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GR3036622T3 - Preserved ophthalmic drug compositions containing polymeric quaternary ammonium compounds - Google Patents

Preserved ophthalmic drug compositions containing polymeric quaternary ammonium compounds

Info

Publication number
GR3036622T3
GR3036622T3 GR20010401480T GR20010401480T GR3036622T3 GR 3036622 T3 GR3036622 T3 GR 3036622T3 GR 20010401480 T GR20010401480 T GR 20010401480T GR 20010401480 T GR20010401480 T GR 20010401480T GR 3036622 T3 GR3036622 T3 GR 3036622T3
Authority
GR
Greece
Prior art keywords
quaternary ammonium
compositions containing
ammonium compounds
polymeric quaternary
containing polymeric
Prior art date
Application number
GR20010401480T
Other languages
English (en)
Inventor
Suketu Dipakbhai Desai
Diane S Nelms
Original Assignee
Alcon Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Lab Inc filed Critical Alcon Lab Inc
Publication of GR3036622T3 publication Critical patent/GR3036622T3/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GR20010401480T 1994-11-16 2001-09-17 Preserved ophthalmic drug compositions containing polymeric quaternary ammonium compounds GR3036622T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/340,763 US5603929A (en) 1994-11-16 1994-11-16 Preserved ophthalmic drug compositions containing polymeric quaternary ammonium compounds
PCT/US1995/014910 WO1996014829A1 (en) 1994-11-16 1995-11-16 Preserved ophthalmic drug compositions containing polymeric quaternary ammonium compounds

Publications (1)

Publication Number Publication Date
GR3036622T3 true GR3036622T3 (en) 2001-12-31

Family

ID=23334841

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20010401480T GR3036622T3 (en) 1994-11-16 2001-09-17 Preserved ophthalmic drug compositions containing polymeric quaternary ammonium compounds

Country Status (12)

Country Link
US (2) US5603929A (el)
EP (1) EP0739197B1 (el)
JP (1) JP2954356B2 (el)
AT (1) ATE203897T1 (el)
AU (1) AU686917B2 (el)
CA (1) CA2180554C (el)
DE (1) DE69522094T2 (el)
DK (1) DK0739197T3 (el)
ES (1) ES2160722T3 (el)
GR (1) GR3036622T3 (el)
PT (1) PT739197E (el)
WO (1) WO1996014829A1 (el)

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US5505953A (en) * 1992-05-06 1996-04-09 Alcon Laboratories, Inc. Use of borate-polyol complexes in ophthalmic compositions
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NZ336031A (en) * 1996-12-13 2000-05-26 Alcon Lab Inc Ophthalmic composition with an amino alcohol molecular weight from 60 to 200 and borate composition; method of enhancing anti-microbial activity with composition
PT999825E (pt) 1997-07-29 2004-02-27 Alcon Lab Inc Composicoes oftalmicas contendo polimeros de galactomanano e borato
WO1999027060A1 (en) 1997-11-26 1999-06-03 Allergan Sales, Inc. Contact lens cleaning compositions
US6063745A (en) 1997-11-26 2000-05-16 Allergan Mutli-purpose contact lens care compositions
JPH11249087A (ja) * 1997-12-18 1999-09-17 Tome:Kk コンタクトレンズ用液剤
JP2006111636A (ja) * 1997-12-26 2006-04-27 Astellas Pharma Inc 徐放性医薬組成物
US7678836B2 (en) * 1999-11-04 2010-03-16 Fxs Ventures, Llc Method for rendering a contact lens wettable
ATE291913T1 (de) * 2000-01-25 2005-04-15 Alcon Inc Antiallergische ophthalmische zubereitungen, geeignet zur anwendung mit kontaktlinsen
AR035509A1 (es) * 2000-12-21 2004-06-02 Alcon Inc Solucion de lagrimas artificiales mejorada que contiene una combinacion de tres emolientes y el uso de dicha solucion para la fabricacion de un medicamento
US7923469B2 (en) * 2001-04-30 2011-04-12 Allergen, Inc. Compositions including vitamin-based surfactants and methods for using same
JP4286480B2 (ja) * 2001-09-17 2009-07-01 株式会社メニコン 殺菌液
ATE393627T1 (de) 2003-01-21 2008-05-15 Senju Pharma Co Wässrige flüssige zubereitung mit 2-amino-3-(4- bromobenzoyl)phenylessigsäure
CA2505836C (en) * 2004-05-06 2013-08-27 Alcon Inc. Topical brimonidine tartrate formulations that lack chlorine dioxide
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MX2007001172A (es) * 2004-11-05 2007-03-12 Senju Pharma Co Gotas acuosas para ojos que promueven la penetracion intraocular.
JP5108234B2 (ja) * 2005-02-07 2012-12-26 日本特殊陶業株式会社 マイクロヒータ及びセンサ
US7947010B2 (en) * 2005-07-08 2011-05-24 Depuy Products, Inc. Composition and system for wound decontamination
US20100130580A1 (en) * 2006-01-25 2010-05-27 Aciex Therapeutics, Inc. Formulations and Methods for Treating Dry Eye
US20090010850A1 (en) * 2007-05-24 2009-01-08 Ousler Iii George W Formulations and methods for treating dry eye
CA2621616A1 (en) * 2007-02-19 2008-08-19 Alcon Research, Ltd. Topical gatifloxacin formulations
US7705112B2 (en) * 2007-04-17 2010-04-27 Abbott Medical Optics Inc. Polyquaternium-1 synthesis methods
EP2197461B1 (en) 2007-10-08 2018-02-21 Aurinia Pharmaceuticals Inc. Ophthalmic compositions comprising calcineurin inhibitors or mtor inhibitors
CN101965183A (zh) * 2008-02-21 2011-02-02 伊斯塔药品公司 作为佐剂的眼用nsaid
RU2431469C1 (ru) * 2008-03-03 2011-10-20 Аллерган, Инк. Композиции кеторолака трометамина для лечения или профилактики глазной боли
US9192571B2 (en) 2008-03-03 2015-11-24 Allergan, Inc. Ketorolac tromethamine compositions for treating or preventing ocular pain
AU2009225931B9 (en) 2008-03-17 2014-04-03 Novartis Ag Aqueous pharmaceutical compositions containing borate-polyol complexes
TWI544927B (zh) 2008-03-17 2016-08-11 愛爾康研究有限公司 具有低濃度的表面活性劑以促進治療劑之生物可利用性的藥學組成物
TWI454289B (zh) * 2008-04-03 2014-10-01 Alcon Res Ltd 使用順式二醇的聚合物於抑制陽離子殺生物劑被吸收進入水凝膠生物材質中之用途
TW201038295A (en) 2009-04-17 2010-11-01 Alcon Res Ltd Aqueous ophthalmic compositions containing anionic therapeutic agents
JP2012529509A (ja) 2009-06-09 2012-11-22 ラックス・バイオサイエンシーズ・インコーポレイテッド 眼科用用途のための局所薬物送達システム
TWI489997B (zh) 2009-06-19 2015-07-01 Alcon Res Ltd 含有硼酸－多元醇錯合物之水性藥學組成物
KR102075173B1 (ko) 2011-01-18 2020-02-07 센주 세이야꾸 가부시키가이샤 보존 효력을 갖는 브롬페낙 수성 액제 조성물
ES2664053T3 (es) * 2012-11-19 2018-04-18 Bausch & Lomb Incorporated Composición líquida acuosa que contiene ácido 2-amino-3-(4-bromobenzoil)fenil-láctico
EP3010485A1 (en) 2013-06-19 2016-04-27 Sentiss Research Center Stable bromfenac solution
WO2015026548A1 (en) 2013-08-20 2015-02-26 3M Innovative Properties Company Boron-silane polyether complex
WO2015087267A2 (en) 2013-12-12 2015-06-18 Sentiss Pharma Private Limited Stable bromfenac ophthalmic solution
US10632202B2 (en) 2016-03-04 2020-04-28 Johnson & Johnson Consumer Inc. Preservative containing compositions
US20190224275A1 (en) 2017-05-12 2019-07-25 Aurinia Pharmaceuticals Inc. Protocol for treatment of lupus nephritis
US20230159202A1 (en) * 2021-11-23 2023-05-25 Bausch + Lomb Ireland Limited Method for making a preservative-free packaged ophthalmic device product

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US3931319A (en) * 1974-10-29 1976-01-06 Millmaster Onyx Corporation Capped polymers
US4136173A (en) * 1977-01-31 1979-01-23 American Home Products Corp. Mixed xanthan gum and locust beam gum therapeutic compositions
US4136178A (en) * 1977-01-31 1979-01-23 American Home Products Corp. Locust bean gum therapeutic compositions
US4136177A (en) * 1977-01-31 1979-01-23 American Home Products Corp. Xanthan gum therapeutic compositions
FR2508440B1 (fr) * 1981-06-25 1985-11-08 Saint Gobain Isover Procede de preparation d'alcools orthohydroxybenzyliques
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US4525346A (en) * 1981-09-28 1985-06-25 Alcon Laboratories, Inc. Aqueous antimicrobial ophthalmic solutions
US4836986A (en) * 1984-09-28 1989-06-06 Bausch & Lomb Incorporated Disinfecting and preserving systems and methods of use
FR2588189B1 (fr) * 1985-10-03 1988-12-02 Merck Sharp & Dohme Composition pharmaceutique de type a transition de phase liquide-gel
US4822819A (en) * 1986-11-07 1989-04-18 Alcon Laboratories, Inc. Use of trimoprostil and derivatives in glaucoma therapy
US4822820A (en) * 1986-11-24 1989-04-18 Alcon Laboratories, Inc. Use of tri-methyl PG-F2 a and derivatives in glaucoma therapy
US5110493A (en) * 1987-09-11 1992-05-05 Syntex (U.S.A.) Inc. Ophthalmic NSAID formulations containing a quaternary ammonium preservative and a nonionic surfactant
FI94924C (fi) * 1987-09-11 1995-11-27 Syntex Inc Menetelmä antimikrobisesti vaikuttavan säilytyssysteemin valmistamiseksi oftalmologisesti hyväksyttäviä lääkeaineita varten
IE63392B1 (en) * 1988-02-08 1995-04-19 Insite Vision Inc Ophthalmic suspensions
US5188826A (en) * 1988-02-08 1993-02-23 Insite Vision Incorporated Topical ophthalmic suspensions
US5149693A (en) * 1988-03-09 1992-09-22 Alcon Laboratories, Inc. Combination of tobramycin and fluorometholone for topical ophthalmic use
US5149694A (en) * 1988-03-09 1992-09-22 Alcon Laboratories, Inc. Combination of tobramycin and dexamethasone for topical ophthalmic use
US5173507A (en) * 1988-07-18 1992-12-22 Alcon Laboratories, Inc. Prostaglandin combinations in glaucoma therapy
US4960799A (en) * 1988-09-13 1990-10-02 Ciba-Geigy Corporation Stabilized aqueous solutions of pharmaceutically acceptable salts of ortho-(2,6-dichlorophenyl)-aminophenylacetic acid for opthalmic use
US5037647A (en) * 1988-09-15 1991-08-06 Alcon Laboratories, Inc. Aqueous antimicrobial opthalmic solutions comprised of quaternary ammonium compound, citric acid, citrate and sodium chloride
US5145643A (en) * 1990-01-05 1992-09-08 Allergan, Inc. Nonoxidative ophthalmic compositions and methods for preserving and using same
ATE300936T1 (de) * 1992-05-06 2005-08-15 Alcon Lab Inc Anwendung von boral-polyol-komplexen für ophthalmische arzneizusammensetzungen
US5300287A (en) * 1992-11-04 1994-04-05 Alcon Laboratories, Inc. Polymeric antimicrobials and their use in pharmaceutical compositions
AU6021794A (en) * 1993-01-11 1994-08-15 Allergan, Inc. Ophthalmic compositions comprising benzyllauryldimethylammonium chloride

Also Published As

Publication number Publication date
US5653972A (en) 1997-08-05
DK0739197T3 (da) 2001-10-29
WO1996014829A1 (en) 1996-05-23
EP0739197B1 (en) 2001-08-08
DE69522094T2 (de) 2001-11-22
ATE203897T1 (de) 2001-08-15
CA2180554C (en) 2001-08-21
HK1012556A1 (en) 1999-08-06
DE69522094D1 (de) 2001-09-13
JPH09503791A (ja) 1997-04-15
PT739197E (pt) 2001-12-28
CA2180554A1 (en) 1996-05-23
ES2160722T3 (es) 2001-11-16
US5603929A (en) 1997-02-18
JP2954356B2 (ja) 1999-09-27
AU686917B2 (en) 1998-02-12
EP0739197A1 (en) 1996-10-30
AU4162296A (en) 1996-06-06

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