GR81486B - - Google Patents
Info
- Publication number
- GR81486B GR81486B GR74490A GR840174490A GR81486B GR 81486 B GR81486 B GR 81486B GR 74490 A GR74490 A GR 74490A GR 840174490 A GR840174490 A GR 840174490A GR 81486 B GR81486 B GR 81486B
- Authority
- GR
- Greece
- Prior art keywords
- carbon atoms
- image
- partial formula
- agent
- haloethynyl
- Prior art date
Links
- -1 2-tetrahydropyranyl Chemical group 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 229910002651 NO3 Inorganic materials 0.000 abstract 1
- NHNBFGGVMKEFGY-UHFFFAOYSA-N Nitrate Chemical compound [O-][N+]([O-])=O NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- HSFWRNGVRCDJHI-UHFFFAOYSA-N alpha-acetylene Natural products C#C HSFWRNGVRCDJHI-UHFFFAOYSA-N 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 125000001246 bromo group Chemical group Br* 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004980 cyclopropylene group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 239000012336 iodinating agent Substances 0.000 abstract 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical group II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- GGCZERPQGJTIQP-UHFFFAOYSA-N sodium;9,10-dioxoanthracene-2-sulfonic acid Chemical compound [Na+].C1=CC=C2C(=O)C3=CC(S(=O)(=O)O)=CC=C3C(=O)C2=C1 GGCZERPQGJTIQP-UHFFFAOYSA-N 0.000 abstract 1
- 150000003431 steroids Chemical class 0.000 abstract 1
- 125000000026 trimethylsilyl group Chemical group [H]C([H])([H])[Si]([*])(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0081—Substituted in position 17 alfa and 17 beta
- C07J1/0088—Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
- C07J1/0096—Alkynyl derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0081—Substituted in position 17 alfa and 17 beta
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0038—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an androstane skeleton, including 18- or 19-substituted derivatives, 18-nor derivatives and also derivatives where position 17-beta is substituted by a carbon atom not directly bonded to a further carbon atom and not being part of an amide group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
- C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Silicates, Zeolites, And Molecular Sieves (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19833315324 DE3315324A1 (de) | 1983-04-25 | 1983-04-25 | Verfahren zur herstellung von 17(alpha)-(br oder j)-ethinyl-17ss-or-steroiden |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR81486B true GR81486B (el) | 1984-12-11 |
Family
ID=6197529
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR74490A GR81486B (el) | 1983-04-25 | 1984-04-25 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4567002A (el) |
| EP (1) | EP0123241B1 (el) |
| JP (1) | JPS6034990A (el) |
| AT (1) | ATE41160T1 (el) |
| CA (1) | CA1254883A (el) |
| CS (1) | CS252474B2 (el) |
| DD (1) | DD221460A5 (el) |
| DE (2) | DE3315324A1 (el) |
| DK (1) | DK206684A (el) |
| ES (1) | ES8506045A1 (el) |
| FI (1) | FI841620A7 (el) |
| GR (1) | GR81486B (el) |
| HU (1) | HU193568B (el) |
| PL (1) | PL143460B1 (el) |
| SU (1) | SU1389681A3 (el) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3434448A1 (de) * | 1984-09-17 | 1986-03-27 | Schering AG, 1000 Berlin und 4709 Bergkamen | Verfahren zur herstellung von pregnan-derivaten |
| US5972922A (en) * | 1990-06-11 | 1999-10-26 | Alcon Laboratories, Inc. | Steroids which inhibit angiogenesis |
| EP0533703B1 (en) * | 1990-06-11 | 2000-03-15 | Alcon Laboratories, Inc. | Use of steroids for the inhibition of angiogenesis |
| HU210076B (en) * | 1992-11-02 | 1995-01-30 | Tuba | Process for producing androstane derivatives substituted with quaternisaeted amino group in 16-position and for producing pharmaceutical compositions containing them |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3211725A (en) * | 1960-04-20 | 1965-10-12 | Merck & Co Inc | 6alpha-methyl-21 halo nor ethisterones and intermediates in the preparation thereof |
| US3067214A (en) * | 1960-04-20 | 1962-12-04 | Merck & Co Inc | Haloethisterone compounds |
| US3347880A (en) * | 1962-10-05 | 1967-10-17 | Schering Corp | 17alpha-halogenoethinylestranes |
| DE2625306C2 (de) * | 1976-06-02 | 1978-06-15 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Verfahren zur Herstellung von Pregnan-Derivaten |
| DE3242892C1 (de) * | 1982-11-16 | 1984-07-12 | Schering AG, 1000 Berlin und 4709 Bergkamen | Verfahren zur Herstellung von 17alpha-(Br oder J)-ethinyl-17ss-hydroxysteroiden |
-
1983
- 1983-04-25 DE DE19833315324 patent/DE3315324A1/de not_active Withdrawn
-
1984
- 1984-04-14 EP EP84104258A patent/EP0123241B1/de not_active Expired
- 1984-04-14 DE DE8484104258T patent/DE3477000D1/de not_active Expired
- 1984-04-14 AT AT84104258T patent/ATE41160T1/de not_active IP Right Cessation
- 1984-04-23 SU SU843728751A patent/SU1389681A3/ru active
- 1984-04-23 DD DD84262213A patent/DD221460A5/de not_active IP Right Cessation
- 1984-04-24 PL PL1984247376A patent/PL143460B1/pl unknown
- 1984-04-24 HU HU841573A patent/HU193568B/hu not_active IP Right Cessation
- 1984-04-24 CA CA000452650A patent/CA1254883A/en not_active Expired
- 1984-04-25 JP JP59082111A patent/JPS6034990A/ja active Pending
- 1984-04-25 FI FI841620A patent/FI841620A7/fi not_active Application Discontinuation
- 1984-04-25 DK DK206684A patent/DK206684A/da not_active Application Discontinuation
- 1984-04-25 CS CS843070A patent/CS252474B2/cs unknown
- 1984-04-25 GR GR74490A patent/GR81486B/el unknown
- 1984-04-25 ES ES531900A patent/ES8506045A1/es not_active Expired
- 1984-04-25 US US06/603,855 patent/US4567002A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ES531900A0 (es) | 1985-07-01 |
| CS307084A2 (en) | 1987-01-15 |
| EP0123241B1 (de) | 1989-03-08 |
| CS252474B2 (en) | 1987-09-17 |
| DD221460A5 (de) | 1985-04-24 |
| HU193568B (en) | 1987-10-28 |
| PL143460B1 (en) | 1988-02-29 |
| DE3315324A1 (de) | 1984-10-31 |
| FI841620A0 (fi) | 1984-04-25 |
| JPS6034990A (ja) | 1985-02-22 |
| ES8506045A1 (es) | 1985-07-01 |
| SU1389681A3 (ru) | 1988-04-15 |
| ATE41160T1 (de) | 1989-03-15 |
| FI841620A7 (fi) | 1984-10-26 |
| CA1254883A (en) | 1989-05-30 |
| HUT34215A (en) | 1985-02-28 |
| DK206684A (da) | 1984-10-26 |
| US4567002A (en) | 1986-01-28 |
| PL247376A1 (en) | 1985-04-09 |
| DE3477000D1 (en) | 1989-04-13 |
| EP0123241A1 (de) | 1984-10-31 |
| DK206684D0 (da) | 1984-04-25 |
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