HK20098858A1 - Inhibitors of nlrp3 - Google Patents
Inhibitors of nlrp3 Download PDFInfo
- Publication number
- HK20098858A1 HK20098858A1 HK22024085966.4A HK22024085966A HK20098858A1 HK 20098858 A1 HK20098858 A1 HK 20098858A1 HK 22024085966 A HK22024085966 A HK 22024085966A HK 20098858 A1 HK20098858 A1 HK 20098858A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- nlrp3
- inhibitors
- compounds
- methods
- disorders associated
- Prior art date
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Abstract
The present invention is directed to the compounds of Formula (A) – inhibitors of NLRP3. The inhibitors described herein can be useful in the treatment of diseases or disorders associated with NLRP3, such as Autoimmune Disease, Inflammation Disease. In particular, the invention is concerned with compounds and pharmaceutical compositions inhibiting NLRP3, methods of treating diseases or disorders associated with NLRP3, and methods of synthesizing these compounds.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63/441,687 | 2023-01-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK20098858A1 true HK20098858A1 (en) | 2024-04-05 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12168657B2 (en) | 2022-03-25 | 2024-12-17 | Ventus Therapeutics U.S., Inc. | Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 derivatives |
| US12281112B2 (en) | 2021-04-07 | 2025-04-22 | Ventus Therapeutics U.S., Inc. | Compounds for inhibiting NLRP3 and uses thereof |
| US12331048B2 (en) | 2022-10-31 | 2025-06-17 | Ventus Therapeutics U.S., Inc. | Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 inhibitors |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12281112B2 (en) | 2021-04-07 | 2025-04-22 | Ventus Therapeutics U.S., Inc. | Compounds for inhibiting NLRP3 and uses thereof |
| US12351578B2 (en) | 2021-04-07 | 2025-07-08 | Ventus Therapeutics U.S., Inc. | Compounds for inhibiting NLRP3 and uses thereof |
| US12410167B2 (en) | 2021-04-07 | 2025-09-09 | Ventus Therapeutics U.S., Inc. | Pyridazine compounds for inhibiting NLRP3 |
| US12441728B2 (en) | 2021-04-07 | 2025-10-14 | Ventus Therapeutics U.S., Inc. | Pyridazine compounds for inhibiting NLRP3 |
| US12168657B2 (en) | 2022-03-25 | 2024-12-17 | Ventus Therapeutics U.S., Inc. | Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 derivatives |
| US12331048B2 (en) | 2022-10-31 | 2025-06-17 | Ventus Therapeutics U.S., Inc. | Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 inhibitors |
| US12398136B2 (en) | 2022-10-31 | 2025-08-26 | Ventus Therapeutics U.S., Inc. | Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 inhibitors |
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