HK1218329A1 - 2型糖尿病生物标志物及其用途 - Google Patents
2型糖尿病生物标志物及其用途 Download PDFInfo
- Publication number
- HK1218329A1 HK1218329A1 HK16106276.4A HK16106276A HK1218329A1 HK 1218329 A1 HK1218329 A1 HK 1218329A1 HK 16106276 A HK16106276 A HK 16106276A HK 1218329 A1 HK1218329 A1 HK 1218329A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- glucose tolerance
- diabetes
- development
- subject
- type
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2560/00—Chemical aspects of mass spectrometric analysis of biological material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2570/00—Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/04—Endocrine or metabolic disorders
- G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Medicines Containing Plant Substances (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361758987P | 2013-01-31 | 2013-01-31 | |
| US61/758,987 | 2013-01-31 | ||
| PCT/IB2014/000426 WO2014118634A1 (en) | 2013-01-31 | 2014-01-31 | Type 2 diabetes biomarkers and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1218329A1 true HK1218329A1 (zh) | 2017-02-10 |
Family
ID=51261524
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK16106276.4A HK1218329A1 (zh) | 2013-01-31 | 2014-01-31 | 2型糖尿病生物标志物及其用途 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US10338081B2 (zh) |
| EP (1) | EP2951575A4 (zh) |
| JP (1) | JP2016510409A (zh) |
| CN (1) | CN105393117A (zh) |
| AU (1) | AU2014210871A1 (zh) |
| BR (1) | BR112015018463A2 (zh) |
| CA (1) | CA2900024A1 (zh) |
| HK (1) | HK1218329A1 (zh) |
| IL (1) | IL240285A0 (zh) |
| MX (1) | MX2015009940A (zh) |
| RU (1) | RU2015136673A (zh) |
| WO (1) | WO2014118634A1 (zh) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201415369D0 (en) * | 2014-08-29 | 2014-10-15 | Iles Raymond K | Rapid screening and evaluation of diabetes and prediabetes by glycated haemoglobin mass spectrometry |
| CA2976052C (en) | 2015-02-06 | 2023-03-21 | Metabolon, Inc. | Diagnostic methods, therapeutic agents and uses thereof |
| EP3115784A1 (en) * | 2015-07-10 | 2017-01-11 | Koss, Michael Janusz | Polypeptide marker for analysis, diagnosis and therapy of eye-related diseases |
| US10294297B2 (en) | 2016-01-29 | 2019-05-21 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for treatment using anti-NMU agents |
| WO2017194499A1 (en) * | 2016-05-09 | 2017-11-16 | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) | Tissue-specific exosomes as biomarkers |
| CN106093430A (zh) * | 2016-06-06 | 2016-11-09 | 上海阿趣生物科技有限公司 | 可用于检测糖尿病的标志物及其用途 |
| JP7097380B2 (ja) * | 2016-11-25 | 2022-07-07 | ベケッド、フレデリク | 代謝性障害 |
| RU2655635C1 (ru) * | 2017-03-16 | 2018-05-29 | Федеральное государственное автономное образовательное учреждение высшего образования "Балтийский федеральный университет имени Иммануила Канта" (БФУ им. И. Канта) | Способ ранней генетической диагностики риска развития сахарного диабета 2 типа |
| ES2788856T3 (es) | 2017-03-20 | 2020-10-23 | Forma Therapeutics Inc | Composiciones de pirrolopirrol como activadores de quinasa de piruvato (PKR) |
| WO2019097089A1 (en) | 2017-11-20 | 2019-05-23 | Zora Biosciences Oy | Methods for prediction and early detection of diabetes |
| CN110527717B (zh) * | 2018-01-31 | 2023-08-18 | 完美（广东）日用品有限公司 | 用于2型糖尿病的生物标志物及其用途 |
| CN108572256B (zh) * | 2018-04-24 | 2021-03-16 | 上海市第十人民医院 | 肝癌血清标志物cpe |
| ES2989438T3 (es) | 2018-09-19 | 2024-11-26 | Novo Nordisk Healthcare Ag | Activación de la piruvato cinasa R |
| WO2020061378A1 (en) | 2018-09-19 | 2020-03-26 | Forma Therapeutics, Inc. | Treating sickle cell disease with a pyruvate kinase r activating compound |
| US12331320B2 (en) | 2018-10-10 | 2025-06-17 | The Research Foundation For The State University Of New York | Genome edited cancer cell vaccines |
| CN111458511A (zh) * | 2019-01-21 | 2020-07-28 | 中国科学院分子细胞科学卓越创新中心 | 一种动脉粥样硬化生物标志物及其用途 |
| CN111458513A (zh) * | 2019-01-21 | 2020-07-28 | 中国科学院分子细胞科学卓越创新中心 | 一种动脉粥样硬化生物标志物及其用途 |
| CN111458512A (zh) * | 2019-01-21 | 2020-07-28 | 中国科学院分子细胞科学卓越创新中心 | 一种动脉粥样硬化生物标志物及其用途 |
| CN111781356A (zh) * | 2019-04-04 | 2020-10-16 | 清华大学 | 一种胃癌极早期细胞标志和胃癌前病变早期细胞标志及其在诊断试剂盒中的应用 |
| MA57202B1 (fr) | 2019-09-19 | 2025-09-30 | Novo Nordisk Health Care Ag | Compositions d'activation de la pyruvate kinase r (pkr) |
| RU2739118C1 (ru) * | 2019-12-23 | 2020-12-21 | федеральное государственное бюджетное образовательное учреждение высшего образования "Башкирский государственный медицинский университет" Министерства здравоохранения Российской Федерации | Способ прогнозирования течения острого периода ишемического инсульта у больных сахарным диабетом 2 типа |
| IL294337A (en) * | 2020-01-10 | 2022-08-01 | Somalogic Operating Co Inc | Methods for determining poor sugar loading |
| KR102301307B1 (ko) * | 2020-01-22 | 2021-09-13 | 계명대학교 산학협력단 | 당뇨 조기진단 또는 당뇨병 진단을 위한 바이오마커 및 이의 용도 |
| BR112022015949A2 (pt) | 2020-02-26 | 2022-10-04 | Pam Theragnostics Gmbh | Peptidilglicina alfa-amidante mono-oxigenase (pam), seu uso, formulação farmacêutica, método para determinar a atividade de pam em uma amostra de fluido corporal de um indivíduo, e kits para realizar o método para diagnóstico, prognóstico ou prevenção de risco de uma doença em um indivíduo, para a detecção do nível de pam, e para realizar o método para determinar a atividade de pam |
| JP2023515981A (ja) | 2020-02-26 | 2023-04-17 | ペーアーエム セラノスティクス ゲゼルシャフト ミット ベシュレンクテル ハフツング | ペプチジルグリシンαアミド化モノオキシゲナーゼ（ＰＡＭ）を決定する方法および診断目的でのその使用 |
| CN112461986B (zh) * | 2021-02-03 | 2021-06-08 | 首都医科大学附属北京友谊医院 | 一种用于评估空腹血糖受损和2型糖尿病患病风险的整合生物标志物体系 |
| US12128035B2 (en) | 2021-03-19 | 2024-10-29 | Novo Nordisk Health Care Ag | Activating pyruvate kinase R |
| CN113533730B (zh) * | 2021-07-23 | 2022-09-06 | 南方医科大学深圳医院 | 一种血浆外泌体标志物组合及其应用 |
| CN114354827A (zh) * | 2022-03-21 | 2022-04-15 | 天津云检医疗器械有限公司 | 代谢标志物及其在制备2型糖尿病的风险预测试剂盒中的应用和试剂盒 |
| CN120731367A (zh) | 2023-03-17 | 2025-09-30 | Pam治疗诊断有限公司 | 肽基甘氨酸α-酰胺化单加氧酶（PAM）的测定方法及其诊断用途 |
| WO2025133203A1 (en) | 2023-12-22 | 2025-06-26 | Pam Theragnostics Gmbh | Compounds and methods for a long-lasting pam |
| WO2025133225A1 (en) | 2023-12-22 | 2025-06-26 | Pam Theragnostics Gmbh | Pharmaceutical combination of peptide-gly and peptidylglycine alpha-amidating monooxygenase (pam) |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6835545B2 (en) * | 2000-05-08 | 2004-12-28 | President And Fellows Of Harvard College | Methods, products and treatments for diabetes |
| WO2007027630A2 (en) * | 2005-08-30 | 2007-03-08 | Smithkline Beecham Corporation | Genes associated with type ii diabetes mellitus |
| US20070218519A1 (en) * | 2005-10-11 | 2007-09-20 | Tethys Bioscience, Inc. | Diabetes-associated markers and methods of use thereof |
| CA2684308A1 (en) * | 2007-04-18 | 2008-10-30 | Tethys Bioscience, Inc. | Diabetes-related biomarkers and methods of use thereof |
| BRPI0815095B1 (pt) * | 2007-07-17 | 2021-04-13 | Metabolon, Inc | Método de classificação de um indivíduo de acordo com a tolerância à glicose predita em tolerância à glicose normal (ngt), tolerância à glicose de jejum prejudicada (ifg), ou tolerância à glicose prejudicada (igt), para diabetes tipo 2, método de determinação da suscetibilidade de um indivíduo a diabetes tipo 2 e método de monitoramento da progressão ou regressão do pré- diabetes em um indivíduo |
| CN102539779A (zh) * | 2010-12-27 | 2012-07-04 | 中国科学院上海生命科学研究院 | 维生素d结合蛋白作为糖尿病标志物的应用 |
-
2014
- 2014-01-31 CN CN201480019577.5A patent/CN105393117A/zh active Pending
- 2014-01-31 HK HK16106276.4A patent/HK1218329A1/zh unknown
- 2014-01-31 JP JP2015555821A patent/JP2016510409A/ja active Pending
- 2014-01-31 BR BR112015018463A patent/BR112015018463A2/pt not_active IP Right Cessation
- 2014-01-31 MX MX2015009940A patent/MX2015009940A/es unknown
- 2014-01-31 RU RU2015136673A patent/RU2015136673A/ru not_active Application Discontinuation
- 2014-01-31 WO PCT/IB2014/000426 patent/WO2014118634A1/en not_active Ceased
- 2014-01-31 AU AU2014210871A patent/AU2014210871A1/en not_active Abandoned
- 2014-01-31 CA CA2900024A patent/CA2900024A1/en not_active Abandoned
- 2014-01-31 EP EP14746108.1A patent/EP2951575A4/en not_active Withdrawn
-
2015
- 2015-07-30 US US14/813,344 patent/US10338081B2/en active Active
- 2015-08-02 IL IL240285A patent/IL240285A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20150330997A1 (en) | 2015-11-19 |
| IL240285A0 (en) | 2015-09-24 |
| AU2014210871A1 (en) | 2015-08-13 |
| EP2951575A1 (en) | 2015-12-09 |
| BR112015018463A2 (pt) | 2017-08-22 |
| CN105393117A (zh) | 2016-03-09 |
| CA2900024A1 (en) | 2014-08-07 |
| WO2014118634A1 (en) | 2014-08-07 |
| JP2016510409A (ja) | 2016-04-07 |
| EP2951575A4 (en) | 2016-11-02 |
| US10338081B2 (en) | 2019-07-02 |
| RU2015136673A (ru) | 2017-03-10 |
| MX2015009940A (es) | 2016-03-11 |
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