HUP2500316A1 - Process for preparing (15alpha,16alpha,17beta)-estra-1,3,5(10)-triene-3,15,16,17-tetrol (estetrol) monohydrate - Google Patents

Process for preparing (15alpha,16alpha,17beta)-estra-1,3,5(10)-triene-3,15,16,17-tetrol (estetrol) monohydrate

Info

Publication number: HUP2500316A1
Authority: HU; Hungary
Prior art keywords: 15alpha; estetrol; 16alpha; 17beta; estra
Prior art date: 2023-02-02

Application number

HU2500316A

Other languages

Hungarian (hu)

Inventor

Roberto Lenna

Michele Baldrighi

Daniele Moscheni

Original Assignee

Ind Chimica Srl

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2023-02-02

Filing date

2023-02-02

Publication date

2025-11-28

2023-02-02 Application filed by Ind Chimica Srl filed Critical Ind Chimica Srl

2025-11-28 Publication of HUP2500316A1 publication Critical patent/HUP2500316A1/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
- C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

HU2500316A 2023-02-02 2023-02-02 Process for preparing (15alpha,16alpha,17beta)-estra-1,3,5(10)-triene-3,15,16,17-tetrol (estetrol) monohydrate HUP2500316A1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/EP2023/052547 WO2024160373A1 (en)	2023-02-02	2023-02-02	PROCESS FOR PREPARING (15α,16α,17β)-ESTRA-1,3,5(10)-TRIENE-3,15,16,17-TETROL (ESTETROL) MONOHYDRATE

Publications (1)

Publication Number	Publication Date
HUP2500316A1 true HUP2500316A1 (en)	2025-11-28

Family

ID=85285047

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HU2500316A HUP2500316A1 (en)	2023-02-02	2023-02-02	Process for preparing (15alpha,16alpha,17beta)-estra-1,3,5(10)-triene-3,15,16,17-tetrol (estetrol) monohydrate

Country Status (9)

Country	Link
CN (1)	CN120958008A (en)
AU (1)	AU2023428138A1 (en)
DE (1)	DE112023005720T5 (en)
ES (1)	ES3036185A2 (en)
FR (1)	FR3145563A1 (en)
GB (1)	GB2641673A (en)
HU (1)	HUP2500316A1 (en)
MX (1)	MX2025008942A (en)
WO (1)	WO2024160373A1 (en)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE469165T1 (en)	2002-11-08	2010-06-15	Pantarhei Bioscience Bv	SYNTHESIS OF OESTETROL FROM OESTRON-DERIVED STEROIDS
PT2714710T (en)	2011-06-01	2016-07-12	Estetra Sprl	Process for the production of estetrol intermediates
EP2764008B1 (en)	2011-10-07	2016-08-17	Estetra S.P.R.L.	Process for the production of estetrol
WO2013034780A2 (en)	2012-12-20	2013-03-14	Crystal Pharma, S.A.U.	Process for the preparation of estetrol and related compounds
CA2924255C (en)	2013-09-18	2022-11-22	Crystal Pharma, S.A.U.	Process for the preparation of estetrol
KR102265150B1 (en)	2013-12-12	2021-06-16	에스테트라 에스.피.알.엘.	Orally disintegrating solid dosage unit containing an estetrol component
HU231240B1 (en)	2019-09-03	2022-04-28	Richter Gedeon Nyrt.	Industrial process for the preparation of high-purity estetrol
ES2948324R1 (en)	2019-09-27	2025-09-11	Ind Chimica Srl	Process to prepare (15alpha,16alpha,17beta)-estra-1,3,5(10)-triene-3,15,16,17-tetrol monohydrate (Estetrol monohydrate)

2023
- 2023-02-02 AU AU2023428138A patent/AU2023428138A1/en active Pending
- 2023-02-02 GB GB2512709.3A patent/GB2641673A/en active Pending
- 2023-02-02 ES ES202590050A patent/ES3036185A2/en active Pending
- 2023-02-02 CN CN202380093098.7A patent/CN120958008A/en active Pending
- 2023-02-02 WO PCT/EP2023/052547 patent/WO2024160373A1/en not_active Ceased
- 2023-02-02 HU HU2500316A patent/HUP2500316A1/en unknown
- 2023-02-02 DE DE112023005720.6T patent/DE112023005720T5/en active Pending
2024
- 2024-02-01 FR FR2401020A patent/FR3145563A1/en active Pending
2025
- 2025-07-30 MX MX2025008942A patent/MX2025008942A/en unknown

Also Published As

Publication number	Publication date
CN120958008A (en)	2025-11-14
FR3145563A1 (en)	2024-08-09
WO2024160373A1 (en)	2024-08-08
GB2641673A (en)	2025-12-10
AU2023428138A1 (en)	2025-09-04
MX2025008942A (en)	2025-11-03
DE112023005720T5 (en)	2025-12-11
ES3036185A2 (en)	2025-09-15

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