HK1246799A1 - 替诺福韦单苄酯磷酰胺前药、其制备方法及应用 - Google Patents
替诺福韦单苄酯磷酰胺前药、其制备方法及应用 Download PDFInfo
- Publication number
- HK1246799A1 HK1246799A1 HK18106521.5A HK18106521A HK1246799A1 HK 1246799 A1 HK1246799 A1 HK 1246799A1 HK 18106521 A HK18106521 A HK 18106521A HK 1246799 A1 HK1246799 A1 HK 1246799A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- tenofovir
- monobenzyl ester
- compounds
- compound
- compound according
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510290530 | 2015-05-29 | ||
| CN201510290530 | 2015-05-29 | ||
| PCT/CN2016/083407 WO2016192560A1 (zh) | 2015-05-29 | 2016-05-26 | 替诺福韦单苄酯磷酰胺前药、其制备方法及应用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HK1246799A1 true HK1246799A1 (zh) | 2018-09-14 |
| HK1246799B HK1246799B (zh) | 2021-02-05 |
Family
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Also Published As
| Publication number | Publication date |
|---|---|
| AU2016270101B2 (en) | 2020-01-23 |
| WO2016192560A1 (zh) | 2016-12-08 |
| KR20180016437A (ko) | 2018-02-14 |
| IL255892A (en) | 2018-01-31 |
| MY191515A (en) | 2022-06-28 |
| AU2016270101A1 (en) | 2017-12-14 |
| JP6679624B2 (ja) | 2020-04-15 |
| CN107709340A (zh) | 2018-02-16 |
| US10233202B2 (en) | 2019-03-19 |
| CN106188139B (zh) | 2020-02-18 |
| JP2018517698A (ja) | 2018-07-05 |
| EP3305795A4 (en) | 2019-02-06 |
| IL255892B (en) | 2020-11-30 |
| CA2987473A1 (en) | 2016-12-08 |
| CN106188139A (zh) | 2016-12-07 |
| US20180127445A1 (en) | 2018-05-10 |
| RU2719594C2 (ru) | 2020-04-21 |
| SG11201709786WA (en) | 2017-12-28 |
| RU2017145357A (ru) | 2019-07-01 |
| ES2806726T3 (es) | 2021-02-18 |
| RU2017145357A3 (zh) | 2019-09-04 |
| TWI692479B (zh) | 2020-05-01 |
| EP3305795A1 (en) | 2018-04-11 |
| CN107709340B (zh) | 2020-03-17 |
| EP3305795B1 (en) | 2020-05-06 |
| TW201702246A (zh) | 2017-01-16 |
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