HUE050834T2 - Mikroorganizmus fokozott L-lizin termelékenységgel, és eljárás L-lizin termelésére ennek alkalmazásával - Google Patents
Mikroorganizmus fokozott L-lizin termelékenységgel, és eljárás L-lizin termelésére ennek alkalmazásávalInfo
- Publication number
- HUE050834T2 HUE050834T2 HUE14817261A HUE14817261A HUE050834T2 HU E050834 T2 HUE050834 T2 HU E050834T2 HU E14817261 A HUE14817261 A HU E14817261A HU E14817261 A HUE14817261 A HU E14817261A HU E050834 T2 HUE050834 T2 HU E050834T2
- Authority
- HU
- Hungary
- Prior art keywords
- lysine
- microorganism
- enhanced
- producing
- same
- Prior art date
Links
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 title 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 244000005700 microbiome Species 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
- C12N9/1247—DNA-directed RNA polymerase (2.7.7.6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/07—Nucleotidyltransferases (2.7.7)
- C12Y207/07006—DNA-directed RNA polymerase (2.7.7.6)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020130073309A KR101594156B1 (ko) | 2013-06-25 | 2013-06-25 | Ｌ-라이신 생산능이 향상된 미생물 및 그를 이용하여 ｌ-라이신을 생산하는 방법 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE050834T2 true HUE050834T2 (hu) | 2021-01-28 |
Family
ID=52142246
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE14817261A HUE050834T2 (hu) | 2013-06-25 | 2014-06-24 | Mikroorganizmus fokozott L-lizin termelékenységgel, és eljárás L-lizin termelésére ennek alkalmazásával |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9758771B2 (hu) |
| EP (1) | EP3015546B1 (hu) |
| JP (1) | JP6195668B2 (hu) |
| KR (1) | KR101594156B1 (hu) |
| CN (2) | CN110423734B (hu) |
| BR (1) | BR112015032121B1 (hu) |
| ES (1) | ES2802949T3 (hu) |
| HU (1) | HUE050834T2 (hu) |
| PL (1) | PL3015546T3 (hu) |
| WO (1) | WO2014208981A1 (hu) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101793328B1 (ko) * | 2015-07-03 | 2017-11-03 | 씨제이제일제당 (주) | Ｌ-라이신 생산능을 갖는 미생물 및 이를 이용한 ｌ-라이신 생산 방법 |
| CN108473946B (zh) * | 2015-10-30 | 2023-01-03 | 丹尼斯科美国公司 | 增强的蛋白质表达及其方法 |
| JP7296449B2 (ja) * | 2018-08-07 | 2023-06-22 | シージェイ チェイルジェダング コーポレイション | 変異体ＲｐｏＣコード配列を含む核酸分子 |
| JP7362895B2 (ja) * | 2019-12-23 | 2023-10-17 | シージェイ チェルジェダン コーポレイション | シトクロムｃの活性が強化されたｌ－アミノ酸生産微生物およびこれを用いたｌ－アミノ酸の生産方法 |
| KR102389327B1 (ko) * | 2020-07-01 | 2022-04-20 | 씨제이제일제당 (주) | 3-메틸-2-옥소뷰타노에이트 하이드록시 메틸트랜스퍼라아제의 활성이 강화된 미생물, 및 이의 용도 |
| CN112608911B (zh) * | 2020-12-18 | 2022-07-05 | 湖州中科工业生物技术中心 | 一种rna聚合酶突变体及其应用 |
| KR102254209B1 (ko) * | 2021-01-15 | 2021-05-18 | 씨제이제일제당 (주) | 신규한 dna 중합효소 ⅲ 감마 및 타우 서브유닛 변이체 및 이를 이용한 l-라이신 생산 방법 |
| KR102344057B1 (ko) * | 2021-01-29 | 2021-12-27 | 씨제이제일제당 (주) | 신규한 단백질 변이체 및 이를 이용한 l-라이신 생산 방법 |
| KR102277034B1 (ko) * | 2021-01-29 | 2021-07-13 | 씨제이제일제당 (주) | 신규한 dahp 신타아제 변이체 및 이를 이용한 l-라이신 생산 방법 |
| KR102303747B1 (ko) * | 2021-04-12 | 2021-09-16 | 씨제이제일제당 (주) | 신규한 주요 촉진제 수퍼패밀리 퍼미에이즈 변이체 및 이를 이용한 l-라이신 생산 방법 |
| KR102314885B1 (ko) * | 2021-04-12 | 2021-10-18 | 씨제이제일제당 (주) | 신규한 단백질 변이체 및 이를 이용한 l-라이신 생산 방법 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6927046B1 (en) * | 1999-12-30 | 2005-08-09 | Archer-Daniels-Midland Company | Increased lysine production by gene amplification using coryneform bacteria |
| JP4741186B2 (ja) | 2001-12-29 | 2011-08-03 | ノボザイムス アクティーゼルスカブ | 変更された生成物生産性を有するユーバクテリアｒｎａ−ポリメラーゼ変異体 |
| US9109242B2 (en) | 2006-09-15 | 2015-08-18 | Cj Cheiljedang Corporation | Corynebacteria having enhanced L-lysine productivity and a method of producing L-lysine using the same |
| JP5048996B2 (ja) | 2006-11-10 | 2012-10-17 | 昭和電工株式会社 | 加工性に優れた耐摩耗性アルミニウム合金材およびその製造方法 |
| KR100838038B1 (ko) * | 2006-12-29 | 2008-06-12 | 씨제이제일제당 (주) | Ｌ-라이신 생산능이 향상된 코리네박테리움 속 미생물 및그를 이용한 ｌ-라이신 생산 방법 |
| KR20070057093A (ko) | 2007-01-16 | 2007-06-04 | 씨제이 주식회사 | 카나마이신 내성을 갖고 ｌ-라이신 생산능이 향상된코리네형 미생물 및 그를 이용하여 ｌ-라이신을 생산하는방법 |
| KR101012590B1 (ko) | 2008-06-25 | 2011-02-07 | 씨제이제일제당 (주) | 라이신 생산능이 향상된 코리네박테리움 및 이를 이용한 라이신 생산방법 |
| EP2501797A4 (en) | 2009-11-18 | 2013-04-17 | Myriant Corp | TECHNIQUES OF MICROBES FOR THE EFFECTIVE MANUFACTURE OF CHEMICALS |
-
2013
- 2013-06-25 KR KR1020130073309A patent/KR101594156B1/ko active Active
-
2014
- 2014-06-24 US US14/392,186 patent/US9758771B2/en active Active
- 2014-06-24 CN CN201910757268.2A patent/CN110423734B/zh active Active
- 2014-06-24 BR BR112015032121-6A patent/BR112015032121B1/pt active IP Right Grant
- 2014-06-24 CN CN201480036728.8A patent/CN105658793B/zh active Active
- 2014-06-24 WO PCT/KR2014/005576 patent/WO2014208981A1/ko not_active Ceased
- 2014-06-24 EP EP14817261.2A patent/EP3015546B1/en active Active
- 2014-06-24 ES ES14817261T patent/ES2802949T3/es active Active
- 2014-06-24 PL PL14817261T patent/PL3015546T3/pl unknown
- 2014-06-24 JP JP2016523640A patent/JP6195668B2/ja active Active
- 2014-06-24 HU HUE14817261A patent/HUE050834T2/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2016523543A (ja) | 2016-08-12 |
| JP6195668B2 (ja) | 2017-09-13 |
| CN105658793B (zh) | 2024-06-07 |
| CN105658793A (zh) | 2016-06-08 |
| KR20150000773A (ko) | 2015-01-05 |
| CN110423734A (zh) | 2019-11-08 |
| KR101594156B1 (ko) | 2016-02-15 |
| US9758771B2 (en) | 2017-09-12 |
| BR112015032121B1 (pt) | 2022-12-27 |
| CN110423734B (zh) | 2023-10-24 |
| ES2802949T3 (es) | 2021-01-22 |
| EP3015546B1 (en) | 2020-05-27 |
| EP3015546A4 (en) | 2017-01-04 |
| EP3015546A1 (en) | 2016-05-04 |
| US20160230151A1 (en) | 2016-08-11 |
| PL3015546T3 (pl) | 2020-11-16 |
| BR112015032121A2 (pt) | 2017-08-29 |
| WO2014208981A1 (ko) | 2014-12-31 |
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