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GT201200066A - Nuevos derivados dihidro-oxazolobenzodiazepinonas, su procedimiento de preparación y las composiciones farmacéuticas que los contienen - Google Patents

Nuevos derivados dihidro-oxazolobenzodiazepinonas, su procedimiento de preparación y las composiciones farmacéuticas que los contienen

Info

Publication number
GT201200066A
GT201200066A GT201200066A GT201200066A GT201200066A GT 201200066 A GT201200066 A GT 201200066A GT 201200066 A GT201200066 A GT 201200066A GT 201200066 A GT201200066 A GT 201200066A GT 201200066 A GT201200066 A GT 201200066A
Authority
GT
Guatemala
Prior art keywords
oxazolobenzodiazepinonas
dihidro
derivatives
new
pharmaceutical compositions
Prior art date
Application number
GT201200066A
Other languages
English (en)
Inventor
István Ling
József Barkóczy
Ferenc Antoni
István Gacsályi
György Lévay
Michael Spedding
László Hársing
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GT201200066A publication Critical patent/GT201200066A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D245/00Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms
    • C07D245/04Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54Benzoxazoles; Hydrogenated benzoxazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

Abstract

LA PRESENTE INVENCIÓN SE REFIERE A NUEVOS DERIVADOS DIHIDRO-OXAZOLOBENZODIAZEPINONAS, SU PROCEDIMIENTO DE PREPARACIÓN Y LAS COMPOSICIONES FARMACÉUTICAS QUE LOS CONTIENEN.
GT201200066A 2011-03-08 2012-03-08 Nuevos derivados dihidro-oxazolobenzodiazepinonas, su procedimiento de preparación y las composiciones farmacéuticas que los contienen GT201200066A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1100682A FR2972454B1 (fr) 2011-03-08 2011-03-08 Nouveaux derives dihydro-oxazolobenzodiazepinones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
GT201200066A true GT201200066A (es) 2013-10-10

Family

ID=44004482

Family Applications (1)

Application Number Title Priority Date Filing Date
GT201200066A GT201200066A (es) 2011-03-08 2012-03-08 Nuevos derivados dihidro-oxazolobenzodiazepinonas, su procedimiento de preparación y las composiciones farmacéuticas que los contienen

Country Status (44)

Country Link
US (1) US8778932B2 (es)
EP (1) EP2497774B1 (es)
JP (1) JP5475816B2 (es)
KR (1) KR101477991B1 (es)
CN (1) CN102675341B (es)
AP (1) AP3344A (es)
AR (1) AR085691A1 (es)
AU (1) AU2012201031B2 (es)
BR (1) BR102012005137A2 (es)
CA (1) CA2771189C (es)
CL (1) CL2012000496A1 (es)
CR (1) CR20120109A (es)
CU (1) CU24134B1 (es)
CY (1) CY1114729T1 (es)
DK (1) DK2497774T3 (es)
EA (1) EA021125B1 (es)
EC (1) ECSP12011711A (es)
ES (1) ES2442293T3 (es)
FR (1) FR2972454B1 (es)
GE (1) GEP20146017B (es)
GT (1) GT201200066A (es)
HN (1) HN2012000485A (es)
HR (1) HRP20140050T1 (es)
IL (1) IL218215A (es)
JO (1) JO2948B1 (es)
MA (1) MA33641B1 (es)
MX (1) MX2012002788A (es)
MY (1) MY162537A (es)
NI (1) NI201200039A (es)
NZ (1) NZ598625A (es)
PE (1) PE20121682A1 (es)
PH (1) PH12012000035A1 (es)
PL (1) PL2497774T3 (es)
PT (1) PT2497774E (es)
RS (1) RS53032B (es)
RU (1) RU2572556C2 (es)
SA (2) SA112330331B1 (es)
SG (1) SG184633A1 (es)
SI (1) SI2497774T1 (es)
TW (1) TWI428342B (es)
UA (1) UA112153C2 (es)
UY (1) UY33927A (es)
WO (1) WO2012120206A1 (es)
ZA (1) ZA201201681B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU230684B1 (hu) * 2014-01-21 2017-08-28 Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag Új dihidro-oxazino-benzodiazepin vegyületek és eljárás ezek elõállítására, illetve az ezeket tartalmazó gyógyászati készítmények
DE102016005291B4 (de) 2016-04-29 2024-01-11 Ksg Austria Gmbh Verfahren zur Herstellung eines elektronischen Gerätes in der Form eines Spritzgußteils mit eingelegter Leiterplatte

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3370616D1 (en) 1982-08-06 1987-05-07 Ube Industries Process for producing phenylacetones
US5891871A (en) * 1996-03-21 1999-04-06 Cocensys, Inc. Substituted 2,3-benzodiazepin-4-ones and the use thereof
UA67749C2 (uk) * 1997-08-12 2004-07-15 Егіш Дьйодьсердьяр Рт. Похідна 8-заміщеного-9н-1,3-діоксол/4,5-h//2,3/бензодіазепіну з властивостями амра/каїнатного антагоніста, спосіб одержання похідних, фармацевтична композиція (варіанти), спосіб її одержання та спосіб лікування
SK1792000A3 (en) * 1997-08-12 2000-09-12 Egyt Gyogyszervegyeszeti Gyar 1,3-DIOXOLO(4,5-H)(2,3)BENZODIAZEPINE DERIVATIVES, PROCESS FORì (54) THE PREPARATION THEREOF, PHARMACEUTICAL COMPOSITION CO
GB9900222D0 (en) * 1999-01-06 1999-02-24 Merck Sharp & Dohme Therapeutic compounds
HU227128B1 (en) * 1999-07-07 2010-07-28 Egyt Gyogyszervegyeszeti Gyar New 2,3-benzodiazepine derivatives
CA2627757A1 (en) * 2005-10-26 2007-05-03 The Regents Of The University Of Michigan Therapeutic compositions and methods
HU230760B1 (hu) * 2005-12-30 2018-03-28 Egis Gyógyszergyár Nyilvánosan Működő Részvénytársaság Dihidro-2,3-benzodiazepin-származékok optikai izomerjei, eljárás ezek sztereoszelektív szintézisére, alkalmazásuk, az ezeket tartalmazó gyógyszerkészítmények és az eljárás közbenső termékei
EP2298296A1 (en) * 2009-08-25 2011-03-23 CNRS Centre National De La Recherche Scientifique Composition and method for treating cognitive impairments in down syndrome subjects

Also Published As

Publication number Publication date
PE20121682A1 (es) 2012-12-08
US20120232065A1 (en) 2012-09-13
PH12012000035A1 (en) 2013-09-09
AU2012201031B2 (en) 2015-05-07
SI2497774T1 (sl) 2014-02-28
AR085691A1 (es) 2013-10-23
ES2442293T3 (es) 2014-02-11
UY33927A (es) 2012-09-28
AP3344A (en) 2015-07-31
GEP20146017B (en) 2014-01-27
BR102012005137A2 (pt) 2015-06-16
RS53032B (sr) 2014-04-30
IL218215A (en) 2016-04-21
HN2012000485A (es) 2015-05-11
TWI428342B (zh) 2014-03-01
JP2012188422A (ja) 2012-10-04
CA2771189C (fr) 2014-06-10
EP2497774A1 (fr) 2012-09-12
TW201309708A (zh) 2013-03-01
SA112330231B1 (ar) 2014-12-01
RU2572556C2 (ru) 2016-01-20
CU20120041A7 (es) 2013-10-29
AU2012201031A1 (en) 2012-09-27
CU24134B1 (es) 2015-11-27
WO2012120206A1 (fr) 2012-09-13
JO2948B1 (en) 2016-03-15
AP2012006149A0 (en) 2012-04-30
MY162537A (en) 2017-06-15
EP2497774B1 (fr) 2013-10-16
DK2497774T3 (da) 2014-01-13
EA201200267A1 (ru) 2012-10-30
ECSP12011711A (es) 2012-07-31
UA112153C2 (uk) 2016-08-10
SA112330331B1 (ar) 2014-12-01
FR2972454A1 (fr) 2012-09-14
NZ598625A (en) 2013-06-28
MX2012002788A (es) 2012-09-07
IL218215A0 (en) 2012-07-31
JP5475816B2 (ja) 2014-04-16
CL2012000496A1 (es) 2014-07-18
CR20120109A (es) 2012-10-05
CN102675341A (zh) 2012-09-19
CY1114729T1 (el) 2016-10-05
EA021125B1 (ru) 2015-04-30
MA33641B1 (fr) 2012-10-01
SG184633A1 (en) 2012-10-30
KR101477991B1 (ko) 2014-12-31
FR2972454B1 (fr) 2013-03-01
PT2497774E (pt) 2013-11-26
KR20120102550A (ko) 2012-09-18
NI201200039A (es) 2012-11-09
US8778932B2 (en) 2014-07-15
RU2013144824A (ru) 2015-04-20
CA2771189A1 (fr) 2012-09-08
HK1176355A1 (en) 2013-07-26
PL2497774T3 (pl) 2014-03-31
ZA201201681B (en) 2012-11-28
CN102675341B (zh) 2015-02-25
HRP20140050T1 (hr) 2014-02-14

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