IE40067B1 - 4-oxo-2-imidazolidinylideneureas - Google Patents
4-oxo-2-imidazolidinylideneureasInfo
- Publication number
- IE40067B1 IE40067B1 IE2146/74A IE214674A IE40067B1 IE 40067 B1 IE40067 B1 IE 40067B1 IE 2146/74 A IE2146/74 A IE 2146/74A IE 214674 A IE214674 A IE 214674A IE 40067 B1 IE40067 B1 IE 40067B1
- Authority
- IE
- Ireland
- Prior art keywords
- denotes
- hydrogen atom
- radical
- compounds
- aryl
- Prior art date
Links
- 150000005840 aryl radicals Chemical class 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- -1 alkyl radical Chemical class 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- TYKJILJOXAHUFO-UHFFFAOYSA-N 2-amino-1,4-dihydroimidazol-5-one Chemical class NC1=NC(=O)CN1 TYKJILJOXAHUFO-UHFFFAOYSA-N 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 238000013016 damping Methods 0.000 abstract 1
- 210000004051 gastric juice Anatomy 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/88—Nitrogen atoms, e.g. allantoin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Novel 4-oxo-2-imidazolidinylidene-ureas of the formula <IMAGE> wherein R1 denotes a hydrogen atom or a lower alkyl radical, R2 denotes a hydrogen atom or a lower alkyl radical, R3 denotes a hydrogen atom or an aryl radical, R4 denotes a hydrogen atom, an aryl radical or an arylalkyl radical and Ar denotes an aryl radical, with the exception of compounds in which R3 and R4 represent 2,6-disubstituted aryl radicals, are prepared. These compounds are obtained by reacting a correspondingly substituted 2-iminoimidazolidin-4-one with an arylisocyanate in an inert aprotic organic solvent. The novel compounds exert an inhibiting action on the secretion of gastric juices and a damping (suppressing) action on the central nervous system.
[GB1479909A]
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40802273A | 1973-10-19 | 1973-10-19 | |
| US50879574A | 1974-09-23 | 1974-09-23 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE40067L IE40067L (en) | 1975-04-19 |
| IE40067B1 true IE40067B1 (en) | 1979-02-28 |
Family
ID=27020109
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE2146/74A IE40067B1 (en) | 1973-10-19 | 1974-10-18 | 4-oxo-2-imidazolidinylideneureas |
Country Status (22)
| Country | Link |
|---|---|
| JP (1) | JPS5077367A (en) |
| AR (1) | AR210320A1 (en) |
| AT (1) | AT348536B (en) |
| BE (1) | BE821099A (en) |
| CA (1) | CA1043339A (en) |
| CH (1) | CH614198A5 (en) |
| DD (1) | DD114079A5 (en) |
| DE (1) | DE2448869A1 (en) |
| DK (1) | DK548874A (en) |
| ES (1) | ES431153A1 (en) |
| FI (1) | FI59993C (en) |
| FR (1) | FR2248042B1 (en) |
| GB (1) | GB1479909A (en) |
| HU (1) | HU170857B (en) |
| IE (1) | IE40067B1 (en) |
| IL (1) | IL45865A (en) |
| IN (1) | IN139447B (en) |
| NL (1) | NL7413718A (en) |
| NO (1) | NO141162C (en) |
| RO (1) | RO64926A (en) |
| SE (1) | SE414173B (en) |
| YU (1) | YU36932B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI800559A7 (en) * | 1979-03-14 | 1981-01-01 | F Hoffmann La Roche & Co | Urea derivatives. |
| US4265900A (en) * | 1979-10-29 | 1981-05-05 | Mcneilab, Inc. | N-Aryl-N'-imidazol-2-ylureas |
| EP2153832B1 (en) * | 2003-12-15 | 2016-03-09 | Merck Sharp & Dohme Corp. | Heterocyclic aspartyl protease inhibitors |
| CA2899938C (en) | 2013-02-12 | 2021-10-19 | Buck Institute For Research On Aging | Hydantoins that modulate bace-mediated app processing |
-
1974
- 1974-10-14 DE DE19742448869 patent/DE2448869A1/en not_active Withdrawn
- 1974-10-15 SE SE7412959A patent/SE414173B/en unknown
- 1974-10-15 BE BE149558A patent/BE821099A/en unknown
- 1974-10-16 AR AR256117A patent/AR210320A1/en active
- 1974-10-17 CH CH1395174A patent/CH614198A5/en not_active IP Right Cessation
- 1974-10-17 RO RO197480253A patent/RO64926A/en unknown
- 1974-10-17 IL IL45865A patent/IL45865A/en unknown
- 1974-10-18 NO NO743771A patent/NO141162C/en unknown
- 1974-10-18 JP JP49119494A patent/JPS5077367A/ja active Pending
- 1974-10-18 DK DK548874A patent/DK548874A/da not_active Application Discontinuation
- 1974-10-18 AT AT840974A patent/AT348536B/en not_active IP Right Cessation
- 1974-10-18 NL NL7413718A patent/NL7413718A/en not_active Application Discontinuation
- 1974-10-18 CA CA211,775A patent/CA1043339A/en not_active Expired
- 1974-10-18 FR FR7435155A patent/FR2248042B1/fr not_active Expired
- 1974-10-18 IE IE2146/74A patent/IE40067B1/en unknown
- 1974-10-18 FI FI3065/74A patent/FI59993C/en active
- 1974-10-18 ES ES431153A patent/ES431153A1/en not_active Expired
- 1974-10-18 HU HU74ME00001786A patent/HU170857B/en unknown
- 1974-10-18 YU YU2797/74A patent/YU36932B/en unknown
- 1974-10-18 GB GB45246/74A patent/GB1479909A/en not_active Expired
- 1974-10-21 DD DD181808A patent/DD114079A5/xx unknown
- 1974-11-07 IN IN2451/CAL/74A patent/IN139447B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB1479909A (en) | 1977-07-13 |
| JPS5077367A (en) | 1975-06-24 |
| YU36932B (en) | 1984-08-31 |
| SE414173B (en) | 1980-07-14 |
| DD114079A5 (en) | 1975-07-12 |
| FI306574A7 (en) | 1975-04-20 |
| AT348536B (en) | 1979-02-26 |
| IN139447B (en) | 1976-06-19 |
| AR210320A1 (en) | 1977-07-29 |
| NO141162B (en) | 1979-10-15 |
| DK548874A (en) | 1975-07-07 |
| DE2448869A1 (en) | 1975-09-04 |
| IL45865A0 (en) | 1975-02-10 |
| SE7412959L (en) | 1975-04-21 |
| FI59993C (en) | 1981-11-10 |
| NL7413718A (en) | 1975-04-22 |
| ATA840974A (en) | 1978-07-15 |
| CA1043339A (en) | 1978-11-28 |
| CH614198A5 (en) | 1979-11-15 |
| AU7443874A (en) | 1976-04-29 |
| IE40067L (en) | 1975-04-19 |
| FR2248042B1 (en) | 1978-07-21 |
| NO141162C (en) | 1980-01-23 |
| NO743771L (en) | 1975-05-20 |
| BE821099A (en) | 1975-04-15 |
| FI59993B (en) | 1981-07-31 |
| YU279774A (en) | 1982-06-18 |
| RO64926A (en) | 1980-01-15 |
| ES431153A1 (en) | 1977-02-01 |
| HU170857B (en) | 1977-09-28 |
| IL45865A (en) | 1978-01-31 |
| FR2248042A1 (en) | 1975-05-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1503244A (en) | 1,5-alkylene-3-aryl hydantoin derivatives | |
| IE39078L (en) | Substituted 1,3,5 - triazines. | |
| IE821872L (en) | Amine derivatives. | |
| IE39193L (en) | Heterocyclic substituted piperazines. | |
| IE811832L (en) | Indoles. | |
| ES449891A1 (en) | Alkyl thiourea miticides | |
| ES8301241A1 (en) | Mercaptoorganosiloxanes. | |
| IE40067B1 (en) | 4-oxo-2-imidazolidinylideneureas | |
| IE38842B1 (en) | Shaped structures of acrylonitrile polumers containing antistatic additives | |
| ES477852A1 (en) | Amides derived from carboxyl-5 pyrimidines | |
| AU538429B2 (en) | Polytriazinylamines used as stabilizers for synthetic polymers | |
| ES466590A1 (en) | Substituted oxadiazolopyrimidines | |
| ES2002663A6 (en) | Substituted diazaoxaspirodecanes, their preparation and their use as stabilizers for polymers. | |
| GB1474260A (en) | Perfluorinated amino compounds process for their manufacture and their use | |
| FR2378062A1 (en) | STABILIZATION OF THERMOPLASTIC MATERIALS USING TRIAZA-ADAMANTYL-UREES | |
| IE42390L (en) | Substituted indoles. | |
| ES8200688A1 (en) | Penicillin compounds | |
| ES451067A1 (en) | Psychotropic 2-trifluoromethyl-10-{8 3-(3-hydroxy-pyrrolidino)-propyl{9 -phenothiazine compounds | |
| IE39284L (en) | Butyramides and butyrates | |
| GB1194598A (en) | Benzofuran Derivatives | |
| IE41394B1 (en) | Substituted benimidazoles | |
| GB1340267A (en) | Herbicidal ureas | |
| GB1438420A (en) | Pyran derivatives | |
| EP0500952A4 (en) | Process for producing nitrogenous heterocycle | |
| AU7125281A (en) | Stabilized hydrocarbon soluble sodium alkyls |