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GR3034351T3 - Method for increasing blood-brain barrier permeability. - Google Patents

Method for increasing blood-brain barrier permeability.

Info

Publication number
GR3034351T3
GR3034351T3 GR20000402039T GR20000402039T GR3034351T3 GR 3034351 T3 GR3034351 T3 GR 3034351T3 GR 20000402039 T GR20000402039 T GR 20000402039T GR 20000402039 T GR20000402039 T GR 20000402039T GR 3034351 T3 GR3034351 T3 GR 3034351T3
Authority
GR
Greece
Prior art keywords
brain barrier
blood
barrier permeability
permeability
increasing blood
Prior art date
Application number
GR20000402039T
Other languages
English (en)
Inventor
Bernard Malfroy-Camine
Janet L Smart
Original Assignee
Alkermes Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alkermes Inc filed Critical Alkermes Inc
Publication of GR3034351T3 publication Critical patent/GR3034351T3/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/18Kallidins; Bradykinins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/243Platinum; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/043Kallidins; Bradykinins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Display Devices Of Pinball Game Machines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GR20000402039T 1990-04-23 2000-09-06 Method for increasing blood-brain barrier permeability. GR3034351T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/512,913 US5112596A (en) 1990-04-23 1990-04-23 Method for increasing blood-brain barrier permeability by administering a bradykinin agonist of blood-brain barrier permeability
PCT/US1991/002772 WO1991016355A1 (en) 1990-04-23 1991-04-23 Method for increasing blood-brain barrier permeability

Publications (1)

Publication Number Publication Date
GR3034351T3 true GR3034351T3 (en) 2000-12-29

Family

ID=24041129

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20000402039T GR3034351T3 (en) 1990-04-23 2000-09-06 Method for increasing blood-brain barrier permeability.

Country Status (11)

Country Link
US (1) US5112596A (el)
EP (1) EP0528891B1 (el)
JP (1) JPH05506859A (el)
AT (1) ATE194289T1 (el)
AU (1) AU650020B2 (el)
CA (1) CA2081308A1 (el)
DE (1) DE69132288T2 (el)
DK (1) DK0528891T3 (el)
ES (1) ES2147722T3 (el)
GR (1) GR3034351T3 (el)
WO (1) WO1991016355A1 (el)

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