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IE43666L - Cephalosporin derivatives. - Google Patents

Cephalosporin derivatives.

Info

Publication number
IE43666L
IE43666L IE762192A IE219276A IE43666L IE 43666 L IE43666 L IE 43666L IE 762192 A IE762192 A IE 762192A IE 219276 A IE219276 A IE 219276A IE 43666 L IE43666 L IE 43666L
Authority
IE
Ireland
Prior art keywords
formula
cephalosporin derivatives
cephalosporin
gb1521419a
solvate
Prior art date
Application number
IE762192A
Other versions
IE43666B1 (en
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/653,999 external-priority patent/US4026888A/en
Priority claimed from US05/654,314 external-priority patent/US4061862A/en
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of IE43666L publication Critical patent/IE43666L/en
Publication of IE43666B1 publication Critical patent/IE43666B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/58—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3 with a nitrogen atom, which is a member of a hetero ring, attached in position 7

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The novel compounds of the formula I, in which the substituents have the meaning given in Claim 1, are obtained by treating a suspension of an amphoteric cephalosporin of the formula II, or a solvate thereof, with an aldehyde of the formula R<2>-CHO. The condensation products which are obtained represent novel synthetic cephalosporins which can be used as anti-bacterial agents and also as feed additives for animals. <IMAGE> [GB1521419A]
IE2192/76A 1975-10-06 1976-10-05 Cephalosporins IE43666B1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US62000575A 1975-10-06 1975-10-06
US62230675A 1975-10-10 1975-10-10
US64031775A 1975-12-12 1975-12-12
US05/653,999 US4026888A (en) 1975-10-10 1976-01-30 Certain derivatives of particular 3-thiolated cephalosporins
US05/654,314 US4061862A (en) 1975-10-06 1976-02-02 Derivatives of 7-(cyclized)phenylglycyl-3-triazolo-thio methyl cephalosporin

Publications (2)

Publication Number Publication Date
IE43666L true IE43666L (en) 1977-04-06
IE43666B1 IE43666B1 (en) 1981-04-22

Family

ID=27542000

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2192/76A IE43666B1 (en) 1975-10-06 1976-10-05 Cephalosporins

Country Status (17)

Country Link
JP (1) JPS6052718B2 (en)
AU (1) AU511344B2 (en)
BE (1) BE846890A (en)
CA (1) CA1113927A (en)
CH (1) CH629500A5 (en)
CY (1) CY1121A (en)
DE (1) DE2645144C2 (en)
DK (2) DK158673C (en)
FR (1) FR2326926A1 (en)
GB (1) GB1521419A (en)
HK (1) HK41281A (en)
IE (1) IE43666B1 (en)
KE (1) KE3154A (en)
LU (1) LU75935A1 (en)
NL (1) NL189670C (en)
SE (1) SE434952B (en)
YU (1) YU40287B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54112892A (en) * 1978-02-23 1979-09-04 Shionogi & Co Ltd Substituted imidazolidinyl-3-chloro-3-cephem-4-carboxylic acid
JPS54115354A (en) * 1978-02-27 1979-09-07 Chugai Pharmaceut Co Ltd Biphenylylglycine derivative
JP7013048B2 (en) * 2018-03-02 2022-01-31 国立大学法人大阪大学 Molecules for modifying proteins and / or peptides

Also Published As

Publication number Publication date
YU40287B (en) 1985-12-31
NL189670B (en) 1993-01-18
BE846890A (en) 1977-04-01
JPS6052718B2 (en) 1985-11-20
DK164225C (en) 1992-10-19
CY1121A (en) 1981-12-04
AU1824576A (en) 1978-04-06
DE2645144A1 (en) 1977-04-14
NL189670C (en) 1993-06-16
HK41281A (en) 1981-08-28
NL7611026A (en) 1977-04-12
DK200488A (en) 1988-04-12
SE7610989L (en) 1977-04-07
DK446576A (en) 1977-04-07
DK158673C (en) 1991-01-14
CH629500A5 (en) 1982-04-30
FR2326926A1 (en) 1977-05-06
LU75935A1 (en) 1977-05-25
FR2326926B1 (en) 1980-07-11
KE3154A (en) 1981-09-18
IE43666B1 (en) 1981-04-22
SE434952B (en) 1984-08-27
DK164225B (en) 1992-05-25
CA1113927A (en) 1981-12-08
DK158673B (en) 1990-07-02
AU511344B2 (en) 1980-08-14
YU243176A (en) 1982-06-30
JPS5246094A (en) 1977-04-12
GB1521419A (en) 1978-08-16
DK200488D0 (en) 1988-04-12
DE2645144C2 (en) 1986-11-27

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Legal Events

Date Code Title Description
MM4A Patent lapsed