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GR35044B - Μεθοδος παρασκευης οργανικων ενωσεων. - Google Patents

Μεθοδος παρασκευης οργανικων ενωσεων.

Info

Publication number
GR35044B
GR35044B GR670135044A GR670135044A GR35044B GR 35044 B GR35044 B GR 35044B GR 670135044 A GR670135044 A GR 670135044A GR 670135044 A GR670135044 A GR 670135044A GR 35044 B GR35044 B GR 35044B
Authority
GR
Greece
Prior art keywords
formula
preparation
organic compounds
azepine
benzoyl
Prior art date
Application number
GR670135044A
Other languages
English (en)
Original Assignee
The Upjohn Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Upjohn Company filed Critical The Upjohn Company
Publication of GR35044B publication Critical patent/GR35044B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/08—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/12—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Indole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

ία μέθοδος δια την παραγωγήν μιας ενώσεως του τύπου [*] εις τον οποίον το Ο είναι φαινύλιον και ειςτο οποίον τα R και R1 εκλέγονται από την ομάδα την αποτελουμένην από υδρογόνον αλκοξύ, και αλκύλιονπεριέχον από 1-3 άτομα άνθρακος, περιλαμβανόμενα και αλογόνον, η οποία περιλαμβάνει: την θέρμανσιν μιας φαινυλυδραζίνης του τύπου Ι: [*] εις τον οποίον τα R και R1 έχουν σημασίαν, την ανωτέρω, με το 1-βενζοϋλ-εξαϋδρο-4Η-αζεπίνη-4-εν δια την λήψιν της αντιστοίχου φαινυλυδραζόνης του 1-βενζοϋλεξαϋδρο-4Η-αζεπίνη-4- εν του τύπου ΙΙ: [*] εις τον οποίοντα R, R1 και Ο έχουν την αυτήν σημασίαν όπως ανωτέρω και θέρμανσιν της ενώσεως ταύτης μεεμυρμηκικόνοξύ δια την λήψιν του αντιστοίχου 3-βενζοϋλο-1,2,3,4,5,6-εξαϋδροαζεπινο [4,5-b] ινδολίου τουτύπου ΙΙΙ ανωτέρω.
GR670135044A 1966-05-10 1967-04-10 Μεθοδος παρασκευης οργανικων ενωσεων. GR35044B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US54888066A 1966-05-10 1966-05-10

Publications (1)

Publication Number Publication Date
GR35044B true GR35044B (el) 1968-07-31

Family

ID=24190763

Family Applications (1)

Application Number Title Priority Date Filing Date
GR670135044A GR35044B (el) 1966-05-10 1967-04-10 Μεθοδος παρασκευης οργανικων ενωσεων.

Country Status (9)

Country Link
BE (1) BE698268A (el)
CH (1) CH506543A (el)
DE (1) DE1695943A1 (el)
ES (1) ES340258A1 (el)
FR (1) FR6699M (el)
GB (2) GB1180615A (el)
GR (1) GR35044B (el)
IL (2) IL27776A (el)
NL (1) NL6706513A (el)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2434166A2 (fr) * 1978-08-24 1980-03-21 Omnium Chimique Sa Procede de preparation de vincadifformine et derives similaires
FR2663935A1 (fr) * 1990-06-27 1992-01-03 Adir Nouveaux 1,2,3,4,5,6-hexahydroazepino [4,5-b] indoles et 1,2,3,4-tetrahydrobethacarbolines, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
US7030109B2 (en) 1999-07-19 2006-04-18 Pharmacia & Upjohn Company 1,2,3,4,5,6-Hexahydroazepino[4,5-b]indoles containing arylsulfones at the 9-position
MY122278A (en) 1999-07-19 2006-04-29 Upjohn Co 1,2,3,4,5,6-hexahydroazepino[4,5-b]indoles containing arylsulfones at the 9-position
WO2002004456A1 (en) * 2000-07-06 2002-01-17 Pharmacia & Upjohn Company SUBSTITUTED 2,3,7,8,9,10,11,12-OCTAHYDROAZEPINO[4,5-b]PYRANO[3,2-e]INDOLES
AR035493A1 (es) 2000-09-20 2004-06-02 Upjohn Co Derivados de azepino (4,5b) indolina sustituidos, composicion farmaceutica y el uso de dichos derivados para preparar un medicamento
US7595311B2 (en) 2002-05-24 2009-09-29 Exelixis, Inc. Azepinoindole derivatives as pharmaceutical agents
TWI329111B (en) 2002-05-24 2010-08-21 X Ceptor Therapeutics Inc Azepinoindole and pyridoindole derivatives as pharmaceutical agents
AU2004259009A1 (en) * 2003-07-23 2005-02-03 Exelixis, Inc. Azepine derivatives as pharmaceutical agents
WO2023092045A1 (en) 2021-11-17 2023-05-25 Terran Biosciences, Inc. Salt and solid forms of tabernanthalog

Also Published As

Publication number Publication date
NL6706513A (el) 1967-11-13
CH506543A (de) 1971-04-30
FR6699M (el) 1969-02-10
IL36801A (en) 1971-11-29
GB1180616A (en) 1970-02-04
ES340258A1 (es) 1968-06-01
GB1180615A (en) 1970-02-04
BE698268A (el) 1967-11-10
DE1695943A1 (de) 1971-05-13
IL27776A (en) 1971-11-29

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