[go: up one dir, main page]

HRP950485A2 - Combination of an opioid antagonist and a selective serotonin reuptake inhibitor for treatment of alcoholism and alcohol dependence - Google Patents

Combination of an opioid antagonist and a selective serotonin reuptake inhibitor for treatment of alcoholism and alcohol dependence Download PDF

Info

Publication number
HRP950485A2
HRP950485A2 HR08/308,859A HRP950485A HRP950485A2 HR P950485 A2 HRP950485 A2 HR P950485A2 HR P950485 A HRP950485 A HR P950485A HR P950485 A2 HRP950485 A2 HR P950485A2
Authority
HR
Croatia
Prior art keywords
serotonin reuptake
selective serotonin
reuptake inhibitor
naltrexone
fluoxetine
Prior art date
Application number
HR08/308,859A
Other languages
English (en)
Croatian (hr)
Inventor
Leonard Cook
Original Assignee
Du Pont Merck Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont Merck Pharma filed Critical Du Pont Merck Pharma
Publication of HRP950485A2 publication Critical patent/HRP950485A2/hr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Addiction (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HR08/308,859A 1994-09-19 1995-09-19 Combination of an opioid antagonist and a selective serotonin reuptake inhibitor for treatment of alcoholism and alcohol dependence HRP950485A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30885994A 1994-09-19 1994-09-19

Publications (1)

Publication Number Publication Date
HRP950485A2 true HRP950485A2 (en) 1997-08-31

Family

ID=23195683

Family Applications (1)

Application Number Title Priority Date Filing Date
HR08/308,859A HRP950485A2 (en) 1994-09-19 1995-09-19 Combination of an opioid antagonist and a selective serotonin reuptake inhibitor for treatment of alcoholism and alcohol dependence

Country Status (11)

Country Link
US (1) US5958962A (fr)
EP (1) EP0782445B1 (fr)
AT (1) ATE214276T1 (fr)
AU (1) AU3419995A (fr)
CA (1) CA2197554A1 (fr)
CO (1) CO4410317A1 (fr)
DE (1) DE69525847T2 (fr)
DK (1) DK0782445T3 (fr)
HR (1) HRP950485A2 (fr)
WO (1) WO1996009047A1 (fr)
ZA (1) ZA957891B (fr)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001848A (en) * 1996-03-25 1999-12-14 The Regents Of The University Of California Bromocriptine for the treatment of alcoholics diagnosed with the D2 dopamine receptor DRD2 A1 allele
PT980241E (pt) * 1997-07-01 2004-03-31 Pfizer Prod Inc Formas de dosagem encapsuladas em gelatina de sertralina em solucao
CN1256085C (zh) 1997-07-01 2006-05-17 美国辉瑞有限公司 舍曲林盐和舍曲林的缓释剂型
WO2001032178A1 (fr) * 1999-10-29 2001-05-10 Novo Nordisk A/S Utilisation de piperidines 3,4-substituees
US6696088B2 (en) 2000-02-08 2004-02-24 Euro-Celtique, S.A. Tamper-resistant oral opioid agonist formulations
US20040253627A1 (en) * 2000-07-07 2004-12-16 Grant Zimmermann System and method for multidimensional evaluation of combinations of compositions
US7034036B2 (en) * 2000-10-30 2006-04-25 Pain Therapeutics, Inc. Inhibitors of ABC drug transporters at the blood-brain barrier
EP1262196A3 (fr) * 2001-05-23 2002-12-18 Pfizer Products Inc. Combinaison d'un inhibiteur de la recapture de monoamines et d'un antagoniste opioique pour l'utilisation dans l'alcoolisme et la dépendance alcoolique
US7034059B2 (en) 2001-07-02 2006-04-25 Sepracor Inc. Methods of using norfluoxetine
PL368612A1 (en) * 2001-08-14 2005-04-04 Biotie Therapies Corporation Method of treating alcoholism or alcohol abuse
US20140271788A1 (en) 2013-03-15 2014-09-18 Monosol Rx, Llc Sublingual and buccal film compositions
JP4545584B2 (ja) * 2002-05-17 2010-09-15 デューク ユニバーシティ 肥満を治療するための方法
US20050215552A1 (en) * 2002-05-17 2005-09-29 Gadde Kishore M Method for treating obesity
DE10237057A1 (de) * 2002-08-09 2004-03-25 Grünenthal GmbH Opioid-Rezeptor-Antagonisten in Pflasterformulierungen
MXPA05011557A (es) * 2003-04-29 2006-03-09 Orexigen Therapeutics Inc Composiciones para afectar perdida de peso.
EP1870096A3 (fr) * 2003-04-29 2011-04-20 Orexigen Therapeutics, Inc. Compositions pour influencer la perte de poids
AU2005206139B2 (en) 2004-01-13 2009-02-26 Duke University Compositions of an anticonvulsant and an antipsychotic drug for affecting weight loss
US20060160750A1 (en) * 2004-01-13 2006-07-20 Krishnan K R R Compositions of an anticonvulsant and an antipsychotic drug and methods of using the same for affecting weight loss
US7713959B2 (en) 2004-01-13 2010-05-11 Duke University Compositions of an anticonvulsant and mirtazapine to prevent weight gain
US20060100205A1 (en) * 2004-04-21 2006-05-11 Eckard Weber Compositions for affecting weight loss
EP2292220A3 (fr) 2005-11-22 2012-01-04 Orexigen Therapeutics, Inc. Compositions et procédés pour augmenter la sensibilité à l'insuline
WO2007089318A2 (fr) * 2005-11-23 2007-08-09 Orexigen Therapeutics, Inc. Compositions et méthodes de réduction de la boulimie
WO2007064586A1 (fr) * 2005-11-28 2007-06-07 Orexigen Therapeutics, Inc. Procede de traitement de desordres dus a l’anxiete
US20070212307A1 (en) * 2006-02-10 2007-09-13 Daniel Wermeling Pharmaceutical Compositions Comprising an Opioid Receptor Antagonist and Methods of Using Same
US8916195B2 (en) 2006-06-05 2014-12-23 Orexigen Therapeutics, Inc. Sustained release formulation of naltrexone
CN101588795A (zh) 2006-11-09 2009-11-25 奥雷西根治疗公司 包含中间快速溶解层的分层药物制剂
AU2007319472B2 (en) 2006-11-09 2013-01-17 Nalpropion Pharmaceuticals Llc Methods Of Administering Weight Loss Medications
US9138430B2 (en) * 2007-12-27 2015-09-22 Mylan Specialty L.P. Formulation and method for the release of paroxetine in the large intestine
US20110144145A1 (en) 2008-05-30 2011-06-16 Orexigen Therapeutics, Inc. Methods for treating visceral fat conditions
US20100168119A1 (en) * 2008-11-05 2010-07-01 Pharmorx, Inc. Compositions and methods for minimizing or reducing agonist-induced desensitization
CN102724878A (zh) 2010-01-11 2012-10-10 奥雷西根治疗公司 在重度抑郁症患者中提供体重减轻疗法的方法
KR20220042241A (ko) 2012-06-06 2022-04-04 오렉시젠 세러퓨틱스 인크. 과체중 및 비만의 치료 방법
EP2950799B1 (fr) 2013-01-30 2019-12-04 Pharmorx Therapeutics, Inc. Traitement de la dépression et autres maladies avec un agent à faible dose
US8969371B1 (en) 2013-12-06 2015-03-03 Orexigen Therapeutics, Inc. Compositions and methods for weight loss in at risk patient populations
WO2015095644A1 (fr) 2013-12-20 2015-06-25 AntiOP, Inc. Compositions de naloxone intranasales et leurs procédés de préparation et d'utilisation
EP3946547A4 (fr) 2019-03-26 2023-01-18 Pocket Naloxone Corp. Dispositifs et procédés d'administration de compositions pharmaceutiques
US11278709B1 (en) 2021-03-12 2022-03-22 Pocket Naloxone Corp. Drug delivery device and methods for using same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4777173A (en) * 1987-03-25 1988-10-11 Bristol-Myers Company Method for treatment of alcohol abuse
JPH06507416A (ja) * 1991-05-07 1994-08-25 ダイナジェン・インコーポレーテッド 禁煙のための調節された持続的放出伝達システム
US5366990A (en) * 1991-11-14 1994-11-22 Reid Larry D Method for treating alcohol abuse and alcoholism
US5512593A (en) * 1993-03-02 1996-04-30 John S. Nagle Composition and method of treating depression using natoxone or naltrexone in combination with a serotonin reuptake inhibitor

Also Published As

Publication number Publication date
CA2197554A1 (fr) 1996-03-28
ZA957891B (en) 1997-03-19
DE69525847T2 (de) 2002-09-05
DK0782445T3 (da) 2002-05-06
CO4410317A1 (es) 1997-01-09
ATE214276T1 (de) 2002-03-15
US5958962A (en) 1999-09-28
EP0782445B1 (fr) 2002-03-13
DE69525847D1 (de) 2002-04-18
EP0782445A1 (fr) 1997-07-09
AU3419995A (en) 1996-04-09
WO1996009047A1 (fr) 1996-03-28

Similar Documents

Publication Publication Date Title
HRP950485A2 (en) Combination of an opioid antagonist and a selective serotonin reuptake inhibitor for treatment of alcoholism and alcohol dependence
US6071918A (en) Combination of an opioid antagonist and a selective serotonin reuptake inhibitor for treatment of alcoholism and alcohol dependence
Mello et al. Buprenorphine suppresses cocaine self-administration by rhesus monkeys
US3966940A (en) Analgetic compositions
EP2612553B1 (fr) Compositions et procédés pour la prophylaxie et le traitement de la toxicomanie
US3773955A (en) Analgetic compositions
US4761429A (en) Enkephalinase and endorphinase inhibitors as anti-craving compositions
US3879555A (en) Method of treating drug addicts
US20250302771A1 (en) Treatment of opioid use disorder, opioid withdrawal symptoms and chronic pain
US8481599B2 (en) Compositions and methods for increasing compliance with therapies using aldehyde dehydrogenase inhibitors and treating alcoholism
AU740504B2 (en) Use of descarboethoxyloratadine for the manufacture of a medicament for the treatment of urinary incontinence, motion sickness and vertigo
KR20020081271A (ko) 물질 남용의 치료 방법
Gardell et al. Combination of naltrexone and fluoxetine on rats’ propensity to take alcoholic beverage
Homayoun et al. The effect of cyclosporin A on morphine tolerance and dependence: involvement of L-arginine/nitric oxide pathway
US20250367189A1 (en) 2-bromo-lysergic acid diethylamide for substance abuse
EP1000623A1 (fr) Utilisation de l' epinastine comme agent antitussif
AU1256501A (en) A method of treating substance addiction
Craig Analgesics and Sports Medicine
Gardell et al. Luis zyxwvutsrqponmlkjihgfedcb
De Quincey high doses of pure agonists. 2 Such complex prop
Qureshi et al. Pharmacotherapies of addiction
Highfield Effects of Ng-nitro-L-arginine, a nitric oxide synthase inhibitor, on a cellular model of morphine tolerance
Short Evidence for an Endogenous Opioid Component in Nicotine Dependence and Abstinence Syndrome
Fekkes et al. Norharman and alcohol-dependency in male wistar rats
Cannoy-Searoy The Anti-Opiate Role of Neuropeptide FF in Narcotic Tolerance and Respiration

Legal Events

Date Code Title Description
A1OB Publication of a patent application
AIPI Request for the grant of a patent on the basis of a substantive examination of a patent application
ODBI Application refused