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HK16086A - A 1,4-dihydropyridine derivative its preparation and pharmaceutical compositions containing it - Google Patents

A 1,4-dihydropyridine derivative its preparation and pharmaceutical compositions containing it

Info

Publication number
HK16086A
HK16086A HK160/86A HK16086A HK16086A HK 16086 A HK16086 A HK 16086A HK 160/86 A HK160/86 A HK 160/86A HK 16086 A HK16086 A HK 16086A HK 16086 A HK16086 A HK 16086A
Authority
HK
Hong Kong
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
dihydropyridine derivative
compounds
Prior art date
Application number
HK160/86A
Inventor
Neumann Peter
Original Assignee
Sandoz Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ltd. filed Critical Sandoz Ltd.
Publication of HK16086A publication Critical patent/HK16086A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Compounds of formula I, <IMAGE> wherein X is oxygen or sulphur and R1, R2 and R3 are various substituents. The compounds are useful for treating coronary insufficiency, intermittent claudication, cerebrovascular insults, spasms in muscles and hypertension.
HK160/86A 1978-12-18 1986-03-06 A 1,4-dihydropyridine derivative its preparation and pharmaceutical compositions containing it HK16086A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1283578A CH639659A5 (en) 1978-12-18 1978-12-18 NEW 1,4-DIHYDROPYRIDINE DERIVATIVES, THEIR PRODUCTION AND USE.

Publications (1)

Publication Number Publication Date
HK16086A true HK16086A (en) 1986-03-14

Family

ID=4386824

Family Applications (1)

Application Number Title Priority Date Filing Date
HK160/86A HK16086A (en) 1978-12-18 1986-03-06 A 1,4-dihydropyridine derivative its preparation and pharmaceutical compositions containing it

Country Status (18)

Country Link
JP (1) JPS5583783A (en)
AU (1) AU536055B2 (en)
BE (1) BE880591A (en)
CH (1) CH639659A5 (en)
CY (1) CY1321A (en)
DE (1) DE2949491A1 (en)
FR (1) FR2444681A1 (en)
GB (2) GB2103203B (en)
HK (1) HK16086A (en)
IE (1) IE49496B1 (en)
IT (1) IT1164097B (en)
KE (1) KE3593A (en)
MY (1) MY8500130A (en)
NL (2) NL193066C (en)
NZ (1) NZ192422A (en)
SE (1) SE445219B (en)
SG (1) SG97585G (en)
ZA (1) ZA796842B (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3022030A1 (en) * 1980-06-12 1981-12-17 Bayer Ag, 5090 Leverkusen 4-THIAZOLE or 4-IMIDAZOLE-SUBSTITUTED, 1,4-DIHYDROPYRIDINE, METHOD FOR THE PRODUCTION THEREOF AND THE MEDICINAL PRODUCTS CONTAINING THEM
CH655658B (en) * 1980-09-18 1986-05-15
EP0080220B1 (en) * 1981-11-17 1986-02-19 FISONS plc Dihydropyridines, methods for their production and their formulation and use as pharmaceuticals
ZA83959B (en) * 1982-03-10 1984-09-26 Sandoz Ltd 1,4-dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them
US4414213A (en) * 1982-03-22 1983-11-08 Mead Johnson & Company Dihydropyridyl cyclic imidate esters and their pharmaceutical use
FR2528431B1 (en) * 1982-06-15 1986-01-10 Sandoz Sa NOVEL 1,4-DIHYDROPYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS
IL68975A (en) * 1982-06-15 1987-01-30 Sandoz Ag 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydropyridine-3,5-dicarboxylic acid ester derivatives in optically active form,their preparation and pharmaceutical compositions containing them
JPS5978186A (en) * 1982-10-27 1984-05-04 Yoshitomi Pharmaceut Ind Ltd 1,4-dihydropyridine-3,5-dicarboxylic acid ester derivative
US4794111A (en) * 1984-05-23 1988-12-27 Bayer Aktiengesellschaft Dihydropyridine preparations containing β-blockers
NL194389C (en) * 1984-06-14 2002-03-04 Novartis Ag Process for preparing a solid dispersion of a pharmaceutically active agent that has low water solubility in a solid matrix of a water-soluble polyalkylene glycol as a carrier.
US5260321A (en) * 1984-11-12 1993-11-09 Sandoz Ltd. Use of 1,4-dihydropyridine derivatives and combinations thereof with calcitonins
HU197201B (en) * 1985-10-01 1989-03-28 Sandoz Ag Process for producing oral pharmaceutical compositions of controlled solubility of the active components
DE3542794A1 (en) * 1985-12-04 1987-06-11 Bayer Ag ANTI-HYPERTENSIVE COMBINATION PREPARATION
GB8626217D0 (en) * 1986-11-03 1986-12-03 Sandoz Ltd Pharmaceutical compositions
US4816263A (en) * 1987-10-02 1989-03-28 Alza Corporation Dosage form for treating cardiovascular diseases comprising isradipine
KR940003492B1 (en) * 1988-10-27 1994-04-23 주식회사 유한양행 1,4-dihydropyridine derivative and preparation method thereof
DE4222770A1 (en) * 1992-07-10 1994-01-13 Bayer Ag Light-activated 1- (2-nitrobenzyl) -substituted 1,4-dihydropyridines
CA2477088A1 (en) 2002-02-22 2003-10-02 New River Pharmaceuticals Inc. Active agent delivery systems and methods for protecting and administering active agents
AU2003269482A1 (en) * 2003-09-10 2005-03-29 Shasun Chemicals And Drugs Limited Process for the manufacture of 2,1,3-benzoxadiazole-4-carboxaldehyde
CN103613584B (en) * 2013-11-27 2016-04-27 沈阳药科大学 The method of a kind of Isrodipine synthetic product aftertreatment

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670824C3 (en) * 1967-03-20 1978-08-03 Bayer Ag, 5090 Leverkusen 1,4-Dihydropyridine-33-dicarboxylic acid alkyl ester
FR2320750A1 (en) * 1975-08-12 1977-03-11 Hexachimie 1,4-DIHYDRO PYRIDINES AND THEIR THERAPEUTIC APPLICATION
DE2616991A1 (en) * 1976-04-17 1977-10-27 Bayer Ag Thio-substd. dihydro-pyridine derivs. - coronary vasodilators and antihypertensives prepd. e.g. by reacting dicarbonyl cpds. with amines and thio-substd. ketones
JPS5373327A (en) * 1976-12-13 1978-06-29 Matsushita Electric Ind Co Ltd Power source system
FI64938C (en) * 1977-06-20 1984-02-10 Sandoz Ag PROCEDURE FOR THE FRAMEWORK OF THERAPEUTIC THERAPEUTIC BENSOX A- AND OX BENZOTIADIAZOLYL-1,4-DIHYDROPYRID DERIVATIVES

Also Published As

Publication number Publication date
NL990014I1 (en) 1999-07-01
GB2103203B (en) 1983-06-08
NZ192422A (en) 1982-09-14
JPS5583783A (en) 1980-06-24
FR2444681A1 (en) 1980-07-18
MY8500130A (en) 1985-12-31
GB2103203A (en) 1983-02-16
SE445219B (en) 1986-06-09
BE880591A (en) 1980-06-13
ZA796842B (en) 1981-07-29
IT1164097B (en) 1987-04-08
KE3593A (en) 1986-02-07
NL193066C (en) 1998-09-08
IT7951095A0 (en) 1979-12-14
GB2037766A (en) 1980-07-16
AU536055B2 (en) 1984-04-19
CH639659A5 (en) 1983-11-30
DE2949491A1 (en) 1980-06-26
JPH0369910B2 (en) 1991-11-05
IE792445L (en) 1980-06-18
FR2444681B1 (en) 1982-10-29
IE49496B1 (en) 1985-10-16
NL7909024A (en) 1980-06-20
CY1321A (en) 1986-06-27
DE2949491C2 (en) 1988-10-27
AU5389679A (en) 1980-06-26
NL193066B (en) 1998-05-06
GB2037766B (en) 1983-02-16
SE7910188L (en) 1980-06-19
SG97585G (en) 1986-07-18

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Legal Events

Date Code Title Description
PE Patent expired