HK1210610A1 - Radiolabeled compounds - Google Patents

Radiolabeled compounds Download PDF

Info

Publication number: HK1210610A1
Authority: HK; Hong Kong
Prior art keywords: compound; group; subject; methyl; pde10a
Prior art date: 2013-01-31

Application number

HK15111337.2A

Other languages

English (en)

Chinese (zh)

Inventor

埃迪利奧．博羅尼

埃迪利奥．博罗尼

亞歷山大．弗洛爾

亚历山大．弗洛尔

羅卡．戈比

罗卡．戈比

托馬斯．哈通

托马斯．哈通

拉斐爾．瓦羅

拉斐尔．瓦罗

邁克爾．霍納

迈克尔．霍纳

勞倫特．馬爾塔雷洛

劳伦特．马尔塔雷洛

Original Assignee

霍夫曼-拉罗奇有限公司

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2013-01-31

Filing date

2014-01-22

Publication date

2016-04-29

2014-01-22 Application filed by 霍夫曼-拉罗奇有限公司 filed Critical 霍夫曼-拉罗奇有限公司

2016-04-29 Publication of HK1210610A1 publication Critical patent/HK1210610A1/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0453—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0463—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/002—Heterocyclic compounds
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/60—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Physics & Mathematics (AREA)
Biomedical Technology (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Optics & Photonics (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Molecular Biology (AREA)
Immunology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biochemistry (AREA)
Analytical Chemistry (AREA)
Cell Biology (AREA)
Pathology (AREA)
General Physics & Mathematics (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Food Science & Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Heart & Thoracic Surgery (AREA)
Neurology (AREA)
Cardiology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

HK15111337.2A 2013-01-31 2014-01-22 Radiolabeled compounds HK1210610A1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP13153404.2		2013-01-31
EP13153404		2013-01-31
PCT/EP2014/051180 WO2014118039A1 (fr)	2013-01-31	2014-01-22	Composés radiomarqués

Publications (1)

Publication Number	Publication Date
HK1210610A1 true HK1210610A1 (en)	2016-04-29

Family

ID=47628036

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HK15111337.2A HK1210610A1 (en)	2013-01-31	2014-01-22	Radiolabeled compounds

Country Status (11)

Country	Link
US (1)	US20160031878A1 (fr)
EP (1)	EP2951176A1 (fr)
JP (1)	JP2016513083A (fr)
KR (1)	KR20150111354A (fr)
CN (1)	CN104955825A (fr)
BR (1)	BR112015017674A2 (fr)
CA (1)	CA2899781A1 (fr)
HK (1)	HK1210610A1 (fr)
MX (1)	MX2015009377A (fr)
RU (1)	RU2015133164A (fr)
WO (1)	WO2014118039A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN112500336A (zh) *	2020-12-15	2021-03-16	内蒙古永太化学有限公司	一种度鲁特韦母核中间体的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20070032404A1 (en)	2003-07-31	2007-02-08	Bayer Pharmaceuticals Corporation	Methods for treating diabetes and related disorders using pde10a inhibitors
WO2010097367A1 (fr) *	2009-02-24	2010-09-02	Janssen Pharmaceutica Nv	Ligands radiomarqués de pde10
EP2435048B1 (fr) *	2009-05-29	2019-07-03	Merck Sharp & Dohme Corp.	Inhibiteurs de pde10 radio-marqués
ES2530884T3 (es) *	2009-09-24	2015-03-06	Hoffmann La Roche	Derivados de imidazopiridina o imidazopirimidina como inhibidores de fosfodiesterasa 10A
AU2010311493B2 (en) *	2009-10-30	2014-06-05	Janssen Pharmaceutica Nv	Radiolabelled PDE10 ligands
DE102010042833B4 (de) *	2010-10-22	2018-11-08	Helmholtz-Zentrum Dresden - Rossendorf E.V.	Neue Halogenalkoxychinazoline, deren Herstellung und Verwendung
RS54039B1 (sr) *	2010-11-10	2015-10-30	H. Lundbeck A/S	Radioobeleženi ligandi na bazi fenilimidazola
US8349824B2 (en) *	2010-12-07	2013-01-08	Hoffmann-La Roche Inc.	Triazolopyridine compounds
WO2013000924A1 (fr) *	2011-06-27	2013-01-03	Janssen Pharmaceutica Nv	Dérivés de 1-aryl-4-méthyl-[1,2,4]triazolo[4,3-a]quinoxaline

2014
- 2014-01-22 EP EP14703290.8A patent/EP2951176A1/fr not_active Withdrawn
- 2014-01-22 RU RU2015133164A patent/RU2015133164A/ru unknown
- 2014-01-22 HK HK15111337.2A patent/HK1210610A1/xx unknown
- 2014-01-22 BR BR112015017674A patent/BR112015017674A2/pt not_active IP Right Cessation
- 2014-01-22 CA CA2899781A patent/CA2899781A1/fr not_active Abandoned
- 2014-01-22 KR KR1020157020606A patent/KR20150111354A/ko not_active Withdrawn
- 2014-01-22 JP JP2015555643A patent/JP2016513083A/ja active Pending
- 2014-01-22 MX MX2015009377A patent/MX2015009377A/es unknown
- 2014-01-22 CN CN201480006218.6A patent/CN104955825A/zh active Pending
- 2014-01-22 WO PCT/EP2014/051180 patent/WO2014118039A1/fr not_active Ceased
2015
- 2015-07-30 US US14/813,293 patent/US20160031878A1/en not_active Abandoned

Also Published As

Publication number	Publication date
WO2014118039A1 (fr)	2014-08-07
JP2016513083A (ja)	2016-05-12
MX2015009377A (es)	2015-10-09
CN104955825A (zh)	2015-09-30
RU2015133164A (ru)	2017-03-06
KR20150111354A (ko)	2015-10-05
US20160031878A1 (en)	2016-02-04
CA2899781A1 (fr)	2014-08-07
EP2951176A1 (fr)	2015-12-09
BR112015017674A2 (pt)	2017-07-11

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