IL116525A0 - Piperazinedione derivatives their preparation and use - Google Patents
Piperazinedione derivatives their preparation and useInfo
- Publication number
- IL116525A0 IL116525A0 IL11652595A IL11652595A IL116525A0 IL 116525 A0 IL116525 A0 IL 116525A0 IL 11652595 A IL11652595 A IL 11652595A IL 11652595 A IL11652595 A IL 11652595A IL 116525 A0 IL116525 A0 IL 116525A0
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- piperazinedione derivatives
- piperazinedione
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TW084113836A TW358094B (en) | 1994-12-23 | 1995-12-23 | Piperazinedione derivatives, their preparation and their use as moduators of multi-drug resistance |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9426224.3A GB9426224D0 (en) | 1994-12-23 | 1994-12-23 | Pharmaceutical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL116525A0 true IL116525A0 (en) | 1996-03-31 |
Family
ID=10766589
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL11652595A IL116525A0 (en) | 1994-12-23 | 1995-12-22 | Piperazinedione derivatives their preparation and use |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0799222A1 (en) |
| JP (1) | JPH10511384A (en) |
| CN (1) | CN1175253A (en) |
| AU (1) | AU698828B2 (en) |
| BG (1) | BG101602A (en) |
| BR (1) | BR9510410A (en) |
| CA (1) | CA2207500A1 (en) |
| CZ (1) | CZ190097A3 (en) |
| FI (1) | FI972660A7 (en) |
| GB (1) | GB9426224D0 (en) |
| HU (1) | HUT77943A (en) |
| IL (1) | IL116525A0 (en) |
| NO (1) | NO972937L (en) |
| NZ (1) | NZ297847A (en) |
| PL (1) | PL320916A1 (en) |
| SK (1) | SK83697A3 (en) |
| TW (1) | TW358094B (en) |
| WO (1) | WO1996020190A1 (en) |
| ZA (1) | ZA9510909B (en) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9717576D0 (en) * | 1997-08-19 | 1997-10-22 | Xenova Ltd | Pharmaceutical compounds |
| HUP0001531A3 (en) * | 1996-10-18 | 2000-09-28 | Xenova Ltd Slough | Anthranilic acid derivatives as multi drug resistance modulators |
| GB9708805D0 (en) | 1997-05-01 | 1997-06-25 | Smithkline Beecham Plc | Compounds |
| GB9810876D0 (en) | 1998-05-20 | 1998-07-22 | Smithkline Beecham Plc | Compounds |
| AU761018B2 (en) | 1998-10-08 | 2003-05-29 | Smithkline Beecham Plc | Tetrahydrobenzazepine derivatives useful as modulators of dopamine D3 receptors (antipsychotic agents) |
| BR0017067A (en) * | 2000-01-18 | 2002-10-22 | Nereus Pharmaceuticals Inc | Cell division inhibitor, dehydrogenase, method for producing a cell division and compound inhibitor |
| CA2453050A1 (en) | 2000-09-06 | 2002-03-14 | A.P. Pharma, Inc. | Degradable polyacetal polymers |
| US6693099B2 (en) | 2000-10-17 | 2004-02-17 | The Procter & Gamble Company | Substituted piperazine compounds optionally containing a quinolyl moiety for treating multidrug resistance |
| US7919497B2 (en) | 2002-08-02 | 2011-04-05 | Nereus Pharmaceuticals, Inc. | Analogs of dehydrophenylahistins and their therapeutic use |
| US7935704B2 (en) | 2003-08-01 | 2011-05-03 | Nereus Pharmaceuticals, Inc. | Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof |
| ES2295695T3 (en) | 2002-08-02 | 2008-04-16 | Nereus Pharmaceuticals, Inc. | DEHYDROPHENYLHYSINAS AND ITS ANALOGS AND THE SYNTHESIS OF DEHYDROPHENYLHYTHINES AND THEIR ANALOGS. |
| US8129527B2 (en) | 2006-11-03 | 2012-03-06 | Nereus Pharmacuticals, Inc. | Analogs of dehydrophenylahistins and their therapeutic use |
| CN103396372B (en) * | 2013-08-09 | 2015-05-20 | 中国科学院南海海洋研究所 | 2,5-diketopiperazine derivative, as well as preparation method and application thereof in preparing control agent for resisting marine fouling organisms |
| JP6769982B2 (en) | 2015-03-06 | 2020-10-14 | ビヨンドスプリング ファーマシューティカルズ，インコーポレイテッド | How to treat cancer associated with RAS mutations |
| KR102623404B1 (en) | 2015-03-06 | 2024-01-11 | 비욘드스프링 파마수티컬스, 인코포레이티드. | How to Treat Brain Tumors |
| ES2910035T3 (en) | 2015-07-13 | 2022-05-11 | Beyondspring Pharmaceuticals Inc | Plinabulin Compositions |
| CA3013467A1 (en) | 2016-02-08 | 2017-08-17 | Beyondspring Pharmaceuticals, Inc. | Compositions containing tucaresol or its analogs |
| EP3463337A4 (en) | 2016-06-06 | 2020-02-12 | Beyondspring Pharmaceuticals, Inc. | COMPOSITION AND METHOD FOR REDUCING NEUTROPENIA |
| CN110431135A (en) | 2017-01-06 | 2019-11-08 | 大连万春布林医药有限公司 | Tubulin binding compounds and therapeutic uses thereof |
| KR20190109479A (en) | 2017-02-01 | 2019-09-25 | 비욘드스프링 파마수티컬스, 인코포레이티드. | How to reduce neutropenia |
| SG11202006985TA (en) | 2018-01-24 | 2020-08-28 | Beyondspring Pharmaceuticals Inc | Composition and method for reducing thrombocytopenia via the administration of plinabulin |
| WO2022216908A1 (en) | 2021-04-09 | 2022-10-13 | Beyondspring Pharmaceuticals, Inc. | Therapeutic compositions and methods for treating tumors |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2718830B2 (en) * | 1992-07-10 | 1998-02-25 | ラボラトワール、グラクソ、ソシエテ、アノニム | Anilide derivative |
| GB9217331D0 (en) * | 1992-08-14 | 1992-09-30 | Xenova Ltd | Pharmaceutical compounds |
-
1994
- 1994-12-23 GB GBGB9426224.3A patent/GB9426224D0/en active Pending
-
1995
- 1995-12-21 ZA ZA9510909A patent/ZA9510909B/en unknown
- 1995-12-22 JP JP8520301A patent/JPH10511384A/en active Pending
- 1995-12-22 IL IL11652595A patent/IL116525A0/en unknown
- 1995-12-22 HU HU9800398A patent/HUT77943A/en unknown
- 1995-12-22 FI FI972660A patent/FI972660A7/en unknown
- 1995-12-22 EP EP95941797A patent/EP0799222A1/en not_active Withdrawn
- 1995-12-22 CZ CZ971900A patent/CZ190097A3/en unknown
- 1995-12-22 PL PL95320916A patent/PL320916A1/en unknown
- 1995-12-22 WO PCT/GB1995/003027 patent/WO1996020190A1/en not_active Ceased
- 1995-12-22 AU AU43100/96A patent/AU698828B2/en not_active Ceased
- 1995-12-22 CA CA002207500A patent/CA2207500A1/en not_active Abandoned
- 1995-12-22 BR BR9510410-0A patent/BR9510410A/en not_active Application Discontinuation
- 1995-12-22 SK SK836-97A patent/SK83697A3/en unknown
- 1995-12-22 CN CN95197672A patent/CN1175253A/en active Pending
- 1995-12-22 NZ NZ297847A patent/NZ297847A/en unknown
- 1995-12-23 TW TW084113836A patent/TW358094B/en active
-
1997
- 1997-06-11 BG BG101602A patent/BG101602A/en unknown
- 1997-06-23 NO NO972937A patent/NO972937L/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO972937D0 (en) | 1997-06-23 |
| EP0799222A1 (en) | 1997-10-08 |
| WO1996020190A1 (en) | 1996-07-04 |
| SK83697A3 (en) | 1998-05-06 |
| CN1175253A (en) | 1998-03-04 |
| FI972660L (en) | 1997-08-22 |
| ZA9510909B (en) | 1996-08-30 |
| NO972937L (en) | 1997-06-23 |
| AU4310096A (en) | 1996-07-19 |
| BG101602A (en) | 1998-02-27 |
| CA2207500A1 (en) | 1996-07-04 |
| PL320916A1 (en) | 1997-11-10 |
| NZ297847A (en) | 1999-04-29 |
| FI972660A7 (en) | 1997-08-22 |
| FI972660A0 (en) | 1997-06-19 |
| GB9426224D0 (en) | 1995-02-22 |
| AU698828B2 (en) | 1998-11-05 |
| BR9510410A (en) | 1999-09-08 |
| HUT77943A (en) | 1998-12-28 |
| JPH10511384A (en) | 1998-11-04 |
| TW358094B (en) | 1999-05-11 |
| CZ190097A3 (en) | 1998-01-14 |
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