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HUE033531T2 - Combination therapy of an afucosylated cd20 antibody with bendamustine - Google Patents

Combination therapy of an afucosylated cd20 antibody with bendamustine

Info

Publication number
HUE033531T2
HUE033531T2 HUE10747168A HUE10747168A HUE033531T2 HU E033531 T2 HUE033531 T2 HU E033531T2 HU E10747168 A HUE10747168 A HU E10747168A HU E10747168 A HUE10747168 A HU E10747168A HU E033531 T2 HUE033531 T2 HU E033531T2
Authority
HU
Hungary
Prior art keywords
afucosylated
bendamustine
antibody
combination therapy
therapy
Prior art date
Application number
HUE10747168A
Other languages
Hungarian (hu)
Inventor
Frank Herting
Christian Klein
Original Assignee
Roche Glycart Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41351729&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUE033531(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Roche Glycart Ag filed Critical Roche Glycart Ag
Publication of HUE033531T2 publication Critical patent/HUE033531T2/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41841,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2887Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/40Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41Glycosylation, sialylation, or fucosylation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HUE10747168A 2009-08-14 2010-08-12 Combination therapy of an afucosylated cd20 antibody with bendamustine HUE033531T2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP09010489 2009-08-14

Publications (1)

Publication Number Publication Date
HUE033531T2 true HUE033531T2 (en) 2021-12-28

Family

ID=41351729

Family Applications (2)

Application Number Title Priority Date Filing Date
HUE10747168A HUE033531T2 (en) 2009-08-14 2010-08-12 Combination therapy of an afucosylated cd20 antibody with bendamustine
HUS1700041C HUS000498I2 (en) 2009-08-14 2017-10-27 Obinutuzumab in combination with bendamustine

Family Applications After (1)

Application Number Title Priority Date Filing Date
HUS1700041C HUS000498I2 (en) 2009-08-14 2017-10-27 Obinutuzumab in combination with bendamustine

Country Status (34)

Country Link
US (4) US20110165151A1 (en)
EP (1) EP2464382B1 (en)
JP (3) JP5646626B2 (en)
KR (1) KR101425736B1 (en)
CN (2) CN102596245A (en)
AR (1) AR077866A1 (en)
AU (1) AU2010281866B2 (en)
CA (1) CA2769674C (en)
CL (1) CL2012000391A1 (en)
CR (1) CR20120036A (en)
CY (2) CY1119251T1 (en)
DK (1) DK2464382T3 (en)
ES (1) ES2630158T3 (en)
HK (1) HK1245145A1 (en)
HR (1) HRP20170972T1 (en)
HU (2) HUE033531T2 (en)
IL (1) IL217753A (en)
LT (2) LT2464382T (en)
LU (1) LUC00045I2 (en)
MA (1) MA33469B1 (en)
MX (2) MX355849B (en)
MY (1) MY163003A (en)
NO (1) NO2017054I1 (en)
NZ (1) NZ597666A (en)
PL (1) PL2464382T3 (en)
PT (1) PT2464382T (en)
RS (1) RS56146B1 (en)
SG (1) SG178324A1 (en)
SI (1) SI2464382T1 (en)
SM (1) SMT201700329T1 (en)
TW (1) TWI409079B (en)
UA (1) UA110096C2 (en)
WO (1) WO2011018224A1 (en)
ZA (1) ZA201200830B (en)

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PL2744826T3 (en) * 2011-08-16 2022-05-30 Morphosys Ag Combination therapy with an anti-cd19 antibody and a purine analog
KR20200058583A (en) * 2011-08-16 2020-05-27 모르포시스 아게 Combination therapy with an anti-cd19 antibody and a nitrogen mustard
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WO2019246312A1 (en) 2018-06-20 2019-12-26 Progenity, Inc. Treatment of a disease of the gastrointestinal tract with an immunomodulator
US12227565B2 (en) 2018-06-20 2025-02-18 Biora Therapeutics, Inc. Method of formulating a pharmaceutical composition comprising administering an immune modulator to the small intestine
CN116726361A (en) 2018-11-19 2023-09-12 比奥拉治疗股份有限公司 Methods and devices for treating diseases with biologic therapeutic agents
JP7287048B2 (en) 2019-03-27 2023-06-06 セイコーエプソン株式会社 robot
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Also Published As

Publication number Publication date
PL2464382T3 (en) 2017-09-29
MX2012001782A (en) 2012-04-19
JP5646626B2 (en) 2014-12-24
MY163003A (en) 2017-07-31
IL217753A (en) 2016-10-31
CL2012000391A1 (en) 2012-08-24
TWI409079B (en) 2013-09-21
TW201110980A (en) 2011-04-01
AR077866A1 (en) 2011-09-28
AU2010281866B2 (en) 2016-05-12
SG178324A1 (en) 2012-03-29
MX355849B (en) 2018-05-02
CY2017034I2 (en) 2018-02-14
AU2010281866A1 (en) 2012-02-02
CY1119251T1 (en) 2018-02-14
ZA201200830B (en) 2012-10-31
KR20120054068A (en) 2012-05-29
EP2464382B1 (en) 2017-05-03
HUS1700041I1 (en) 2017-11-28
WO2011018224A1 (en) 2011-02-17
NZ597666A (en) 2013-10-25
CA2769674C (en) 2018-01-23
NO2017054I1 (en) 2017-10-26
HK1245145A1 (en) 2018-08-24
SI2464382T1 (en) 2017-08-31
US20110165151A1 (en) 2011-07-07
LUC00045I1 (en) 2017-11-03
UA110096C2 (en) 2015-11-25
IL217753A0 (en) 2012-03-29
ES2630158T3 (en) 2017-08-18
HUS000498I2 (en) 2021-03-29
CN107261138A (en) 2017-10-20
JP2016222673A (en) 2016-12-28
MA33469B1 (en) 2012-07-03
KR101425736B1 (en) 2014-08-01
PT2464382T (en) 2017-06-30
HRP20170972T1 (en) 2017-09-22
BR112012002855A2 (en) 2016-11-01
JP2013501740A (en) 2013-01-17
CA2769674A1 (en) 2011-02-17
LT2464382T (en) 2017-07-25
CY2017034I1 (en) 2018-02-14
DK2464382T3 (en) 2017-07-17
RU2012109445A (en) 2013-09-27
US20160166688A9 (en) 2016-06-16
JP5963013B2 (en) 2016-08-03
JP2015071611A (en) 2015-04-16
CN102596245A (en) 2012-07-18
LUC00045I2 (en) 2018-02-26
US20140044705A1 (en) 2014-02-13
US20120315268A1 (en) 2012-12-13
LTPA2017035I1 (en) 2017-11-27
EP2464382A1 (en) 2012-06-20
SMT201700329T1 (en) 2017-09-07
RS56146B1 (en) 2017-11-30
US20150093376A1 (en) 2015-04-02
CR20120036A (en) 2012-04-18

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