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GR77939B - - Google Patents

Info

Publication number
GR77939B
GR77939B GR70662A GR830170662A GR77939B GR 77939 B GR77939 B GR 77939B GR 70662 A GR70662 A GR 70662A GR 830170662 A GR830170662 A GR 830170662A GR 77939 B GR77939 B GR 77939B
Authority
GR
Greece
Prior art keywords
aspartyl
solubility
stability
methyl ester
relates
Prior art date
Application number
GR70662A
Other languages
English (en)
Inventor
Josef Hengkotsau
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of GR77939B publication Critical patent/GR77939B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A23L27/31—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives
    • A23L27/32—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives containing dipeptides or derivatives
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/801—Peptide sweetners

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Seasonings (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Parts Printed On Printed Circuit Boards (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)
  • Organic Insulating Materials (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
GR70662A 1982-03-04 1983-03-03 GR77939B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/354,574 US4448716A (en) 1982-03-04 1982-03-04 Dipeptide sweetener-metal complexes

Publications (1)

Publication Number Publication Date
GR77939B true GR77939B (el) 1984-09-25

Family

ID=23393964

Family Applications (1)

Application Number Title Priority Date Filing Date
GR70662A GR77939B (el) 1982-03-04 1983-03-03

Country Status (17)

Country Link
US (1) US4448716A (el)
EP (1) EP0088367B1 (el)
JP (1) JPS58162262A (el)
AT (1) ATE15752T1 (el)
AU (1) AU551602B2 (el)
CA (1) CA1248297A (el)
DE (1) DE3360859D1 (el)
DK (1) DK157724C (el)
ES (1) ES8504672A1 (el)
FI (1) FI77670C (el)
GR (1) GR77939B (el)
IE (1) IE54591B1 (el)
IL (1) IL68035A0 (el)
NO (1) NO161500C (el)
NZ (1) NZ203455A (el)
PT (1) PT76333B (el)
ZA (1) ZA831481B (el)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4692512A (en) * 1984-07-13 1987-09-08 The Procter & Gamble Company Alpha-L-aspartyl-D-phenylglycine esters and amides useful as high intensity sweeteners
EP0204826A4 (en) * 1984-12-11 1989-02-09 Patrick Joseph Joyce THERMOSTABLE PEPTIDE SWEETENERS.
US4676989A (en) * 1984-12-27 1987-06-30 General Foods Corporation Sweetening with cycloalkyl ethers and thioethers of dipeptides
EP0186173A3 (en) * 1984-12-27 1988-08-10 General Foods Corporation L-aminodicarboxylic-(0-cycloalkyl)-l-aminocarboxylate alkyl esters, an edible composition containing same as sweeteners and a method for sweetening an edible composition
WO1986003944A1 (en) * 1985-01-03 1986-07-17 Joyce Patrick J Heat stabilized peptide table salt substitutes
US4634792A (en) * 1985-05-06 1987-01-06 General Foods Corporation L-aminodicarboxylic acid aminoalkenoic acid ester amides
US4701552A (en) * 1985-05-06 1987-10-20 General Foods Corporation L-aminodicarboxylic acid alkanes
EP0236359A4 (en) * 1985-08-09 1987-11-23 Univ Georgia Res Found SWEETENING AGENTS WITH STABILIZED PEPTIDES.
US4663519A (en) * 1985-09-09 1987-05-05 At&T Company Wound coil products and manufacture thereof
US4692513A (en) * 1985-12-20 1987-09-08 The Procter & Gamble Company Alpha-L-aspartyl-D-heteroaromatic-substituted glycine esters and amides useful as high intensity sweeteners
US4830716B1 (en) * 1986-07-03 1999-12-07 Albion Int Preparation of pharmaceutical grade amino acid chelates
AU600176B2 (en) * 1987-10-13 1990-08-02 Mitsui Toatsu Chemicals Inc. Preparation method of alpha-l-aspartyl-l-phenylalanine methyl ester having improved solubilization
US4849541A (en) * 1987-11-13 1989-07-18 General Foods Corporation Process for the preparation of N-L-aminodicarboxylic acid esters and new compositions used in the preparation thereof
DE3831717A1 (de) * 1988-09-17 1990-03-22 Basf Ag Verfahren zur herstellung von dipeptiden mit n-terminalen nicht-proteinogenen aminosaeuren
DE69015387T2 (de) * 1989-03-08 1995-05-04 Pfizer Verhinderung der Geschmacksdegradation in bestimmten mit Alitamgesüssten Getränken.
JPH062582A (ja) * 1992-04-15 1994-01-11 Nippondenso Co Ltd 内燃機関の燃料噴射装置
GB2273130B (en) * 1992-12-07 1995-12-13 Nippon Denso Co Fuel injection system for multi-cylinder internal combustion engine
US6380163B1 (en) * 1992-12-22 2002-04-30 Baxter International Inc. Peritoneal dialysis solutions with polypeptides
US6129942A (en) * 1997-09-11 2000-10-10 The Nutrasweet Company Sweetener salts of N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester
US6146680A (en) * 1997-09-11 2000-11-14 The Nutrasweet Company Metal complexes of N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester
US6180156B1 (en) 1997-09-11 2001-01-30 The Nutrasweet Company Acid salts of N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester
US20030008047A1 (en) * 2000-03-17 2003-01-09 Schroeder Steve A. Stability enhancement of sweeteners using salts containing divalent or trivalent cations
CN101531702B (zh) * 2008-12-22 2011-12-21 华南理工大学 含卤素超甜二肽化合物及其制备方法与应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3492131A (en) * 1966-04-18 1970-01-27 Searle & Co Peptide sweetening agents
US4029701A (en) * 1972-03-30 1977-06-14 General Foods Corporation Sweetening with hydrohalide salts of dipeptide sweeteners
US4031258A (en) * 1972-03-30 1977-06-21 General Foods Corporation Inorganic salts of dipeptide sweeteners
GB1431057A (en) * 1972-03-30 1976-04-07 Gen Foods Corp Sweetining compositions
US4031259A (en) * 1975-08-13 1977-06-21 General Foods Corporation Process of preparing nutritive sweetening compositions
US4122195A (en) * 1977-01-24 1978-10-24 General Foods Corporation Fixation of APM in chewing gum

Also Published As

Publication number Publication date
AU551602B2 (en) 1986-05-08
FI77670C (fi) 1989-04-10
NO830727L (no) 1983-09-05
DE3360859D1 (en) 1985-10-31
ATE15752T1 (de) 1985-10-15
FI830726L (fi) 1983-09-05
NO161500C (no) 1989-08-23
CA1248297A (en) 1989-01-03
NO161500B (no) 1989-05-16
IE54591B1 (en) 1989-12-06
DK108083A (da) 1983-09-05
IE830459L (en) 1983-09-04
ES520274A0 (es) 1985-04-16
FI830726A0 (fi) 1983-03-03
PT76333A (en) 1983-04-01
JPS58162262A (ja) 1983-09-26
FI77670B (fi) 1988-12-30
ZA831481B (en) 1984-04-25
DK157724C (da) 1990-07-16
NZ203455A (en) 1985-12-13
AU1201383A (en) 1983-09-08
DK157724B (da) 1990-02-12
PT76333B (en) 1985-11-28
IL68035A0 (en) 1983-06-15
US4448716A (en) 1984-05-15
EP0088367B1 (en) 1985-09-25
ES8504672A1 (es) 1985-04-16
EP0088367A1 (en) 1983-09-14
DK108083D0 (da) 1983-03-03

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