GR3034510T3 - Combined cellular and immunosuppressive therapies. - Google Patents
Combined cellular and immunosuppressive therapies.Info
- Publication number
- GR3034510T3 GR3034510T3 GR20000402200T GR20000402200T GR3034510T3 GR 3034510 T3 GR3034510 T3 GR 3034510T3 GR 20000402200 T GR20000402200 T GR 20000402200T GR 20000402200 T GR20000402200 T GR 20000402200T GR 3034510 T3 GR3034510 T3 GR 3034510T3
- Authority
- GR
- Greece
- Prior art keywords
- cells
- foreign
- immunosuppressive therapies
- combined cellular
- reduced
- Prior art date
Links
- 238000002659 cell therapy Methods 0.000 title abstract 2
- 230000001413 cellular effect Effects 0.000 title 1
- 238000002650 immunosuppressive therapy Methods 0.000 title 1
- 102000008949 Histocompatibility Antigens Class I Human genes 0.000 abstract 1
- 108010088652 Histocompatibility Antigens Class I Proteins 0.000 abstract 1
- 230000000735 allogeneic effect Effects 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 239000003018 immunosuppressive agent Substances 0.000 abstract 1
- 229940125721 immunosuppressive agent Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/001—Preparations to induce tolerance to non-self, e.g. prior to transplantation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Transplantation (AREA)
- Developmental Biology & Embryology (AREA)
- Mycology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78107591A | 1991-10-21 | 1991-10-21 | |
| PCT/US1992/008969 WO1993007887A1 (en) | 1991-10-21 | 1992-10-14 | Combined cellular and immunosuppressive therapies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR3034510T3 true GR3034510T3 (en) | 2000-12-29 |
Family
ID=25121603
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR20000402200T GR3034510T3 (en) | 1991-10-21 | 2000-09-28 | Combined cellular and immunosuppressive therapies. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5670148A (el) |
| EP (1) | EP0610345B1 (el) |
| JP (1) | JPH07500343A (el) |
| AT (1) | ATE194494T1 (el) |
| AU (1) | AU2883192A (el) |
| CA (1) | CA2121487A1 (el) |
| DE (1) | DE69231250T2 (el) |
| DK (1) | DK0610345T3 (el) |
| ES (1) | ES2150424T3 (el) |
| GR (1) | GR3034510T3 (el) |
| WO (1) | WO1993007887A1 (el) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2683725B1 (fr) * | 1991-11-15 | 1995-07-07 | Pasteur Institut | Composition cellulaire pour le traitement des organismes humains ou animaux. |
| US20030152909A1 (en) * | 1994-11-16 | 2003-08-14 | Mitrani Eduardo N. | In vitro micro-organs, and uses related thereto |
| US6063375A (en) * | 1996-09-10 | 2000-05-16 | Medical University Of South Carolina | Semiallogeneic cell hybrids and related methods for treating cancer |
| US7687057B2 (en) | 1998-01-09 | 2010-03-30 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | In vitro micro-organs, and uses related thereto |
| AU741602B2 (en) * | 1998-02-02 | 2001-12-06 | Johns Hopkins University School Of Medicine, The | A universal immunomodulatory cytokine-expressing bystander cell line and related compositions and methods of manufacture and use |
| AU2007229367B2 (en) * | 1999-06-25 | 2011-02-03 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | In Vitro Micro-Organs and Uses Related Thereto |
| AU2003271042C1 (en) * | 1999-06-25 | 2008-06-26 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | In Vitro Micro-Organs and Uses Related Thereto |
| US20060127366A1 (en) * | 1999-06-25 | 2006-06-15 | Mitrani Eduardo N | Method and device for inducing biological processes by micro-organs |
| US20030152562A1 (en) * | 2001-10-23 | 2003-08-14 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Vitro micro-organs, and uses related thereto |
| US7468242B2 (en) | 2001-11-05 | 2008-12-23 | Medgenics, Inc. | Dermal micro organs, methods and apparatuses for producing and using the same |
| US8088568B2 (en) | 2001-11-05 | 2012-01-03 | Medgentics, Inc. | Dermal micro-organs, methods and apparatuses for producing and using the same |
| US8501396B2 (en) | 2001-11-05 | 2013-08-06 | Medgenics Medical Israel Ltd. | Dermal micro-organs, methods and apparatuses for producing and using the same |
| EP2377404A1 (en) | 2003-05-01 | 2011-10-19 | Medgenics, Inc. | A dermal micro-organ which is an explant of living tissue |
| US8454948B2 (en) | 2006-09-14 | 2013-06-04 | Medgenics Medical Israel Ltd. | Long lasting drug formulations |
| US9127084B2 (en) | 2006-09-14 | 2015-09-08 | Medgenics Medical Israel Ltd. | Long lasting drug formulations |
| KR101470472B1 (ko) | 2006-09-14 | 2014-12-09 | 메드제닉스 메디칼 이스라엘 리미티드 | 장기 지속형 약물 제형 |
| US9731023B2 (en) | 2010-09-08 | 2017-08-15 | Board Of Regents, The University Of Texas System | Somatostatin receptor-based cancer therapy |
| US20150320799A1 (en) | 2012-12-20 | 2015-11-12 | Purdue Research Foundation | Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics |
| JP7282521B2 (ja) | 2016-04-08 | 2023-05-29 | パーデュー・リサーチ・ファウンデイション | Ｃａｒ ｔ細胞療法のための方法および組成物 |
| EP3579870A4 (en) | 2017-02-07 | 2020-12-30 | Seattle Children's Hospital (DBA Seattle Children's Research Institute) | PHOSPHOLIPID ETHER (PLE) T CAR-LYMPHOCYTE TUMOR (CTCT) TARGETING AGENTS |
| WO2018160622A1 (en) | 2017-02-28 | 2018-09-07 | Endocyte, Inc. | Compositions and methods for car t cell therapy |
| AU2019209432A1 (en) | 2018-01-22 | 2020-08-06 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Methods of use for CAR T cells |
| CN111936518A (zh) | 2018-02-06 | 2020-11-13 | 西雅图儿童医院（Dba西雅图儿童研究所） | 对fl-ple标记的肿瘤表现出最佳的t细胞功能的荧光素特异性car |
| WO2019165237A1 (en) | 2018-02-23 | 2019-08-29 | Endocyte, Inc. | Sequencing method for car t cell therapy |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4769317A (en) * | 1983-06-14 | 1988-09-06 | Hefton John M | Process for growing human epidermis, product thereof |
| US4980286A (en) * | 1985-07-05 | 1990-12-25 | Whitehead Institute For Biomedical Research | In vivo introduction and expression of foreign genetic material in epithelial cells |
| US5175004A (en) * | 1988-12-27 | 1992-12-29 | Matsumura Kenneth N | Propagatable, new combinant cells for cellular replacement therapy |
| US5283058A (en) * | 1990-08-30 | 1994-02-01 | The General Hospital Corporation | Methods for inhibiting rejection of transplanted tissue |
| EP0591462B1 (en) * | 1991-07-15 | 2003-04-16 | Oklahoma Medical Research Foundation | Universal donor cells |
-
1992
- 1992-10-14 AT AT92922624T patent/ATE194494T1/de not_active IP Right Cessation
- 1992-10-14 DE DE69231250T patent/DE69231250T2/de not_active Expired - Fee Related
- 1992-10-14 EP EP92922624A patent/EP0610345B1/en not_active Expired - Lifetime
- 1992-10-14 DK DK92922624T patent/DK0610345T3/da active
- 1992-10-14 WO PCT/US1992/008969 patent/WO1993007887A1/en not_active Ceased
- 1992-10-14 ES ES92922624T patent/ES2150424T3/es not_active Expired - Lifetime
- 1992-10-14 JP JP5507889A patent/JPH07500343A/ja not_active Ceased
- 1992-10-14 AU AU28831/92A patent/AU2883192A/en not_active Abandoned
- 1992-10-14 CA CA002121487A patent/CA2121487A1/en not_active Abandoned
-
1994
- 1994-09-28 US US08/314,452 patent/US5670148A/en not_active Expired - Fee Related
-
2000
- 2000-09-28 GR GR20000402200T patent/GR3034510T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE194494T1 (de) | 2000-07-15 |
| EP0610345A1 (en) | 1994-08-17 |
| ES2150424T3 (es) | 2000-12-01 |
| DE69231250D1 (de) | 2000-08-17 |
| DE69231250T2 (de) | 2001-03-15 |
| DK0610345T3 (da) | 2000-10-23 |
| US5670148A (en) | 1997-09-23 |
| CA2121487A1 (en) | 1993-04-29 |
| EP0610345B1 (en) | 2000-07-12 |
| AU2883192A (en) | 1993-05-21 |
| WO1993007887A1 (en) | 1993-04-29 |
| EP0610345A4 (en) | 1997-01-15 |
| JPH07500343A (ja) | 1995-01-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ML | Lapse due to non-payment of fees |