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HRP20100290T1 - Postupak priprave rosuvastatina i intermedijera - Google Patents

Postupak priprave rosuvastatina i intermedijera Download PDF

Info

Publication number
HRP20100290T1
HRP20100290T1 HR20100290T HRP20100290T HRP20100290T1 HR P20100290 T1 HRP20100290 T1 HR P20100290T1 HR 20100290 T HR20100290 T HR 20100290T HR P20100290 T HRP20100290 T HR P20100290T HR P20100290 T1 HRP20100290 T1 HR P20100290T1
Authority
HR
Croatia
Prior art keywords
salt
compound
reacting
formula iii
image
Prior art date
Application number
HR20100290T
Other languages
English (en)
Croatian (hr)
Inventor
Fischer J�nos
Szemz� Attila
Vukics Krisztina
Erdelyi P�ter
Sz�ke Katalin
Don�t Andrea
Original Assignee
Richter Gedeon Nyrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Nyrt filed Critical Richter Gedeon Nyrt
Publication of HRP20100290T1 publication Critical patent/HRP20100290T1/hr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HR20100290T 2005-05-26 2006-05-26 Postupak priprave rosuvastatina i intermedijera HRP20100290T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU0500537A HU227120B1 (hu) 2005-05-26 2005-05-26 Eljárás rosuvastatin kalciumsójának elõállítására új intermediereken keresztül
PCT/HU2006/000049 WO2006126035A2 (fr) 2005-05-26 2006-05-26 Procede de preparation de rosuvastatine faisant intervenir des nouveaux intermediaires

Publications (1)

Publication Number Publication Date
HRP20100290T1 true HRP20100290T1 (hr) 2010-06-30

Family

ID=89986052

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20100290T HRP20100290T1 (hr) 2005-05-26 2006-05-26 Postupak priprave rosuvastatina i intermedijera

Country Status (13)

Country Link
EP (1) EP1902036B1 (fr)
AT (1) ATE461924T1 (fr)
DE (1) DE602006013136D1 (fr)
DK (1) DK1902036T3 (fr)
EA (1) EA013304B1 (fr)
ES (1) ES2342788T3 (fr)
HR (1) HRP20100290T1 (fr)
HU (1) HU227120B1 (fr)
ME (1) ME01781B (fr)
PL (1) PL1902036T3 (fr)
RS (1) RS51205B (fr)
SI (1) SI1902036T1 (fr)
WO (1) WO2006126035A2 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7994178B2 (en) 2006-09-18 2011-08-09 Teva Pharmaceutical Industries, Ltd. Crystalline rosuvastatin calcium and compositions thereof for treatment of hyperlipidaemia
WO2009157014A2 (fr) * 2008-01-30 2009-12-30 Cadila Healthcare Limited Procédé d'élaboration d'inhibiteurs de hmg-coa réductase et d'intermédiaires correspondants
WO2010029561A1 (fr) * 2008-09-09 2010-03-18 Biocon Limited Procédé de préparation d’acétonide de rosuvastatine calcique
EP2389365A1 (fr) 2009-01-15 2011-11-30 Egis Gyógyszergyár Nyilvánosan Müködö Procédés de synthèse de sels de rosuvastatine
WO2011104725A2 (fr) 2010-02-23 2011-09-01 Cadila Healthcare Limited Inhibiteurs de l'hmg-coa réductase et procédé pour leur préparation
WO2012038785A1 (fr) * 2010-09-21 2012-03-29 Biocon Limited Polymorphes d'acétonide de rosuvastatine calcique (sel calcique de l'acide (3r,5s,6e)-7-[4-(4-fluorophényl)-6-isopropyl-2-(méthanesulfonyl-méthyl- amino)pyrimidin-5-yl)vinyl)-2,2-diméthyl-l,3-dioxan-4-yle] acétique
MX2010011006A (es) 2010-10-06 2012-04-18 Senosiain S A De C V Lab Nueva sal de un derivado de pirimidina.
WO2012073256A1 (fr) * 2010-11-29 2012-06-07 Cadila Healthcare Limited Sels de rosuvastatine
CN102358747B (zh) * 2011-08-30 2012-09-19 浙江宏元药业有限公司 瑞舒伐他汀钙中间体及制备瑞舒伐他汀钙中间体和瑞舒伐他汀钙的方法
CN102796036B (zh) * 2012-09-12 2014-06-04 江苏阿尔法药业有限公司 一种阿托伐他汀钙的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9903472D0 (en) * 1999-02-17 1999-04-07 Zeneca Ltd Chemical process
GB0011163D0 (en) * 2000-05-10 2000-06-28 Astrazeneca Ab Chemical compound
GB0324791D0 (en) * 2003-10-24 2003-11-26 Astrazeneca Ab Chemical process

Also Published As

Publication number Publication date
WO2006126035A2 (fr) 2006-11-30
ME01781B (fr) 2010-12-31
RS51205B (sr) 2010-12-31
EA200702579A1 (ru) 2008-04-28
HUP0500537A2 (en) 2007-05-02
ATE461924T1 (de) 2010-04-15
DK1902036T3 (da) 2010-06-28
EA013304B1 (ru) 2010-04-30
SI1902036T1 (sl) 2010-05-31
HU227120B1 (hu) 2010-07-28
DE602006013136D1 (de) 2010-05-06
PL1902036T3 (pl) 2010-08-31
HU0500537D0 (en) 2005-08-29
ES2342788T3 (es) 2010-07-14
HUP0500537A3 (en) 2008-04-28
WO2006126035A3 (fr) 2007-06-14
EP1902036B1 (fr) 2010-03-24
EP1902036A2 (fr) 2008-03-26

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