE253944T1 (xx)
AU (1) AU706772B2 (xx)
CA (1) CA2217776C (xx)
DE (1) DE69630682T2 (xx)
DK (1) DK0817650T3 (xx)
ES (1) ES2212801T3 (xx)
IL (2) IL113159A0 (xx)
PT (1) PT817650E (xx)
WO (1) WO1996030057A1 (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6613536B1 (en) * 1995-03-28 2003-09-02 Yeda Research And Development Co. Ltd. Synthetic peptides and pharmaceutical compositions comprising them for the treatment of systemic lupus erythematosus
US6660843B1 (en) 1998-10-23 2003-12-09 Amgen Inc. Modified peptides as therapeutic agents
US7488590B2 (en) 1998-10-23 2009-02-10 Amgen Inc. Modified peptides as therapeutic agents
DK1783222T3 (da) 1998-10-23 2012-07-09 Kirin Amgen Inc Dimere trombopoietiske peptidomimetika, der binder til MPL-receptor og har trombopoietisk aktivitet
IL141647A0 (en) * 2001-02-26 2002-03-10 Yeda Res & Dev Synthetic human peptides and pharmaceutical compositions comprising them for the treatment of systemic lupus erythematosus
EP1511772B1 (en) * 2002-05-28 2011-11-23 Omrix Biopharmaceuticals Inc. Method for obtaining anti-idiotype antibodies
CA2513331A1 (en) * 2003-01-14 2004-08-05 Teva Pharmaceutical Industries Ltd Parenteral formulations of a peptide for the treatment of systemic lupus erythematosus
JP4817068B2 (ja) * 2003-01-14 2011-11-16 イエダ・リサーチ・アンド・ディベロップメント・カンパニー・リミテッド 全身性エリテマトーデスの治療のためのペプチドの非経口製剤
JP2008505928A (ja) 2004-07-08 2008-02-28 アムジェン インコーポレーテッド 治療用ペプチド
WO2006036834A2 (en) 2004-09-24 2006-04-06 Amgen Inc. MODIFIED Fc MOLECULES
US8008453B2 (en) 2005-08-12 2011-08-30 Amgen Inc. Modified Fc molecules
JO3324B1 (ar) 2006-04-21 2019-03-13 Amgen Inc مركبات علاجية مجففة بالتبريد تتعلق بالعصارة الهضمية

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69230612T2 (de) * 1991-05-31 2000-06-21 Connetics Corp., Palo Alto T-zell rezeptorpeptide als therapeutika für immun-verwandte krankheiten

Also Published As

Publication number Publication date
DK0817650T3 (da) 2004-03-08
IL117686A0 (en) 1996-07-23
AU5433496A (en) 1996-10-16
ES2212801T3 (es) 2004-08-01
DE69630682D1 (de) 2003-12-18
EP0817650A1 (en) 1998-01-14
EP0817650A4 (en) 1999-09-01
CA2217776A1 (en) 1996-10-03
DE69630682T2 (de) 2004-09-16
AU706772B2 (en) 1999-06-24
EP0817650B1 (en) 2003-11-12
CA2217776C (en) 2004-12-07
IL113159A0 (en) 1995-06-29
JPH11503124A (ja) 1999-03-23
ATE253944T1 (de) 2003-11-15
WO1996030057A1 (en) 1996-10-03
JP3862752B2 (ja) 2006-12-27
PT817650E (pt) 2004-03-31

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