[go: up one dir, main page]

HU903816D0 - Process for producing tigogenine-beta-cellobiozide - Google Patents

Process for producing tigogenine-beta-cellobiozide

Info

Publication number
HU903816D0
HU903816D0 HU903816A HU381690A HU903816D0 HU 903816 D0 HU903816 D0 HU 903816D0 HU 903816 A HU903816 A HU 903816A HU 381690 A HU381690 A HU 381690A HU 903816 D0 HU903816 D0 HU 903816D0
Authority
HU
Hungary
Prior art keywords
beta
tigogenine
cellobiozide
producing
tigogenin
Prior art date
Application number
HU903816A
Other languages
Hungarian (hu)
Other versions
HU210689B (en
HUT54708A (en
Inventor
Frank John Urban
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Priority to HU271590A priority Critical patent/HUT61571A/en
Publication of HU903816D0 publication Critical patent/HU903816D0/en
Publication of HUT54708A publication Critical patent/HUT54708A/en
Priority to HU9202715A priority patent/HU211082B/en
Publication of HU210689B publication Critical patent/HU210689B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Vascular Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Catalysts (AREA)

Abstract

Improved processes for the synthesis of tigogenin beta-cellobioside, a known hypocholesterolemic agent, using cellobiose heptaacetate and tigogenin as starting materials, and novel intermediates useful in this process.
HU903816A 1989-06-13 1990-06-12 Process for producing tigogenin-beta-cellobioside HU210689B (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
HU271590A HUT61571A (en) 1989-06-13 1990-06-12 Process for producing tigogenin-orthoester derivatives
HU9202715A HU211082B (en) 1989-06-13 1992-08-19 Process for the preparation of tigogenin ortho derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/365,588 US5010185A (en) 1989-06-13 1989-06-13 Processes for tigogenin beta-cellobioside

Publications (3)

Publication Number Publication Date
HU903816D0 true HU903816D0 (en) 1990-11-28
HUT54708A HUT54708A (en) 1991-03-28
HU210689B HU210689B (en) 1995-06-28

Family

ID=23439483

Family Applications (1)

Application Number Title Priority Date Filing Date
HU903816A HU210689B (en) 1989-06-13 1990-06-12 Process for producing tigogenin-beta-cellobioside

Country Status (23)

Country Link
US (1) US5010185A (en)
EP (1) EP0403150B1 (en)
JP (1) JPH0637514B2 (en)
KR (1) KR920002146B1 (en)
AT (1) ATE114155T1 (en)
AU (1) AU619986B2 (en)
CA (1) CA2018722A1 (en)
CZ (1) CZ279909B6 (en)
DD (1) DD295164A5 (en)
DE (1) DE69014152T2 (en)
DK (1) DK0403150T3 (en)
ES (1) ES2063269T3 (en)
FI (1) FI902937A7 (en)
HU (1) HU210689B (en)
IE (1) IE64057B1 (en)
IL (1) IL94650A (en)
NO (1) NO902600L (en)
NZ (1) NZ234028A (en)
PL (3) PL163258B1 (en)
PT (1) PT94337A (en)
RU (1) RU2042688C1 (en)
YU (1) YU47515B (en)
ZA (1) ZA904527B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5294703A (en) * 1992-05-01 1994-03-15 Eastman Kodak Company Process for preparing α-D-cellobiose octaacetate
NZ252006A (en) * 1992-06-26 1995-10-26 Pfizer Preparation of 1-o-steroidal peracyl-beta-glycosides
EP0796864A2 (en) * 1992-06-26 1997-09-24 Pfizer Inc. Steroidal glycosides for treating hypercholesterolemia
JP2578399B2 (en) * 1992-06-26 1997-02-05 ファイザー インク． Method for producing steroid-β-O-cellobioside heptaalkanoate
US5530107A (en) * 1992-10-15 1996-06-25 Pfizer Inc. Method for making steroidal peracyl glycosides
JPH08504830A (en) * 1993-04-28 1996-05-28 フアイザー・インコーポレイテツド Spirostanil glycoside crystalline monohydrate
US5502038A (en) * 1993-06-21 1996-03-26 Medical Research Foundation Of Oregon Cholesterol sequestrant glycosides that inhibit intestinal cholesterol absorption
ES2074006B1 (en) * 1993-07-05 1996-03-16 Pfizer STEROID GLYCOSIDES TO TREAT HYPERCOLESTEROLEMIA.
GB9806513D0 (en) * 1998-03-26 1998-05-27 Phytopharm Ltd Membrane-bound receptors
AU2003248057A1 (en) * 2002-07-12 2004-02-02 Shinichiro Nishimura Simple process for production of zeolite analogues functioning as acid catalysts

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4602005A (en) * 1982-05-17 1986-07-22 Medical Research Foundation Of Oregon Tigogenin cellobioside for treating hypercholesterolemia and atherosclerosis
US4602003A (en) * 1982-05-17 1986-07-22 Medical Research Foundation Of Oregon Synthetic compounds to inhibit intestinal absorption of cholesterol in the treatment of hypercholesterolemia

Also Published As

Publication number Publication date
DE69014152T2 (en) 1995-03-23
CA2018722A1 (en) 1990-12-13
HU210689B (en) 1995-06-28
IE64057B1 (en) 1995-07-12
IL94650A0 (en) 1991-04-15
JPH0331297A (en) 1991-02-12
NO902600L (en) 1990-12-14
PL289136A1 (en) 1992-02-24
US5010185A (en) 1991-04-23
NO902600D0 (en) 1990-06-12
CZ289090A3 (en) 1995-04-12
PL289135A1 (en) 1992-02-24
DE69014152D1 (en) 1994-12-22
CZ279909B6 (en) 1995-08-16
PL285593A1 (en) 1991-07-01
IL94650A (en) 1994-11-11
EP0403150A2 (en) 1990-12-19
RU2042688C1 (en) 1995-08-27
ATE114155T1 (en) 1994-12-15
KR920002146B1 (en) 1992-03-12
PL163259B1 (en) 1994-02-28
DD295164A5 (en) 1991-10-24
HUT54708A (en) 1991-03-28
FI902937A7 (en) 1990-12-14
DK0403150T3 (en) 1995-01-16
YU47515B (en) 1995-10-03
ES2063269T3 (en) 1995-01-01
ZA904527B (en) 1992-01-29
PL163258B1 (en) 1994-02-28
IE902101L (en) 1990-12-13
PT94337A (en) 1991-02-08
PL163219B1 (en) 1994-02-28
EP0403150A3 (en) 1992-06-17
AU619986B2 (en) 1992-02-06
FI902937A0 (en) 1990-06-12
YU114590A (en) 1991-10-31
KR910000779A (en) 1991-01-30
AU5707990A (en) 1991-08-01
JPH0637514B2 (en) 1994-05-18
EP0403150B1 (en) 1994-11-17
IE902101A1 (en) 1991-01-02
NZ234028A (en) 1991-10-25

Similar Documents

Publication Publication Date Title
GB2300196B (en) Polysilane, its production process and starting materials therefor
GB2233664B (en) Process for the production of synthesis gas
HU913516D0 (en) Improved process for the dividing of mixed aldehyd products
AU653934B2 (en) Catalysts for producing 1,3-diols and/or 3- hydroxyaldehydes, and processes for mixing and using same
GB2294045B (en) Novel sulfonate, process for producing the same, and bleach composition comprising the same
HU903816D0 (en) Process for producing tigogenine-beta-cellobiozide
HU9303638D0 (en) Reagent mixtures composition for blood-test, process for production of the composition, and process for examination blood-samples of glucose-content
HUT54054A (en) Process for producing etoposide composition
HU9700667D0 (en) Process for producing intermediates for the synthesis of iodinated kontrast materials
EG22746A (en) Process and intermediates for the manufacture of pyridine 2,3 dicarboxylate compounds
HUT57753A (en) Process for producing benzthiazoles usable as anthelminic and their intermediates
MX9605400A (en) Novel tetrapeptides, their manufacture and use.
YU61982A (en) Process for producing intermediates useful in the production of 1,1-dioxo-penicillanoyloxy-methyl-6-(2-amino-2-phenylacetamido0penicillanate
AU630007B2 (en) Process for producing des(64,65)-proinsulin
EP0430096A3 (en) Process for the production of 3,4-epoxybutyrate and intermediate therefor
IL92948A0 (en) Process for the production of 2,4-diamino-6-piperidinyl-pyrimidine-3-n-oxide
HU910994D0 (en) Process for the production of 2/3,4dialcoxi-benzyl/-pyrrolidines
AU5046890A (en) Process for expelling gas from waste materials
EP0402561A3 (en) Process for the manufacture of anilinofumarate via chloromaleate or chlorofumarate or mixtures thereof
WO1999032507A3 (en) Intermediates and process for the synthesis of 17-unsubstituted 16.beta.-aryloxy 4-azasteroids
ZA901047B (en) Process for the production of materials and materials produced by the process
AU5974190A (en) Novel process for the synthesis of 2-fluoro-1-olefins
DE69302950D1 (en) Process for the production of steel sheets and steel sheets, produced by this process
AU6419790A (en) Use of the reaction product of a gas and a liquid, as well as process and device for producing the same
GB9009938D0 (en) Process for the synthesis of c-c-linked biflavones,and intermediates in said synthesis

Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee