HK1201481A1 - Mapc therapeutics without adjunctive immunosuppressive treatment - Google Patents
Mapc therapeutics without adjunctive immunosuppressive treatment Download PDFInfo
- Publication number
- HK1201481A1 HK1201481A1 HK15102179.2A HK15102179A HK1201481A1 HK 1201481 A1 HK1201481 A1 HK 1201481A1 HK 15102179 A HK15102179 A HK 15102179A HK 1201481 A1 HK1201481 A1 HK 1201481A1
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- Prior art keywords
- cells
- mapcs
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- cell
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
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- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76095106P | 2006-01-23 | 2006-01-23 | |
| US60/760,951 | 2006-01-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1201481A1 true HK1201481A1 (en) | 2015-09-04 |
Family
ID=38123870
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK15102179.2A HK1201481A1 (en) | 2006-01-23 | 2015-03-04 | Mapc therapeutics without adjunctive immunosuppressive treatment |
| HK18109888.6A HK1250478A1 (en) | 2006-01-23 | 2018-07-31 | Mapc therapeutics without adjunctive immunosuppressive treatment |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK18109888.6A HK1250478A1 (en) | 2006-01-23 | 2018-07-31 | Mapc therapeutics without adjunctive immunosuppressive treatment |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US11992507B2 (fr) |
| EP (3) | EP2392339A1 (fr) |
| JP (11) | JP5986346B2 (fr) |
| CN (5) | CN101410125A (fr) |
| AU (1) | AU2007208368B2 (fr) |
| CA (5) | CA3124132A1 (fr) |
| DK (1) | DK1986668T3 (fr) |
| HK (2) | HK1201481A1 (fr) |
| NZ (3) | NZ727755A (fr) |
| PT (1) | PT1981515E (fr) |
| WO (1) | WO2007087293A2 (fr) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2581752Y2 (ja) | 1993-11-11 | 1998-09-24 | 株式会社三東工業社 | 二重薬液案内路を有する伸縮式掘削作業ロッド |
| US8147824B2 (en) | 1999-08-05 | 2012-04-03 | Athersys, Inc. | Immunomodulatory properties of multipotent adult progenitor cells and uses thereof |
| US7015037B1 (en) | 1999-08-05 | 2006-03-21 | Regents Of The University Of Minnesota | Multiponent adult stem cells and methods for isolation |
| ZA200200049B (en) | 2001-01-25 | 2002-07-16 | Nippon Catalytic Chem Ind | Fixed-bed shell-and-tube reactor and its usage. |
| US11000546B2 (en) | 2005-11-09 | 2021-05-11 | Athersys, Inc. | Immunomodulatory properties of MAPCs and uses thereof |
| US10117900B2 (en) | 2005-11-09 | 2018-11-06 | Athersys, Inc. | MAPC treatment of brain injuries and diseases |
| PT2471905T (pt) | 2005-12-29 | 2019-01-11 | Celularity Inc | Populações de células estaminais placentárias |
| EP2392339A1 (fr) | 2006-01-23 | 2011-12-07 | Athersys, Inc. | Traitements thérapeutiques MAPC sans traitement immunosuppresseur auxiliaire |
| CN101631852A (zh) | 2006-10-23 | 2010-01-20 | 人类起源公司 | 用胎盘细胞群治疗骨缺损的方法和组合物 |
| RS52921B (sr) | 2007-02-12 | 2014-02-28 | Anthrogenesis Corporation | Lečenje inflamatornih bolesti upotrebom placentnih matičnih ćelija |
| US20100172830A1 (en) * | 2007-03-29 | 2010-07-08 | Cellx Inc. | Extraembryonic Tissue cells and method of use thereof |
| CA2700617C (fr) | 2007-09-28 | 2018-11-06 | Celgene Cellular Therapeutics | Elimination des tumeurs au moyen d'un perfusat placentaire humain et de cellules tueuses naturelles intermediaires provenant d'un placenta humain |
| CN101978047A (zh) | 2008-01-18 | 2011-02-16 | 明尼苏达大学董事会 | 干细胞聚集体及制备和使用方法 |
| CN105766891A (zh) | 2008-08-20 | 2016-07-20 | 人类起源公司 | 改进的细胞组合物及制备所述组合物的方法 |
| CA2965883C (fr) * | 2008-08-22 | 2020-05-12 | Anthrogenesis Corporation | Methodes et compositions destinees au traitement de defauts osseux au moyen de populations de cellules placentaires |
| SG193847A1 (en) * | 2008-09-04 | 2013-10-30 | Abt Holding Co | Use of stem cells to prevent neuronal dieback |
| ES2749500T3 (es) | 2008-11-19 | 2020-03-20 | Celularity Inc | Células adherentes derivadas del amnios |
| CN104962512B (zh) * | 2009-07-21 | 2022-09-09 | Abt控股公司 | 干细胞用于减少白细胞外渗的用途 |
| AU2013231210B2 (en) * | 2009-07-21 | 2014-11-20 | Healios K.K. | Use of stem cells to reduce leukocyte extravasation |
| CA2768573C (fr) * | 2009-07-21 | 2020-09-15 | Abt Holding Company | Une methode de construction d'une banque de cellules et une methode de decouverte de medicament |
| AU2013237687B2 (en) * | 2009-07-21 | 2014-11-20 | Abt Holding Company | Use of stem cells to reduce leukocyte extravasation |
| RU2424004C1 (ru) * | 2009-11-12 | 2011-07-20 | Государственное образовательное учреждение дополнительного профессионального образования Санкт-Петербургская медицинская академия последипломного образования Федерального агентства по здравоохранению и социальному развитию | Способ лечения перинатального поражения головного мозга гипоксически-ишемического генеза у детей первого года жизни |
| US9121007B2 (en) | 2010-01-26 | 2015-09-01 | Anthrogenesis Corporatin | Treatment of bone-related cancers using placental stem cells |
| WO2011106476A1 (fr) * | 2010-02-25 | 2011-09-01 | Abt Holding Company | Modulation de l'activation des microglies |
| ES2703428T3 (es) * | 2010-02-25 | 2019-03-08 | Abt Holding Co | Modulación de la angiogénesis |
| EP2556145B1 (fr) | 2010-04-07 | 2016-07-20 | Anthrogenesis Corporation | Angiogenèse employant des cellules souches placentaires |
| MX2012011543A (es) | 2010-04-08 | 2013-05-06 | Anthrogenesis Corp | Tratamiento de sarcoidosis empleando celulas madre placentarias. |
| SG185526A1 (en) | 2010-05-12 | 2012-12-28 | Abt Holding Co | Modulation of splenocytes in cell therapy |
| WO2011143411A1 (fr) * | 2010-05-12 | 2011-11-17 | Abt Holding Company | Modulation des splénocytes en thérapie cellulaire pour une lésion cérébrale traumatique |
| JP5996533B2 (ja) | 2010-07-13 | 2016-09-21 | アントフロゲネシス コーポレーション | ナチュラルキラー細胞を生成させる方法 |
| WO2012092485A1 (fr) | 2010-12-31 | 2012-07-05 | Anthrogenesis Corporation | Amélioration de l'efficacité de cellules souches placentaires sous l'effet de molécules d'arn modulateur |
| WO2012166844A2 (fr) | 2011-06-01 | 2012-12-06 | Anthrogenesis Corporation | Traitement de la douleur à l'aide de cellules souches placentaires |
| CN115137753A (zh) | 2013-02-05 | 2022-10-04 | 细胞结构公司 | 来自胎盘的自然杀伤细胞 |
| CA2909267C (fr) | 2013-04-12 | 2022-10-25 | Saverio LA FRANCESCA | Amelioration d'organes pour une transplantation |
| US20160326494A1 (en) * | 2015-05-05 | 2016-11-10 | Katholieke Universiteit Leuven | Methods for Pancreatic Islet Transplantation |
| WO2017127123A1 (fr) | 2016-01-21 | 2017-07-27 | Abt Holding Company | Cellules souches pour la cicatrisation de plaie |
| EP3597291A4 (fr) | 2017-03-17 | 2020-01-22 | Mitsubishi Chemical Corporation | Procédé d'oxydation catalytique et procédé de fabrication d'un diène conjugué |
| US20200246390A1 (en) * | 2019-02-01 | 2020-08-06 | Abt Holding Company | Multipotent adult projenitor cells for treatment of ich |
| TWI825446B (zh) * | 2020-08-14 | 2023-12-11 | 中國醫藥大學 | 醫藥組合物治療組織缺血狀況之用途 |
| JP7762194B2 (ja) | 2021-03-16 | 2025-10-29 | 日本碍子株式会社 | ガスセンサ素子及びガスセンサ |
Family Cites Families (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4353888A (en) | 1980-12-23 | 1982-10-12 | Sefton Michael V | Encapsulation of live animal cells |
| US4749620A (en) | 1984-02-15 | 1988-06-07 | Massachusetts Institute Of Technology | Encapsulated active material system |
| US4744933A (en) | 1984-02-15 | 1988-05-17 | Massachusetts Institute Of Technology | Process for encapsulation and encapsulated active material system |
| JPH0628570B2 (ja) | 1986-02-13 | 1994-04-20 | 雪印乳業株式会社 | カプセル体の製造方法及び装置 |
| EP0301777A1 (fr) | 1987-07-28 | 1989-02-01 | Queen's University At Kingston | Microencapsulation multiple à membrane |
| US5089272A (en) | 1989-03-29 | 1992-02-18 | Snow Brand Milk Products Co., Ltd. | Process for producing capsules having a permeability-controllable membrane |
| US5084350A (en) * | 1990-02-16 | 1992-01-28 | The Royal Institution For The Advance Of Learning (Mcgill University) | Method for encapsulating biologically active material including cells |
| GB2244058B (en) | 1990-05-01 | 1993-03-24 | Courtaulds Films & Packaging | Packaging materials |
| US5578442A (en) | 1992-03-23 | 1996-11-26 | Vivorx, Inc. | Graft copolymers of polycationic species and water-soluble polymers, and use therefor |
| US6270766B1 (en) | 1992-10-08 | 2001-08-07 | The Kennedy Institute Of Rheumatology | Anti-TNF antibodies and methotrexate in the treatment of arthritis and crohn's disease |
| AU7568094A (en) | 1993-08-12 | 1995-03-14 | Cytotherapeutics, Inc. | Improved compositions and methods for the delivery of biologically active molecules using genetically altered cells contained in biocompatible immunoisolatory capsules |
| IN184685B (fr) | 1996-02-14 | 2000-09-23 | Nat Inst Immunology | |
| US5839275A (en) | 1996-08-20 | 1998-11-24 | Toyota Jidosha Kabushiki Kaisha | Fuel injection control device for a direct injection type engine |
| US7514074B2 (en) | 1997-07-14 | 2009-04-07 | Osiris Therapeutics, Inc. | Cardiac muscle regeneration using mesenchymal stem cells |
| US20030103951A1 (en) | 1997-07-14 | 2003-06-05 | Osiris Therapeutics, Inc. | Cardiac muscle regeneration using mesenchymal stem cells |
| CA2296704C (fr) | 1997-07-14 | 2010-10-19 | Osiris Therapeutics, Inc. | Regeneration du muscle cardiaque a l'aide de cellules souche mesenchymateuses |
| AU1508899A (en) | 1997-12-02 | 1999-06-16 | Chong Kun Dang Corporation | Pharmaceutical composition comprising cyclosporin solid-state microemulsion |
| ATE286118T1 (de) | 1998-03-13 | 2005-01-15 | Osiris Therapeutics Inc | Anwendungen für humane nicht autologe, mesenchymale stammzellen |
| US6368636B1 (en) | 1998-03-18 | 2002-04-09 | Osiris Therapeutics, Inc. | Mesenchymal stem cells for prevention and treatment of immune responses in transplantation |
| WO1999047163A2 (fr) | 1998-03-18 | 1999-09-23 | Osiris Therapeutics, Inc. | Cellules de souche mesenchymateuse servant a la prevention et au traitement des reponses immunitaires lors de la transplantation |
| PT1066060E (pt) | 1998-04-03 | 2003-12-31 | Osiris Therapeutics Inc | Celulas estaminais mesenquimais como imunossupressores |
| US7015037B1 (en) | 1999-08-05 | 2006-03-21 | Regents Of The University Of Minnesota | Multiponent adult stem cells and methods for isolation |
| US8147824B2 (en) | 1999-08-05 | 2012-04-03 | Athersys, Inc. | Immunomodulatory properties of multipotent adult progenitor cells and uses thereof |
| HK1049350B (en) | 1999-08-05 | 2012-01-27 | Abt Holding Company | Multipotent adult stem cells and methods for isolation |
| WO2005113748A2 (fr) * | 2004-04-21 | 2005-12-01 | Regents Of The University Of Minnesota | Generation de cellules mapc de tissu pulmonaire |
| WO2005056026A1 (fr) * | 2003-12-04 | 2005-06-23 | Regents Of The University Of Minnesota | Compositions et methodes de traitement des maladies lysosomales |
| US8075881B2 (en) * | 1999-08-05 | 2011-12-13 | Regents Of The University Of Minnesota | Use of multipotent adult stem cells in treatment of myocardial infarction and congestive heart failure |
| US6685936B2 (en) | 1999-10-12 | 2004-02-03 | Osiris Therapeutics, Inc. | Suppressor cells induced by culture with mesenchymal stem cells for treatment of immune responses in transplantation |
| US20030044843A1 (en) | 2001-01-09 | 2003-03-06 | Mitsubishi Pharma Corporation | Novel proteome analysis method and devices therefor |
| IL157332A0 (en) | 2001-02-14 | 2004-02-19 | Multipotent adult stem cells, sources thereof, methods of obtaining and maintaining same, methods of differentiation thereof, methods of use thereof and cells derived thereof | |
| US9969980B2 (en) * | 2001-09-21 | 2018-05-15 | Garnet Biotherapeutics | Cell populations which co-express CD49c and CD90 |
| JP4628618B2 (ja) | 2001-09-26 | 2011-02-09 | 富士フイルム株式会社 | 撮像光学系 |
| CA2474141A1 (fr) | 2002-01-14 | 2003-07-24 | The Board Of Trustees Of The University Of Illinois | Nouvelles cellules souches multipotentes d'origine mammalienne, methodes de preparation et methodes d'administration desdites cellules |
| KR100667746B1 (ko) | 2002-07-15 | 2007-01-11 | 삼성전자주식회사 | 드라이브 정보가 기록된 정보저장 매체 및 그 기록 방법 |
| US20040037811A1 (en) * | 2002-08-22 | 2004-02-26 | The Cleveland Clinic Foundation | Stromal cell-derived factor-1 mediates stem cell homing and tissue regeneration in ischemic cardiomyopathy |
| WO2004069172A2 (fr) | 2003-01-30 | 2004-08-19 | The Government of the United States of America as represented by the Department of Veterans Affairs | Cellules inductibles par multilignees et leurs utilisations |
| GB2417960B8 (en) | 2003-05-08 | 2008-05-09 | Cellartis Ab | A method for efficient transfer of human blastocyst-derived stem cells (hbs cells) from a feeder-supported to a feeder-free culture system |
| WO2004099395A2 (fr) * | 2003-05-08 | 2004-11-18 | Cellartis Ab | Procede de generation de cellules souches neurales |
| EP1623023B1 (fr) | 2003-05-09 | 2008-11-12 | Crucell Holland B.V. | Cultures de cellules immortalisees par e1 et procedes de culture de ces dernieres visant a en augmenter les rendements de produits |
| EP1641915B1 (fr) | 2003-06-27 | 2016-07-27 | DePuy Synthes Products, Inc. | Reparation et regeneration de tissu oculaire au moyen de cellules derivees de post-partum |
| AU2005331559B2 (en) | 2005-05-05 | 2012-04-19 | Regents Of The University Of Minnesota | Use of NK cell inhibition to facilitate persistence of engrafted MHC-I negative cells |
| AU2005331534B2 (en) | 2005-05-05 | 2011-12-08 | Regents Of The University Of Minnesota | Use of MAPC or progeny therefrom to populate lymphohematopoietic tissues |
| TW200726474A (en) * | 2005-07-15 | 2007-07-16 | Cognate Therapeutics Inc | The immunophenotype and immunogenicity of human adipose derived cells |
| WO2007047465A1 (fr) | 2005-10-13 | 2007-04-26 | Anthrogenesis Corporation | Production d'oligodendrocytes a partir de cellules souches derivees du placenta |
| US11000546B2 (en) | 2005-11-09 | 2021-05-11 | Athersys, Inc. | Immunomodulatory properties of MAPCs and uses thereof |
| US10117900B2 (en) | 2005-11-09 | 2018-11-06 | Athersys, Inc. | MAPC treatment of brain injuries and diseases |
| EP2392339A1 (fr) | 2006-01-23 | 2011-12-07 | Athersys, Inc. | Traitements thérapeutiques MAPC sans traitement immunosuppresseur auxiliaire |
| US7993918B2 (en) | 2006-08-04 | 2011-08-09 | Anthrogenesis Corporation | Tumor suppression using placental stem cells |
| RS52921B (sr) | 2007-02-12 | 2014-02-28 | Anthrogenesis Corporation | Lečenje inflamatornih bolesti upotrebom placentnih matičnih ćelija |
| WO2010082787A2 (fr) | 2009-01-15 | 2010-07-22 | 코아스템(주) | Composition pharmaceutique pour traiter des maladies osseuses ou contrer une inflammation, comprenant des cellules souches de cartilage en tant que principe actif |
| EP2241617A1 (fr) | 2009-04-06 | 2010-10-20 | Rijksuniversiteit Groningen | Cellules multipotentes dérivées du sang et procédés et utilisations associées |
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