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GT200100184A - Amidas de acido fenilciclohexanocarboxilico sustituido y su uso. - Google Patents

Amidas de acido fenilciclohexanocarboxilico sustituido y su uso.

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Publication number
GT200100184A
GT200100184A GT200100184A GT200100184A GT200100184A GT 200100184 A GT200100184 A GT 200100184A GT 200100184 A GT200100184 A GT 200100184A GT 200100184 A GT200100184 A GT 200100184A GT 200100184 A GT200100184 A GT 200100184A
Authority
GT
Guatemala
Prior art keywords
amidas
fenilciclohexanocarboxilico
substituted acid
diseases
refers
Prior art date
Application number
GT200100184A
Other languages
English (en)
Inventor
Dr Erwin Bischoff
Dr Thomas Krahn
Dr Stephan-Nicholas Muller
Dr Holger Paulsen
Dr Joachim Schuhmacher
Dr Henning Steinhagen
Dr Wolfgang Thielemann
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GT200100184A publication Critical patent/GT200100184A/es

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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40—Acylated substituent nitrogen atom
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    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
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    • C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C233/63—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
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    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/12—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
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    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
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    • C07C235/40—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
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    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
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    • C07C271/16—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
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    • C07C271/20—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
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    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
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    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
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    • C07C2603/58—Ring systems containing bridged rings containing three rings
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Abstract

LA PRESENTE INVENCION SE REFIERE A AMIDAS DEL ACIDO FENILCICLOHEXANOCARBOXILICO SUSTITUIDAS DE FORMULA (I) DONDE R1, R2, R3, R4 Y A SON GRUPOS FUNCIONALES DESCRITOS EN EL EXPEDIENTE. TAMBIEN SE REFIERE A SU PROCEDIMIENTO DE PREPARACION Y A SU UTILIZACION EN MEDICAMENTOS, EN ESPECIAL PARA LA PREVENCION Y/O TRATAMIENTO DE ENFERMEDADES CARDIOVASCULARES TALES COMO POR EJEMPLO, ENFERMEDADES ISQUEMICAS AGUDAS Y CRONICAS.
GT200100184A 2000-09-11 2001-09-06 Amidas de acido fenilciclohexanocarboxilico sustituido y su uso. GT200100184A (es)

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DE10044792A DE10044792A1 (de) 2000-09-11 2000-09-11 Substituierte Phenylcyclohexancarbonsäureamide und ihre Verwendung

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US20040077618A1 (en) * 2002-10-22 2004-04-22 Bennani Youssef L. Cycloalkylamides and their therapeutic applications
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US20040122004A1 (en) 2004-06-24
MXPA03002047A (es) 2004-05-04
JP2004508350A (ja) 2004-03-18
SV2002000626A (es) 2002-10-24
PL360695A1 (en) 2004-09-20
WO2002020472A1 (de) 2002-03-14
US6649616B2 (en) 2003-11-18
CN1455767A (zh) 2003-11-12
ATE347544T1 (de) 2006-12-15
BR0113814A (pt) 2003-07-08
US20030008881A1 (en) 2003-01-09
HN2001000204A (es) 2001-10-25
US7074780B2 (en) 2006-07-11
KR20030029959A (ko) 2003-04-16
EP1318977B1 (de) 2006-12-06
AR030945A1 (es) 2003-09-03
UY26930A1 (es) 2002-04-26
CA2421781A1 (en) 2003-03-07
PE20020431A1 (es) 2002-06-08
DE10044792A1 (de) 2002-04-04
DE50111597D1 (de) 2007-01-18
EP1318977A1 (de) 2003-06-18
IL154633A0 (en) 2003-09-17
AU2002212176A1 (en) 2002-03-22

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