GR76828B - - Google Patents
Info
- Publication number
- GR76828B GR76828B GR64701A GR810164701A GR76828B GR 76828 B GR76828 B GR 76828B GR 64701 A GR64701 A GR 64701A GR 810164701 A GR810164701 A GR 810164701A GR 76828 B GR76828 B GR 76828B
- Authority
- GR
- Greece
- Prior art keywords
- alkyl
- hydrogen
- phenyl
- substituted
- image
- Prior art date
Links
- 229910052739 hydrogen Inorganic materials 0.000 abstract 12
- 239000001257 hydrogen Substances 0.000 abstract 12
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 7
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 6
- -1 1-adamantyl Chemical group 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 3
- 150000002431 hydrogen Chemical class 0.000 abstract 3
- 125000000008 (C1-C10) alkyl group Chemical group 0.000 abstract 2
- 125000004448 alkyl carbonyl group Chemical group 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- 125000003837 (C1-C20) alkyl group Chemical group 0.000 abstract 1
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 1
- 125000000923 (C1-C30) alkyl group Chemical group 0.000 abstract 1
- 125000002941 2-furyl group Chemical group O1C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000004105 2-pyridyl group Chemical group N1=C([*])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000004485 2-pyrrolidinyl group Chemical group [H]N1C([H])([H])C([H])([H])C([H])([H])C1([H])* 0.000 abstract 1
- 125000000175 2-thienyl group Chemical group S1C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000003682 3-furyl group Chemical group O1C([H])=C([*])C([H])=C1[H] 0.000 abstract 1
- 125000003349 3-pyridyl group Chemical group N1=C([H])C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000004575 3-pyrrolidinyl group Chemical group [H]N1C([H])([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 abstract 1
- 125000001541 3-thienyl group Chemical group S1C([H])=C([*])C([H])=C1[H] 0.000 abstract 1
- 125000000339 4-pyridyl group Chemical group N1=C([H])C([H])=C([*])C([H])=C1[H] 0.000 abstract 1
- 125000000739 C2-C30 alkenyl group Chemical group 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004849 alkoxymethyl group Chemical group 0.000 abstract 1
- 125000005196 alkyl carbonyloxy group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol group Chemical group [C@@H]1(CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C)[C@H](C)CCCC(C)C HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 abstract 1
- 150000003839 salts Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
- C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
- Steroid Compounds (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/141,227 US4368190A (en) | 1980-04-17 | 1980-04-17 | Immunologically active dipeptidyl 4-O-,6-O-acyl-2-amino-2-deoxy-D-glucose derivatives and methods for their preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR76828B true GR76828B (el) | 1984-09-04 |
Family
ID=22494746
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR64701A GR76828B (el) | 1980-04-17 | 1981-04-15 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4368190A (el) |
| EP (1) | EP0038750B1 (el) |
| JP (1) | JPS56164196A (el) |
| AT (1) | ATE23537T1 (el) |
| CA (1) | CA1174232A (el) |
| DE (1) | DE3175602D1 (el) |
| DK (1) | DK172481A (el) |
| ES (1) | ES501457A0 (el) |
| GR (1) | GR76828B (el) |
| PT (1) | PT72866B (el) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR851293B (el) * | 1984-05-29 | 1985-11-25 | Ciba Geigy Ag | |
| US4640911A (en) * | 1985-05-29 | 1987-02-03 | Ciba-Geigy Corporation | Acylated sugar derivatives, processes for their manufacture, and their use |
| US4937077A (en) * | 1987-09-21 | 1990-06-26 | Eastman Kodak Company | Method for improving feed conversion of meat-producing animals by oral administration of 2-deoxy-D-hexose |
| US4866035A (en) * | 1987-10-05 | 1989-09-12 | Merck & Co., Inc. | Dipeptidyl saccharides as host resistance enhancers in AIDS-immuno-compromised hosts and methods of use |
| US6488929B2 (en) | 1994-05-23 | 2002-12-03 | Montana State University | Candida albicans phosphomannan complex as a vaccine |
| US6309642B1 (en) | 1997-04-28 | 2001-10-30 | The Research And Development Institute, Inc. | Peptides which mimic candida carbohydrate epitopes and their use in a vaccine |
| WO1995031998A1 (en) * | 1994-05-23 | 1995-11-30 | The Research & Development Institute, Inc. | Candida albicans adhesin as a vaccine |
| DE19631189A1 (de) * | 1996-08-02 | 1998-02-05 | Max Delbrueck Centrum | Neuartige kationische Amphiphile für den liposomalen Gentransfer |
| US20030072775A1 (en) * | 1997-04-28 | 2003-04-17 | The Research And Development Institute Inc. | Peptides which mimic candida carbohydrate epitopes and their use in a vaccine |
| CN1301847A (zh) * | 1999-12-27 | 2001-07-04 | 上海博德基因开发有限公司 | 一种新的多肽——脂肪氧化酶10和编码这种多肽的多核苷酸 |
| CN1313389A (zh) * | 2000-03-15 | 2001-09-19 | 上海博德基因开发有限公司 | 一种新的多肽——人脂肪氧化酶9和编码这种多肽的多核苷酸 |
| ES2733353T3 (es) | 2007-11-09 | 2019-11-28 | Basf As | Compuestos lípidos para uso en productos cosméticos, como suplemento alimenticio o como un medicamento |
| EP2147910A1 (en) * | 2008-07-15 | 2010-01-27 | Pronova BioPharma Norge AS | Novel lipid compounds |
| CN102459142B (zh) | 2009-05-08 | 2017-08-08 | 普罗诺瓦生物医药挪威公司 | 用于治疗与心血管、代谢和炎性疾病领域相关的疾病的多不饱和脂肪酸 |
| NZ600608A (en) | 2009-12-18 | 2015-01-30 | Idenix Pharmaceuticals Inc | 5,5-fused arylene or heteroarylene hepatitis c virus inhibitors |
| SG10201509127YA (en) | 2010-11-05 | 2015-12-30 | Pronova Biopharma Norge As | Methods of treatment using lipid compounds |
| ES2748562T3 (es) | 2013-02-28 | 2020-03-17 | Basf As | Una composición que comprende un compuesto lipídico, un triglicérido y un tensioactivo, y procedimientos de uso de la misma |
| CN107530306A (zh) | 2015-04-28 | 2018-01-02 | 普罗诺瓦生物医药挪威公司 | 结构增强的含硫脂肪酸在预防和/或治疗非酒精性脂肪性肝炎中的用途 |
| IL275002B2 (en) | 2017-12-06 | 2024-04-01 | Basf As | Fatty acid derivatives for treating non-alcoholic steatohepatitis |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2288527A2 (fr) | 1974-10-22 | 1976-05-21 | Anvar | Compositions contenant de la n-acetyl-muramyl- l-alanyl - d-isoglutamine ou de l'acide n-acetyl-muramyl-l-alanyl - d-glutamique, exemptes d'huile et ayant des proprietes adjuvantes |
| SE7607300L (sv) | 1975-08-13 | 1977-02-14 | Kefalas As | Tiaxantenforeningar samt forfarande for framstellning av dem |
| CH613709A5 (en) * | 1975-12-10 | 1979-10-15 | Ciba Geigy Ag | Process for the preparation of glucosamine derivatives |
| US4082735A (en) * | 1976-04-26 | 1978-04-04 | Syntex (U.S.A.) Inc. | Novel immunological adjuvant compounds and methods of preparation thereof |
| GB1571133A (en) * | 1976-04-26 | 1980-07-09 | Syntex Inc | Immuniological adjuvant peptidoglycans compounds and methods of preparation thereof |
| US4082736A (en) * | 1976-04-26 | 1978-04-04 | Syntex (U.S.A.) Inc. | Novel immunological adjuvant compounds and methods of preparation thereof |
| JPS5479227A (en) * | 1977-12-02 | 1979-06-25 | Takeda Chem Ind Ltd | Glucosamine derivative and its preparation |
| EP0002677B1 (en) * | 1977-12-02 | 1982-10-13 | Takeda Chemical Industries, Ltd. | Glucosamine-peptide derivatives and their pharmaceutical compositions |
| JPS5479228A (en) * | 1977-12-02 | 1979-06-25 | Takeda Chem Ind Ltd | Glucosamine derivative and its preparation |
| CA1138436A (en) * | 1978-02-24 | 1982-12-28 | Gerhard Baschang | Process for the manufacture of novel antigens |
| FR2442241A2 (fr) * | 1978-03-20 | 1980-06-20 | Anvar | Nouveaux composes esters de muramyl-peptide, leur preparation et les compositions pharmaceutiques les contenant, notamment sous forme de liposomes |
| JPS54130517A (en) * | 1978-03-31 | 1979-10-09 | Yuuichi Yamamura | Muramyldipeptide higher fatty acid ester |
| HU186585B (en) * | 1978-05-18 | 1985-08-28 | Ciba Geigy Ag | Process for producing new muramil-peptide derivatives |
| FR2428051A1 (fr) * | 1978-06-05 | 1980-01-04 | Anvar | Nouveaux composes du type muramyl-peptide et medicaments les contenant |
| FR2449697A1 (fr) * | 1979-02-20 | 1980-09-19 | Anvar | Nouveaux muramyl-peptides substitues sur un azote peptidique et medicaments les contenant |
| JPS55111499A (en) * | 1979-02-21 | 1980-08-28 | Takeda Chem Ind Ltd | Glucosamine derivative and its preparation |
-
1980
- 1980-04-17 US US06/141,227 patent/US4368190A/en not_active Expired - Lifetime
-
1981
- 1981-04-15 DK DK172481A patent/DK172481A/da active IP Right Grant
- 1981-04-15 AT AT81400608T patent/ATE23537T1/de not_active IP Right Cessation
- 1981-04-15 PT PT72866A patent/PT72866B/pt unknown
- 1981-04-15 GR GR64701A patent/GR76828B/el unknown
- 1981-04-15 CA CA000375513A patent/CA1174232A/en not_active Expired
- 1981-04-15 EP EP81400608A patent/EP0038750B1/en not_active Expired
- 1981-04-15 ES ES501457A patent/ES501457A0/es active Granted
- 1981-04-15 DE DE8181400608T patent/DE3175602D1/de not_active Expired
- 1981-04-17 JP JP5725981A patent/JPS56164196A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0038750B1 (en) | 1986-11-12 |
| US4368190A (en) | 1983-01-11 |
| PT72866B (en) | 1985-11-25 |
| EP0038750A1 (en) | 1981-10-28 |
| ES8207553A1 (es) | 1982-09-16 |
| JPS56164196A (en) | 1981-12-17 |
| PT72866A (en) | 1981-05-01 |
| DK172481A (da) | 1981-10-18 |
| CA1174232A (en) | 1984-09-11 |
| ES501457A0 (es) | 1982-09-16 |
| DE3175602D1 (en) | 1987-01-02 |
| ATE23537T1 (de) | 1986-11-15 |
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