IE42957L - Rosamicin (antibiotic 67-694) derivatives. - Google Patents
Rosamicin (antibiotic 67-694) derivatives.Info
- Publication number
- IE42957L IE42957L IE760375A IE37576A IE42957L IE 42957 L IE42957 L IE 42957L IE 760375 A IE760375 A IE 760375A IE 37576 A IE37576 A IE 37576A IE 42957 L IE42957 L IE 42957L
- Authority
- IE
- Ireland
- Prior art keywords
- derivatives
- compounds
- general formula
- image
- addition salts
- Prior art date
Links
- IUPCWCLVECYZRV-JZMZINANSA-N rosaramicin Chemical compound O([C@@H]1[C@@H](C)[C@H](O)CC(=O)O[C@@H]([C@H]([C@@H]2O[C@@]2(C)/C=C/C(=O)[C@H](C)C[C@@H]1CC=O)C)CC)[C@@H]1O[C@H](C)C[C@H](N(C)C)[C@H]1O IUPCWCLVECYZRV-JZMZINANSA-N 0.000 title abstract 3
- ZUHRLTIPDRLJHR-UHFFFAOYSA-N Rosamicin Natural products CCC1OC(=O)CC(O)C(C)C(OC2OC(C)CC(C2O)N(C)C)C(CC=O)CC(C)C(=O)C=CC3OC3C1C ZUHRLTIPDRLJHR-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 239000002253 acid Substances 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 2
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 239000003638 chemical reducing agent Substances 0.000 abstract 1
- 125000004185 ester group Chemical group 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 231100000614 poison Toxicity 0.000 abstract 1
- 230000007096 poisonous effect Effects 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Abstract
Derivatives of rosaramicin of the general formula <IMAGE> in which the meaning of the individual symbols is contained in Claim 1, are prepared by reducing an appropriately substituted compound of the general formula <IMAGE> or non-poisonous, pharmaceutically harmless acid addition salts of these compounds, by means of treating them with a reducing agent in the presence of acid, whereby the ester groups contained in the starting material are solvolysed, and isolating the compounds thus obtained in free form or as acid addition salts, or converting them into their esters. The novel compounds possess anti-bacterial activity.
[GB1544819A]
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55425075A | 1975-02-28 | 1975-02-28 | |
| US05/554,266 US3975372A (en) | 1975-02-28 | 1975-02-28 | Preparation of 12,13-desepoxy-12,13-dehydrorosamicin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE42957L true IE42957L (en) | 1976-08-28 |
| IE42957B1 IE42957B1 (en) | 1980-11-19 |
Family
ID=27070531
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE375/76A IE42957B1 (en) | 1975-02-28 | 1976-02-25 | Novel antibiotic substances derived from antibiotic 67-694 (rosamicin) and processes for their preparation |
Country Status (20)
| Country | Link |
|---|---|
| JP (1) | JPS51110585A (en) |
| AR (1) | AR215851A1 (en) |
| AT (1) | AT344321B (en) |
| AU (1) | AU499566B2 (en) |
| CA (1) | CA1075234A (en) |
| CH (1) | CH630391A5 (en) |
| DD (1) | DD125959A5 (en) |
| DE (1) | DE2607459A1 (en) |
| DK (1) | DK79876A (en) |
| ES (1) | ES445489A1 (en) |
| FI (1) | FI63421C (en) |
| FR (1) | FR2302102A1 (en) |
| GB (1) | GB1544819A (en) |
| HU (1) | HU176333B (en) |
| IE (1) | IE42957B1 (en) |
| IL (1) | IL49104A (en) |
| LU (1) | LU74420A1 (en) |
| NL (1) | NL7601863A (en) |
| NO (1) | NO141718C (en) |
| PT (1) | PT64836B (en) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4279896A (en) * | 1980-06-23 | 1981-07-21 | Schering Corporation | Novel 20-imino macrolide antibacterial agents |
| JPS58219197A (en) * | 1982-06-15 | 1983-12-20 | Sanraku Inc | Macrolide antibiotic derivatives |
| US4436729A (en) * | 1982-06-30 | 1984-03-13 | Schering Corporation | 23-Demycinosyltylosin compounds, pharmaceutical compositions and method of use |
| US4454314A (en) * | 1982-08-02 | 1984-06-12 | Pfizer Inc. | Antibacterial mycaminosyl tylonolide and related macrolide derivatives |
| SI8710674B (en) * | 1987-04-14 | 1998-06-30 | Pliva | Process for preparation of 10,11,12,13-tetrahydro derivatives of tylosin |
| FR2626576B1 (en) * | 1987-05-06 | 1991-07-12 | Adir | NOVEL CARBOMYCIN B DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
| PT87417B (en) * | 1987-05-06 | 1992-08-31 | Adir | PROCESS FOR THE PREPARATION OF NEW MACROLIDATE COMPOUNDS |
| US5195268A (en) * | 1991-11-21 | 1993-03-23 | Ellis Gregory T | Weedless hook for lures |
| US5218778A (en) * | 1992-05-28 | 1993-06-15 | Szantor Alfons J | Fishing lure |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR205976A1 (en) * | 1972-11-15 | 1976-06-23 | Scherico Ltd | PROCEDURE FOR THE PREPARATION OF DERIVATIVES OF 3-MONOESTERS OF ROSAMYCIN THAT HAVE ANTIBACTERIAL ACTIVITY |
-
1976
- 1976-02-18 CH CH206676A patent/CH630391A5/en not_active IP Right Cessation
- 1976-02-24 AT AT133376A patent/AT344321B/en not_active IP Right Cessation
- 1976-02-24 NO NO760606A patent/NO141718C/en unknown
- 1976-02-24 CA CA246,429A patent/CA1075234A/en not_active Expired
- 1976-02-24 FI FI760473A patent/FI63421C/en not_active IP Right Cessation
- 1976-02-24 LU LU74420A patent/LU74420A1/xx unknown
- 1976-02-24 NL NL7601863A patent/NL7601863A/en not_active Application Discontinuation
- 1976-02-24 PT PT64836A patent/PT64836B/en unknown
- 1976-02-24 DE DE19762607459 patent/DE2607459A1/en not_active Withdrawn
- 1976-02-24 GB GB7260/76A patent/GB1544819A/en not_active Expired
- 1976-02-24 ES ES445489A patent/ES445489A1/en not_active Expired
- 1976-02-24 AR AR262356A patent/AR215851A1/en active
- 1976-02-24 FR FR7605091A patent/FR2302102A1/en active Granted
- 1976-02-25 IE IE375/76A patent/IE42957B1/en unknown
- 1976-02-25 AU AU11419/76A patent/AU499566B2/en not_active Expired
- 1976-02-25 DK DK79876*#A patent/DK79876A/en not_active Application Discontinuation
- 1976-02-25 JP JP51019830A patent/JPS51110585A/ja active Pending
- 1976-02-25 IL IL49104A patent/IL49104A/en unknown
- 1976-02-26 HU HU76SCHE556A patent/HU176333B/en unknown
- 1976-02-26 DD DD191537A patent/DD125959A5/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT64836B (en) | 1977-06-07 |
| IL49104A0 (en) | 1976-04-30 |
| AR215851A1 (en) | 1979-11-15 |
| FR2302102A1 (en) | 1976-09-24 |
| FR2302102B1 (en) | 1978-12-01 |
| NL7601863A (en) | 1976-08-31 |
| AU499566B2 (en) | 1979-04-26 |
| DK79876A (en) | 1976-08-29 |
| CH630391A5 (en) | 1982-06-15 |
| FI760473A7 (en) | 1976-08-29 |
| HU176333B (en) | 1981-01-28 |
| CA1075234A (en) | 1980-04-08 |
| PT64836A (en) | 1976-03-01 |
| FI63421B (en) | 1983-02-28 |
| NO760606L (en) | 1976-08-31 |
| DE2607459A1 (en) | 1976-09-09 |
| JPS51110585A (en) | 1976-09-30 |
| LU74420A1 (en) | 1977-01-07 |
| NO141718B (en) | 1980-01-21 |
| GB1544819A (en) | 1979-04-25 |
| IL49104A (en) | 1979-12-30 |
| NO141718C (en) | 1980-04-30 |
| DD125959A5 (en) | 1977-06-08 |
| AU1141976A (en) | 1977-09-01 |
| ES445489A1 (en) | 1977-11-16 |
| FI63421C (en) | 1983-06-10 |
| IE42957B1 (en) | 1980-11-19 |
| AT344321B (en) | 1978-07-10 |
| ATA133376A (en) | 1977-11-15 |
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