GR3035849T3 - Diphenylmethylene piperidine derivatives - Google Patents

Diphenylmethylene piperidine derivatives

Info

Publication number: GR3035849T3
Authority: GR; Greece
Prior art keywords: piperidine derivatives; diphenylmethylene piperidine; diphenylmethylene; derivatives; piperidine
Prior art date: 1995-07-12

Application number

GR20010400699T

Other languages

English (en)

Inventor

Duncan Robertson Rae

David Robert Jaap

Original Assignee

Akzo Nobel Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-07-12

Filing date

2001-05-11

Publication date

2001-08-31

2001-05-11 Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv

2001-08-31 Publication of GR3035849T3 publication Critical patent/GR3035849T3/el

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Plural Heterocyclic Compounds (AREA)

GR20010400699T 1995-07-12 2001-05-11 Diphenylmethylene piperidine derivatives GR3035849T3 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP95201910		1995-07-12
EP96927006A EP0842170B1 (en)	1995-07-12	1996-07-09	Diphenylmethylene piperidine derivatives
PCT/EP1996/003099 WO1997003065A1 (en)	1995-07-12	1996-07-09	Diphenylmethylene piperidine derivatives

Publications (1)

Publication Number	Publication Date
GR3035849T3 true GR3035849T3 (en)	2001-08-31

Family

ID=8220478

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
GR20010400699T GR3035849T3 (en)	1995-07-12	2001-05-11	Diphenylmethylene piperidine derivatives

Country Status (26)

Country	Link
US (1)	US5935974A (el)
EP (1)	EP0842170B1 (el)
JP (1)	JPH11508907A (el)
KR (1)	KR19990028807A (el)
CN (1)	CN1091108C (el)
AR (1)	AR003966A1 (el)
AT (1)	ATE199150T1 (el)
AU (1)	AU699370B2 (el)
BR (1)	BR9609330A (el)
CA (1)	CA2226851A1 (el)
CZ (1)	CZ288909B6 (el)
DE (1)	DE69611788T2 (el)
DK (1)	DK0842170T3 (el)
ES (1)	ES2156287T3 (el)
GR (1)	GR3035849T3 (el)
HU (1)	HUP9802762A3 (el)
IL (1)	IL118768A (el)
NO (1)	NO309765B1 (el)
NZ (1)	NZ315318A (el)
PL (1)	PL183837B1 (el)
PT (1)	PT842170E (el)
RU (1)	RU2162846C2 (el)
TR (1)	TR199800027T1 (el)
TW (1)	TW419477B (el)
WO (1)	WO1997003065A1 (el)
ZA (1)	ZA965691B (el)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR20010024441A (ko) *	1997-10-07	2001-03-26	에프.지.엠. 헤르만스	항정신병성의 치환된 피페리딘 유도체
WO1999034799A1 (en) *	1998-01-09	1999-07-15	Akzo Nobel N.V.	Use of diphenylmethylene piperidine derivatives in the manufacture of a medicament for the treatment of movement disorders
WO1999034801A1 (en) *	1998-01-09	1999-07-15	Akzo Nobel N.V.	Use of diphenylmethylene piperidine derivatives in the manufacture of a medicament for the treatment of depression
US6538002B1 (en)	1999-06-11	2003-03-25	Merck & Co., Inc.	Cyclopentyl modulators of chemokine receptor activity
AU5600100A (en)	1999-06-11	2001-01-02	Merck & Co., Inc.	Cyclopentyl modulators of chemokine receptor activity
US6500844B1 (en)	1999-06-11	2002-12-31	Merck & Co., Inc.	Cyclopentyl modulators of chemokine receptor activity
US6472410B1 (en)	1999-06-11	2002-10-29	Merck & Co., Inc.	N-cyclopentyl modulators of chemokine receptor activity
US6358979B1 (en)	1999-06-11	2002-03-19	Merck & Co., Inc.	N-cyclopentyl modulators of chemokine receptor activity
WO2000076513A1 (en)	1999-06-11	2000-12-21	Merck & Co., Inc.	Cyclopentyl modulators of chemokine receptor activity
KR20010113007A (ko) *	2000-06-15	2001-12-24	주정호	항암제로서 유용한 ｎ-치환된 피페리디닐우레아 유도체 및그의 제조방법
TW200303304A (en) *	2002-02-18	2003-09-01	Astrazeneca Ab	Chemical compounds
US6770659B2 (en) *	2002-08-26	2004-08-03	Sk Corporation	Benzoyl piperidine compounds
CN100400519C (zh) *	2002-12-18	2008-07-09	拜尔农科股份公司	N-(取代的芳基甲基)-4-(二取代的甲基)哌啶和哌嗪
SE0400208D0 (sv) *	2004-02-02	2004-02-02	Astrazeneca Ab	Chemical compounds
TW200812582A (en) *	2006-04-06	2008-03-16	Astrazeneca Ab	Medicaments
SG11201701315VA (en)	2014-08-28	2017-03-30	Asceneuron Sa	Glycosidase inhibitors
DK3389658T3 (da) *	2015-12-18	2021-01-11	Merck Sharp & Dohme	Glycosidasehæmmere og anvendelser deraf
AU2017222962B2 (en)	2016-02-25	2021-03-25	Asceneuron S. A.	Acid addition salts of piperazine derivatives
US11261183B2 (en)	2016-02-25	2022-03-01	Asceneuron Sa	Sulfoximine glycosidase inhibitors
EP3419971B1 (en)	2016-02-25	2022-04-20	Asceneuron SA	Glycosidase inhibitors
CN108884078A (zh)	2016-02-25	2018-11-23	阿森纽荣股份公司	糖苷酶抑制剂
EP3672959A1 (en)	2017-08-24	2020-07-01	Asceneuron SA	Linear glycosidase inhibitors
WO2020039028A1 (en)	2018-08-22	2020-02-27	Asceneuron S. A.	Tetrahydro-benzoazepine glycosidase inhibitors
WO2020039027A1 (en)	2018-08-22	2020-02-27	Asceneuron S. A.	Pyrrolidine glycosidase inhibitors
WO2020039029A1 (en)	2018-08-22	2020-02-27	Asceneuron S. A.	Spiro compounds as glycosidase inhibitors
MX2021002111A (es)	2018-08-22	2021-07-16	Asceneuron S A	Sales de adición de ácido de succinato y fumarato de derivados de piperazina útiles como inhibidores de glucosidasa.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US450780A (en) *		1891-04-21		Steam-engine
US4180583A (en) *	1972-01-28	1979-12-25	Richardson-Merrell Inc.	Olefinic 4-substituted piperidino derivatives as therapeutics
US3922276A (en) *	1974-12-11	1975-11-25	Robins Co Inc A H	1-Substituted-4-benzylidenepiperidines
US4666905A (en) *	1983-06-02	1987-05-19	Warner-Lambert Company	Diphenylmethylene piperidines compositions and methods for their use
US4540780A (en) *	1983-06-02	1985-09-10	Warner-Lambert Company	Diphenylmethylene piperidines
MX173362B (es) *	1987-03-02	1994-02-23	Pfizer	Compuestos de piperazinil heterociclicos y procedimiento para su preparacion

1996
- 1996-07-01 IL IL11876896A patent/IL118768A/xx not_active IP Right Cessation
- 1996-07-04 ZA ZA965691A patent/ZA965691B/xx unknown
- 1996-07-09 CN CN96195461A patent/CN1091108C/zh not_active Expired - Fee Related
- 1996-07-09 CZ CZ199883A patent/CZ288909B6/cs not_active IP Right Cessation
- 1996-07-09 EP EP96927006A patent/EP0842170B1/en not_active Expired - Lifetime
- 1996-07-09 DE DE69611788T patent/DE69611788T2/de not_active Expired - Fee Related
- 1996-07-09 RU RU98102392/04A patent/RU2162846C2/ru not_active IP Right Cessation
- 1996-07-09 JP JP9505516A patent/JPH11508907A/ja active Pending
- 1996-07-09 HU HU9802762A patent/HUP9802762A3/hu unknown
- 1996-07-09 AT AT96927006T patent/ATE199150T1/de not_active IP Right Cessation
- 1996-07-09 NZ NZ315318A patent/NZ315318A/en unknown
- 1996-07-09 TR TR1998/00027T patent/TR199800027T1/xx unknown
- 1996-07-09 PL PL96324451A patent/PL183837B1/pl unknown
- 1996-07-09 BR BR9609330A patent/BR9609330A/pt active Search and Examination
- 1996-07-09 ES ES96927006T patent/ES2156287T3/es not_active Expired - Lifetime
- 1996-07-09 AU AU66993/96A patent/AU699370B2/en not_active Ceased
- 1996-07-09 DK DK96927006T patent/DK0842170T3/da active
- 1996-07-09 US US08/983,059 patent/US5935974A/en not_active Expired - Fee Related
- 1996-07-09 KR KR1019980700107A patent/KR19990028807A/ko not_active Ceased
- 1996-07-09 PT PT96927006T patent/PT842170E/pt unknown
- 1996-07-09 WO PCT/EP1996/003099 patent/WO1997003065A1/en not_active Ceased
- 1996-07-09 CA CA002226851A patent/CA2226851A1/en not_active Abandoned
- 1996-07-12 AR ARP960103567A patent/AR003966A1/es active IP Right Grant
- 1996-07-29 TW TW085109218A patent/TW419477B/zh not_active IP Right Cessation
1998
- 1998-01-09 NO NO980109A patent/NO309765B1/no unknown
2001
- 2001-05-11 GR GR20010400699T patent/GR3035849T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
IL118768A0 (en)	1996-10-31
HUP9802762A2 (hu)	1999-10-28
MX9800368A (es)	1998-03-31
NZ315318A (en)	1999-10-28
NO309765B1 (no)	2001-03-26
CA2226851A1 (en)	1997-01-30
PL324451A1 (en)	1998-05-25
TR199800027T1 (xx)	1998-05-21
HUP9802762A3 (en)	2002-10-28
AU699370B2 (en)	1998-12-03
IL118768A (en)	2000-10-31
CN1091108C (zh)	2002-09-18
RU2162846C2 (ru)	2001-02-10
AR003966A1 (es)	1998-09-30
KR19990028807A (ko)	1999-04-15
BR9609330A (pt)	1999-05-25
EP0842170A1 (en)	1998-05-20
ATE199150T1 (de)	2001-02-15
TW419477B (en)	2001-01-21
AU6699396A (en)	1997-02-10
DE69611788D1 (de)	2001-03-22
EP0842170B1 (en)	2001-02-14
NO980109L (no)	1998-01-09
JPH11508907A (ja)	1999-08-03
ZA965691B (en)	1997-01-24
HK1010818A1 (en)	1999-07-02
US5935974A (en)	1999-08-10
NO980109D0 (no)	1998-01-09
PL183837B1 (pl)	2002-07-31
WO1997003065A1 (en)	1997-01-30
DK0842170T3 (da)	2001-06-18
CN1190965A (zh)	1998-08-19
CZ8398A3 (cs)	1998-06-17
PT842170E (pt)	2001-06-29
CZ288909B6 (cs)	2001-09-12
ES2156287T3 (es)	2001-06-16
DE69611788T2 (de)	2001-08-02

Publication	Publication Date	Title
ZA962200B (en)	1996-10-30	Piperidine derivatives
ZA965691B (en)	1997-01-24	Diphenylmethylene piperidine derivatives
AP9400671A0 (en)	1994-10-31	Piperidine derivatives
NZ305444A (en)	1999-03-29	4-anilino-7-alkoxy-quinazoline derivatives
IL152383A0 (en)	2003-05-29	5-amino-3-cyano-4-ethylsulfinyl-1- phenyl-pyrazole derivatives
IL135376A0 (en)	2001-05-20	Hydroxyalkyl-phenyl derivatives
GB2306473A8 (en)	1997-05-28	Glucoxide derivatives
HU9603071D0 (en)	1996-12-30	Purin-6-one derivatives
HU9600876D0 (en)	1996-05-28	Benzonitril- and -fluoride derivatives
ZA952431B (en)	1995-12-19	New piperidine derivatives
AU7580796A (en)	1997-06-11	Piperidine and tetrahydropyridine derivatives
NZ332395A (en)	1999-02-25	Benzonthiazole derivatives
HUP9600107A3 (en)	1999-06-28	9-substituted-2-(2-n-alkoxy-phenyl)-purin-6-one derivatives
SI0758644T1 (en)	2004-04-30	Sulfonyl- or sulfinyl-benzoyl-guanidine derivatives
HUP9900672A3 (en)	2001-11-28	Pyrroloazepine derivatives
SG60005A1 (en)	1999-02-22	1-Fluorocyclohexene-difluorophenyl derivatives
IL123621A0 (en)	1998-10-30	Diarylalkenylamine derivatives
GR3035577T3 (en)	2001-06-29	Benzisothiazolyl-substituted aminomethylchroman derivatives
IL117858A0 (en)	1996-08-04	4-Indolypiperazinyl derivatives
IL118161A0 (en)	1996-09-12	Novel 4-diphenylmethyl piperidine derivatives
GR3036572T3 (en)	2001-12-31	4-amino-benzoylguanidine derivatives
HU9602324D0 (en)	1996-10-28	Piperidinyl-methyl-oxazolidinon derivatives
EP0754668A3 (de)	1997-08-27	Fluorbenzylether-Derivate
PL324892A1 (en)	1998-06-22	Aza-antracyclinone derivatives
ZA972329B (en)	1998-09-18	Piperidine derivatives

Legal Events

Date	Code	Title	Description
2004-02-05	ML	Lapse due to non-payment of fees